School of Medicine

  • United Kingdom

Research Output 1972 2020

2020

Abnormal Reward Valuation and Event-Related Connectivity in Unmedicated Major Depressive Disorder

Rupprechter, S., Stankevicius, A., Huys, Q. J. M., Seriès, P. & Steele, D., 7 Jan 2020, In : Psychological Medicine.

Research output: Contribution to journalArticle

Major Depressive Disorder
Reward
Gyrus Cinguli
Depression
Decision Making

Addressing the Challenge of Polypharmacy

Mair, A., Wilson, M. & Dreischulte, T., Jan 2020, In : Annual Review of Pharmacology and Toxicology. 60

Research output: Contribution to journalArticle

Drug interactions
Drug therapy
Polypharmacy
Medicine
Aging of materials
3 Downloads (Pure)

A Mendelian randomization study provides evidence that adiposity and dyslipidemia lead to lower urinary albumin creatinine ratio, a marker of microvascular function

Casanova, F., Wood, A. R., Yaghootkar, H., Beaumont, R. N., Jones, S. E., Gooding, K. M., Aizawa, K., Strain, W. D., Hattersley, A. T., Khan, F., Shore, A. C., Frayling, T. M. & Tyrrell, J., 8 Jan 2020, In : Diabetes.

Research output: Contribution to journalArticle

Open Access
File
Adiposity
Dyslipidemias
Random Allocation
Albumins
Creatinine

An initial evaluation of the effect of a novel regional block needle with tip-tracking technology on the novice performance of cadaveric ultrasound-guided sciatic nerve block

McLeod, G. A., McKendrick, M., Taylor, A., Sadler, A., Halcrow, J., Mustafa, A., Seeley, J., Raju, P. & McKendrick, G., 1 Jan 2020, In : Anaesthesia. 75, 1, p. 80-88 10 p.

Research output: Contribution to journalArticle

Nerve Block
Sciatic Nerve
Needles
Technology
Cadaver

Anti-inflammatory reliever therapy for asthma

Lipworth, B., Chan, R. & RuiWen Kuo, C., Jan 2020, In : Annals of Allergy, Asthma & Immunology. 124, 1, p. 13-15 3 p.

Research output: Contribution to journalArticle

2 Downloads (Pure)
Open Access
File
Type 1 Diabetes Mellitus
Hypoglycemia
Epinephrine
Research Personnel
Neurobehavioral Manifestations

A rare case of non-clostridial infection in a non-diabetic patient

Darat, H. N., Kanodia, A. K., Yong, A. & Ram, B., 8 Jan 2020, In : BMJ Case Reports. 13, 1, e233467.

Research output: Contribution to journalArticle

Neck
Infection
Abscess
Suppuration
Fever

Balloon Eustachian tuboplasty for Eustachian tube dysfunction: report of long-term outcomes in a UK population

McMurran, A. E. L., Hogg, G. E., Gordon, S., Spielmann, P. M. & Jones, S. E., 8 Jan 2020, In : Journal of Laryngology and Otology. p. 1-7 7 p.

Research output: Contribution to journalArticle

Eustachian Tube
Population
Acoustic Impedance Tests
Conductive Hearing Loss
Otitis Media with Effusion
35 Downloads (Pure)

Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1

Casares Perez, L., García, V., Garrido-Rodríguez, M., Millán, E., Collado, J. A., García-Martín, A., Peñarando, J., Calzado, M. A., de la Vega, L. & Muñoz, E., Jan 2020, In : Redox Biology. 28, p. 1-15 15 p., 101321.

Research output: Contribution to journalArticle

Open Access
File
Cannabidiol
Keratinocytes
Antioxidants
Heme Oxygenase-1
Skin

Cognitive consequences of opioid use

Baldacchino, A., Steele, D., Davey, F. & Tolomeo, S., 2020, Cognition and Addiction: A Researcher's Guide from Mechanisms Towards Interventions. Verdejo-Garcia, A. (ed.). 1 ed. Academic Press, p. 179-198 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Cystic fibrosis lung disease and bronchiectasis

Chalmers, J. D., Jan 2020, In : The Lancet Respiratory Medicine. 8, 1, p. 12-14 3 p.

