School of Life Sciences

  • United Kingdom

Research Output 1968 2020

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Letter
55 Citations (Scopus)
272 Downloads (Pure)

USP7 small-molecule inhibitors interfere with ubiquitin binding

Kategaya, L., Di Lello, P., Rougé, L., Pastor, R., Clark, K. R., Drummond, J., Kleinheinz, T., Lin, E., Upton, J-P., Prakash, S., Heideker, J., McCleland, M., Ritorto, M. S., Alessi, D. R., Trost, M., Bainbridge, T. W., Kwok, M. C. M., Ma, T. P., Stiffler, Z., Brasher, B. & 24 others, Tang, Y., Jaishankar, P., Hearn, B. R., Renslo, A. R., Arkin, M. R., Cohen, F., Yu, K., Peale, F., Gnad, F., Chang, M. T., Klijn, C., Blackwood, E., Martin, S. E., Forrest, W. F., Ernst, J. A., Ndubaku, C., Wang, X., Beresini, M. H., Tsui, V., Schwerdtfeger, C., Blake, R. A., Murray, J., Maurer, T. & Wertz, I. E., 18 Oct 2017, In : Nature. 550, p. 534-538 5 p.

Research output: Contribution to journalLetter

Open Access
File
Ubiquitin-Specific Proteases
Ubiquitin
Magnetic Resonance Spectroscopy
Tumor Suppressor Protein p53
Proteins
13 Citations (Scopus)

Triclosan is minimally effective in rodent malaria models

Baschong, W., Wittlin, S., Inglis, K. A., Fairlamb, A. H., Croft, S. L., Kumar, T. R. S., Fidock, D. A. & Brun, R., Jan 2011, In : Nature Medicine. 17, 1, p. 33-34 2 p.

Research output: Contribution to journalLetter

Toxin arrest

Stark, M. J. R., 9 Aug 1990, In : Nature. 346, 6284, p. 518-518 1 p.

Research output: Contribution to journalLetter

6 Citations (Scopus)
46 Downloads (Pure)

The structure of a Trypanosoma cruzi glucose-6-phosphate dehydrogenase reveals differences from the mammalian enzyme

Mercaldi, G. F., Dawson, A., Hunter, W. N. & Cordeiro, A. T., 19 Aug 2016, In : FEBS Letters. 590, 16, p. 2776-2786 11 p.

Research output: Contribution to journalLetter

Open Access
File
Glucosephosphate Dehydrogenase
Trypanosoma cruzi
NADP
Pentoses
Pentose Phosphate Pathway
25 Citations (Scopus)

The Seyfert AGN RX J0136.9-3510 and the spectral state of super Eddington accretion flows

Jin, C., Done, C., Ward, M., Gierliński, M. & Mullaney, J., Sep 2009, In : Monthly Notices of the Royal Astronomical Society: Letters. 398, 1, p. L16-L20 5 p.

Research output: Contribution to journalLetter

active galactic nuclei
accretion
oscillation
H beta line
x rays
14 Citations (Scopus)

The role of ATM in response to metformin treatment and activation of AMPK reply

Zhou, K., Bellenguez, C., Sutherland, C., Hardie, G., Palmer, C., Donnelly, P. & Pearson, E., Apr 2012, In : Nature Genetics. 44, 4, p. 361-362 2 p.

Research output: Contribution to journalLetter

70 Citations (Scopus)

The limits of protein secondary structure prediction accuracy from multiple sequence alignment

Russell, R. B. & Barton, G. J., 20 Dec 1993, In : Journal of Molecular Biology. 234, 4, p. 951-957 7 p.

Research output: Contribution to journalLetter

Secondary Protein Structure
Sequence Alignment
src Homology Domains
Proteins
Annexins
31 Citations (Scopus)

The iron K feature in narrow line Seyfert 1 galaxies: Evidence for a P Cygni profile?

Done, C., Sobolewska, M. A., Gierliński, M. & Schurch, N. J., 1 Jan 2007, In : Monthly Notices of the Royal Astronomical Society: Letters. 374, 1, p. L15-L19 5 p.

