School of Life Sciences

  • United Kingdom

Research Output 1968 2020

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Review article
1986
161 Citations (Scopus)

Covalently attached phosphatidylinositol as a hydrophobic anchor for membrane-proteins

Low, M. G., Ferguson, M. A. J., Futerman, A. H. & Silman, I., 1986, In : Trends in Biochemical Sciences. 11, 5, p. 212-215 4 p.

Research output: Contribution to journalReview article

1987
131 Citations (Scopus)

Actions of synthetic and endogenous steroids on the GABAA receptor

Lambert, J. J., Peters, J. A. & Cottrell, G. A., 1 Jan 1987, In : Trends in Pharmacological Sciences. 8, 6, p. 224-227 4 p.

Research output: Contribution to journalReview article

GABA-A Receptors
Steroids
Steroid hormones
Hypnosis
gamma-Aminobutyric Acid
1988
921 Citations (Scopus)

Cell surface anchoring of proteins via glycosyl-phosphatidylinositol structures

Ferguson, M. A. J. & Williams, A. F., 1988, In : Annual Review of Biochemistry. 57, p. 285-320 36 p.

Research output: Contribution to journalReview article

1990
141 Citations (Scopus)

The plasmid-encoded killer system of Kluyveromyces lactis: A review

Stark, M. J. R., Boyd, A., Mileham, A. J. & Romanos, M. A., 1990, In : Yeast. 6, 1, p. 1-29 29 p.

Research output: Contribution to journalReview article

1994
12 Citations (Scopus)

Genetic analyses of yeast protein serine/threonine phosphatases

Stark, M. J. R., Black, S., Sneddon, A. A. & Andrews, P. D., 1 Apr 1994, In : FEMS Microbiology Letters. 117, 2, p. 121-130 10 p.

Research output: Contribution to journalReview article

230 Citations (Scopus)

Inhibitors of protein kinases and phosphatases

MacKintosh, C. & MacKintosh, R. W., 1994, In : Trends in Biochemical Sciences. 19, 11, p. 444-448 5 p.

Research output: Contribution to journalReview article

1995
670 Citations (Scopus)

Neurosteroids and GABAA receptor function

Lambert, J. J., Belelli, D., Hill-Venning, C. & Peters, J. A., Sep 1995, In : Trends in Pharmacological Sciences. 16, 9, p. 295-303 9 p.

Research output: Contribution to journalReview article

GABA-A Receptors
Neurotransmitter Agents
Steroids
Endocrine Glands
Modulators
1996
44 Citations (Scopus)

The role of carbohydrate in sperm-ZP3 adhesion

Chapman, N. R. & Barratt, C. L., 1 Oct 1996, In : Molecular Human Reproduction. 2, 10, p. 767-774 8 p.

Research output: Contribution to journalReview article

165 Citations (Scopus)

Yeast protein serine/threonine phosphatases: Multiple roles and diverse regulation

Stark, M. J. R., 1996, In : Yeast. 12, 16, p. 1647-1675 29 p.

Research output: Contribution to journalReview article

1997
56 Citations (Scopus)

Oxygen Sensing and Signal Transduction in Metabolic Defense Against Hypoxia: Lessons from Vertebrate Facultative Anaerobes

Hochachka, P. W., Land, S. C. & Buck, L. T., 1 Sep 1997, In : Comparative Biochemistry and Physiology - A Physiology. 118, 1, p. 23-29 7 p.

Research output: Contribution to journalReview article

Vertebrates
Signal Transduction
Oxygen
Down-Regulation
Adenosine Triphosphate
1998
11 Citations (Scopus)

Lens intermediate filament proteins.

Sandilands, A., Masaki, S. & Quinlan, R. A., 1 Jan 1998, In : Sub-cellular biochemistry. 31, p. 291-318 28 p.

Research output: Contribution to journalReview article

215 Citations (Scopus)

MCM proteins: evolution, properties, and role in DNA replication

Kearsey, SE. & Labib, K., 16 Jun 1998, In : Biochimica et Biophysica Acta-Gene Structure and Expression. 1398, 2, p. 113-136 24 p.

Research output: Contribution to journalReview article

44 Citations (Scopus)

Regulation of cytosolic enzymes in primary metabolism by reversible protein phosphorylation

MacKintosh, C., 1998, In : Current Opinion in Plant Biology. 1, 3, p. 224-229 6 p.

Research output: Contribution to journalReview article

1182 Citations (Scopus)

The AMP-activated/SNF1 protein kinase subfamily: Metabolic sensors of the eukaryotic cell?

Hardie, D. G., Carling, D. & Carlson, M., Jul 1998, In : Annual Review of Biochemistry. 67, p. 821-855 35 p.

Research output: Contribution to journalReview article

1999
124 Citations (Scopus)

General anaesthetic action at transmitter-gated inhibitory amino acid receptors

Belelli, D., Pistis, M., Peters, J. A. & Lambert, J. J., 1 Dec 1999, In : Trends in Pharmacological Sciences. 20, 12, p. 496-502 7 p.

Research output: Contribution to journalReview article

Amino Acid Receptors
General Anesthetics
Anesthetics
Transmitters
GABA Receptors
170 Citations (Scopus)

Resistance to oomycetes: a general role for the hypersensitive response?

Kamoun, S., Huitema, E. & Vleeshouwers, V. G. A. A., May 1999, In : Trends in Plant Science. 4, 5, p. 196-200 5 p.

Research output: Contribution to journalReview article

2000
85 Citations (Scopus)

A clock-work somite

Dale, K. J. & Pourquié, O., 24 Jan 2000, In : BioEssays. 22, 1, p. 72-83 12 p.

Research output: Contribution to journalReview article

Somites
Periodicity
Clocks
Vertebrates
Homeobox Genes
448 Citations (Scopus)

The Tat protein export pathway

Berks, B. C., Sargent, F. & Palmer, T., Jan 2000, In : Molecular Microbiology. 35, 2, p. 260-274 15 p.

Research output: Contribution to journalReview article

2001
41 Citations (Scopus)

Fc receptors and immunity to parasites

Pleass, R. J. & Woof, J. M., 1 Nov 2001, In : Trends in Parasitology. 17, 11, p. 545-551 7 p.

Research output: Contribution to journalReview article

Fc Receptors
Immunity
Parasites
Immune Evasion
Antigen Presentation
118 Citations (Scopus)

Is the MCM2-7 complex the eukaryotic DNA replication fork helicase?

Labib, K. & Diffley, JF., Feb 2001, In : Current Opinion in Genetics & Development. 11, 1, p. 64-70 7 p.

Research output: Contribution to journalReview article

127 Citations (Scopus)

Modulation of native and recombinant GABAA receptors by endogenous and synthetic neuroactive steroids

Lambert, J. J., Belelli, D., Harney, S. C., Peters, J. A. & Frenguelli, B. G., Nov 2001, In : Brain Research Reviews. 37, 1-3, p. 68-80 13 p.

Research output: Contribution to journalReview article

GABA-A Receptors
Pregnanes
Steroids
Neurotransmitter Agents
Central Nervous System
65 Citations (Scopus)

Regulation of plant NR activity by reversible phosphorylation, 14-3-3 proteins and proteolysis

MacKintosh, C. & Meek, S. E. M., 2001, In : Cellular and Molecular Life Sciences. 58, 2, p. 205-214 10 p.

Research output: Contribution to journalReview article

2002
51 Citations (Scopus)

A comment on the colour-colour diagrams of low-mass X-ray binaries

Gierliński, M. & Done, C., 21 Apr 2002, In : Monthly Notices of the Royal Astronomical Society. 331, 4, p. L47-L50 4 p.

Research output: Contribution to journalReview article

Open Access
color-color diagram
diagram
atolls
atoll
x rays
80 Citations (Scopus)

Assembly of membrane-bound respiratory complexes by the Tat protein-transport system

Sargent, F., Berks, B. C. & Palmer, T., Aug 2002, In : Archives of Microbiology. 178, 2, p. 77-84 8 p.

Research output: Contribution to journalReview article

26 Citations (Scopus)

Complex regulation of thyroid hormone action: multiple opportunities for pharmacological intervention

Shi, Y-B., Ritchie, J. W. A. & Taylor, P. M., 2002, In : Pharmacology & Therapeutics. 94, 3, p. 235-251 17 p.

Research output: Contribution to journalReview article

37 Citations (Scopus)

Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly

Zhang, C., Golderg, M. W., Moore, W. J., Allen, T. D. & Clarke, P. R., 1 Nov 2002, In : European Journal of Cell Biology. 81, 11, p. 623-633 11 p.

Research output: Contribution to journalReview article

Nuclear Pore
Nuclear Envelope
Chromatin
Guanosine Triphosphate
Membranes
88 Citations (Scopus)

Peroxisome proliferator-activated receptor agonists, hyperlipidaemia, and atherosclerosis

Vosper, H., Khoudoli, G. A., Graham, T. L. & Palmer, C. N. A., 27 Aug 2002, In : Pharmacology and Therapeutics. 95, 1, p. 47-62 16 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Hyperlipidemias
Atherosclerosis
Pharmaceutical Preparations
Lipids

Steps leading to the initiation of replication: Where we are and where we may be going

Woodward, A., Li, A. & Blow, J. J., Jun 2002, In : Chemtracts. 15, 6, p. 289-312 24 p.

Research output: Contribution to journalReview article

2003
16 Citations (Scopus)

Altered calcium regulation in freshly isolated aortic smooth muscle cells from bile duct-ligated rats: Role of nitric oxide

Atucha, N. M., Iyu, D., De Rycker, M., Soler, A. & García-Estañ, J., Feb 2003, In : Cell Calcium. 33, 2, p. 129-135 7 p.

Research output: Contribution to journalReview article

Bile Ducts
Smooth Muscle Myocytes
Nitric Oxide
Calcium
Ligation
56 Citations (Scopus)

Metastases to the breast revisited: radiological-histopathological correlation

Bartella, L., Kaye, J., Perry, N. M., Malhotra, A., Evans, D., Ryan, D., Wells, C. & Vinnicombe, S. J., Jul 2003, In : Clinical Radiology. 58, 7, p. 524-31 8 p.

Research output: Contribution to journalReview article

Breast
Neoplasm Metastasis
Breast Neoplasms
Unnecessary Procedures
Neoplasms
386 Citations (Scopus)

Neurosteroid modulation of GABAA receptors

Lambert, J. J., Belelli, D., Peden, D. R., Vardy, A. W. & Peters, J. A., Sep 2003, In : Progress in neurobiology. 71, 1, p. 67-80 14 p.

Research output: Contribution to journalReview article

GABA-A Receptors
Neurotransmitter Agents
Steroids
GABA Receptors
Pregnanes
2004
24 Citations (Scopus)

6-phosphogluconate dehydrogenase: A target for drugs in African trypanosomes

Hanau, S., Rinaldi, E., Dallocchio, F., Gilbert, I. H., Dardonville, C., Adams, M. J., Gover, S. & Barrett, M. P., Oct 2004, In : Current Topics in Medicinal Chemistry. 11, 19, p. 2639-2650 12 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Affinity methods for phosphorylation-dependent interactions.

Moorhead, G. & MacKintosh, C., 1 Jan 2004, In : Methods in Molecular Biology (Clifton, N.J.). 261, p. 469-478 10 p.

Research output: Contribution to journalReview article

Phosphorylation
Proteins
Phosphopeptides
Phosphoprotein Phosphatases
Phosphoproteins
381 Citations (Scopus)

Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes

Mackintosh, C., 15 Jul 2004, In : Biochemical Journal. 381, p. 329-342 14 p.

Research output: Contribution to journalReview article

53 Citations (Scopus)

Linking sequence to phenotype in Phytophthora-plant interactions

Huitema, E., Bos, J. I. B., Tian, M., Win, J., Waugh, M. E. & Kamoun, S., Apr 2004, In : Trends in Microbiology. 12, 4, p. 193-200 8 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Molecular genetics methods for human intermediate filament diseases

Smith, F. J. D., Sandilands, A. & McLean, W. H. I., 1 Dec 2004, In : Methods in Cell Biology. 2004, 78, p. 131-161 31 p.

Research output: Contribution to journalReview article

184 Citations (Scopus)

Radiative processes, spectral states and variability of black-hole binaries

Zdziarski, A. A. & Gierliński, M., 1 May 2004, In : Progress of Theoretical Physics Supplements. 155, p. 99-119 21 p.

Research output: Contribution to journalReview article

scattering
synchrotrons
electrons
x rays
hysteresis
180 Citations (Scopus)

The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules

Watts, C., Jul 2004, In : Nature Immunology. 5, 7, p. 685-692 8 p.

Research output: Contribution to journalReview article

20 Citations (Scopus)

The intermediate filament systems in the eye lens

Der Perng, M., Sandilands, A., Kuszak, J., Dahm, R., Wegener, A., Prescott, A. R. & Quinlan, R. A., 1 Dec 2004, In : Methods in Cell Biology. 2004, 78, p. 597-624 28 p.

Research output: Contribution to journalReview article

2005
89 Citations (Scopus)

Cracking the egg: increased complexity in the zona pellucida

Conner, S. J., Lefièvre, L., Hughes, D. C. & Barratt, C. L. R., 1 May 2005, In : Human Reproduction. 20, 5, p. 1148-1152 5 p.

Research output: Contribution to journalReview article

Zona Pellucida
Ovum
Herpes Zoster
Fertilization
Proteins
25 Citations (Scopus)

Tipping the scales toward more effective antibodies

Woof, J. M., 2 Dec 2005, In : Science. 310, 5753, p. 1442-1443 2 p.

Research output: Contribution to journalReview article

2006
1 Citation (Scopus)

A rnyxobacterial S-motility protein dances with poles

Huitema, E. & Viollier, P. H., Jun 2006, In : Trends in Microbiology. 14, 6, p. 247-248 2 p.

Research output: Contribution to journalReview article

Chromatography: From colour writing to separation science

MacKintosh, C., 1 Dec 2006, In : Biochemist. 28, 6, p. 39-42 4 p.

Research output: Contribution to journalReview article

38 Citations (Scopus)

Harvesting the potential of induced biological diversity

Waugh, R., Leader, D. J., McCallum, N. & Caldwell, D., 1 Feb 2006, In : Trends in Plant Science. 11, 2, p. 71-79 9 p.

Research output: Contribution to journalReview article

mutagenesis
biodiversity
crops
plant genetics
molecular cloning
127 Citations (Scopus)

Neuroactive steroids and inhibitory neurotransmission: Mechanisms of action and physiological relevance

Belelli, D., Herd, M. B., Mitchell, E. A., Peden, D. R., Vardy, A. W., Gentet, L. & Lambert, J. J., 27 Mar 2006, In : Neuroscience. 138, 3, p. 821-829 9 p.

Research output: Contribution to journalReview article

Synaptic Transmission
Neurotransmitter Agents
GABA-A Receptors
Steroids
Brain
2007
90 Citations (Scopus)

A key role for the GINS complex at DNA replication forks

Labib, K. & Gambus, A., Jun 2007, In : Trends in Cell Biology. 17, 6, p. 271-278 8 p.

Research output: Contribution to journalReview article

1192 Citations (Scopus)

A unified classification system for eukaryotic transposable elements

Wicker, T., Sabot, F., Hua-Van, A., Bennetzen, J. L., Capy, P., Chalhoub, B., Flavell, A., Leroy, P., Morgante, M., Panaud, O., Paux, E., SanMiguel, P. & Schulman, A. H., Dec 2007, In : Nature Reviews Genetics. 8, 12, p. 973-982 10 p.

Research output: Contribution to journalReview article

76 Citations (Scopus)

Look on the positive side! The orientation, identification and bioenergetics of 'Archaeal' membrane-bound nitrate reductases

Martinez-Espinosa, R. M., Dridge, E. J., Bonete, M. J., Butt, J. N., Butler, C. S., Sargent, F. & Richardson, D. J., Nov 2007, In : FEMS Microbiology Letters. 276, 2, p. 129-139 11 p.

Research output: Contribution to journalReview article

25 Citations (Scopus)

Molecular barley breeding

Rae, S. J., Macaulay, M., Ramsay, L., Leigh, F., Matthews, D., O'Sullivan, D. M., Donini, P., Morris, P. C., Powell, W., Marshall, D. F., Waugh, R. & Thomas, W. T. B., 1 Dec 2007, In : Euphytica. 158, 3, p. 295-303 9 p.

Research output: Contribution to journalReview article

DNA Shuffling
Hordeum
Gene Pool
barley
marker-assisted selection
97 Citations (Scopus)

Replication fork barriers: pausing for a break or stalling for time?

Labib, K. & Hodgson, B., Apr 2007, In : EMBO Reports. 8, 4, p. 346-353 8 p.

Research output: Contribution to journalReview article