Research output: Contribution to journalComment/debate

5 Downloads (Pure)

Effects of once-weekly semaglutide vs once-daily canagliflozin on body composition in type 2 diabetes: a substudy of the SUSTAIN 8 randomised, controlled clinical trial

McCrimmon, R., Catarig, A-M., Frias, J. P., Lausvig, N. L., le Roux, C. W., Thielke, D. & Lingvay, I., 2 Jan 2020, In : Diabetologia. 13 p.

Research output: Contribution to journalArticle

Open Access
File
Body Composition
Type 2 Diabetes Mellitus
Randomized Controlled Trials
Fats
Therapeutics

Exploration of temporal bone anatomy using mixed reality (HoloLens): development of a mixed reality anatomy teaching resource prototype

Maniam, P., Schnell, P., Dan, L., Portelli, R., Erolin, C., Mountain, R. & Wilkinson, T., 2020, In : Journal of Visual Communication in Medicine. 43, 1, p. 17-26 10 p.

Research output: Contribution to journalArticle

Temporal Bone
Anatomy
Teaching
Technology
Anatomic Models

Functional herniated choroid plexus in brain parenchyma following VP shunt removal

El Sheikh, M., Fadelalla, M., Kanodia, A. K., Kouli, O., Peebles, M. & Hossain-Ibrahim, K., 8 Jan 2020, In : British Journal of Neurosurgery. p. 1-4 4 p.

Research output: Contribution to journalArticle

Ventriculoperitoneal Shunt
Choroid Plexus
Ependyma
Parietal Lobe
Astrocytoma

Genetic Risk and Atrial Fibrillation in Patients with Heart Failure

Kloosterman, M., Santema, B. T., Roselli, C., Nelson, C. P., Koekemoer, A., Romaine, S. P. R., Van Gelder, I. C., Lam, C. S. P., Artola, V. A., Lang, C., Ng, L. L., Metra, M., Anker, S. D., Filippatos, G. S., Dickstein, K., Ponikowski, P., van der Harst, P., Meer, P. V. D., Van Veldhuisen, D. J., Benjamin, E. J. & 3 others, Voors, A. A., Samani, N. J. & Rienstra, M., 9 Jan 2020, In : European Journal of Heart Failure. 21, 12

Research output: Contribution to journalArticle

Open Access
Atrial Fibrillation
Heart Failure
Single Nucleotide Polymorphism
Atrial Flutter
Genome-Wide Association Study
2 Downloads (Pure)

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Doney, A., Mordi, I., Palmer, C. N., Parry, H., Veluchamy, A. & Lang, C. C., 9 Jan 2020, In : Nature Communications. 11, 1, p. 1-12 12 p., 163.

Research output: Contribution to journalArticle

Open Access
File
Mendelian Randomization Analysis
pathogenesis
genome
Heart Failure
Genes

Impact of EMA regulatory label changes on systemic diclofenac initiation, discontinuation, and switching to other pain medicines in Scotland, England, Denmark, and The Netherlands

Morales, D. R., Morant, S. V., MacDonald, T. M., Mackenzie, I. S., Doney, A. S. F., Mitchell, L., Bennie, M., Robertson, C., Hallas, J., Pottegard, A., Ernst, M. T., Wei, L., Nicholson, L., Morris, C., M C, R., Overbeek, J. A., Smits, E. & W V, R., 3 Jan 2020, In : Pharmacoepidemiology and Drug Safety. 10 p.

Research output: Contribution to journalArticle

Diclofenac
Scotland
Denmark
England
Netherlands

Joint optimization based on direct sparse stereo visual-inertial odometry

Wen, S., Zhao, Y., Zhang, H., Lam, H. K. & Manfredi, L., 10 Jan 2020, In : Autonomous Robots. 19 p.

Research output: Contribution to journalArticle

Units of measurement
Cameras
Gravitation
Fusion reactions
Pixels

Neuromyelitis optica spectrum disorder and active tuberculosis

Grieve, J. K., Day, S., Connell, D. & O'Riordan, J., 2 Jan 2020, In : BMJ Case Reports. 13, 1, e231524.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Tuberculosis
Infection
Light
17 Downloads (Pure)

Preventing foot ulceration in diabetes: systematic review and meta-analyses of RCT data

Crawford, F., Nicolson, D. J., Amanna, A. E., Martin, A., Gupta, S., Leese, G. P., Heggie, R., Chappell, F. M. & McIntosh, H. H., Jan 2020, In : Diabetologia. 63, 1, p. 49-64 16 p.

