Keyphrases
Trypanothione Reductase
100%
Trypanosoma Brucei
77%
Trypanothione
76%
Trypanosoma Cruzi (T. cruzi)
60%
Leishmania Donovani
39%
Crithidia Fasciculata
38%
Trypanosomatids
35%
Glutathionylspermidine
34%
Antitrypanosomal Activity
32%
Spermidine
32%
Glutathione
31%
Leishmania
30%
T. Brucei
28%
Trypanosome
26%
Drug Target
25%
Visceral Leishmaniasis
23%
Glutathione Reductase
23%
Human African Trypanosomiasis
22%
Disulfide
22%
African Trypanosomes
21%
Drug Discovery
21%
Recombinant
19%
Metabolism
19%
Plasmodium Falciparum
19%
Trypanothione Synthetase
18%
Leishmania Major
18%
Synthetase
16%
Polyamines
16%
Tryparedoxin
14%
Active Sites
13%
Nicotinamide Adenine Dinucleotide Phosphate (NADPH)
13%
Nitroreductase
13%
Tryparedoxin Peroxidase
13%
Fexinidazole
13%
Chemotherapy
12%
Trypanosomiasis
12%
Chagas Disease
12%
Nitro
11%
Leishmaniasis
11%
Oxides
10%
Pteridine Reductase 1
10%
Glyoxalase
10%
Phenothiazine
10%
Trypanothione Reductase Inhibitors
10%
Malaria
9%
New Drugs
9%
Hydrogen Peroxide
9%
Kinetoplastid
9%
Antimonials
9%
EC50
9%
Pharmacology, Toxicology and Pharmaceutical Science
Trypanothione Reductase
85%
Trypanothione
72%
Trypanosoma Brucei
47%
Trypanosoma
40%
Trypanosoma Cruzi
39%
Glutathione
30%
Trypanosomatidae
28%
African Trypanosomiasis
28%
Antitrypanosomal
27%
Leishmania donovani
22%
Synthetase
22%
Leishmania
21%
Visceral Leishmaniasis
20%
Disulfide
20%
Glutathione Reductase
19%
Drug Discovery
19%
Polyamine
18%
Spermidine
17%
Crithidia fasciculata
17%
Peroxidase
17%
Diseases
17%
Nitroreductase
14%
Arsenical
13%
Fexinidazole
13%
EC50
12%
Chagas Disease
12%
Lactoperoxidase
12%
Leishmania Major
12%
Antimonial
11%
Thiol
11%
Leishmaniasis
11%
Oxidoreductase
10%
Drug Development
10%
Structure Activity Relationship
10%
Pharmacokinetics
10%
Phenothiazine
10%
Chemotherapy
10%
Trypanosoma Brucei Brucei
9%
Drug Resistance
9%
Plasmodium falciparum
9%
Mouse Model
9%
Reduced Nicotinamide Adenine Dinucleotide Phosphate
9%
Protozoon
8%
Cytotoxicity
8%
Kinetoplastida
8%
Nifurtimox
8%
Hydrogen Peroxide
8%
Pentamidine
7%
Antimalarial Agent
7%
Epimastigote
7%
Biochemistry, Genetics and Molecular Biology
Trypanothione
65%
Enzyme
50%
Oxidoreductase
44%
Reductase
42%
Trypanosoma Brucei
35%
Crithidia fasciculata
33%
Trypanosomatidae
24%
Glutathione
22%
Trypanosoma
22%
Leishmania Major
18%
Trypanosoma Cruzi
17%
Anabolism
16%
Disulfide
15%
Metabolic Pathway
13%
Leishmania
13%
Peroxidase
11%
Glutathione Reductase
10%
Escherichia coli
9%
Active Site
9%
Crystal Structure
9%
Lactoperoxidase
8%
Leishmania donovani
8%
Protozoon
8%
Amidase
7%
Enzyme Specificity
7%
Plasmodium falciparum
7%
Thiol
6%
Wild Type
6%
Lactoylglutathione Lyase
6%
Metabolite
6%
Genetics
6%
Cysteine
6%
Binding Site
6%
Methylglyoxal
6%
Kinetoplastida
5%
Amino Acids
5%
Dihydrofolate Reductase
5%
Oxidative Stress
5%
Folic Acid
5%
Synthase
5%
Tripeptide
5%
Turnover Number
5%
Copurification
5%