Fairlamb, Alan


1993 …2022
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Personal profile


Educated at Hymers Collge Hull, before stuying medicine and biochemistry at the University of Edinburgh.


1971-72       Surgical and Medical House Officer, Longmore and Western General Hospitals, Edinburgh

1972-75       Faculty of Medicine Research Scholar, University of Edinburgh (supervisor Dr I B R Bowman)

1975-76       MRC Travelling Fellow, University of Amsterdam (Prof Piet Borst)

1976-80       Research Fellow, University of Edinburgh (Dr I B R Bowman)

1980-81       Research Fellow, London School of Hygiene and Tropical Medicine (Prof W Peters)

1981-87       Assistant Professor, The Rockefeller University, New York (Prof A Cerami)

1987-90       Senior Clinical Lecturer, London School of Hygiene & Tropical Medicine

1990-96        Professor of Molecular Parasitology and Head, Biochemistry & Chemotherapy Unit, LSHTM

1996-           Wellcome Principal Research Fellow, Professor of Biochemistry and Head of Division of Biological Chemistry & Drug Discovery (1996-2102), University of Dundee

2006-           Co-Director Drug Discovery Unit, University of Dundee



1987       Seymour H. Hutner Prize, Society of Protozoologists

1988       Frederick Murgatroyd Prize, Royal College of Physicians

1989       Fellow of the Linnean Society, London

1991       Ernst A.H. Friedheim Commemorative Lecture, Rockefeller University, New York

1993       Co-vice chairman (with Immo Scheffler) Gordon Research Conference on Polyamines

1995       Co-chairman (with Immo Scheffler) Gordon Research Conference on Polyamines

1996       John Scaife Commemorative Lecture, Edinburgh

1996       C.A.Wright Medal, British Society for Parasitology

1999       Foreign Corresponding Member, National Academy of Medicine of Buenos Aires, Argentina

2001       Fellow of the Royal Society of Edinburgh

2005       Fellow of the Academy of Medical Sciences

2005       Kitasato Microbial Chemistry Medal, Kitasato Institute, Japan

2005       Commander of the British Empire for services to medical science

2006       3Rs Prize 2006 for Refinement and Reduction of Animal Models of Leishmaniasis

2011       Fellow of the Society of Biology


Education/Academic qualification

Doctor of Philosophy, University of Edinburgh

Bachelor of Medicine and Bachelor of Surgery, University of Edinburgh

Bachelor of Science, University of Edinburgh

External positions

Governing Board member & trustee

2010 → …


  • RM Therapeutics. Pharmacology
  • Parasitology
  • drug discovery
  • drug resistance
  • mode of drug action
  • malaria
  • African trypanosomiasis
  • leishmaniasis
  • Chagas disease

Fingerprint Dive into the research topics where Alan Fairlamb is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 14 Similar Profiles
Trypanosoma brucei brucei Medicine & Life Sciences
Parasites Medicine & Life Sciences
Trypanosomiasis Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Leishmania donovani Medicine & Life Sciences
African Trypanosomiasis Medicine & Life Sciences
Visceral Leishmaniasis Medicine & Life Sciences
Nitroreductases Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2022

Research Output 1993 2019

4 Citations (Scopus)
108 Downloads (Pure)

Current and Future Prospects of Nitro-compounds as Drugs for Trypanosomiasis and Leishmaniasis

Fairlamb, A. H. & Patterson, S., 2019, In : Current Medicinal Chemistry. 26, 23, p. 4454-4475 22 p.

Research output: Contribution to journalReview article

Open Access
Nitro Compounds

Fexinidazole for the treatment of human African trypanosomiasis

Fairlamb, A., Dec 2019, In : Drugs of Today . 55, 11, p. 705-712 8 p., 705.

