School of Life Sciences

  • United Kingdom

Research Output 1968 2020

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Review article
2019
1 Citation (Scopus)
147 Downloads (Pure)

Advances in targeted degradation of endogenous proteins

Roth, S., Fulcher, L. & Sapkota, G., 27 Apr 2019, In : Cellular and Molecular Life Sciences. 76, 14, p. 2761-2777 17 p.

Research output: Contribution to journalReview article

Open Access
File
Proteolysis
Proteins
Clustered Regularly Interspaced Short Palindromic Repeats
Gene Targeting
Protein Biosynthesis
1 Citation (Scopus)
38 Downloads (Pure)

A New Front in Microbial Warfare—Delivery of Antifungal Effectors by the Type VI Secretion System

Trunk, K., Coulthurst, S. & Quinn, J., Jun 2019, In : Journal of Fungi. 5, 2, p. 1-13 13 p., 50.

Research output: Contribution to journalReview article

Open Access
File
Weapons
Fungi
Microbiota
Autophagy
Gram-Negative Bacteria

Bifunctional chemical probes inducing protein-protein interactions

Maniaci, C. & Ciulli, A., Oct 2019, In : Current Opinion in Chemical Biology. 52, p. 145-156 12 p.

Research output: Contribution to journalReview article

Proteins
Ubiquitin-Protein Ligases
Molecules
Glues
Adhesives
18 Downloads (Pure)

Chromatin dynamics during interphase and cell division: similarities and differences between model and crop plants

Pecinka, A., Chevalier, C., Colas, I., Kalantidis, K., Varotto, S., Krugman, T., Michaelidis, C., Vallés, M-P., Muñoz, A. & Pradillo, M., 18 Oct 2019, In : Journal of Experimental Botany.

Research output: Contribution to journalReview article

Open Access
File
Interphase
interphase
Cell Division
Chromatin
chromatin
16 Downloads (Pure)

Classification of the nucleolytic ribozymes based upon catalytic mechanism

Lilley, D. M. J., 19 Aug 2019, In : F1000Research. 8, p. 1-10 10 p., 1462.

Research output: Contribution to journalReview article

Open Access
File
Catalytic RNA
Catalysis
RNA Cleavage
Acids
Hydroxyl Radical
74 Downloads (Pure)

Current and Future Prospects of Nitro-compounds as Drugs for Trypanosomiasis and Leishmaniasis

Fairlamb, A. H. & Patterson, S., 2019, In : Current Medicinal Chemistry. 26, 23, p. 4454 - 4475 22 p.

Research output: Contribution to journalReview article

Open Access
File
Nitro Compounds
Leishmaniasis
Trypanosomiasis
Parasites
Nifurtimox

Ecological implications of recently discovered and poorly studied sources of energy for the growth of true fungi especially in extreme environments

Gleason, F. H., Larkum, A. W. D., Raven, J. A., Manohar, C. S. & Lilje, O., Jun 2019, In : Fungal Ecology. 39, p. 380-387 8 p.

Research output: Contribution to journalReview article

fungus
rhodopsin
proton pump
fungi
energy

Global geographical and historical overview of cyanotoxin distribution and cyanobacterial poisonings

Svirčev, Z., Lalić, D., Bojadžija Savić, G., Tokodi, N., Drobac Backović, D., Chen, L., Meriluoto, J. & Codd, G. A., 26 Jul 2019, In : Archives of Toxicology. 53 p.

Research output: Contribution to journalReview article

Poisons
Poisoning
Animals
Cyanobacteria
Microcystins
1 Citation (Scopus)

How Plants Grow Up

McKim, S., 18 Mar 2019, In : Journal of Integrative Plant Biology . 61, 3, p. 257-277 21 p.

Research output: Contribution to journalReview article

Bearings (structural)
Hinges
Plant Structures
Inflorescence
Crops
2 Citations (Scopus)

Lignin engineering to improve saccharification and digestibility in grasses

Halpin, C., Apr 2019, In : Current Opinion in Biotechnology. 56, p. 223-229 7 p.

Research output: Contribution to journalReview article

Saccharification
Lignin
Poaceae
Biosynthesis
Livestock
4 Citations (Scopus)
19 Downloads (Pure)

mRNA cap regulation in mammalian cell function and fate

Galloway, A. & Cowling, V., Mar 2019, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1862, 3, p. 270-279 10 p.

Research output: Contribution to journalReview article

Open Access
File
Cells
Messenger RNA
RNA Polymerase II
RNA
Cell Physiological Phenomena
1 Citation (Scopus)

Nucleosome remodelling: structural insights into ATP-dependent remodelling enzymes

Sundaramoorthy, R., Apr 2019, In : Essays in Biochemistry. 63, 1, p. 45-58 14 p.

Research output: Contribution to journalReview article

Nucleosomes
Adenosine Triphosphate
Chromatin Assembly and Disassembly
DNA sequences
Enzymes

Outstanding questions in mitophagy: what we do and do not know

Montava Garriga, L. & Ganley, I., 9 Jul 2019, In : Journal of Molecular Biology.

Research output: Contribution to journalReview article

Mitochondrial Degradation
Autophagy
Neurodegenerative Diseases
Quality Control
Mitochondria
44 Downloads (Pure)

Pore timing: the evolutionary origins of the nucleus and nuclear pore complex

Field, M. C. & Rout, M. P., 3 Apr 2019, In : F1000Research. 8, p. 1-11 11 p., 369.

Research output: Contribution to journalReview article

Open Access
File
Nuclear Pore
Eukaryota
Bacteria
Archaea
Cell Nucleus
1 Citation (Scopus)
53 Downloads (Pure)

Probiotics in Extraintestinal Diseases: Current Trends and New Directions

Kiousi, D. E., Karapetsas, A., Karolidou, K., Panayiotidis, M. I., Pappa, A. & Galanis, A., 5 Apr 2019, In : Nutrients. 11, 4, p. 1-26 26 p., 788.

Research output: Contribution to journalReview article

Open Access
File
Probiotics
skin (animal)
probiotics
Illness Behavior
Bone and Bones
4 Citations (Scopus)
12 Downloads (Pure)

Roles of saprotrophic fungi in biodegradation or transformation of organic and inorganic pollutants in co-contaminated sites

Ceci, A., Pinzari, F., Russo, F., Persiani, A. M. & Gadd, G. M., 1 Jan 2019, In : Applied Microbiology and Biotechnology. 103, 1, p. 53-68 16 p.

Research output: Contribution to journalReview article

Open Access
File
Poisons
Environmental Biodegradation
Fungi
Soil
Metals
Proteome
Proteomics
Proteins
Chemical Fractionation
Cells
3 Citations (Scopus)
28 Downloads (Pure)

Therapeutic approaches to enhance PINK1/Parkin mediated mitophagy for the treatment of Parkinson's disease

Miller, S. & Muqit, M. M. K., 13 Jul 2019, In : Neuroscience Letters. 705, p. 7-13 7 p.

Research output: Contribution to journalReview article

Open Access
File
Mitochondrial Degradation
Parkinson Disease
Biomarkers
Ubiquitin-Specific Proteases
Therapeutics
8 Citations (Scopus)
91 Downloads (Pure)

The Type VI secretion system: a versatile bacterial weapon

Coulthurst, S., 1 May 2019, In : Microbiology. 165, 5, p. 503-515 13 p., 000789.

Research output: Contribution to journalReview article

Open Access
File
Weapons
Protein Array Analysis
Eukaryotic Cells
Gram-Negative Bacteria
Proteins

Tracing the evolutionary routes of plant-microbiota interactions

Escudero-Martinez, C. & Bulgarelli, D., 4 Nov 2019, In : Current Opinion in Microbiology. 49, p. 34-40 7 p.

Research output: Contribution to journalReview article

Microbiota
Soil
Plant Development
Genomics
Microbiology
2 Citations (Scopus)
58 Downloads (Pure)

Value of hospital antimicrobial stewardship programs [ASPs]: a systematic review

Nathwani, D., Varghese, D., Stephens, J., Ansari, W., Martin, S. & Charbonneau, C., 12 Feb 2019, In : Antimicrobial Resistance and Infection Control. 8, p. 1-13 13 p., 35.

