School of Life Sciences

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• Targeting an E3 ubiquitin ligase Siah1 and a cysteine protease SENP1 using SPR and DSF-based fragment screening

  Rimsa, V. (Author), Hunter, W. (Supervisor), 2013

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Targeting final steps of sugar nucleotide biosynthetic pathway against Aspergillus fumigatus

  Yan, K. (Author), van Aalten, D. (Supervisor), 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Targeting the Rho1 GTPase signalling pathway in Aspergillus fumigatus

  Wei, W. (Author), Van Aalten, D. (Supervisor), 2017

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Tat signal peptide recognition during protein maturation and export

  Grahl, S. (Author), Sargent, F. (Supervisor), 2011

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The AMPK signalling pathway in cancer and DNA damage

  Dandapani, M. (Author), Hardie, D. (Supervisor), 2013

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Application of Pulsed Electron Paramagnetic Resonance to the Investigation of Protein Structure

  Stevens, M. (Author), Norman, D. (Supervisor), 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Behaviour of Bacillus subtilis Environmental Isolates in Complex Media

  Wood, A. (Author), Stanley-Wall, N. (Supervisor) & Coulthurst, S. (Supervisor), 2024

  Student thesis: Master's Thesis › Master of Science

• The biomechanical properties of epithelial cells and tissue in two and three dimensions

  Bentivegna, V. (Author), Nathke, I. (Supervisor) & Cochran, S. (Supervisor), 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The changing Phytophthora infestans population: implications for late blight epidemics and control

  Chapman, A. C. (Author), Birch, P. (Supervisor), Cooke, D. (Supervisor) & Lees, A. (Supervisor), 2012

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The chromatin landscape of barley: gene expression, evolution and epigenetics

  Baker, K. (Author), Flavell, A. (Supervisor) & Bayer, M. (Supervisor), 2015

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The costs and benefits of Bacillus subtilis extracellular protease production across different environmental contexts

  Rosazza, T. (Author), Stanley-Wall, N. (Supervisor) & Coulthurst, S. (Supervisor), 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Detection of Gastrointestinal Inflammation with Microultrasound and The Feasibility of Ultrasound Capsule Endoscopy

  Cox, B. F. (Author), Nathke, I. (Supervisor), Steele, B. (Supervisor) & Cochran, S. (Supervisor), 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The development and application of ubiquitin and SUMO-directed photoreactive probes

  Chandler, S. (Author), Hay, R. (Supervisor), 2025

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The Development of Cereblon Recruiting BromoTag Degraders for Targeted Protein Degradation

  Harris, A. (Author), Ciulli, A. (Supervisor) & Farnaby, W. (Supervisor), 2023

  Student thesis: Master's Thesis › Master of Science

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• The dual-targeted membrane assembly of the Streptomyces coelicolor Rieske protein

  Tooke, F. J. (Author), Palmer, T. (Supervisor), 2016

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Effect of Low Temperature on Alternative Splicing in Barley

  Raeside, A. (Author), Brown, J. (Supervisor) & Simpson, C. G. (Supervisor), 2016

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The effect of temperature stress on recombination in barley

  Arrieta Salgado, M. (Author), Ramsay, L. (Supervisor), Waugh, R. (Supervisor) & Colas, I. (Supervisor), 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Effects of Polysomal mRNA Association and Cap Methylation on Gene Expression in Trypanosoma brucei

  Kelner, A. (Author), Ferguson, M. (Supervisor) & Cowling, V. (Supervisor), 2014

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The evolution of signalling components regulating Dictyostelium somatic cell differentiation

  Forbes, G. (Author), Schaap, P. (Supervisor) & Weijer, C. (Supervisor), 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The functional and molecular characterisation of the novel DNA damage repair protein Bod1L

  Davies, A. M. (Author), Swedlow, J. (Supervisor), 2015

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The identification and characterisation of proteins interacting with SUMO-ubiquitin hybrid chains

  Anderson, O. (Author), Hay, R. (Supervisor), 2015

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Identification and Synthesis of Novel Fluorine Containing Heterocycles as Starting-Points of Fragment-Based Drug Discovery

  Preston, F. (Author), Wyatt, P. (Supervisor), Gilbert, I. (Supervisor) & Davidson, J. (Supervisor), 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The influence of temperature on the biofilm matrix composition of Bacillus species

  Stevenson, D. (Author), Stanley-Wall, N. (Supervisor) & MacPhee, C. E. (Supervisor), 2025

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The interplay of ion binding, receptor ionisation, and water molecules in the regulation of G-protein coupled receptor signalling: The development and application of a methodology to characterise protein-internal water and ion cavities and their mechanistic relationships from a mutual information perspective

  Thomson, N. (Author), Zachariae, U. (Supervisor) & Pisliakov, A. (Supervisor), 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Investigation of Oligosaccharyltransferase in Trypanosoma brucei

