Projects per year
Personal profile
Biography
Educated at Hymers Collge Hull, before stuying medicine and biochemistry at the University of Edinburgh.
ACADEMIC AND PROFESSIONAL HISTORY
1971-72 Surgical and Medical House Officer, Longmore and Western General Hospitals, Edinburgh
1972-75 Faculty of Medicine Research Scholar, University of Edinburgh (supervisor Dr I B R Bowman)
1975-76 MRC Travelling Fellow, University of Amsterdam (Prof Piet Borst)
1976-80 Research Fellow, University of Edinburgh (Dr I B R Bowman)
1980-81 Research Fellow, London School of Hygiene and Tropical Medicine (Prof W Peters)
1981-87 Assistant Professor, The Rockefeller University, New York (Prof A Cerami)
1987-90 Senior Clinical Lecturer, London School of Hygiene & Tropical Medicine
1990-96 Professor of Molecular Parasitology and Head, Biochemistry & Chemotherapy Unit, LSHTM
1996- Wellcome Principal Research Fellow, Professor of Biochemistry and Head of Division of Biological Chemistry & Drug Discovery (1996-2102), University of Dundee
2006- Co-Director Drug Discovery Unit, University of Dundee
Biography
HONOURS AND AWARDS
1987 Seymour H. Hutner Prize, Society of Protozoologists
1988 Frederick Murgatroyd Prize, Royal College of Physicians
1989 Fellow of the Linnean Society, London
1991 Ernst A.H. Friedheim Commemorative Lecture, Rockefeller University, New York
1993 Co-vice chairman (with Immo Scheffler) Gordon Research Conference on Polyamines
1995 Co-chairman (with Immo Scheffler) Gordon Research Conference on Polyamines
1996 John Scaife Commemorative Lecture, Edinburgh
1996 C.A.Wright Medal, British Society for Parasitology
1999 Foreign Corresponding Member, National Academy of Medicine of Buenos Aires, Argentina
2001 Fellow of the Royal Society of Edinburgh
2005 Fellow of the Academy of Medical Sciences
2005 Kitasato Microbial Chemistry Medal, Kitasato Institute, Japan
2005 Commander of the British Empire for services to medical science
2006 3Rs Prize 2006 for Refinement and Reduction of Animal Models of Leishmaniasis
2011 Fellow of the Society of Biology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, A study of glycerophosphate oxidase in Trypanosoma brucei., University of Edinburgh
Award Date: 1 Jan 1975
Bachelor of Medicine and Bachelor of Surgery, University of Edinburgh
Award Date: 1 Jan 1971
Bachelor of Science, University of Edinburgh
Award Date: 1 Jan 1968
External positions
Governing Board member & trustee
2010 → …
Keywords
- RM Therapeutics. Pharmacology
- Parasitology
- drug discovery
- drug resistance
- mode of drug action
- malaria
- African trypanosomiasis
- leishmaniasis
- Chagas disease
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Dive into the research topics where Alan Fairlamb is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Wellcome Centre for Anti-Infectives Research
Cook, S. (Investigator), De Rycker, M. (Investigator), Fairlamb, A. (Investigator), Ferguson, M. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Horn, D. (Investigator), Pawlowic, M. C. (Investigator), Read, K. (Investigator), Wyatt, P. (Investigator) & Wyllie, S. (Investigator)
1/04/17 → 31/03/25
Project: Research
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Target Assessment for Drug Discovery Against the Kinetoplastida
Dhir, R. (Investigator), Fairlamb, A. (Investigator) & Ferguson, M. (Investigator)
Project: Research
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Aref#d: 12419. The establishment of a Post-Genomics and Molecular Interactions Centre at the University of Dundee (Joint Infrastructure Fund - supplement)
Cohen, P. (Investigator), Downes, P. (Investigator), Fairlamb, A. (Investigator), Ferguson, M. (Investigator), Hunter, B. (Investigator), Lamond, A. (Investigator), Lilley, D. (Investigator), Norman, D. (Investigator), Watts, C. (Investigator) & Williams, J. (Investigator)
Project: Research
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Extension to College of Life Sciences Research Complex to Create a Centre for Translational and Interdisciplinary Research (Wolfson Award)
Barton, G. (Investigator), Chaplain, M. (Investigator), Fairlamb, A. (Investigator), Ferguson, M. (Investigator), Gilbert, I. (Investigator), Hopkins, A. (Investigator), Lamond, A. (Investigator), Swedlow, J. (Investigator) & Wyatt, P. (Investigator)
Project: Research
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The Relationship Between Visceral Leishmaniasis and Arsenic Contamination in Groundwater in Bihar, India (Clinical PhD Programme: Meghan Perry)
Cantrell, D. (Investigator), Fairlamb, A. (Investigator), Lambert, J. (Investigator) & Marshall, S. (Investigator)
Project: Research
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Sterol 14-alpha demethylase (CYP51) activity in Leishmania donovani is likely dependent upon cytochrome P450 reductase 1
Tulloch, L., Tinti, M., Wall, R., Weidt, S. K., Corpas Lopez, V., Dey, G., Smith, T. K., Fairlamb, A., Barrett, M. P. & Wyllie, S. (Lead / Corresponding author), 11 Jul 2024, In: PLoS Pathogens. 20, 7, 23 p., e1012382.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Downloads (Pure) -
Validation of Trypanosoma cruzi inactivation techniques for laboratory use
MacLean, L. M. (Lead / Corresponding author), Ariyanayagam, M., Sastry, L., Paterson, C., De Rycker, M. & Fairlamb, A. H. (Lead / Corresponding author), 18 Apr 2024, In: PLoS ONE. 19, 4, 12 p., e0300021.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Downloads (Pure) -
Author Correction: Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis (Nature, (2018), 560, 7717, (192-197), 10.1038/s41586-018-0356-z)
Wyllie, S., Thomas, M., Patterson, S., Crouch, S., De Rycker, M., Lowe, R., Gresham, S., Urbaniak, M. D., Otto, T. D., Stojanovski, L., Simeons, F. R. C., Manthri, S., MacLean, L. M., Zuccotto, F., Homeyer, N., Pflaumer, H., Boesche, M., Sastry, L., Connolly, P. & Albrecht, S. & 12 others, , 4 Jul 2023, In: Nature. 619, p. E48 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
The critical role of mode of action studies in kinetoplastid drug discovery
Fairlamb, A. H. (Lead / Corresponding author) & Wyllie, S. (Lead / Corresponding author), 10 May 2023, In: Frontiers in Drug Discovery. 3, 13 p., 1185679.Research output: Contribution to journal › Article › peer-review
Open AccessFile67 Downloads (Pure) -
Monocyclic Nitro-heteroaryl Nitrones with Dual Mechanism of Activation: Synthesis and Antileishmanial Activity
Pacheco, J. D. S., Costa, D. D. S., Cunha-Júnior, E. F., Andrade-Neto, V. V., Fairlamb, A. H., Wyllie, S., Goulart, M. O. F., Santos, D. C., Silva, T. L., Alves, M. A., Costa, P. R. R. (Lead / Corresponding author), Dias, A. G. (Lead / Corresponding author) & Torres-Santos, E. C. (Lead / Corresponding author), 9 Sept 2021, In: ACS Medicinal Chemistry Letters. 12, 9, p. 1405-1412 8 p.Research output: Contribution to journal › Letter › peer-review
Open AccessFile8 Citations (Scopus)58 Downloads (Pure)
Datasets
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Whole Genome Sequencing Variant Call Files for Trypanosoma brucei clones resistant to nifurtimox or fexinidazole
Fairlamb, A. (Creator), Foth, B. (Creator) & Berriman, M. (Creator), University of Dundee, 2015
DOI: 10.15132/10000107
Dataset
File
Prizes
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3Rs Prize 2006 for Refinement and Reduction of Animal Models of Leishmaniasis
Fairlamb, A. (Recipient) & Wyllie, S. (Recipient), 2006
Prize: Prize (including medals and awards)
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C.A.Wright Medal, British Society for Parasitology
Fairlamb, A. (Recipient), 1996
Prize: Prize (including medals and awards)
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Commander of the British Empire
Fairlamb, A. (Recipient), 2005
Prize: Prize (including medals and awards)
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Fellow of the Academy of Medical Sciences
Fairlamb, A. (Recipient), 2005
Prize: Election to learned society
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Fellow of the Linnean Society, London
Fairlamb, A. (Recipient), 1989
Prize: Election to learned society
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Bonding
Floyd, A. (Host), Fong, E. (Chair), Mackintosh, A. (Host), Fairlamb, A. (Chair), Aitken, J. (Member of programme committee), Farrell, S. (Participant), Thomas, M. (Participant), Tarver, G. (Participant), Postis, V. (Participant), McGinnis, C. (Participant), Read, K. (Participant), Seizova, S. (Participant), Cleghorn, L. (Participant), Baragana, B. (Participant), Pearson, L.-A. (Participant), Bellany, F. (Participant), Pinto, E. (Participant), Simeons, F. (Participant), Godoy Magalhaes, L. (Participant), Bayliss, T. (Participant), Akwensi, J. (Participant), De Sousa Paradela, L. (Participant), Wyllie, S. (Participant), Anderson, G. (Participant), Wu, S. (Participant) & Urbanowska, A. (Participant)
16 Feb 2023 → 8 Apr 2023Activity: Participating in or organising an event types › Festival/Exhibition
File -
Parasite Soup - Word Broth
Floyd, A. (Host), Fong, E. (Host), Fairlamb, A. (Presenter), Wyllie, S. (Presenter), Mackintosh, A. (Host), Mackenna, G. (Speaker), Simeons, F. (Participant), Nagar, R. (Participant) & Urch, J. (Participant)
6 Apr 2023Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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The WeeCAIR Medicinal Garden
Goddard, C. (Member), Floyd, A. (Member), De Sousa Paradela, L. (Member), Naylor, C. (Member), Shepherd, S. (Member), McGinnis, C. (Member), Hallyburton, I. (Member), Farrell, S. (Member), Frediani, K. (Member), Fairlamb, A. (Member), Crawford, A. (Member), Busak, H. (Member), Brown, C. (Member), Peet, C. (Member), Knatko, E. (Member), Onyame, H. (Member), Pacheco, J. (Member), Godoy Magalhaes, L. (Member), Jarron, M. (Member), Dixit, P. (Member), Niven, S. (Member) & Mackintosh, A. (Member)
2020 → 2022Activity: Other activity types › Other
Press/Media
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Tuberculosis drug may also target visceral leishmaniasis
24/05/16
1 item of Media coverage
Press/Media: Research
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Potential new treatment identified for Leishmaniasis
1/02/12 → 2/02/12
2 items of Media coverage
Press/Media: Research
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Drug breakthrough in fight against neglected diseases
Wyatt, P., Fairlamb, A. H. & Ferguson, M. A. J.
1/04/10
1 item of Media coverage
Press/Media: Research