Research output: Contribution to journalLetter

Open Access
ionization
galaxies
iron
profiles
K lines

"The immortal DNA strand" - difficult to digest? Response

Nathke, I., 2 Apr 2010, In : Cell Stem Cell. 6, 4, p. 299-299 1 p.

Research output: Contribution to journalLetter

3 Citations (Scopus)
124 Downloads (Pure)

Striate palmoplantar keratoderma resulting from a missense mutation in DSG1

Vodo, D., O'Toole, E. A., Malchin, N., Lahav, A., Adir, N., Sarig, O., Green, K., Smith, F. J. D. & Sprecher, E., 17 Sep 2018, In : British Journal of Dermatology. 179, 3, p. 755-757 3 p.

Research output: Contribution to journalLetter

Open Access
File
Palmoplantar Keratoderma
Genetic Databases
Missense Mutation

Skin fragility, woolly hair syndrome with a desmoplakin mutation – a case from India

Peter, D. C. V., Thomas, M., Wilson, N. J. & Smith, F. J. D., Sep 2018, In : International Journal of Dermatology. 57, 9, p. e73-e75 3 p.

Research output: Contribution to journalLetter

2 Citations (Scopus)

Sign-time distribution for a random walker with a drifting boundary

Newman, T. J., 16 Mar 2001, In : Journal of Physics A: Mathematical and General. 34, 10, p. L89-L94 6 p.

Research output: Contribution to journalLetter

Moving Boundary
derivation
48 Citations (Scopus)

Role of fungi in the biogeochemical fate of depleted uranium

Fomina, M., Charnock, J. M., Hillier, S., Alvarez, R., Livens, F. & Gadd, G. M., 6 May 2008, In : Current Biology. 18, 9, p. R375-R377 3 p.

Research output: Contribution to journalLetter

Response: Genetic polymorphism of Fc

Woof, J. M., 10 Mar 2006, In : Science. 311, 5766, p. 1377 1 p.

Research output: Contribution to journalLetter

Resolution of the plantar hyperkeratosis of pachyonychia congenita during chemotherapy for Ewing sarcoma

Higgins, E., Capra, M., Schwartz, M. E., Smith, F. J. D., McLean, W. H. I. & Irvine, A. D., Dec 2013, In : British Journal of Dermatology. 169, 6, p. 1357-1360 4 p.

Research output: Contribution to journalLetter

Open Access
3 Citations (Scopus)

Reply to Nakov et al. Model choice requires biological insight when studying the ancestral habitat of photosynthetic eukaryotes

Sánchez-Baracaldo, P., Bianchini, G., Huelsenbeck, J. P., Raven, J. A., Pisani, D. & Knoll, A. H., 12 Dec 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 50, p. E10608-E10609 2 p.

Research output: Contribution to journalLetter

Reply to Jiménez-Alonso et al., Schooling and Zhao, and Mortazavi: Further discussion on the immunological model of carcinogenesis

Palmer, S., Albergante, L., Blackburn, C. C. & Newman, T. J., 8 May 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 19, p. E4319-E4321 3 p.

Research output: Contribution to journalLetter

Open Access
23 Citations (Scopus)

Reply: A unified classification system for eukaryotic transposable elements should reflect their phylogeny

Wicker, T., Sabot, F., Hua-Van, A., Bennetzen, J. L., Capy, P., Chalhoub, B., Flavell, A., Leroy, P., Morgante, M., Panaud, O., Paux, E., SanMiguel, P. & Schulman, A. H., Apr 2009, In : Nature Reviews Genetics. 10, 4, p. 276 1 p.

Research output: Contribution to journalLetter

14 Citations (Scopus)

Recessive mutations in the gene encoding frizzled 6 cause twenty nail dystrophy: Expanding the differential diagnosis for pachyonychia congenita

Wilson, N. J., Hansen, C. D., Azkur, D., Kocabas, C. N., Metin, A., Coskun, Z., Schwartz, M. E., Hull, P. R., McLean, W. H. I. & Smith, F. J. D., Apr 2013, In : Journal of Dermatological Science. 70, 1, p. 58-60 3 p.

Research output: Contribution to journalLetter

53 Citations (Scopus)

Reanalysis of phosphoproteomics data uncovers ADP-ribosylation sites

Matic, I., Ahel, I. & Hay, R. T., Aug 2012, In : Nature Methods. 9, 8, p. 771-772 2 p.

Research output: Contribution to journalLetter

17 Citations (Scopus)

Protein structure prediction

Barton, G. J. & Russell, R. B., 11 Feb 1993, In : Nature. 361, 6412, p. 505-506 2 p.

Research output: Contribution to journalLetter

360 Citations (Scopus)

Prediction of protein secondary structure and active sites using the alignment of homologous sequences

Zvelebil, M. J., Barton, G. J., Taylor, W. R. & Sternberg, M. J. E., 20 Jun 1987, In : Journal of Molecular Biology. 195, 4, p. 957-961 5 p.

Research output: Contribution to journalLetter

Secondary Protein Structure
Sequence Homology
Catalytic Domain
Insertional Mutagenesis
Enzymes
240 Citations (Scopus)

Piezo1 integration of vascular architecture with physiological force

Li, J., Hou, B., Tumova, S., Muraki, K., Bruns, A., Ludlow, M. J., Sedo, A., Hyman, A. J., McKeown, L., Young, R. S., Yuldasheva, N. Y., Majeed, Y., Wilson, L. A., Rode, B., Bailey, M. A., Kim, H. R., Fu, Z., Carter, D. A. L., Bilton, J., Imrie, H. & 8 others, Ajuh, P., Dear, T. N., Cubbon, R. M., Kearney, M. T., Prasad, K. R., Evans, P. C., Ainscough, J. F. X. & Beech, D. J., 13 Nov 2014, In : Nature. 515, 7526, p. 279-82 4 p.

Research output: Contribution to journalLetter

Blood Vessels
Endothelial Cells
Calcium
Haploinsufficiency
Cell Polarity
1 Citation (Scopus)
98 Downloads (Pure)

Patients with atopic dermatitis with filaggrin loss-of-function mutations show good but lower responses to immunosuppressive treatment

Roekevisch, E., Leeflang, M. M. G., Schram, M. E., Campbell, L. E., Irwin McLean, W. H., Kezic, S., Bos, J. D., Spuls, P. I. & Middelkamp-Hup, M. A., 8 Jan 2018, In : British Journal of Dermatology. 177, 6, p. 1745-1746 2 p.

Research output: Contribution to journalLetter

Open Access
File
Atopic Dermatitis
Immunosuppressive Agents
Mutation
Randomized Controlled Trials
Therapeutics
1 Citation (Scopus)
6 Downloads (Pure)

Painful punctate palmoplantar keratoderma due to heterozygous mutations in AAGAB

Zamiri, M., Wilson, N. J., Mackenzie, A., Sobey, G., Leitch, C. & Smith, F. J. D., 19 Nov 2018, In : The British journal of dermatology. 7 p.

Research output: Contribution to journalLetter

Open Access
File
Palmoplantar Keratoderma
Mutation
Genes
Weight-Bearing
Carrier Proteins
7 Citations (Scopus)

Open Lab as a source of hits and leads against tuberculosis, malaria and kinetoplastid diseases

Ballell, L., Strange, M., Cammack, N., Fairlamb, A. H. & Borysiewicz, L., Apr 2016, In : Nature Reviews Drug Discovery. 15, 4, 3 p., 292.

Research output: Contribution to journalLetter

Novel mutations in desmoglein 1: Focal palmoplantar keratoderma in milder phenotypes

Zamiri, M., Wilson, N. J., O'Toole, E. A. & Smith, F. J. D., 1 Sep 2019, In : British Journal of Dermatology. 181, 3, p. 618-620 3 p.

