Systems Medicine

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

GABA-A Receptors Medicine & Life Sciences
gamma-Aminobutyric Acid Medicine & Life Sciences
Receptors, Serotonin, 5-HT3 Medicine & Life Sciences
Neurons Medicine & Life Sciences
Synapses Medicine & Life Sciences
General Anesthetics Medicine & Life Sciences
Cytochrome P-450 Enzyme System Medicine & Life Sciences
Brain Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Profiles

No photo of Abdulmalik Arab

Arab, Abdulmalik

Person: Research Postgraduate Student

Photo of Michael Ashford

Ashford, Michael

Person: Academic

19782023
No photo of Mirren Augustin

Augustin, Mirren

Person: Academic Related

Projects 2011 2025

Research Output 1977 2019

22 Downloads (Pure)

A high-fat diet induces rapid changes in the mouse hypothalamic proteome

McLean, F. H., Campbell, F. M., Langston, R. F., Sergi, D., Resch, C., Grant, C., Morris, A. C., Mayer, C. D. & Williams, L. M., 29 Apr 2019, In : Nutrition and Metabolism. 16, p. 1-16 16 p., 26.

Research output: Contribution to journalArticle

Open Access
File
High Fat Diet
Proteome
Palmitic Acid
Oleic Acid
Neuronal Plasticity

Amino acid substitutions in the human homomeric β3 GABAA receptor that enable activation by GABA

Gottschald Chiodi, C., Baptista-Hon, D., Hunter, W. & Hales, T., 15 Feb 2019, In : Journal of Biological Chemistry. 294, 7, p. 2375-2385 11 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Amino Acid Substitution
gamma-Aminobutyric Acid
Substitution reactions
Chemical activation
11 Downloads (Pure)

An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials

Henderson, C. J., Kapelyukh, Y., Scheer, N., Rode, A., McLaren, A., MacLeod, K., Lin, D., Wright, J., Stanley, L. A. & Wolf, C. R., Jun 2019, In : Drug Metabolism and Disposition. 47, 6, p. 601-615 15 p.

Research output: Contribution to journalArticle

Open Access
File
Drug Interactions
Clinical Trials
Pharmaceutical Preparations
Pharmacokinetics
Cytochrome P-450 CYP3A

Prizes

Aston Achievement Awards Excellent Research

Colin Murdoch (Recipient), 1 Jan 2017

Prize: Prize (including medals and awards)

Best poster prize (Naveed Akbar PhD student)

Faisel Khan (Recipient), 2012

Prize: Prize (including medals and awards)

Best poster prize (Naveed Akbar PhD student)

Faisel Khan (Recipient), 2012

Prize: Prize (including medals and awards)

Activities 1995 2019

Leuchars Primary School (3)

Colin Henderson (Member), Frances Fuller-Pace (Member), Amy Rogers (Member), Li Kang (Member), Jennifer Kennedy (Member)
26 Apr 2019

Activity: Other activity typesSchools engagement

St Joseph's Primary School

Colin Henderson (Member), Ros Langston (Member), Tania G. Frangova (Member), Chandani Hennayake (Member), Annie Hasib (Member)
10 May 2019

Activity: Other activity typesSchools engagement

Student theses

Characterisation of leptin mimetic agents as therapeutic targets in Alzheimer's disease

Author: Malekizadeh, Y., 2016

Supervisor: Harvey, J. (Supervisor) & Irving, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Comorbid opioid dependence and chronic pain: Clinical implications

Author: Higgins, C., 2018

Supervisor: Matthews, K. (Supervisor) & Smith, B. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Nonlinear Dynamics of Microcirculation and Energy Metabolism for the Prediction of Cardiovascular Risk

Author: Smirni, S., 2018

Supervisor: Khan, F. (Supervisor) & MacDonald, M. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy