Keyphrases
Defluorination
100%
Guanine
100%
Active Sites
60%
Fluoroacetate
56%
Structural Insights
54%
HIV Capsid
50%
Capsid Binding
50%
NMR Crystallography
50%
Non-structural Protein 14
50%
Haloacid Dehalogenase
50%
Fluoroacetate Dehalogenase
50%
Transforming Genes
50%
Difluoroacetate
50%
Hydrolases
50%
Neuroepithelial Cells
50%
Methyltransferase
50%
Anticancer Drugs
50%
N7-methyltransferase
50%
Hydrolytic
50%
RhoA
50%
High-throughput Screening Assays
50%
RapidFire Mass Spectrometry
50%
COVID-19
50%
Miniprotein
50%
Binding Fragment
50%
Fragment Screening
50%
Screening Platform
50%
Coronavirus
40%
Molecular Dynamics Calculations
33%
Dehalogenase
26%
X-ray Crystallography
20%
Catalytic Mechanism
20%
Substrate Promiscuity
20%
Fluorine Atom
16%
Chloroacetate
16%
Fluorinated Compounds
16%
Carbon-halogen Bond
16%
Iodinated
16%
Structural Constraints
16%
Brominated
16%
Highly Similar
16%
Structure Dynamics
16%
Constraint-based
16%
Overall Structure
16%
Homologous Enzymes
16%
Effective Interaction
16%
X-ray Structure
16%
N-terminal Domain
16%
Weak Binding
16%
Drug Resistance
16%
Biochemistry, Genetics and Molecular Biology
Defluorination
100%
Active Site
68%
Hydrolase
58%
Anticancer
50%
RNA
50%
Capsid
50%
Oncogene
50%
Neuroepithelial Cell
50%
Human Immunodeficiency Virus
50%
Methyltransferase
50%
Enzyme
50%
Guanine
50%
Crystal Structure
35%
Enzymatic Hydrolysis
33%
Dynamics
20%
X-Ray Crystallography
18%
Catalytic Mechanism
16%
Life Cycle
12%
C-Terminus
12%
Drug Resistance
12%
N-Terminus
12%
Guanine Nucleotide Exchange Factor
11%
X Ray
10%
Conformation
10%
Messenger RNA
10%
Nostoc
8%
Rhodopseudomonas palustris
8%
Dechloromonas
8%
Protein-Ligand Docking
8%
Site-Directed Mutagenesis
8%
Bioremediation
8%
Biocatalyst
8%
Liquid Chromatography-Mass Spectrometry
8%
Catalytic Triad
8%
Protomer
8%
Copurification
5%
GTPase
5%
Protein-Protein Interaction
5%
IC50
5%
Guanosine Triphosphate
5%
S-Adenosyl Methionine
5%
Methylation
5%
Eukaryote
5%
Maturation
5%
Mutagenesis
5%
7-Methylguanosine
5%
Medicine and Dentistry
Guanine
100%
Methyltransferase
100%
Human Immunodeficiency Virus
50%
Virus Capsid
50%
Coronavirus
50%
High Throughput Screening
50%
Mass Spectrum
50%
Severe Acute Respiratory Syndrome Coronavirus 2
50%
NMR Spectroscopy
50%
Methylation
18%
HIV/AIDS
16%
Amino Terminal Sequence
16%
Carboxy Terminal Sequence
16%
X-Ray Crystallography
16%
Drug Resistance
16%
Viral Life Cycle
16%
Exonuclease
12%
Nitazoxanide
12%
Mutational Analysis
12%
Host Resistance
12%
Virus Genome
12%
Virus Replication
12%
Infection
12%
Guanosine
12%
Coronavirinae
12%
COVID-19
12%
Virus RNA
12%
Public Health
12%
SARS Coronavirus
12%
Helix
11%
Messenger RNA
11%
RNA Methyltransferase
5%
Maturation
5%
7 Methylguanosine
5%
S-Adenosyl Methionine
5%
Mutagenesis
5%
