School of Life Sciences

  • United Kingdom

Research Output 1968 2020

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Review article
2010
241 Citations (Scopus)

The complex extracellular biology of streptomyces

Chater, K. F., Biro, S., Lee, K. J., Palmer, T. & Schrempf, H., Mar 2010, In : FEMS Microbiology Reviews. 34, 2, p. 171-198 28 p.

Research output: Contribution to journalReview article

518 Citations (Scopus)

The Nucleolus under Stress

Boulon, S., Westman, B. J., Hutten, S., Boisvert, F-M. & Lamond, A. I., 22 Oct 2010, In : Molecular Cell. 40, 2, p. 216-227 12 p.

Research output: Contribution to journalReview article

53 Citations (Scopus)

The segmentation clock mechanism moves up a notch

Gibb, S., Maroto, M. & Dale, J. K., Oct 2010, In : Trends in Cell Biology. 20, 10, p. 593-600 8 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)

The tetrahydrobiopterin pathway and pain

Naylor, A. M., Pojasek, K. R., Hopkins, A. L. & Blagg, J., Jan 2010, In : Current Opinion in Investigational Drugs. 11, 1, p. 19-30 12 p.

Research output: Contribution to journalReview article

292 Citations (Scopus)

Through the "gatekeeper door": exploiting the active kinase conformation

Zuccotto, F., Ardini, E., Casale, E. & Angiolini, M., 8 Apr 2010, In : Journal of Medicinal Chemistry. 53, 7, p. 2681-2694 14 p.

Research output: Contribution to journalReview article

102 Citations (Scopus)

TLR signalling regulated antigen presentation in dendritic cells

Watts, C., West, M. A. & Zaru, R., Feb 2010, In : Current Opinion in Immunology. 22, 1, p. 124-130 7 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)

Towards an understanding on how RxLR-effector proteins are translocated from oomycetes into host cells

Grouffaud, S., Whisson, S. C., Birch, P. R. J. & West, P. V., 2010, In : Fungal Biology Reviews. 24, 1-2, p. 27-36

Research output: Contribution to journalReview article

Oomycetes
Parasites
Proteins
Fungi
Phytophthora infestans
162 Citations (Scopus)

Visualization of image data from cells to organisms

Walter, T., Shattuck, D. W., Baldock, R., Bastin, M. E., Carpenter, A. E., Duce, S., Ellenberg, J., Fraser, A., Hamilton, N., Pieper, S., Ragan, M. A., Schneider, J. E., Tomancak, P. & Hériché, J. K., 1 Mar 2010, In : Nature Methods. 7, 3, p. S26-S41 16 p.

Research output: Contribution to journalReview article

Visualization
Throughput
Imaging techniques
Proteins
Technology
50 Citations (Scopus)

Visualization of multiple alignments, phylogenies and gene family evolution

Procter, J. B., Thompson, J., Letunic, I., Creevey, C., Jossinet, F. & Barton, G. J., 1 Mar 2010, In : Nature Methods. 7, 3, p. S16-S25 10 p.

Research output: Contribution to journalReview article

2009
190 Citations (Scopus)

Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling

Hundal, H. S. & Taylor, P. M., Apr 2009, In : American Journal of Physiology, Endocrinology and Metabolism. 296, 4, p. E603-E613 11 p.

Research output: Contribution to journalReview article

84 Citations (Scopus)

AMP-activated protein kinase: a sensor of glycogen as well as AMP and ATP?

McBride, A. & Hardie, D. G., May 2009, In : Acta Physiologica. 196, 1, p. 99-113 15 p.

Research output: Contribution to journalReview article

173 Citations (Scopus)

An additional role for SUMO in ubiquitin-mediated proteolysis

Geoffroy, M-C. & Hay, R. T., Aug 2009, In : Nature Reviews Molecular Cell Biology. 10, 8, p. 564-568 5 p.

