School of Life Sciences

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• Development of a high throughput ligand screening method and structural studies of pentameric ligand gated ion channels.

  Trumper, P. (Author), Hunter, W. (Supervisor) & Hales, T. (Supervisor), 2014

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Development of mode of action tools using lysyl-tRNA synthetase to support Cryptosporidium drug discovery

  Hanna, J. C. (Author), Pawlowic, M. (Supervisor) & Wyllie, S. (Supervisor), 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Development of Next-Generation Protein Degradation Systems: BromoTag and Other PROTACs

  Bond, A. G. (Author), Ciulli, A. (Supervisor) & Sapkota, G. (Supervisor), 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Discovering de-S-acylating enzymes in Arabidopsis thaliana

  Laurila, M. (Author), Hemsley, P. (Supervisor) & Birch, P. (Supervisor), 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Discovery and characterization of a novel Deubiquitinase ZUP1

  Kwasna, D. B. (Author), Kulathu, Y. (Supervisor), 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Discovery of a novel meiotic E3 ubiquitin ligase by characterisation of the barley desynaptic mutant DES12.W

  Mittmann, S. U. (Author), Waugh, R. (Supervisor), Colas, I. (Supervisor) & Ramsay, L. (Supervisor), 2017

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Discovery of high quality molecular leads and screening collections for CNS drug targets

  Farnaby, W. (Author), Ciulli, A. (Supervisor) & Read, K. (Supervisor), 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Dissecting molecular mechanisms mediating ERK1/2 regulation of neural differentiation

  Raga Gil, E. (Author), Storey, K. (Supervisor) & Findlay, G. (Supervisor), 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Dissecting the molecular basis of the anti-bacterial activity of the Type VI Secretion System in Serratia marcescens 

  Mariano, G. (Author), Coulthurst, S. (Supervisor), 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Dissecting the puncturing device of the Type VI Secretion System: role of Hcp, VgrG and PAAR proteins in assembly and secretion of effectors

  Cianfanelli, F. R. (Author), Coulthurst, S. (Supervisor), 2016

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Dissecting the role of Ndc80 and Dam1 complexes in tethering kinetochores at the microtubule plus end: an in vivo approach

  Kalantzaki, M. (Author), Tanaka, T. (Supervisor), 2013

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Dock180/Elmo proteins are critical regulators of phagocytosis,macropinocytosis and chemotaxis in Dictyostelium

  Wang, J. (Author), Weijer, C. (Supervisor), 2006

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• DogTag – a novel genetically encoded proximity labeling strategy for problematic protein-protein interactions

  Myles, S. M. (Author), Hemsley, P. (Supervisor) & Birch, P. (Supervisor), 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Drug target deconvolution in Leishmania donovani

  De Sousa Paradela, L. (Author), Wyllie, S. (Supervisor) & Gilbert, I. (Supervisor), 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Early-stage drug discovery of HIV-1 frameshifting modulators

  Fernandes, A. B. (Author), Gray, D. (Supervisor) & Wilson, S. (Supervisor), 2015

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Elongin B/C-containing E3 ligases: fragment-based ligand design and examining resistance mechanisms for targeted protein degradation

  Casement, R. (Author), Ciulli, A. (Supervisor), 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Elucidating the biological function of the uncharacterised protein FAM83G/PAWS1: Role in Wnt signalling through its interaction with Caseine Kinase 1α

  Bozatzi, P. (Author), Sapkota, G. (Supervisor), 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Elucidating the permeation mechanisms of the TRPV and TRPM ion channels using in silico electrophysiology

  Ives, C. M. (Author), Zachariae, U. (Supervisor) & Barton, G. J. (Supervisor), 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Elucidating the role of bacterial SLC26 transporters

  Karinou, E. (Author), Javelle, A. (Supervisor), 2014

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Engineering Cell Lines to Investigate the Function of Mammalian SWI/SNF Complexes

  Blümli, S. (Author), Owen-Hughes, T. (Supervisor), 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Engineering durable late blight resistance to protect solanaceous plants

  Stevens, L. J. (Author), Birch, P. (Supervisor), Chapman, S. (Supervisor) & Hein, I. (Supervisor), 2016

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Engineering novel antibody-based molecules to probe the role of the immunoglobulin hinge and generate a potential cancer vaccine

  Leong, T. F. (Author), Woof, J. (Supervisor) & Meek, D. (Supervisor), 2017

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Environmental signals that control T lymphocytes in the gastrointestinal tract

  Ramsay, G. (Author), Cantrell, D. (Supervisor), 2015

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Establishing and Maintaining Cortical Asymmetry in Drosophila Neural Stem Cells

  Hannaford, M. (Author), Januschke, J. (Supervisor), 2017

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Establishing the role of RNF4 in the vertebrate DNA damage response

  Chua, S. J. (Author), Hay, R. (Supervisor) & Lane, D. (Supervisor), 2012

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Evaluation of Glycogen Synthase Kinase 3 as a drug target in African trypanosomes