Research output: Contribution to journalReview article

Open Access
File
Meta-Analysis
Foot
Foot Ulcer
Thermometry
Silicones

Prospective international multicenter pectopexy trial: Interim results and findings post surgery

Noé, G. K., Schiermeier, S., Papathemelis, T., Fuellers, U., Khudyakov, A., Altmann, H. H., Borowski, S., Morawski, P. P., Gantert, M., De Vree, B., Zbigniew, T., Ugarteburu, R. G. & Anapolski, M., Jan 2020, In : European Journal of Obstetrics and Gynecology and Reproductive Biology. 244, p. 81-86 6 p.

Research output: Contribution to journalArticle

Multicenter Studies
Defecation
Intestinal Obstruction
Infection
Hysterectomy

Reply

Gingles, C. R., Symon, R., Gandy, S. J., Struthers, A. D., Houston, G., MacDonald, T. M., Lang, C. C., Donnan, P. T. & George, J., 1 Jan 2020, In : Journal of Hypertension. 38, 1, p. 177-178 2 p.

Research output: Contribution to journalLetter

Teaching, reflecting, and learning: The value of an intercalated medical education programme

Muir, F., Bruce, J. & McConville, K., 14 Jan 2020, In : Medical Teacher. 6 p.

Research output: Contribution to journalArticle

Teaching
learning
Values
education
confidence
2 Downloads (Pure)

The Controversies and Difficulties of Diagnosing Primary Ciliary Dyskinesia

Shoemark, A., Rubbo, B., Haarman, E., Hirst, R. A., Hogg, C., Jackson, C. L., Nielsen, K. G., Papon, J. F., Robinson, P., Walker, W. T. & Lucas, J. S., 1 Jan 2020, In : American Journal of Respiratory and Critical Care Medicine. 201, 1, p. 120-122 3 p.

Research output: Contribution to journalLetter

Open Access
File
Ethics
Fertility
Assisted Reproductive Techniques
Therapeutics
Child Welfare

The Metastatic Early Prognostic (MEP) score

Downie, S., Lai, F. Y., Joss, J., Adamson, D. & Jariwala, A. C., 1 Jan 2020, In : The bone & joint journal. 102-B, 1, p. 72-81 10 p.

Research output: Contribution to journalArticle

Mortality
Hip Fractures
Neoplasm Metastasis
Thigh
Trauma Centers

The older surgical patient – to operate or not? A state of the art review

Santhirapala, R., Partridge, J. & MacEwen, C. J., 5 Jan 2020, In : Anaesthesia. 75, S1, p. e46-e53 9 p.

Research output: Contribution to journalReview article

Organized Financing
Long-Term Care
Decision Making

The year in cardiology: aorta and peripheral circulation

Heiss, C., Pitcher, A., Belch, J. J. F., De Carlo, M., Reinecke, H., Baumgartner, I., Mazzolai, L. & Aboyans, V., 6 Jan 2020, In : European Heart Journal.

Research output: Contribution to journalArticle

Translating clinical trials into improved real-world management of pain: Convergence of translational, population-based and primary care research

Gilron, I., Blyth, F. M. & Smith, B., Jan 2020, In : Pain. 161, 1, p. 36-42 7 p.

Research output: Contribution to journalArticle

Ultrasound Capsule Endoscopy With a Mechanically Scanning Micro-ultrasound: A Porcine Study

Qiu, Y., Huang, Y., Zhang, Z., Cox, B. F., Liu, R., Hong, J., Mu, P., Lay, H. S., Cummins, G., Desmulliez, M. P. Y., Clutton, E., Zheng, H., Qiu, W. & Cochran, S., 3 Jan 2020, In : Ultrasound in Medicine and Biology.

Research output: Contribution to journalArticle

Capsule Endoscopy
capsules
Swine
Equipment and Supplies
scanning
2019
87 Downloads (Pure)

3D-printing based Transducer Holder for Robotic Assisted Ultrasound Guided HIFU

Wang, J., Xiao, X., Huang, Z. & Melzer, A., Jul 2019, In : Procedia Manufacturing. 30, p. 3-10 8 p.

Research output: Contribution to journalArticle

Open Access
File
Robotic arms
Printing
Transducers
Robotics
Ultrasonics
2 Citations (Scopus)
29 Downloads (Pure)

4 DOFs hollow soft pneumatic actuator – HOSE

Manfredi, L., Putzu, F., Guler, S., Huan, Y. & Cuschieri, A., 28 Jan 2019, In : Materials Research Express. 6, 4, 045703.