Research output: Contribution to journalLetter

Desmoglein 1
Keratin-16
Keratin-1
Desmoplakins
Palmoplantar Keratoderma
3 Citations (Scopus)
86 Downloads (Pure)

Novel autosomal dominant mutation in loricrin presenting as prominent ichthyosis

Pohler, E., Cunningham, F., Sandilands, A., Cole, C., Digby, S., McMillan, J. R., Aristodemou, S., McGrath, J. A., Smith, F. J. D., Mclean, W. H. I., Munro, C. S. & Zamiri, M., 26 Nov 2015, In : British Journal of Dermatology. 173, 5, p. 1292-1294 4 p.

Research output: Contribution to journalLetter

Open Access
File
9 Citations (Scopus)
168 Downloads (Pure)

New and recurrent AAGAB mutations in punctate palmoplantar keratoderma

Pohler, E., Huber, M., Boonen, S. E., Zamiri, M., Gregersen, P. A., Sommerlund, M., Ramsing, M., Hohl, D., McLean, W. H. I. & Smith, F. J., 18 Aug 2014, In : British Journal of Dermatology. 171, 2, p. 433-436 4 p.

Research output: Contribution to journalLetter

Open Access
File
Palmoplantar Keratoderma
Genetic Databases
Mutation
Genes
Chromosomes
242 Citations (Scopus)

Natural variation in a homolog of Antirrhinum CENTRORADIALIS contributed to spring growth habit and environmental adaptation in cultivated barley

Comadran, J., Kilian, B., Russell, J., Ramsay, L., Stein, N., Ganal, M., Shaw, P., Bayer, M., Thomas, W., Marshall, D., Hedley, P., Tondelli, A., Pecchioni, N., Francia, E., Korzun, V., Walther, A. & Waugh, R., Dec 2012, In : Nature Genetics. 44, 12, p. 1388-1392 5 p.

Research output: Contribution to journalLetter

7 Citations (Scopus)
63 Downloads (Pure)

Mutations in POGLUT1 in Galli-Galli/Dowling Degos-disease

Wilson, N. J., Cole, C., Kroboth, K., Hunter, W. N., Mann, J. A., Irwin McLean, W. H., Kernland Lang, K., Beltraminelli, H., Sabroe, R. A., Tiffin, N., Sobey, G. J., Borradori, L., Simpson, E. & Smith, F. J. D., Jan 2017, In : British Journal of Dermatology. 176, 1, p. 270-274 5 p.

Research output: Contribution to journalLetter

Open Access
File
Glucosyltransferases
Genetic Databases
Mutation
Proteins
Keratin-5
169 Citations (Scopus)

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D. P., Curtin, J. A., Bønnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A. C., Thyssen, J. P., Den Dekker, H. T., Ferreira, M. A., Altmaier, E., Sleiman, P. M. A., Xiao, F. L., Gonzalez, J. R., Marenholz, I. & 130 others, Kalb, B., Pino-Yanes, M., Xu, C. J., Carstensen, L., Groen-Blokhuis, M. M., Venturini, C., Pennell, C. E., Barton, S. J., Levin, A. M., Curjuric, I., Bustamante, M., Kreiner-Møller, E., Lockett, G. A., Bacelis, J., Bunyavanich, S., Myers, R. A., Matanovic, A., Kumar, A., Tung, J. Y., Hirota, T., Kubo, M., McArdle, W. L., Henderson, A. J., Kemp, J. P., Zheng, J., Smith, G. D., Rüschendorf, F., Bauerfeind, A., Lee-Kirsch, M. A., Arnold, A., Homuth, G., Schmidt, C. O., Mangold, E., Cichon, S., Keil, T., Rodríguez, E., Peters, A., Franke, A., Lieb, W., Novak, N., Fölster-Holst, R., Horikoshi, M., Pekkanen, J., Sebert, S., Husemoen, L. L., Grarup, N., De Jongste, J. C., Rivadeneira, F., Hofman, A., Jaddoe, V. W. V., Pasmans, S. G. M. A., Elbert, N. J., Uitterlinden, A. G., Marks, G. B., Thompson, P. J., Matheson, M. C., Robertson, C. F., Ried, J. S., Li, J., Zuo, X. B., Zheng, X. D., Yin, X. Y., Sun, L. D., McAleer, M. A., O'Regan, G. M., Fahy, C. M. R., Campbell, L. E., Macek, M., Kurek, M., Hu, D., Eng, C., Postma, D. S., Feenstra, B., Geller, F., Hottenga, J. J., Middeldorp, C. M., Hysi, P., Bataille, V., Spector, T., Tiesler, C. M. T., Thiering, E., Pahukasahasram, B., Yang, J. J., Imboden, M., Huntsman, S., Vilor-Tejedor, N., Relton, C. L., Myhre, R., Nystad, W., Custovic, A., Weiss, S. T., Meyers, D. A., Söderhäll, C., Melén, E., Ober, C., Raby, B. A., Simpson, A., Jacobsson, B., Holloway, J. W., Bisgaard, H., Sunyer, J., Probst-Hensch, N. M., Williams, L. K., Godfrey, K. M., Wang, C. A., Boomsma, D. I., Melbye, M., Koppelman, G. H., Jarvis, D., McLean, W. H. I., Irvine, A. D., Zhang, X. J., Hakonarson, H., Gieger, C., Burchard, E. G., Martin, N. G., Duijts, L., Linneberg, A., Jarvelin, M. R., Nöthen, M. M., Lau, S., Hübner, N., Lee, Y. A., Tamari, M., Hinds, D. A., Glass, D., Brown, S. J., Heinrich, J., Evans, D. M. & Weidinger, S., Dec 2015, In : Nature Genetics. 47, 12, p. 1449-1456 8 p.

Research output: Contribution to journalLetter

Genome-Wide Association Study
Atopic Dermatitis
Genetic Association Studies
Hispanic Americans
Skin Diseases
39 Citations (Scopus)

mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

Zabala-Letona, A., Arruabarrena-Aristorena, A., Martín-Martín, N., Fernandez-Ruiz, S., Sutherland, J. D., Clasquin, M., Tomas-Cortazar, J., Jimenez, J., Torres, I., Quang, P., Ximenez-Embun, P., Bago, R., Ugalde-Olano, A., Loizaga-Iriarte, A., Lacasa-Viscasillas, I., Unda, M., Torrano, V., Cabrera, D., van Liempd, S. M., Cendon, Y. & 44 others, Polentinos-Castro, E., Murray, S., Revandkar, A., Alimonti, A., Zhang, Y., Barnett, A., Lein, G., Pirman, D., Cortazar, A. R., Arreal, L., Prudkin, L., Astobiza, I., Valcarcel-Jimenez, L., Zuñiga-García, P., Fernandez-Dominguez, I., Piva, M., Caro-Maldonado, A., Sánchez-Mosquera, P., Castillo-Martín, M., Serra, V., Beraza, N., Gentilella, A., Thomas, G., Azkargorta, M., Elortza, F., Farràs, R., Olmos, D., Efeyan, A., Anguita, J., Muñoz, J., Falcón-Pérez, J. M., Barrio, R., Macarulla, T., Mato, J. M., Martinez-Chantar, M. L., Cordon-Cardo, C., Aransay, A. M., Marks, K., Baselga, J., Tabernero, J., Nuciforo, P., Manning, B. D., Marjon, K. & Carracedo, A., 6 Jul 2017, In : Nature. 547, 7661, p. 109-113 22 p.

Research output: Contribution to journalLetter

Adenosylmethionine Decarboxylase
Polyamines
Prostatic Neoplasms
Neoplasms
Metabolomics

Misleading radiograph

Ogden, G., Lobban, T. & Liu, Y. C., 9 Mar 1991, In : British Dental Journal. 170, 5, p. 174 1 p.

Research output: Contribution to journalLetter

Open Access
1 Citation (Scopus)
54 Downloads (Pure)

MD simulation of high-resolution X-ray structures reveals post-translational modification dependent conformational changes in HSF-DNA interaction

Feng, H., Wang, S., Guo, L., Punekar, A. S., Ladenstein, R., Wang, D-C. & Liu, W., Dec 2016, In : Protein and Cell. 7, 12, p. 916-920 5 p.