  Grimaldi, R. (Author), Fairlamb, A. (Supervisor) & Frearson, J. A. (Supervisor), 2014

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Examining TRAF6 control of immunity and CD8+ T cells

  Bennett, K. (Author), Cantrell, D. (Supervisor) & Cohen, P. (Supervisor), 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Experimental and numerical analysis of behaviour of the myxospermous seeds of Capsella bursa-pastoris (L.) Medik. (shepherd’s purse) in soil

  Deng, W. (Author), Jeng, D.-S. (Supervisor) & Iannetta, P. (Supervisor), 2012

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Exploiting crosstalk between growth and immunity in plants : the role of the Phytophthora infestans effector AVR2 in potato late blight

  Turnbull, D. (Author), Birch, P. (Supervisor), Gilroy, E. (Supervisor) & Hein, I. (Supervisor), 2016

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Exploration of Alternative Proteases in Shotgun Proteomics to Increase Proteome and Splice Junction Coverage in Plants

  Puliasis, S. (Author), Zhang, R. (Supervisor), Hemsley, P. (Supervisor) & Lewandowska, D. (Supervisor), 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Exploring allosteric pockets in protein kinases: a multidisciplinary approach

  Birced, I. (Author), Hopkins, A. (Supervisor), 2015

  Student thesis: Master's Thesis › Master of Science

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• Exploring E3 ligase activity in CD8 T cells

  Bibi, H. (Author), Cantrell, D. (Supervisor), 2025

  Student thesis: Doctoral Thesis › Doctor of Science

• Exploring Human Population Variation in Repeat Proteins

  Tsenkov, M. I. (Author), Barton, G. (Supervisor) & van Aalten, D. (Supervisor), 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Exploring Parkinson’s disease associated LRRK2 and PINK1/Parkin signal transduction pathways within immune cells

  Joseph, T. (Author), Alessi, D. (Supervisor) & Muqit, M. (Supervisor), 2019

  Student thesis: Master's Thesis › Master of Science

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• Exploring the diversity of biofilms of the E. coli Species

  Yong, L. (Author), Stanley-Wall, N. (Supervisor) & Typas, N. (Supervisor), 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Exploring the molecular basis of host specific dynamic adaptation in Phytophthora capsici

  Cummins, M. (Author), Huitema, E. (Supervisor) & Birch, P. (Supervisor), 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Exploring the role of the RXLR-EER motifs in the secretion and translocation processes of Phytophthora infestans cytoplasmic effectors

  Xu, L. (Author), Birch, P. (Supervisor), Whisson, S. (Supervisor) & Boevink, P. (Supervisor), 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Folate transport and drug resistance in the African Trypanosome

  Dewar, S. (Author), Fairlamb, A. (Supervisor) & Horn, D. (Supervisor), 2017

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Fragment-based approaches to probe the surface of the VHL E3 ligase

  Castro, G. (Author), Ciulli, A. (Supervisor), 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Functional & Molecular Analysis of Bod1in Mitotic Chromosome Segregation

  Schleicher, K. (Author), Swedlow, J. (Supervisor), 2014

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Functional Characterisation of APETALA-2 Like Transcription Factors in Barley

  Shoesmith, J. (Author), McKim, S. (Supervisor) & Houston, K. (Supervisor), 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Function and inhibition of the mitochondrial O-GlcNAc transferase isoform

  Trapannone, R. (Author), Van Aalten, D. (Supervisor), 2015

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Function of two closely related fibroblast growth factors in early mesoderm development of Drosophila melanogaster

  Klingseisen, A. (Author), Muller, H.-A. (Supervisor), 2009

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Functions and Mechanisms of the ERK5 MAP Kinase in Pluripotent Stem Cells

  Brown, H. (Author), Findlay, G. (Supervisor) & Stavridis, M. (Supervisor), 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Functions and regulation of the RNF12 E3 ubiquitin ligase in intellectual disability

  Espejo Serrano, C. (Author), Findlay, G. (Supervisor) & Virdee, S. (Supervisor), 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Fungal Biomineralization of Metal Carbonate Nanoparticles

  Liu, F. (Author), Gadd , G. M. (Supervisor), 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Fungal transformation of phosphate minerals

  Bahri-Esfahani, J. (Author), Gadd, G. (Supervisor) & George, T. (Supervisor), 2014

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Fungi in the built environment: biodeterioration and bioprotection

  Zhao, J. (Author), Gadd, G. (Supervisor) & Dyer, T. (Supervisor), 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Generating barley plants with modified straw by suppressing HCT and C3H genes

  Magama, F. (Author), Halpin, C. (Supervisor), 2014

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Genetic Analysis of Ethiopian and Eritrean Barley Landraces

  Dinsa, G. (Author), Waugh, R. (Supervisor), Halpin, C. (Supervisor) & Russell, J. (Supervisor), 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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