Research output: Contribution to journalArticle

Open Access
File
Pneumatic actuators
Actuators
Degrees of freedom (mechanics)
Rubber
Torque

4th ESPT Conference: pharmacogenomics and personalized medicine - research progress and clinical implementation

Sipeky, C., Llerena, A., Manolopoulos, V. G., Pearson, E., Mlakar, V., Gozzo, L., Simmaco, M., Marchetti, P., Re, M. D., Stankovic, S., Meyer, U., Cascorbi, I., Ingelman-Sundberg, M., Suarez-Kurtz, G., Marc, J., Katsila, T., Paulmichl, M., Nofziger, C., Ansari, M., Drago, F. & 1 others, van Schaik, R. H., Oct 2019, In : Pharmacogenomics. 20, 15, p. 1063-1069 7 p.

Research output: Contribution to journalArticle

Precision Medicine
Pharmacogenetics
Research
Sicily
Italy
4 Downloads (Pure)

A 2 × 2 factorial, randomised, open-label trial to determine the clinical and cost-effectiveness of hypertonic saline (HTS 6%) and carbocisteine for airway clearance versus usual care over 52 weeks in adults with bronchiectasis: a protocol for the CLEAR clinical trial

Bradley, J. M., Anand, R., O'Neill, B., Ferguson, K., Clarke, M., Carroll, M., Chalmers, J., De Soyza, A., Duckers, J., Hill, A. T., Loebinger, M. R., Copeland, F., Gardner, E., Campbell, C., Agus, A., McGuire, A., Boyle, R., McKinney, F., Dickson, N., McAuley, D. F. & 1 others, Elborn, S., 19 Dec 2019, In : Trials. 20, 1, p. 1-10 10 p., 747.

Research output: Contribution to journalArticle

Open Access
File
Bronchiectasis
Cost-Benefit Analysis
Clinical Trials
Standard of Care
Sputum
14 Downloads (Pure)

A 30-Year Clinical and Magnetic Resonance Imaging Observational Study of Multiple Sclerosis and Clinically Isolated Syndromes

Chung, K. K., Altmann, D., Barkhof, F., Miszkiel, K., Brex, P. A., O'Riordan, J., Ebner, M., Prados, F., Cardoso, M. J., Vercauteren, T., Ourselin, S., Thompson, A., Ciccarelli, O. & Chard, D. T., 25 Nov 2019, In : Annals of Neurology. 11 p.

Research output: Contribution to journalArticle

Open Access
File
Multiple Sclerosis
Observational Studies
Magnetic Resonance Imaging
Chronic Progressive Multiple Sclerosis
Relapsing-Remitting Multiple Sclerosis
2 Citations (Scopus)
67 Downloads (Pure)

A balanced approach to identifying, prioritising and evaluating all potential consequences of quality improvement: modified Delphi study

Toma, M., Dreischulte, T., Gray, N. M. . & Guthrie, B., 23 Mar 2019, In : BMJ Open. 9, 3, p. 1-11 11 p., e023890.

Research output: Contribution to journalArticle

Open Access
File
Delphi Technique
Quality Improvement
Workload
Delivery of Health Care
26 Downloads (Pure)

Ability of verbal autopsy data to detect deaths due to uncontrolled hyperglycaemia: testing existing methods and development and validation of a novel weighted score

Blackstock, S., Witham, M. D., Wade, A. N., Crampin, A., Beran, D., Ogle, G. D. & Davies, J. I., 18 Oct 2019, In : BMJ Open. 9, 10, p. 1-8 8 p., e026331.

Research output: Contribution to journalArticle

Open Access
File
Hyperglycemia
Autopsy
Physicians
Malawi
South Africa
Ankle Fractures
Ankle Joint
Ligaments
Cadaver
Ankle

A case of aneurysmal subarchnoid haemorrhage and superficial siderosis complicated by prospagnosia, simultagnosia and alexia without agraphia

Fadelalla, M., Kanodia, A., Elsheikh, M., Ellis, J., Smith, V. & Hossain-Ibrahim, K., 2 Dec 2019, In : British Journal of Neurosurgery. p. 1-4 4 p.

