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  • 2023

    Anti-Infective Agents

    Gilbert, I., Baragana, B., Caldwell, N., Taylor, M., Forte, B., Cocco, M. & Jansen, C., 2 Nov 2023, IPC No. A61K31/519, A61P33/02, C07D487/04, Patent No. WO 2023/209336 A1, 20 Apr 2023, Priority date 26 Apr 2022, Priority No. GB202206076A

    Research output: Patent

  • 2020

    PROTEOLYSIS TARGETING CHIMERA (PROTACS) AS DEGRADERS OF SMARCA2 AND/OR SMARCA4

    Ciulli, A., Dank, C., Diers, E., Farnaby, W., Roy, M., Steurer, S. & Trainor, N., 23 Apr 2020, Patent No. WO/2020/078933, 14 Oct 2019, Priority date 16 Oct 2018, Priority No. 18200596.7

    Research output: Patent

  • Synthetic multiphase systems

    Stanley-Wall, N., Hobley, L., MacPhee, C. E., Bromley, K. M. & Morris, R. J., 25 Feb 2020, Patent No. US10570181B2, Priority date 19 Aug 2014

    Research output: Patent

  • 2019

    BIFUNCTIONAL MOLECULES FOR TARGETING RPN11

    Ciulli, A., Testa, A., Hughes, S. & Butcher, S. P., 19 Dec 2019, Patent No. WO/2019/238817, 13 Jun 2019, Priority date 13 Jun 2018

    Research output: Patent

  • BIFUNCTIONAL MOLECULES FOR TARGETING UCHL5

    Ciulli, A., Testa, A., Hughes, S. & Butcher, S. P., 19 Dec 2019, Patent No. WO/2019/238816, 13 Jun 2019

    Research output: Patent

  • BIFUNCTIONAL MOLECULES FOR TARGETING USP14

    Testa, A., Hughes, S., Butcher, S. P. & Ciulli, A., 19 Dec 2019, Patent No. WO/2019/238886, 13 Jun 2019

    Research output: Patent

  • Pharmaceutical 6,5 Heterobicyclic Ring Derivatives

    Heer, J. P., Hallside, M. S., Smalley, A. P., Llaveria Cros, J., Lallemand, B., Lowe, M. A., Li, X., Richardson, A. & Townsend, R. J., 22 Aug 2019, IPC No. A61K 31/437 2006.1, A61K 31/4375 2006.1, A61K 31/519 2006.1, A61K 31/4365 2006.1, C07D 471/04 2006.1, C07D 498/04 2006.1, C07D 513/04 2006.1, A61P 29/00 2006.1, A61P 19/00 2006.1, Patent No. WO/2019/158731, 15 Feb 2019, Priority date 16 Aug 2019, Priority No. 18157247.0

    Research output: Patent

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    25 Downloads (Pure)
  • 2018

    Fluorohydroxyproline derivatives useful in the preparation of proteolysis targeted chimeras

    Ciulli, A. & Testa, A., 22 Mar 2018, IPC No. C07D 417/12 2006.1, C07D 417/14 2006.1, C07D 495/14 2006.1, A61K 31/427 2006.1, A61K 31/551 2006.1, A61P 35/00 2006.1, A61P 29/00 2006.1, Patent No. WO/2018/051107, 14 Sept 2017, Priority date 14 Sept 2016, Priority No. 1615617.6

    Research output: Patent

  • Small molecules

    Ciulli, A., Maniaci, C., Hughes, S. & Testa, A., 18 Oct 2018, IPC No. C07D 417/14 2006.1, C07K 5/062 2006.1, A61P 35/00 2006.1, A61K 38/05 2006.1, Patent No. WO/2018/189554, 13 Apr 2018, Priority date 14 Apr 2017, Priority No. 1706042.7 / 1706043.5

    Research output: Patent

  • 2016

    DERIVATIVES OF 1-[(CYCLOPENTYL OR 2-PYRROLIDINYL)CARBONYLAMINOMETHYL]-4-(1,3-THIAZOL-5-YL) BENZENE WHICH ARE USEFUL FOR THE TREATMENT OF PROLIFERATIVE, AUTOIMMUNE OR INFLAMMATORY DISEASES

    Ciulli, A., Zengerle, M. & Chan, K. H., 22 Sept 2016, Patent No. WO/2016/146985, 14 Mar 2016, Priority date 13 Mar 2015

    Research output: Patent

  • 2015

    SONDES FONCTIONNELLES ENZYMATIQUES

    Translated title of the contribution: Enzymes functional probesShiao, E. L., Baud, M. G. J., Ciulli, A., Chan, K. H. & Zengerle, M., 4 Jun 2015, Patent No. WO/2015/079259, 28 Nov 2014, Priority date 28 Nov 2013, Priority No. 1320994.5 / 1401001.1

    Research output: Patent

  • 2014

    Imidazopyridine Derivatives as Modulators of TNF Activity

    Bentley, J. M., Brookings, D. C., Brown, J. A., Cain, T. P., Chovatia, P. T., Foley, A. M., Gallimore, E. O., Gleave, L. J., Heifetz, A., Horsley, H. T., Hutchings, M. C., Jackson, V. E., Johnson, J. A., Johnstone, C., Kroeplien, B., Comte, F. C., Leigh, D., Lowe, M. A., Madden, J., Porter, J. R., & 8 othersQuincey, J. R., Reed, L. C., Reuberson, J. T., Richardson, A., Richardson, S. E., Selby, M. D., Shaw, M. A. & Zhu, Z., 16 Jan 2014, IPC No. C07D 471/04 2006.1, C07D 471/04 2006.1, A61K 31/437 2006.1, A61P 29/00 2006.1, Patent No. WO/2014/009295, 5 Jul 2013, Priority date 13 Jul 2012, Priority No. 1212512.6

    Research output: Patent

    Open Access
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    26 Downloads (Pure)
  • 2013

    Anti-malarial agents

    Gilbert, I., Norcross, N., Baragana, B. & Porzelle, A., 17 Oct 2013, IPC No. C07D 215/52 (2006.01), A61K 31/4725 (2006.01), A61P 33/06 (2006.01) , Patent No. PCT/GB2013/050633

    Research output: Patent

  • Improved sperm function / activity

    Barratt, C. & Wyatt, P., 18 Apr 2013, IPC No. A61K31/519; A61P15/00; A61K31/52; A61K31/437; A61K45/00; A61K31/551; A61K39/395; A61K31/47, Patent No. WO2013054111 A1

    Research output: Patent

  • Method for modifying lignin biosynthesis in plants

    Halpin, C., Simpson, G. & Boerjan, W., 14 Nov 2013, IPC No. C12N 15/82 (2006.01) , Patent No. WO/2013/167902 A1

    Research output: Patent

  • Pyridinone and Pyrimidinone Derivatives as Factor XIa Inhibitors

    Courtney, S., Yarnold, C., Flanagan, S., Brace, G., Barker, J., Ichihara, O., Gadouleau, E., Richardson, A., Kondo, T., Imagawa, A., Nakatani, S., Suzuki, R. & Kouyama, S., 27 Jun 2013, IPC No. C07D 401/14 2006.1, C07D 471/04 2006.1, C07D 487/04 2006.1, A61K 31/437 2006.1, A61K 31/519 2006.1, A61P 9/00 2006.1, Patent No. WO/2013/093484, 20 Dec 2012, Priority date 21 Dec 2011, Priority No. 1122139.7

    Research output: Patent

    Open Access
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    16 Downloads (Pure)
  • 2012

    Morpholino compounds, uses and methods

    Besnard, J., Hopkins, A., Gilbert, I., Ruda, G. F. & Abecassis, K., 29 Nov 2012, Patent No. PCT/GB2012/051194, 25 May 2012

    Research output: Patent

  • 2011

    Cell migration modulating compounds

    Schor, A. M., Schor, S. L., Marquez, R. & Norman, D. G., 19 Oct 2011, Patent No. EP1917012

    Research output: Patent

  • Decontamination method

    Fomina, M. & Gadd, G., 6 Oct 2011, IPC No. G21F 9/00, Patent No. PCT/GB2011/000482

    Research output: Patent

  • Design of molecules

    Hopkins, A. & Besnard, J., 26 May 2011, Patent No. PCT/GB2010/051940

    Research output: Patent

  • 2010

    N-myristoyl transferase inhibitors

    Brand, S., Wyatt, P., Thompson, S., Smith, V., Bayliss, T., Harrison, J., Norcross, N., Cleghorn, L., Gilbert, I. & Brenk, R., 11 Mar 2010, IPC No. C07D 213/75 (2006.01), C07D 213/42 (2006.01), C07D 239/69 (2006.01), C07D 263/50 (2006.01), C07D 403/12 (2006.01), C07D 407/12 (2006.01), C07D 409/12 (2006.01), C07D 413/12 (2006.01), C07D 413/14 (2006.01), C07D 417/12 (2006.01), C07D 471/04 (2006.01), C07D 487/04 (2006.01) , Patent No. PCT/GB2009/002084

    Research output: Patent

  • 2008

    p53 activating benzoyl urea and benzoyl thiourea compounds

    Lain, S., Lane, D., Stark, M. J. R., McCarthy, A. R., Hollick, J. J. & Westwood, N. J., 13 Mar 2008, IPC No. A61K31/17, Patent No. WO2008029096

    Research output: Patent