  Jinnelov, P. (Author), Ferguson, M. (Supervisor), 2014

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The metabolism of bicyclic nitro drugs in Leishmania

  Norval, S. (Author), Read, K. (Supervisor) & Fairlamb, A. (Supervisor), 2016

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The Metabolism of Drawing: a Rhizomic Thesis

  Dodds, H. (Author), Harrison, P. (Supervisor) & Prescott, A. (Supervisor), 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Non-Wnt Functions of APC: Unravelling the Link between APC and Apoptosis

  Cuddihy, J. (Author), Hiom, K. (Supervisor) & Nathke, I. (Supervisor), 2016

  Student thesis: Doctoral Thesis › Doctor of Medicine

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• The Persister Problem: Developing Assays to target persister cells in antibiotic screening studies

  Smith, M. C. (Author), Bergkessel, M. (Supervisor) & Read, K. (Supervisor), 2022

  Student thesis: Master's Thesis › Master of Science

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• The regulation and function of Forkhead box O transcription factors FOXO1 and FOXO3 in T and iNKT lymphocytes

  Nomura, A. (Author), Cantrell, D. (Supervisor), 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The regulation and function of mRNA cap methylation in pluripotency and differentiation

  Grasso, L. (Author), Cowling, V. (Supervisor), 2015

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The regulation of CD8+ T cells by nutrient availability

  Youdale, T. (Author), Cantrell, D. (Supervisor) & Ganley, I. (Supervisor), 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The regulation of mouse embryonic stem cell differentiation by Nrf2

  Wongpaiboonwattana, W. (Author), Stavridis, M. (Supervisor) & Dinkova-Kostova, A. (Supervisor), 2017

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The regulation of the Parkinson’s associated kinase PINK1

  Shaw, A. (Author), Muqit, M. (Supervisor), 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The role of Cdc7 and cyclin-dependent kinases in DNA replication and S phase

  Poh, W. T. (Author), Blow, J. (Supervisor) & Kaldis, P. (Supervisor), 2012

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Role of Cellular and Protein Context in Targeted Protein Degradation

  Glennie, L. (Author), Sapkota, G. (Supervisor) & Virdee, S. (Supervisor), 2025

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The role of extracellular signal-regulated kinases (ERKs) in T lymphocytes

  de Souza Damasio, M. P. (Author), Cantrell, D. (Supervisor), 2016

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Role of Hexokinase II and Glycolysis in Regulating Mitophagy

  Rosewell, P. J. (Author), Ganley, I. (Supervisor), 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The role of JAK1 and JAK3 in CD8⁺ effector T cells

  Rollings, C. (Author), Cantrell, D. (Supervisor), 2016

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Role of Notch Signalling in Amplifying the Cellular Response to Sonic Hedgehog during Dorsal-Ventral Patterning of the Spinal Cord

  Stasiulewicz, M. (Author), Dale, J. (Supervisor), 2015

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The role of pax genes in vertebrate segmentation

  Wright, D. (Author), Maroto, M. (Supervisor), 2010

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Role of Phytophthora Secreted Effectors in Determining Pathogen Host Range

  Thilliez, G. J. A. (Author), Huitema, E. (Supervisor), Hein, I. (Supervisor), Gilroy, E. (Supervisor) & Birch, P. (Supervisor), 2016

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The role of the chromatin remodeller ISWI in the cellular response to hypoxia

  Melvin, A. J. D. (Author), Rocha, S. (Supervisor), 2011

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Role of the Protein MTBP in DNA Replication

  Volpi, I. (Author), Blow, J. (Supervisor), 2017

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The structural analysis of histone H3 lysine 56 acetylation and related histone chaperone complexes

  Hammond, C. (Author), Owen-Hughes, T. (Supervisor), 2013

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The structure and function of TasA in the Bacillus subtilis biofilm matrix

  Erskine, E. (Author), Stanley-Wall, N. (Supervisor), 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Type VI Secretion Systems of Klebsiella pneumoniae and Enterobacter cloacae

  Mathers, K. I. (Author), Coulthurst, S. (Supervisor), 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Time Resolved Light Sheet Microscopy

  O'Brien, D. J. (Author), MacDonald, M. (Supervisor) & Lamond, A. (Supervisor), 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• To Design and Develop Semi-Saturated and Unsaturated Bicyclic Heterocycles for Fragment-Based Drug Discovery (FBDD) Campaigns

  Luise, N. (Author), Wyatt, P. (Supervisor), 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Towards an understanding of genetic control of processing quality traits in blackcurrant (Ribes nigrum L.)

  Jarret, D. A. (Author), Brennan, R. (Supervisor), Hancock, R. (Supervisor) & Flavell, A. (Supervisor), 2016

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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