Research output: Contribution to journalLetter

Open Access
File

Male genital lichen sclerosus and filaggrin

Shim, T. N., Brown, S. J., Francis, N. D., Dinneen, M., Hawkins, D., Muneer, A., Minhas, S., McLean, W. H. I. & Bunker, C. B., 17 Jun 2019, In : Clinical and Experimental Dermatology. 2 p.

Research output: Contribution to journalLetter

Lichen Sclerosus et Atrophicus
Genitalia
Autoimmunity
Skin Diseases
Epidermis
112 Citations (Scopus)

Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis

Wen, Y., Liu, Y., Xu, Y., Zhao, Y., Hua, R., Wang, K., Sun, M., Li, Y., Yang, S., Zhang, X-J., Kruse, R., Cichon, S., Betz, R. C., Noethen, M. M., van Steensel, M. A. M., van Geel, M., Steijlen, P. M., Hohl, D., Huber, M., Dunnill, G. S. & 20 others, Kennedy, C., Messenger, A., Munro, C. S., Terrinoni, A., Hovnanian, A., Bodemer, C., de Prost, Y., Paller, A. S., Irvine, A. D., Sinclair, R., Green, J., Shang, D., Liu, Q., Luo, Y., Jiang, L., Chen, H-D., Lo, W. H-Y., McLean, W. H. I., He, C-D. & Zhang, X., Feb 2009, In : Nature Genetics. 41, 2, p. 228-233 6 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)
96 Downloads (Pure)

Keratin 6b variant p.Gly499Ser reported in delayed-onset pachyonychia congenita is a non-pathogenic polymorphism

Smith, F. J. D. & McLean, W. H. I., 3 Dec 2017, In : Journal of Dermatology. 44, 12, p. e312 1 p.

Research output: Contribution to journalLetter

Open Access
File
29 Citations (Scopus)

Is NMR fragment screening fine-tuned to assess druggability of protein-protein interactions?

Dias, D. M., Van Molle, I., Baud, M. G. J., Galdeano, C., Geraldes, C. F. G. C. & Ciulli, A., 9 Jan 2014, In : ACS Medicinal Chemistry Letters. 5, 1, p. 23-28 6 p.

Research output: Contribution to journalLetter

Screening
Nuclear magnetic resonance
Proteins
Alpha Subunit Hypoxia-Inducible Factor 1
Ligands
2 Citations (Scopus)

In Vitro and In Vivo studies of trypanocidal activity of dietary isothiocyanates

Steverding, D., Michaels, S. & Read, K. D., 22 Jan 2014, In : Planta Medica.

Research output: Contribution to journalLetter

Isothiocyanates
Trypanosoma brucei brucei
Trypanosomiasis
HL-60 Cells
Parasitemia
158 Citations (Scopus)

INTERMEDIUM-C, a modifier of lateral spikelet fertility in barley, is an ortholog of the maize domestication gene TEOSINTE BRANCHED 1

Ramsay, L., Comadran, J., Druka, A., Marshall, D. F., Thomas, W. T. B., Macaulay, M., MacKenzie, K., Simpson, C., Fuller, J., Bonar, N., Hayes, P. M., Lundqvist, U., Franckowiak, J. D., Close, T. J., Muehlbauer, G. J. & Waugh, R., Feb 2011, In : Nature Genetics. 43, 2, p. 169-172 4 p.

Research output: Contribution to journalLetter

3913 Citations (Scopus)

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Cross, D. A. E., Alessi, D. R., Cohen, P., Andjelkovich, M. & Hemmings, B. A., 28 Dec 1995, In : Nature. 378, p. 785-789 5 p.

Research output: Contribution to journalLetter

Glycogen Synthase Kinase 3
Proto-Oncogene Proteins c-akt
Phosphotransferases
Insulin
90-kDa Ribosomal Protein S6 Kinases
43 Citations (Scopus)

Guidelines for reporting the use of gel electrophoresis in proteomics

Gibson, F., Anderson, L., Babnigg, G., Baker, M., Berth, M., Binz, P-A., Borthwick, A., Cash, P., Day, B. W., Friedman, D. B., Garland, D., Gutstein, H. B., Hoogland, C., Jones, N. A., Khan, A., Klose, J., Lamond, A. I., Lemkin, P. F., Lilley, K. S., Minden, J. & 10 others, Morris, N. J., Paton, N. W., Pisano, M. R., Prime, J. E., Rabilloud, T., Stead, D. A., Taylor, C. F., Voshol, H., Wipat, A. & Jones, A. R., Aug 2008, In : Nature Biotechnology. 26, 8, p. 863-864 2 p.

Research output: Contribution to journalLetter

744 Citations (Scopus)

Global analysis of protein phosphorylation in yeast

Ptacek, J., Devgan, G., Michaud, G., Zhu, H., Zhu, X., Fasolo, J., Guo, H., Jona, G., Breitkreutz, A., Sopko, R., McCartney, R. R., Schmidt, M. C., Rachidi, N., Lee, S-J., Mah, A. S., Meng, L., Stark, M. J. R., Stern, D. F., De Virgilio, C., Tyers, M. & 5 others, Andrews, B., Gerstein, M., Schweitzer, B., Predki, P. F. & Snyder, M., 1 Dec 2005, In : Nature. 438, 7068, p. 679-684 6 p.

Research output: Contribution to journalLetter

Yeasts
Phosphorylation
Phosphotransferases
Proteins
Fungal Proteins
48 Citations (Scopus)
207 Downloads (Pure)

Genomic analysis of 6,000-year-old cultivated grain illuminates the domestication history of barley

Mascher, M., J. Schuenemann, V., Davidovich, U., Marom, N., Himmelbach, A., Hübner, S., Korol, A., David, M., Reiter, E., Riehl, S., Schreiber, M., Vohr, S. H., Green, R. E., Dawson, I. K., Russell, J., Kilian, B., Muehlbauer, G. J., Waugh, R., Fahima, T., Krause, J. & 2 others, Weiss, E. & Stein, N., Sep 2016, In : Nature Genetics. 48, 9, p. 1089-1093 5 p.

Research output: Contribution to journalLetter

Open Access
File
Hordeum
Genome
Exome
Jordan
Gene Flow
93 Citations (Scopus)

Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei

Mony, B. M., MacGregor, P., Ivens, A., Rojas, F., Cowton, A., Young, J., Horn, D. & Matthews, K., 30 Jan 2014, In : Nature. 505, 7485, p. 681-685 5 p.

Research output: Contribution to journalLetter

Quorum Sensing
Trypanosoma brucei brucei
Dissection
Parasites
Genome
112 Citations (Scopus)
124 Downloads (Pure)

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

Zhang, C-S., Hawley, S. A., Zong, Y., Li, M., Wang, Z., Gray, A., Ma, T., Cui, J., Feng, J-W., Zhu, M., Wu, Y-Q., Li, T. Y., Ye, Z., Lin, S-Y., Yin, H., Piao, H-L., Hardie, D. G. & Lin, S-C., 3 Aug 2017, In : Nature. 548, 7665, p. 112-116 23 p.

Research output: Contribution to journalLetter

Open Access
File
Fructose-Bisphosphate Aldolase
AMP-Activated Protein Kinases
Glucose
Adenosine Monophosphate
Adenosine Diphosphate
1 Citation (Scopus)

Focal PPK secondary to a novel KRT6C mutation (Pachyonychia congenita-K6c)

Wee, J. S., Smith, F. J. D., Wilson, N. J. & O'Toole, E. A., 12 Aug 2016, In : Journal of the European Academy of Dermatology and Venereology. 30, 8, p. 1415-1416 2 p.

Research output: Contribution to journalLetter

10 Citations (Scopus)

Filaggrin null mutations are not a protective factor for acne vulgaris

Common, J. E. A., Brown, S. J., Haines, R. L., Goh, C. S. M., Chen, H., Balakrishnan, A., Munro, C. S., Tan, A. W. H., Tan, H. H., Tang, M. B. Y. & Lane, E. B., Jun 2011, In : Journal of Investigative Dermatology. 131, 6, p. 1378-1380 3 p.

Research output: Contribution to journalLetter