School of Medicine

Projects

Projects per year 1999 2011 2012 2013 2014 2015 2017 2029

• 137 Not started
• 143 Active
• 1006 Finished

Projects per year

Search results

• Active

  Defining Stromal Biology In The Pathogenesis Of Oesophageal Cancer To Create A Novel Biomarker Signature To Aid Diagnosis, Prognosis And Treatment Strategies

  Kang, L., McLean, M. H. & Walsh, S.

  15/05/23 → 14/11/24

  Project: Research

• Application Of Machine Learning For Outbreak Investigation

  Eftimie, R., Marwick, C. & Parcell, B.

  1/05/23 → 31/10/24

  Project: Research

• Does mTOR Signalling Pathway Regulate Male And Female Gonad Sensitivity To Chemotherapy-Induced Damage Via Mitophagy Activation

  Lopes, F.

  1/05/23 → 30/04/25

  Project: Research

• Development of Therapeutic Strategies to Regenerate Pancreatic Beta Cells: Towards a Disease-Modifying Treatment for Type 1 Diabetes

  Cantley, J.

  Diabetes UK

  24/04/23 → 23/06/28

  Project: Research

  • Anniversaries and Special Events 100%
  • Pancreatic Extracts 64%
  • Glucagon-Secreting Cells 60%
  • Inventions 57%
  • Glucagon 40%

• Medicines In Acute and Chronic Care: HDRUK Driver Project (Joint with University of Birmingham and Liverpool)

  Pearson, E.

  Health Data Research UK

  1/04/23 → 31/03/28

  Project: Research

• The Effect Of Malaria Parasites On Dendritic Cell Metabolism (TEMPODM) (joint with University of Glasgow)

  Dinkova-Kostova, A.

  Biotechnology and Biological Sciences Research Council

  1/04/23 → 31/03/26

  Project: Research

• HIT 4HYPOS: Investigating Biomarkers And Signalling Pathways

  Farrell, C.

  1/04/23 → 31/01/24

  Project: Research

• Understanding the Impact of the National Change in Gabapentinoid Classification and the Risk Factors for Serious Harms

  Colvin, L., Hebert, H., Smith, B. & Wang, H.

  National Institute of Academic Anaesthesia

  1/04/23 → 30/06/24

  Project: Research

• HDR UK QQR2 Phenomics (joint with HDR UK and UCL and 30 others)

  Cole, C.

  Health Data Research UK

  1/04/23 → 31/03/28

  Project: Research

• The iDiabetes Initiative. Cardiac Biomarkers In Patients With Diabetes. A Genetic Substudy

  McCrimmon, R.

  1/04/23 → 31/03/25

  Project: Research

• What Is The Structural Basis Of HRI Activation By 1-Phenyl-3-(4-Phenoxy)Cyclohexyl)Ureas?

  Masson, G.

  31/03/23 → 30/03/24

  Project: Research

• Improving treatment efficacy in hypertension by biomarker-guided personalised decision support (HT-ADVANCE) (Joint with INSERM (lead), Radboud UMC, University Hospital Zurich, Dresden University Hospital and University of Glasgow and 8 other organisations)

  Cole, C. & Jefferson, E.

  1/03/23 → 28/02/29

  Project: Research

• Elucidating The Role Pf 5HT7 Receptors In B-Cell Lipotoxicity

  Patibandla, C.

  1/03/23 → 31/08/23

  Project: Research

• Design and Validation Of An Augmented Reality System for Simulated Thoracic Epidural Block Training on the Soft Embalmed Thiel Cadaver

  Erolin, C., Grunwald, I., Lamb, C. & McLeod, G.

  National Institute of Academic Anaesthesia

  1/03/23 → 31/08/24

  Project: Research

• Implementation and Validation of Quantitative Lysosome-specific GCase Assays in Cell Lines and Human Peripheral Blood for use in Clinical Samples

  Alessi, D. & Sammler, E.

  1/03/23 → 31/08/24

  Project: Research

• Neurodegeneration and Bone Health in SHHEC

  Belch, J. & Fitton, C.

  The Institute of Cardiovascular Research

  8/02/23 → 7/02/25

  Project: Research

• SATRE-Standardised Architecture for Trusted Research Environments (joint with UCL, UCL Hospital, Alan Turing Inst., Ulster University, STFC Hartree, Research Data Scotland)

  Cole, C. & Li, S.

  Medical Research Council

  1/02/23 → 31/10/23

  Project: Research

• Exploring The Training Needs Of GPs And GP Trainees In Relation To The Women's Health Plan's Priority Areas For Action

  Kennedy, C. & McElhinney, Z.

  Association for the Study of Medical Education

  1/02/23 → 31/01/24

  Project: Research

• Semi Automated Checking of Research Outputs (SACRO) - Joint with Universities Of West of England, Oxford & Edinburgh

  Cole, C.

  Medical Research Council

  1/02/23 → 31/10/23

  Project: Research

• DARE-FX: Delivering a Federated Network of TREs to Enable Safe Analytics - Joint with Universities of Manchester and Nottingham

  Cole, C.

  Medical Research Council

  1/02/23 → 31/10/23

  Project: Research

• UK Keratinocyte Cancer Collaborative: Cutaneous SCC Atlas And Biorepository (Joint with University of Cambridge, NHS Greater Glasgow and Clyde, Norfolk and Norwich University Hospital and Gloucestershire Hospitals NHS Foundation Trust) (BSF National Keratinocyte Cancer Research Award 2021)

  Proby, C.

  British Skin Foundation

  31/01/23 → 30/01/26

  Project: Research

• Establishing Predictors Of Response To Chemotherapy In Advanced Gastroesophageal Adenocarcinoma - PostHoc Analysis Of The GO2 Trial

  Baxter, M. & Petty, R.

  1/01/23 → 31/03/24

  Project: Research

• TRE For Smart Manufaturing Data Hub (Joint with University of Ulster, University of Edinburgh, University of Cambridge and STFC Hartree, DataLab)

  Cole, C.

  1/01/23 → 31/05/25

  Project: Research

• GREAT-2: A phase 2 trial of Gremubamab compared to placebo in participants with bronchiectasis and chronic Pseudomonas aeruginosa infection

  Chalmers, J.

  1/11/22 → 31/10/25

  Project: Research

• The Role of Nrf2 in the Tumour Microenvironment of IDH Wild-Type Glioma (Joint with University of Edinburgh)

  Dinkova-Kostova, A.

  Medical Research Council

  1/11/22 → 31/10/25

  Project: Research

  • Tumor Microenvironment 100%
  • Metabolic 78%
  • Neurodegenerative Diseases 55%
  • NF-E2 Transcription Factor 51%
  • Oxidative Stress 47%

• Precision Control Of Protein Dosage In Vivo (joint with University of Edinburgh)

  Wolf, R.

  Medical Research Council

  1/11/22 → 31/10/27

  Project: Research

• Use of Design Thinking To Improve The Quality Of Patient Triage In Primary Care (PhD Fellowship)

  Grant, S. & Lim, C.

  1/11/22 → 31/10/25

  Project: Research

• Adverse Childhood Experiences: Understanding the Impact on Multimorbidity in Adulthood, a Focus on Chronic Pain, Addiction and Mental Health (Wellcome Trust Clinical PhD Fellowship)

  Colvin, L. & Smith, B.

  Wellcome Trust

  1/11/22 → 31/10/25

  Project: Research

• Isotope Dilution Mass Spectrometry-Based Biomarkers For Management Of Aortic Aneurysm

  Choy, A. & Huang, J.

  17/10/22 → 16/10/24

  Project: Research

• Targeting Cilia Dysfunction As A Therapeutic Strategy For Bronchiectasis

  Shoemark, A.

  British Lung Foundation

  1/10/22 → 30/09/27

  Project: Research

• Combination Therapy with BIOlogics and Partial Enteral Nutrition in Adults with Active Ileocolonic Crohn's Disease (The BIOPIC Study) (Joint with University of Glasgow)

  Mowat, C.

  1/10/22 → 30/04/25

  Project: Research

• Characterization Of Cell Cycle Check Points And DNA Damage Response Pathways In Spermatogonial Stem Cells After Chemotherapy Exposure As A Way To Reduce Genotoxic Damage (lead: University of Dundee other instns: University of Edinburgh, University Of Utah)

  Lopes, F.

  1/09/22 → 29/02/24

  Project: Research

• A Single Kinase Modulates The Diverse Extracellular Phosphoproteome Of Glioblastoma Multiforme

  Banerjee, S.

  Medical Research Council

  1/08/22 → 31/07/26

  Project: Research

  • Glioblastoma 100%
  • SARS Virus 74%
  • Brain 49%
  • Single-Cell Analysis 34%
  • Inflammation 29%

• The Impact of Primary Care Led, FIT-Based, Triage of New Onset Colorectal Symptoms on Diagnostic Service Demand and the Diagnosis of Colorectal Cancer

  Mowat, C., Steele, B. & Wang, H.

  1/08/22 → 31/07/23

  Project: Research

• Inflammation And Salt-Inducible Kinases - A Potential Novel Therapeutic Strategy In Patients With Heart Failure

  Arthur, S., Khan, F. & Mordi, I.

  1/08/22 → 31/01/24

  Project: Research

  • Metformin 100%
  • Cardiovascular Diseases 67%
  • Clinical Studies 64%
  • Type 2 Diabetes Mellitus 23%
  • Sodium-Glucose Transporter 2 Inhibitors 22%

• The Extracellular Matrix (ECM) Remodelling And Receptor Activation Drives Adipose Tissue Malfunction In Obesity (Lead: UoD other instn: University of Edinburgh)

  Ashford, M. & Kang, L.

  Diabetes UK

  11/07/22 → 10/07/25

  Project: Research

  • Cell Surface Receptors 100%
  • Extracellular Matrix 97%
  • Obesity 80%
  • Integrins 43%
  • indolepropanol phosphate 38%

• LRRK2 Kinase Activity and Global Proteomic Markers in the Gut of PD and IBD Patients (Joint with Icahn School of Medicine Mount Sinai New York & Department Of Pathology & Immunology, Washington University School of Medicine)

  Alessi, D. & Sammler, E.

  1/07/22 → 31/12/23

  Project: Research

• The European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC 3)

  Chalmers, J.

  1/07/22 → 30/06/25

  Project: Research

• Is Blood-Brain Barrier Dysfunction In Alzheimer's Disease Driven By Altered Cellular Metabolism (Lead Dundee, joint with University Oxford, Cardiff University, University Edinburgh) - Fellowship

  Ashford, M., McLean, F. & McNeilly, A.

  Alzheimer's Research UK

  15/06/22 → 14/06/25

  Project: Research

• Does Nrf2 Provide Neuroprotection Against Diabetes-Associated Vascular Dysfunction (Fellowship)

  McNeilly, A.

  Academy of Medical Sciences

  1/06/22 → 31/05/24

  Project: Research

• SenseCheQ: Community-Based Sensory Testing for Early Identification of Chemotherapy Induced Peripheral Neuropathy (Mapping Complexity of Pain with the Advanced Pain Discovery Platform) (Joint with University of Bristol, University of Newcastle and University of Oxford)

  Colvin, L.

  Medical Research Council

  14/05/22 → 13/05/25

  Project: Research

• Does Apathy Predict Outcomes From Ultrasound Thalamotomy For Parkinson's And Essential Tremor? A Multimodel Clinical And Functional Imaging Study

  Gilbertson, T., Mackenzie, G. & Steele, D.

  1/05/22 → 30/04/25

  Project: Research

• The iDiabetes Platform - Enhanced Phenotyping of Patients With Diabetes For Precision Diagnosis, Prognosis and Treatment (Joint with NHS Education for Scotland and University of Aberdeen)

  Bell, S., Croudace, T., Cunningham, S., Dillon, J., Doney, A., Donnan, P., Farre, A., Lang, C., McCrimmon, R., Mordi, I., Palmer, C. & Pearson, E.

  1/05/22 → 30/04/26

  Project: Research

• Investigating The Role Of The Radical-SAM Enzyme Viperin In Beta Cells And The Development Of Type1 Diabetes (Lead: UoD, other instns: University of Oxford & University of Edinburgh)

  Cantley, J.

  Medical Research Council

  20/04/22 → 19/04/25

  Project: Research

• Protein Phosphorylation Dynamics: Investigating A New Dimension Of Regulatory Control

  Saurin, A.

  Wellcome Trust

  1/04/22 → 31/03/25

  Project: Research

  • M Phase Cell Cycle Checkpoints 100%
  • Phosphoric Monoester Hydrolases 74%
  • Microtubules 71%
  • Phosphotransferases 57%
  • Chromosome Segregation 30%

• Is Neutrophil Inflammatory Phenotype Regulated By Olfactomedin-4 In Bronchiectasis (Clinical Academic Fellowship)

  Chalmers, J. & Shoemark, A.

  1/04/22 → 31/03/25

  Project: Research

• Establishing the Oncogenic Phosphoproteome of Glioblastoma

  Banerjee, S.

  1/03/22 → 29/02/24

  Project: Research

  • Proteasome Inhibitor 100%
  • Pyrazoles 91%
  • Oncogenic 70%
  • Bioactivity 67%
  • Glioblastoma 60%

• A Randomised Controlled Trial Of A Facilitated Home-Based Rehabilitation Intervention In Patients With Heart Failure With Preserved Ejection Fraction And Their Caregivers: The REACH-HFpEF Study (Joint with NHST)

  Chalmers, J. & Mordi, I.

  GlaxoSmithKline, National Institute for Health Research

  1/03/22 → 31/12/25

  Project: Research

• Developing A Decision Support Tool To Enable Precision Treatment of Type 2 Diabetes (Lead: University of Exeter)

  Pearson, E.

  Medical Research Council

  1/03/22 → 28/02/25

  Project: Research

• Glial engulfment of human synapses in Amyotrophic Lateral Sclerosis (ALS)

  Henstridge, C. & Laszlo, Z.

  1/02/22 → 31/01/24

  Project: Research

  • Nerve Growth Factors 100%
  • Neuroglia 81%
  • hippocampus 70%
  • Glial Cell Line-Derived Neurotrophic Factor 63%
  • cultured cells 57%