Research output: Contribution to journalArticle

African Trypanosomiasis
Trypanosoma brucei gambiense
Spinal Puncture
Granulocyte-Macrophage Colony-Stimulating Factor
6 Citations (Scopus)
145 Downloads (Pure)

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Baragaña, B., Forte, B., Choi, R., Nakazawa Hewitt, S., Bueren-Calabuig, J. A., Pisco, J. P., Peet, C., Dranow, D. M., Robinson, D. A., Jansen, C., Norcross, N. R., Vinayak, S., Anderson, M., Brooks, C. F., Cooper, C. A., Damerow, S., Delves, M., Dowers, K., Duffy, J., Edwards, T. E. & 57 others, Hallyburton, I., Horst, B. G., Hulverson, M. A., Ferguson, L., Jiménez-Díaz, M. B., Jumani, R. S., Lorimer, D. D., Love, M. S., Maher, S., Matthews, H., McNamara, C. W., Miller, P., O'Neill, S., Ojo, K. K., Osuna-Cabello, M., Pinto, E., Post, J., Riley, J., Rottmann, M., Sanz, L. M., Scullion, P., Sharma, A., Shepherd, S. M., Shishikura, Y., Simeons, F. R. C., Stebbins, E. E., Stojanovski, L., Straschil, U., Tamaki, F. K., Tamjar, J., Torrie, L. S., Vantaux, A., Witkowski, B., Wittlin, S., Yogavel, M., Zuccotto, F., Angulo-Barturen, I., Sinden, R., Baum, J., Gamo, F-J., Mäser, P., Kyle, D. E., Winzeler, E. A., Myler, P. J., Wyatt, P. G., Floyd, D., Matthews, D., Sharma, A., Striepen, B., Huston, C. D., Gray, D. W., Fairlamb, A. H., Pisliakov, A. V., Walpole, C., Read, K. D., Van Voorhis, W. C. & Gilbert, I. H., 2 Apr 2019, In : Proceedings of the National Academy of Sciences. 116, 14, p. 7015-7020 6 p.

Research output: Contribution to journalArticle

Open Access
Lysine-tRNA Ligase
Cryptosporidium parvum
Plasmodium falciparum
4 Citations (Scopus)
133 Downloads (Pure)

Nongenotoxic 3-Nitroimidazo[1,2-a]pyridines Are NTR1 Substrates That Display Potent in Vitro Antileishmanial Activity

Fersing, C., Basmaciyan, L., Boudot, C., Pedron, J., Hutter, S., Cohen, A., Castera-Ducros, C., Primas, N., Laget, M., Casanova, M., Bourgeade-Delmas, S., Piednoel, M., Sournia-Saquet, A., Belle Mbou, V., Courtioux, B., Boutet-Robinet, É., Since, M., Milne, R., Wyllie, S., Fairlamb, A. H. & 5 others, Valentin, A., Rathelot, P., Verhaeghe, P., Vanelle, P. & Azas, N., 10 Jan 2019, In : ACS Medicinal Chemistry Letters. 10, 1, p. 34-39 6 p.

Research output: Contribution to journalArticle

Open Access
Inhibitory Concentration 50
Display devices
2 Citations (Scopus)
118 Downloads (Pure)
Open Access
Leishmania donovani
Pharmaceutical Preparations


Whole Genome Sequencing Variant Call Files for Trypanosoma brucei clones resistant to nifurtimox or fexinidazole

Fairlamb, A. (Creator), Foth, B. (Creator), Berriman, M. (Creator), University of Dundee, 2015



Press / Media

Tuberculosis drug may also target visceral leishmaniasis

Alan H. Fairlamb & Kevin Read


1 item of Media coverage

Press/Media: Research

Potential new treatment identified for Leishmaniasis

Alan H. Fairlamb


2 items of Media coverage

Press/Media: Research


Arsenic, antimony and visceral leishmaniasis

Author: Perry, M. R., 2014

Supervisor: Fairlamb, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy


Assessment of N-myristoyltransferase and the N-myristoylomeas a potential chemotherapeutic target inTrypanosoma cruzi

Author: Roberts, A., 2014

Supervisor: Fairlamb, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy


Evaluation of Glycogen Synthase Kinase 3 as a drug target in African trypanosomes

Author: Grimaldi, R., 2014

Supervisor: Fairlamb, A. (Supervisor) & Frearson, J. A. (External person) (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy


Folate transport and drug resistance in the African Trypanosome

Author: Dewar, S., 2017

Supervisor: Fairlamb, A. (Supervisor) & Horn, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy


Nitroaromatic pro-drug activation and resistance in the African trypanosome

Author: Sokolova, A. Y., 2011

Supervisor: Fairlamb, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy