School of Life Sciences

  • United Kingdom

Research Output 1968 2020

Filter
Review article
2012
74 Citations (Scopus)

Chromatin as an oxygen sensor and active player in the hypoxia response

Melvin, A. & Rocha, S., Jan 2012, In : Cellular Signalling. 24, 1, p. 35-43 9 p.

Research output: Contribution to journalReview article

19 Citations (Scopus)

Epigenetic mechanisms, nuclear architecture and the control of gene expression in trypanosomes

Alsford, S., duBois, K., Horn, D. & Field, M. C., 29 May 2012, In : Expert reviews in molecular medicine. 14, 20 p., ARTN e13.

Research output: Contribution to journalReview article

16 Citations (Scopus)

Human papillomavirus-16 E5 protein: oncogenic role and therapeutic value

Ganguly, N., 2012, In : Cellular Oncology. 35, 2, p. 67-76 10 p.

Research output: Contribution to journalReview article

49 Citations (Scopus)

Protein turnover and plant RNA and phosphorus requirements in relation to nitrogen fixation

Raven, J. A., Jun 2012, In : Plant Science. 188, p. 25-35 11 p.

Research output: Contribution to journalReview article

78 Citations (Scopus)

The endosome-lysosome pathway and information generation in the immune system

Watts, C., Jan 2012, In : Biochimica et Biophysica Acta. Proteins and Proteomics. 1824, 1, p. 14-21 8 p.

Research output: Contribution to journalReview article

47 Citations (Scopus)

The hows and whys of aerobic H-2 metabolism

Parkin, A. & Sargent, F., Apr 2012, In : Current Opinion in Chemical Biology. 16, 1-2, p. 26-34 9 p.

Research output: Contribution to journalReview article

64 Citations (Scopus)

When the PilZ don't work: effectors for cyclic di-GMP action in bacteria

Ryan, R. P., Tolker-Nielsen, T. & Dow, J. M., 1 May 2012, In : Trends in Microbiology. 20, 5, p. 235-242 8 p.

Research output: Contribution to journalReview article

2011
16 Citations (Scopus)

Advances in bacterial transcriptome and transposon insertion-site profiling using second-generation sequencing

Febrer, M., McLay, K., Caccamo, M., Twomey, K. B. & Ryan, R. . P., 1 Nov 2011, In : Trends in Biotechnology. 29, 11, p. 586-594 9 p.

Research output: Contribution to journalReview article

111 Citations (Scopus)

AMP-activated protein kinase: also regulated by ADP?

Hardie, D. G., Carling, D. & Gamblin, S. J., Sep 2011, In : Trends in Biochemical Sciences. 36, 9, p. 470-477 8 p.

Research output: Contribution to journalReview article

849 Citations (Scopus)

AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

Hardie, D. G., 15 Sep 2011, In : Genes & Development. 25, 18, p. 1895-1908 14 p.

Research output: Contribution to journalReview article

147 Citations (Scopus)

Analysis of plant diversity with retrotransposon-based molecular markers

Kalendar, R., Flavell, A. J., Ellis, T. H. N., Sjakste, T., Moisy, C. & Schulman, A. H., Apr 2011, In : Heredity. 106, 4, p. 520-530 11 p.

Research output: Contribution to journalReview article

93 Citations (Scopus)

Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria

Ryan, R. P. & Dow, J. M., 1 Mar 2011, In : Trends in Microbiology. 19, 3, p. 145-152 8 p.

Research output: Contribution to journalReview article

46 Citations (Scopus)

Emerging role of surface plasmon resonance in fragment-based drug discovery

Navratilova, I. & Hopkins, A. L., Oct 2011, In : Future Medicinal Chemistry. 3, 14, p. 1809-1820 12 p.

Research output: Contribution to journalReview article

14 Citations (Scopus)
27 Citations (Scopus)

Finding New Hits in Neglected Disease Projects: Target or Phenotypic Based Screening?

Gilbert, I. H., Leroy, D. & Frearson, J. A., May 2011, In : Current Topics in Medicinal Chemistry. 11, 10, p. 1284-1291 8 p.

Research output: Contribution to journalReview article

30 Citations (Scopus)

Homeostasis in the vertebrate lens: mechanisms of solute exchange

Dahm, R., van Marle, J., Quinlan, R. A., Prescott, A. R. & Vrensen, G. F. J. M., 27 Apr 2011, In : Philosophical Transactions of the Royal Society B - Biological Sciences. 366, 1568, p. 1265-1277 13 p.

Research output: Contribution to journalReview article

179 Citations (Scopus)
1800 Downloads (Pure)

Interventions for preventing oral mucositis for patients with cancer receiving treatment

Worthington, H., Clarkson, J. E., Bryan, G., Furness, S., Glenny, A. M., Littlewood, A., McCabe, M. G., Meyer, S. & Khalid, T., 13 Apr 2011, In : Cochrane Database of Systematic Reviews. 2011, 4, 276 p., CD000978.

Research output: Contribution to journalReview article

Open Access
File
15 Citations (Scopus)
64 Citations (Scopus)

Mechanisms for ATP-dependent chromatin remodelling: the means to the end

Flaus, A. & Owen-Hughes, T., Oct 2011, In : FEBS Journal. 278, 19, p. 3579-3595 17 p.

Research output: Contribution to journalReview article

32 Citations (Scopus)

Mechanisms of RNA catalysis

Lilley, D. M. J., 27 Oct 2011, In : Philosophical Transactions of the Royal Society B - Biological Sciences. 366, 1580, p. 2910-2917 8 p.

Research output: Contribution to journalReview article

25 Citations (Scopus)

Methylglyoxal metabolism in trypanosomes and leishmania

Wyllie, S. & Fairlamb, A. H., May 2011, In : Seminars in Cell & Developmental Biology. 22, 3, p. 271-277 7 p.

Research output: Contribution to journalReview article

65 Citations (Scopus)

Minimum information about a bioactive entity (MIABE)

Orchard, S., Al-Lazikani, B., Bryant, S., Clark, D., Calder, E., Dix, I., Engkvist, O., Forster, M., Gaulton, A., Gilson, M., Glen, R., Grigorov, M., Hammond-Kosack, K., Harland, L., Hopkins, A., Larminie, C., Lynch, N., Mann, R. K., Murray-Rust, P., Lo Piparo, E. & 6 others, Southan, C., Steinbeck, C., Wishart, D., Hermjakob, H., Overington, J. & Thornton, J., Sep 2011, In : Nature Reviews Drug Discovery. 10, 9, p. 661-669 9 p.

Research output: Contribution to journalReview article

13 Citations (Scopus)

Nuclear organization and transcriptional dynamics in Dictyostelium

Stevense, M., Chubb, J. R. & Muramoto, T., May 2011, In : Development, Growth & Differentiation. 53, 4, p. 576-586 11 p.

Research output: Contribution to journalReview article

184 Citations (Scopus)

Pathogenomics of Xanthomonas: understanding bacterium-plant interactions

Ryan, R. P., Vorhölter, F-J., Potnis, N., Jones, J. B., Van Sluys, M-A., Bogdanove, A. J. & Dow, J. M., 1 May 2011, In : Nature Reviews Microbiology. 9, 5, p. 344-355 12 p.

Research output: Contribution to journalReview article

14 Citations (Scopus)

Rapid Analysis of Pharmacology for Infectious Diseases

Hopkins, A. L., Bickerton, G. R., Carruthers, I. M., Boyer, S. K., Rubin, H. & Overington, J. P., May 2011, In : Current Topics in Medicinal Chemistry. 11, 10, p. 1292-1300 9 p.

Research output: Contribution to journalReview article

375 Citations (Scopus)

Root elongation, water stress, and mechanical impedance: a review of limiting stresses and beneficial root tip traits

Bengough, A. G., McKenzie, B. M., Hallett, P. D. & Valentine, T. A., Jan 2011, In : Journal of Experimental Botany. 62, 1, p. 59-68 10 p.

Research output: Contribution to journalReview article

53 Citations (Scopus)

Snf2-family proteins: chromatin remodellers for any occasion

Ryan, D. P. & Owen-Hughes, T., Oct 2011, In : Current Opinion in Chemical Biology. 15, 5, p. 649-656 8 p.

Research output: Contribution to journalReview article

51 Citations (Scopus)

Sphingolipids: agents provocateurs in the pathogenesis of insulin resistance

Lipina, C. & Hundal, H. S., Jul 2011, In : Diabetologia. 54, 7, p. 1596-1607 12 p.

Research output: Contribution to journalReview article

26 Citations (Scopus)

Synthetic glycosylphosphatidylinositol (GPI) anchors: how these complex molecules have been made

Nikolaev, A. V. & Al-Maharik, N., 2011, In : Natural Product Reports. 28, 5, p. 970-1020 51 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Synthetic Neoglycoconjugates of Cell-Surface Phosphoglycans of Leishmania as Potential Anti-parasite Carbohydrate Vaccines

Nikolaev, A. V. & Sizova, O. V., Jul 2011, In : Biochemistry-Moscow. 76, 7, p. 761-773 13 p.

Research output: Contribution to journalReview article

56 Citations (Scopus)
32 Citations (Scopus)

The capture of phosphoproteins by 14-3-3 proteins mediates actions of insulin

Chen, S., Synowsky, S., Tinti, M. & MacKintosh, C., Nov 2011, In : Trends in Endocrinology and Metabolism. 22, 11, p. 429-436 8 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Transcriptome sequencing of an ecologically important graminivorous sawfly: a resource for marker development

Cook, N., Aziz, N., Hedley, P. E., Morris, J., Milne, L., Karley, A. J., Hubbard, S. F. & Russell, J. R., Oct 2011, In : Conservation Genetics Resources. 3, 4, p. 789-795 7 p.

Research output: Contribution to journalReview article

31 Citations (Scopus)
117 Downloads (Pure)

Virtual screening strategies in drug design – methods and applications

Bielska, E., Lucas, X., Czerwoniec, A., Kasprzak, J. M., Kaminska, K. H. & Bujnicki, J. M., 2011, In : BioTechnologia. 92, 3, p. 249-264 16 p.

Research output: Contribution to journalReview article

Open Access
File
Drug Design
Drug Discovery
Ligands
screening
drugs
2010
52 Citations (Scopus)

Assessing brain free fraction in early drug discovery

Read, K. D. & Braggio, S., Mar 2010, In : Expert Opinion on Drug Metabolism & Toxicology. 6, 3, p. 337-344 8 p.

Research output: Contribution to journalReview article

58 Citations (Scopus)

Bursts and pulses: insights from single cell studies into transcriptional mechanisms

Chubb, J. R. & Liverpool, T. B., Oct 2010, In : Current Opinion in Genetics & Development. 20, 5, p. 478-484 7 p.

Research output: Contribution to journalReview article

59 Citations (Scopus)

Dictyostelium finds new roles to model

Williams, J. G., Jul 2010, In : Genetics. 185, 3, p. 717-726 10 p.

Research output: Contribution to journalReview article

27 Citations (Scopus)

Drug discovery in academia: the third way?

Frearson, J. & Wyatt, P., Oct 2010, In : Expert Opinion on Drug Discovery. 5, 10, p. 909-919 11 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Exploiting induced variation to dissect quantitative traits in barley

Druka, A., Franckowiak, J., Lundqvist, U., Bonar, N., Alexander, J., Guzy-Wrobelska, J., Ramsay, L., Druka, I., Grant, I., Macaulay, M., Vendramin, V., Shahinnia, F., Radovic, S., Houston, K., Harrap, D., Cardle, L., Marshall, D., Morgante, M., Stein, N. & Waugh, R., 1 Apr 2010, In : Biochemical Society Transactions. 38, 2, p. 683-688 6 p.

Research output: Contribution to journalReview article

Hordeum
Genes
Quantitative Trait Loci
Cloning
Organism Cloning
38 Citations (Scopus)

Insect endosymbionts: manipulators of insect herbivore trophic interactions?

Clark, E. L., Karley, A. J. & Hubbard, S. F., Aug 2010, In : Protoplasma. 244, 1-4, p. 25-51 27 p.

Research output: Contribution to journalReview article

77 Citations (Scopus)

Kinetochore-microtubule interactions: steps towards bi-orientation

Tanaka, T. U., 15 Dec 2010, In : EMBO Journal. 29, 24, p. 4070-4082 13 p.

Research output: Contribution to journalReview article

89 Citations (Scopus)

Molecular mechanisms underlying the control of antigenic variation in African trypanosomes

Horn, D. & McCulloch, R., Dec 2010, In : Current Opinion in Microbiology. 13, 6, p. 700-705 6 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)

Myc regulation of mRNA cap methylation

Cowling, V. H. & Cole, M. D., Jun 2010, In : Genes and Cancer. 1, 6, p. 576-579 4 p.

Research output: Contribution to journalReview article

Methylation
myc Genes
Messenger RNA
RNA Polymerase II
Genes
6 Citations (Scopus)

Myc up-regulates formation of the mRNA methyl cap

Cowling, V. H., Dec 2010, In : Biochemical Society Transactions. 38, p. 1598-1601 4 p.

Research output: Contribution to journalReview article

77 Citations (Scopus)

Post-translational modification by SUMO

Hannoun, Z., Greenhough, S., Jaffray, E., Hay, R. T. & Hay, D. C., 30 Dec 2010, In : Toxicology. 278, 3, p. 288-293 6 p.

Research output: Contribution to journalReview article

46 Citations (Scopus)

Recent developments in effector biology of filamentous plant pathogens

Oliva, R., Win, J., Raffaele, S., Boutemy, L., Bozkurt, T. O., Chaparro-Garcia, A., Segretin, M. E., Stam, R., Schornack, S., Cano, L. M., van Damme, M., Huitema, E., Thines, M., Banfield, M. J. & Kamoun, S., Jun 2010, In : Cellular Microbiology. 12, 6, p. 705-715 11 p.

Research output: Contribution to journalReview article

71 Citations (Scopus)

Regulation of mRNA cap methylation

Cowling, V. H., 15 Jan 2010, In : Biochemical Journal. 425, p. 295-302 8 p.

Research output: Contribution to journalReview article

241 Citations (Scopus)

The complex extracellular biology of streptomyces

Chater, K. F., Biro, S., Lee, K. J., Palmer, T. & Schrempf, H., Mar 2010, In : FEMS Microbiology Reviews. 34, 2, p. 171-198 28 p.

Research output: Contribution to journalReview article

516 Citations (Scopus)

The Nucleolus under Stress

Boulon, S., Westman, B. J., Hutten, S., Boisvert, F-M. & Lamond, A. I., 22 Oct 2010, In : Molecular Cell. 40, 2, p. 216-227 12 p.

Research output: Contribution to journalReview article

53 Citations (Scopus)

The segmentation clock mechanism moves up a notch

Gibb, S., Maroto, M. & Dale, J. K., Oct 2010, In : Trends in Cell Biology. 20, 10, p. 593-600 8 p.

Research output: Contribution to journalReview article