Research output: Contribution to journalArticle

Pure Alexia
Prosopagnosia
Siderosis
Dyslexia
Subarachnoid Hemorrhage

A case of dissection in an ACUSEAL-modified HeRO graft

Bradley, N. A., Guthrie, G. & Suttie, S., 16 Dec 2019, In : Journal of Vascular Access. 4 p.

Research output: Contribution to journalArticle

Dissection
Transplants
Catheterization
False Aneurysm
Hematoma
7 Citations (Scopus)
27 Downloads (Pure)

A catalog of genetic loci associated with kidney function from analyses of a million individuals

LifeLines Cohort Study, Wuttke, M., Li, Y., Li, M., Sieber, K. B., Feitosa, M. F., Gorski, M., Tin, A., Wang, L., Chu, A. Y., Hoppmann, A., Kirsten, H., Giri, A., Chai, J-F., Sveinbjornsson, G., Tayo, B. O., Nutile, T., Fuchsberger, C., Marten, J., Cocca, M. & 33 others, Ghasemi, S., Xu, Y., Horn, K., Noce, D., van der Most, P. J., Sedaghat, S., Yu, Z., Akiyama, M., Afaq, S., Ahluwalia, T. S., Almgren, P., Amin, N., Ärnlöv, J., Bakker, S. J. L., Bansal, N., Baptista, D., Bergmann, S., Biggs, M. L., Biino, G., Boehnke, M., Boerwinkle, E., Boissel, M., Bottinger, E. P., Boutin, T. S., Brenner, H., Brumat, M., Burkhardt, R., Butterworth, A. S., Campana, E., Campbell, A., Smith, B. H., Köttgen, A. & Pattaro, C., Jun 2019, In : Nature Genetics. 51, 6, p. 957-972 16 p.

Research output: Contribution to journalArticle

Open Access
File
Genetic Loci
Kidney
Glomerular Filtration Rate
Chronic Renal Insufficiency
Translational Medical Research

Accidental bite injury

Mackie, L. & Laverick, S., 9 Aug 2019, In : British Dental Journal. 227, 3, p. 177 1 p.

Research output: Contribution to journalArticle

Accuracy and repeatability of a semi-quantitative barefoot pressure measurement method for clinical use: The Derks Calculation Method

Maetzler, M., Bochdansky, T. & Abboud, R. J., Jun 2019, In : Foot. 39, p. 136-139 4 p.

Research output: Contribution to journalArticle

Heel
Pressure
Confidence Intervals
Foot
Gait
8 Citations (Scopus)
56 Downloads (Pure)

Accuracy of High-Speed Video Analysis to Diagnose Primary Ciliary Dyskinesia

Rubbo, B., Shoemark, A., Jackson, C. L., Hirst, R., Thompson, J., Hayes, J., Frost, E., Copeland, F., Hogg, C., O'Callaghan, C., Reading, I. & Lucas, J. S., 1 May 2019, In : Chest. 155, 5, p. 1008-1017 10 p.

Research output: Contribution to journalArticle

Open Access
File
Kartagener Syndrome
Video Microscopy
Routine Diagnostic Tests
Guidelines
Referral and Consultation
52 Downloads (Pure)

Achieving Self-Directed Integrated Cancer Aftercare (ASICA) in melanoma: protocol for a randomised patient-focused pilot trial of delivering the ASICA intervention as a means to earlier detection of recurrent and second primary melanoma

Murchie, P., Masthoff, J., Walter, F. M., Rahman, K., Allan, J. L., Burrows, N., Proby, C., Lee, A. J., Johnston, M., Durrani, A., Depasquale, I., Brant, B., Neilson, A., Meredith, F., Treweek, S., Hall, S. & McDonald, A., 3 Jun 2019, In : Trials. 20, 1, p. 1-11 11 p., 318.

Research output: Contribution to journalArticle

Open Access
File
Aftercare
Melanoma
Self-Examination
Neoplasms
Skin
2 Citations (Scopus)
76 Downloads (Pure)

A cognitive forcing tool to mitigate cognitive bias: A randomised control trial

O'Sullivan, E. D. & Schofield, S. J., 8 Jan 2019, In : BMC Medical Education. 19, 1, p. 1-8 8 p., 12.

Research output: Contribution to journalArticle

Open Access
File
trend
diagnostic
Ireland
medical student
republic
Long-Term Potentiation
Estrogen Receptors
Synapses
Synaptic Transmission
AMPA Receptors