Research output: Contribution to journalReview article

67 Citations (Scopus)

A pivotal role for the response regulator DegU in controlling multicellular behaviour

Murray, E. J., Kiley, T. B. & Stanley-Wall, N. R., Jan 2009, In : Microbiology. 155, p. 18 8 p.

Research output: Contribution to journalReview article

76 Citations (Scopus)

Bioimage informatics for experimental biology

Swedlow, J. R., Goldberg, I. G., Eliceiri, K. W. & OME Consortium, 2009, In : Annual Review of Biophysics. 38, p. 327-346 20 p.

Research output: Contribution to journalReview article

55 Citations (Scopus)

Deep rooting and drought screening of cereal crops: a novel field-based method and its application

McKenzie, B. M., Bengough, A. G., Hallett, P. D., Thomas, W. T. B., Forster, B. & McNicol, J. W., 26 Jun 2009, In : Field Crops Research. 112, 2-3, p. 165-171 7 p.

Research output: Contribution to journalReview article

79 Citations (Scopus)

Diverse regulatory roles for lysosomal proteases in the immune response

Colbert, J. D., Matthews, S. P., Miller, G. & Watts, C., Nov 2009, In : European Journal of Immunology. 39, 11, p. 2955-2965 11 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

DNA breaks as triggers for antigenic variation in African trypanosomes

Alsford, S., Horn, D. & Glover, L., 2009, In : Genome Biology. 10, 6, 4 p., ARTN 223.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Imaging cell signalling and movement in development

Chuai, M., Dormann, D. & Weijer, C. J., Oct 2009, In : Seminars in Cell & Developmental Biology. 20, 8, p. 947-955 9 p.

Research output: Contribution to journalReview article

127 Citations (Scopus)

Lipoprotein biogenesis in Gram-positive bacteria: knowing when to hold 'em, knowing when to fold 'em

Hutchings, M. I., Palmer, T., Harrington, D. J. & Sutcliffe, I. C., Jan 2009, In : Trends in Microbiology. 17, 1, p. 13-21 9 p.

Research output: Contribution to journalReview article

35 Citations (Scopus)
255 Downloads (Pure)

Open source bioimage informatics for cell biology

Swedlow, J. R. & Eliceiri, K. W., Nov 2009, In : Trends in Cell Biology. 19, 11, p. 656-660 5 p.

Research output: Contribution to journalReview article

File
23 Citations (Scopus)

Protein S-acylation in plants (Review)

Hemsley, P. A., 2009, In : Molecular Membrane Biology. 26, 1-2, p. 114-125 12 p.

Research output: Contribution to journalReview article

Acylation
Protein S
Membranes
Membrane Proteins
Lipoylation
24 Citations (Scopus)

Regulation of cell migration during chick gastrulation

Chuai, M. & Weijer, C. J., Aug 2009, In : Current Opinion in Genetics & Development. 19, 4, p. 343-349 7 p.

Research output: Contribution to journalReview article

111 Citations (Scopus)

Sirtuin/Sir2 phylogeny, evolutionary considerations and structural conservation

Greiss, S. & Gartner, A., Nov 2009, In : Molecules and Cells. 28, 5, p. 407-415 9 p.

Research output: Contribution to journalReview article

159 Citations (Scopus)

Stem cells, signals and vertebrate body axis extension

Wilson, V., Olivera-Martinez, I. & Storey, K. G., 15 May 2009, In : Development. 136, 10, p. 1591-1604 14 p.

Research output: Contribution to journalReview article

39 Citations (Scopus)

Structure-based ligand design and the promise held for antiprotozoan drug discovery

Hunter, W. N., 1 May 2009, In : Journal of Biological Chemistry. 284, 18, p. 11749-11753 5 p.

Research output: Contribution to journalReview article

103 Citations (Scopus)

Ten things to know about oomycete effectors

Schornack, S., Huitema, E., Cano, L. M., Bozkurt, T. O., Oliva, R., van Damme, M., Schwizer, S., Raffaele, S., Chaparro-Garcia, A., Farrer, R., Segretin, M. E., Bos, J. I. B., Haas, B. J., Zody, M. C., Nusbaum, C., Win, J., Thines, M. & Kamoun, S., Nov 2009, In : Molecular Plant Pathology. 10, 6, p. 795-803 9 p.

Research output: Contribution to journalReview article

103 Citations (Scopus)

The emergence of whole genome association scans in barley

Waugh, R., Jannink, J. L., Muehlbauer, G. J. & Ramsay, L., Apr 2009, In : Current Opinion in Plant Biology. 12, 2, p. 218-222 5 p.

Research output: Contribution to journalReview article

barley
genome
geneticists
linkage disequilibrium
plant breeding
118 Citations (Scopus)

The International Barley Sequencing Consortium - At the threshold of efficient access to the barley genome

Schulte, D., Close, T. J., Graner, A., Langridge, P., Matsumoto, T., Muehlbauer, G., Sato, K., Schulman, A. H., Waugh, R., Wise, R. P. & Stein, N., 1 Jan 2009, In : Plant Physiology. 149, 1, p. 142-147 6 p.

Research output: Contribution to journalReview article

281 Citations (Scopus)

The versatility and adaptation of bacteria from the genus Stenotrophomonas

Ryan, R. P., Monchy, S., Cardinale, M., Taghavi, S., Crossman, L., Avison, M. B., Berg, G., van der Lelie, D. & Dow, J. M., 1 Jan 2009, In : Nature Reviews Microbiology. 7, 7, p. 514-525 12 p.

Research output: Contribution to journalReview article

87 Citations (Scopus)

The zig-zag-zig in oomycete-plant interactions

Hein, I., Gilroy, E. M., Armstrong, M. R. & Birch, P. R. J., Jul 2009, In : Molecular Plant Pathology. 10, 4, p. 547-562 16 p.

Research output: Contribution to journalReview article

61 Citations (Scopus)

Towards understanding the virulence functions of RXLR effectors of the oomycete plant pathogen Phytophthora infestans

Birch, P. R. J., Armstrong, M., Bos, J., Boevink, P., Gilroy, E. M., Taylor, R. M., Wawra, S., Pritchard, L., Conti, L., Ewan, R., Whisson, S. C., van West, P., Sadanandom, A. & Kamoun, S., Mar 2009, In : Journal of Experimental Botany. 60, 4, p. 1133-1140 8 p.

Research output: Contribution to journalReview article

2008
20 Citations (Scopus)

Analysis of branched nucleic acid structure using comparative gel electrophoresis

Lilley, D. M. J., Feb 2008, In : Quarterly Reviews of Biophysics. 41, 1, p. 139 39 p.

Research output: Contribution to journalReview article

27 Citations (Scopus)

Bi-orienting chromosomes: acrobatics on the mitotic spindle

Tanaka, T. U., Dec 2008, In : Chromosoma. 117, 6, p. 521-533 13 p.

Research output: Contribution to journalReview article

56 Citations (Scopus)

Carrier erythrocyte entrapped thymidine phosphorylas etherapy for MNGIE

Moran, N. F., Bain, M. D., Muqit, M. M. K. & Bax, B. E., 26 Aug 2008, In : Neurology. 71, 9, p. 686-688 3 p.

Research output: Contribution to journalReview article

223 Citations (Scopus)

Cereal breeding takes a walk on the wild side

Feuillet, C., Langridge, P. & Waugh, R., Jan 2008, In : Trends in Genetics. 24, 1, p. 24-32 9 p.

Research output: Contribution to journalReview article

Gene Pool
Genetic Association Studies
Hordeum
Triticum
Breeding
81 Citations (Scopus)

Kinetochore-microtubule interactions: the means to the end

Tanaka, T. U. & Desai, A., Feb 2008, In : Current Opinion in Cell Biology. 20, 1, p. 53-63 11 p.

Research output: Contribution to journalReview article

337 Citations (Scopus)
183 Downloads (Pure)

Kinetoplastids: related protozoan pathogens, different diseases

Stuart, K., Brun, R., Croft, S., Fairlamb, A., Guertler, R. E., McKerrow, J., Reed, S. & Tarleton, R., 2008, In : Journal of Clinical Investigation. 118, 4, p. 1301-1310 10 p.

Research output: Contribution to journalReview article

Open Access
File
50 Citations (Scopus)

Multiple roles for protein palmitoylation in plants

Hemsley, P. A. & Grierson, C. S., Jun 2008, In : Trends in Plant Science. 13, 6, p. 295-302 8 p.

Research output: Contribution to journalReview article

acylation
proteins
guanosinetriphosphatase
cells
G-proteins
1530 Citations (Scopus)

Network pharmacology: the next paradigm in drug discovery

Hopkins, A. L., Nov 2008, In : Nature Chemical Biology. 4, 11, p. 682-690 9 p.

Research output: Contribution to journalReview article

61 Citations (Scopus)
22 Citations (Scopus)

Nuclear functions in space and time: Gene expression in a dynamic, constrained environment

Trinkle-Mulcahy, L. & Lamond, A. I., 18 Jun 2008, In : FEBS Letters. 582, 14, p. 1960-1970 11 p.

Research output: Contribution to journalReview article

109 Citations (Scopus)

Oomycete RXLR effectors: delivery, functional redundancy and durable disease resistance

Birch, P. R. J., Boevink, P. C., Gilroy, E. M., Hein, I., Pritchard, L. & Whisson, S. C., Aug 2008, In : Current Opinion in Plant Biology. 11, 4, p. 373-379 7 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Prognostic and therapeutic implications of APC mutations in colorectal cancer

Quyn, A. J., Steele, R. J. C., Carey, F. A. & Nathke, I. S., Dec 2008, In : Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 6, 6, p. 350-356 7 p.

Research output: Contribution to journalReview article

156 Citations (Scopus)

Regulation of gene expression by hypoxia

Kenneth, N. S. & Rocha, S., 15 Aug 2008, In : Biochemical Journal. 414, 1, p. 19-29 11 p.

Research output: Contribution to journalReview article

12 Citations (Scopus)

Replication forks, chromatin loops and dormant replication origins

Blow, J. J. & Ge, X. Q., 2008, In : Genome Biology. 9, 12, p. - 4 p., 244.

Research output: Contribution to journalReview article

151 Citations (Scopus)

Replication licensing and cancer -: a fatal entanglement?

Blow, J. J. & Gillespie, P. J., Oct 2008, In : Nature Reviews Cancer. 8, 10, p. 799-806 8 p.

Research output: Contribution to journalReview article

166 Citations (Scopus)

Role of AMP-activated protein kinase in the metabolic syndrome and in heart disease

Hardie, D. G., Tontonoz, P. (ed.) & Nagy, L. (ed.), 9 Jan 2008, In : FEBS Letters. 582, 1, p. 81-89 9 p.

Research output: Contribution to journalReview article

259 Citations (Scopus)

The cancer chemopreventive actions of phytochemicals derived from glucosinolates

Hayes, J. D., Kelleher, M. O. & Eggleston, I. M., May 2008, In : European Journal of Nutrition. 47, p. 73-88 16 p.

Research output: Contribution to journalReview article

90 Citations (Scopus)

Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita

Leachman, S. A., Hickerson, R. P., Hull, P. R., Smith, F. J. D., Milstone, L. M., Lane, E. B., Bale, S. J., Roop, D. R., McLean, W. H. I. & Kaspar, R. L., Sep 2008, In : Journal of Dermatological Science. 51, 3, p. 151-157 7 p.

Research output: Contribution to journalReview article