Research output: Contribution to journalReview article

Open Access
File
Length of Stay
Cost Savings
Economics
Health Expenditures
Anti-Bacterial Agents

Ways to unwind with HROB, a new player in homologous recombination

Saredi, G. & Rouse, J., 1 Oct 2019, In : Genes & Development. 33, 19-20, p. 1293-1294 2 p.

Research output: Contribution to journalReview article

Homologous Recombination
DNA Repair
Minichromosome Maintenance Proteins
Double-Stranded DNA Breaks
DNA
2018
93 Downloads (Pure)

Adaptation and therapeutic exploitation of the plasma membrane of African trypanosomes

Quintana, J. F., Canavate Del Pino, R., Yamada, K., Zhang, N. & Field, M., 20 Jul 2018, In : Genes. 9, 7, 16 p., 368.

Research output: Contribution to journalReview article

Open Access
File
Immune Evasion
Trypanosomiasis
Cell Membrane
Membranes
Organelles
109 Citations (Scopus)
155 Downloads (Pure)

AMPK: Sensing Glucose as well as Cellular Energy Status

Lin, S-C. & Hardie, D., 6 Feb 2018, In : Cell Metabolism. 27, 2, p. 299-313 15 p.

Research output: Contribution to journalReview article

Open Access
File
AMP-Activated Protein Kinases
Glucose
Adenosine Triphosphatases
Fructose-Bisphosphate Aldolase
Adenosine Triphosphate
43 Citations (Scopus)
153 Downloads (Pure)

Antibiotics and antibiotic resistance genes in global lakes: A review and meta-analysis

Yang, Y., Song, W., Lin, H., Wang, W., Du, L. & Xing, W., Jul 2018, In : Environment International. 116, p. 60-73 14 p.

Research output: Contribution to journalReview article

Open Access
File
antibiotic resistance
meta-analysis
antibiotics
gene
lake
34 Citations (Scopus)
26 Downloads (Pure)

BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease

Prati, F., Bottegoni, G., Bolognesi, M. L. & Cavalli, A., 8 Feb 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 619-637 19 p.

Research output: Contribution to journalReview article

Open Access
File
Alzheimer Disease
Drug Discovery
Amyloid
Amyloid beta-Protein Precursor
Pharmaceutical Preparations

Blue carbon: past, present and future, with emphasis on macroalgae

Raven, J., Oct 2018, In : Biology Letters. 14, 10, p. 1-5 5 p., 20180336.

Research output: Contribution to journalReview article

Seaweed
macroalgae
Carbon
carbon
Temperature
3 Citations (Scopus)
92 Downloads (Pure)

Breaking Bad: How Viruses Subvert the Cell Cycle

Fan, Y., Sanyal, S. & Bruzzone, R., 19 Nov 2018, In : Frontiers in cellular and infection microbiology. 8, p. 1-28 28 p., 396.

Research output: Contribution to journalReview article

Open Access
File
Cell Cycle
Viruses
Antigen Presentation
Protein Transport
Humoral Immunity
17 Citations (Scopus)
135 Downloads (Pure)

Challenges and recent progress in drug discovery for tropical diseases

De Rycker, M., Baragaña, B., Duce, S. L. & Gilbert, I. H., 25 Jul 2018, In : Nature. 559, 7715, p. 498-506 9 p.

Research output: Contribution to journalReview article

Open Access
File
Drug Discovery
Pharmaceutical Preparations
Communicable Diseases
Economics
Morbidity
3 Citations (Scopus)

Conservation and Variation in Strategies for DNA Replication of Kinetoplastid Nuclear Genomes

Marques, C. A. & McCulloch, R., Feb 2018, In : Current Genomics. 19, 2, p. 98-109 12 p.

Research output: Contribution to journalReview article

Trypanosoma brucei brucei
DNA Replication
Origin Recognition Complex
Genome
Leishmania
15 Citations (Scopus)

Costs of acquiring phosphorus by vascular land plants: patterns and implications for plant coexistence

Raven, J. A., Lambers, H., Smith, S. E. & Westoby, M., 6 Feb 2018, In : New Phytologist. 217, 4, p. 1420-1427 8 p.

Research output: Contribution to journalReview article

Embryophyta
embryophytes
vascular plants
Phosphorus
Blood Vessels
5 Citations (Scopus)

Crops, Nitrogen, Water: Are Legumes Friend, Foe, or Misunderstood Ally?

Adams, M. A., Buchmann, N., Sprent, J., Buckley, T. N. & Turnbull, T. L., 1 Jun 2018, In : Trends in Plant Science. 23, 6, p. 539-550 12 p.

Research output: Contribution to journalReview article

nitrogen fixation
legumes
nitrogen
crops
water
99 Citations (Scopus)

Cyanobacterial blooms

Huisman, J., Codd, G. A., Paerl, H. W., Ibelings, B. W., Verspagen, J. M. H. & Visser, P. M., Aug 2018, In : Nature Reviews Microbiology. 16, 8, p. 471-483 13 p.

Research output: Contribution to journalReview article

Cyanobacteria
Eutrophication
Recreation
Fisheries
Climate Change
5 Citations (Scopus)

Direct and indirect approaches to identify drug modes of action

Tulloch, L. B., Menzies, S. K., Coron, R. P., Roberts, M. D., Florence, G. J. & Smith, T. K., Jan 2018, In : IUBMB Life. 70, 1, p. 9-22 14 p.

Research output: Contribution to journalReview article

Lead compounds
Drug Discovery
Pharmaceutical Preparations
Screening
Phenotype
5 Citations (Scopus)
65 Downloads (Pure)

Encystation: the most prevalent and underinvestigated differentiation pathway of eukaryotes

Schaap, P. & Schilde, C., 1 May 2018, In : Microbiology. 164, 5, p. 727-739 13 p., 000653.

Research output: Contribution to journalReview article

Open Access
File
Amoebozoa
Eukaryota
Cysts
Disease Eradication
Genes
6 Citations (Scopus)

Evolution and palaeophysiology of the vascular system and other means of long-distance transport

Raven, J. A., 5 Feb 2018, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 373, 1739, p. 1-14 14 p., 20160497.

Research output: Contribution to journalReview article

plant vascular system
mass flow
Lignin
Nutrients
Blood Vessels
4 Citations (Scopus)
68 Downloads (Pure)

Evolutionary origins and specialisation of membrane transport

Dacks, J. B. & Field, M. C., 1 Aug 2018, In : Current Opinion in Cell Biology. 53, p. 70-76 7 p.

Research output: Contribution to journalReview article

Open Access
File
Organelles
Intracellular Membranes
Membranes
Eukaryotic Cells
Cellular Structures
20 Downloads (Pure)

Evolution of protein trafficking in kinetoplastid parasites: complexity and pathogenesis

Venkatesh, D., Zhang, N., Zoltner, M., Canavate Del Pino, R. & Field, M. C., Nov 2018, In : Traffic. 19, 11, p. 803-812 10 p.

Research output: Contribution to journalReview article

Open Access
File
Protein Transport
Parasites
Kinetoplastida
Plastids
Host Specificity
7 Citations (Scopus)
4 Downloads (Pure)

Functional Amyloid and Other Protein Fibers in the Biofilm Matrix

Erskine, E., MacPhee, C. E. & Stanley-Wall, N., 12 Oct 2018, In : Journal of Molecular Biology. 430, 20, p. 3642-3656 15 p.

Research output: Contribution to journalReview article

Open Access
File
Amyloidogenic Proteins
Biofilms
Amyloid
Scleroproteins
Gram-Negative Bacteria
31 Citations (Scopus)
90 Downloads (Pure)

Keeping the home fires burning: AMP-activated protein kinase

Hardie, D. G., Jan 2018, In : Journal of the Royal Society Interface. 15, 138, 23 p., 20170774.

Research output: Contribution to journalReview article

Open Access
File
AMP-Activated Protein Kinases
Fires
Adenosine Triphosphate
Proteins
Adenosine Diphosphate
16 Citations (Scopus)

Laboratory evolution of protein conformational dynamics

Campbell, E. C., Correy, G. J., Mabbitt, P. D., Buckle, A. M., Tokuriki, N. & Jackson, C. J., Jun 2018, In : Current Opinion in Structural Biology. 50, p. 49-57 9 p.

Research output: Contribution to journalReview article

Proteins
7 Citations (Scopus)

Living off the Sun: chlorophylls, bacteriochlorophylls and rhodopsins

Larkum, A. W. D., Ritchie, R. J. & Raven, J. A., Mar 2018, In : Photosynthetica. 56, 1, p. 11-43 33 p.

Research output: Contribution to journalReview article

Viola
Bacteriochlorophylls
algae
rhodopsin
Rhodopsin
23 Citations (Scopus)
101 Downloads (Pure)

Mammalian mitophagy – from in vitro molecules to in vivo models

Rodger, C. E., McWilliams, T. G. & Ganley, I. G., Apr 2018, In : FEBS Journal. 285, 7, p. 1185-1202 18 p.

Research output: Contribution to journalReview article

Open Access
File
Mitochondrial Degradation
Mitochondria
Mammals
Cells
Health
87 Downloads (Pure)

Mapping determinants of cytokine signaling via protein engineering

Gorby, C., Martinez-Fabregas, J., Wilmes, S. & Moraga Gonzalez, I., 27 Sep 2018, In : Frontiers in Immunology. 9, 9 p., 2143.

Research output: Contribution to journalReview article

Open Access
File
Protein Engineering
Cytokines
Ligands
Janus Kinases
Cytokine Receptors
12 Citations (Scopus)
71 Downloads (Pure)

Melarsoprol Resistance in African Trypanosomiasis

Fairlamb, A. & Horn, D., Jun 2018, In : Trends in Parasitology. 34, 6, p. 481-492 12 p.

Research output: Contribution to journalReview article

Open Access
File
Melarsoprol
African Trypanosomiasis
Parasites
Drug Resistance
Pharmaceutical Preparations
25 Citations (Scopus)
21 Downloads (Pure)

Microbiological and environmental significance of metal-dependent anaerobic oxidation of methane

He, Z., Zhang, Q., Feng, Y., Luo, H., Pan, X. & Gadd, G. M., 1 Jan 2018, In : Science of the Total Environment. 610-611, p. 759-768 10 p.

Research output: Contribution to journalReview article

Open Access
File
Methane
methane
Metals
oxidation
Oxidation

Opportunities for, and limitations on, the functioning of very small cells, illustrated by the Chlorophyta and charophycean Streptophyta

Raven, J. A. & Beardall, J., 1 Jun 2018, In : Perspectives in Phycology. 5, 1, p. 1-12

Research output: Contribution to journalReview article

Chlorophyta
cell structures
cells
prediction
physics
21 Citations (Scopus)
156 Downloads (Pure)

Regulation of proteasome assembly and activity in health and disease

Rousseau, A. & Bertolotti, A., 2018, In : Nature Reviews Molecular Cell Biology. 19, 11, p. 697-712 16 p.

Research output: Contribution to journalReview article

Open Access
File
Proteasome Endopeptidase Complex
Health
Autophagy
Protein Transport
Quality Control
4 Citations (Scopus)
90 Downloads (Pure)

Social behaviours by Bacillus subtilis: quorum sensing, kin discrimination and beyond

Kalamara, M., Špacapan, M., Mandic‐Mulec, I. & Stanley-Wall, N., 1 Dec 2018, In : Molecular Microbiology. 110, 6, p. 863-878 16 p.

Research output: Contribution to journalReview article

Open Access
File
Quorum Sensing
Social Behavior
Bacillus subtilis
Bacteria
Nanotubes
7 Citations (Scopus)
74 Downloads (Pure)

The FAM83 family of proteins: from pseudo-PLDs to anchors for CK1 isoforms

Bozatzi, P. & Sapkota, G., 5 Jun 2018, In : Biochemical Society Transactions. 46, 3, p. 761-771 11 p.

Research output: Contribution to journalReview article

Open Access
File
Casein Kinase I
Anchors
Protein Isoforms
Phospholipase D
Protein Kinases