• 11575 Citations
  • 61 h-Index
1988 …2019
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Research Output 1988 2019

1999
52 Citations (Scopus)

Nuclear organisation of NIPP1, a regulatory subunit of protein phosphatase 1 that associates with pre-mRNA splicing factors

Trinkle-Mulcahy, L., Ajuh, P., Prescott, A., Claverie-Martin, F., Cohen, S., Lamond, A. I. & Cohen, P., 19 Feb 1999, In : Journal of Cell Science. 112, 2, p. 157-168 12 p.

Research output: Contribution to journalArticle

Open Access
Protein Phosphatase 1
RNA Precursors
Phosphoprotein Phosphatases
Carrier Proteins
Binding Sites
31 Citations (Scopus)

The eye lens cytoskeleton

Quinlan, R. A., Sandilands, A., Procter, J. E., Prescott, A. R., Hutcheson, A. M., Dahm, R., Gribbon, C., Wallace, P. & Carter, J. M., May 1999, In : Eye (Basingstoke). 13, 3, p. 409-416 8 p.

Research output: Contribution to journalArticle

Crystalline Lens
Cytoskeleton
Lenses
Intermediate Filaments
Cell Shape
1998
343 Citations (Scopus)

AMP-activated protein kinase: Greater AMP dependence, and preferential nuclear localization, of complexes containing the α2 isoform

Salt, I., Celler, J. W., Hawley, S. A., Prescott, A., Woods, A., Carling, D. & Hardie, D. G., 15 Aug 1998, In : Biochemical Journal. 334, 1, p. 177-187 11 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Adenosine Monophosphate
Protein Isoforms
Phosphotransferases
Adenosine Triphosphate
61 Citations (Scopus)

Changes in the nucleolar and coiled body compartments precede lamina and chromatin reorganization during fibre cell denucleation in the bovine lens

Dahm, R., Gribbon, C., Quinlan, R. A. & Prescott, A. R., Mar 1998, In : European Journal of Cell Biology. 75, 3, p. 237-246 10 p.

Research output: Contribution to journalArticle

Coiled Bodies
Lenses
Chromatin
Apoptosis
Mitochondrial Degradation
6 Citations (Scopus)

Susceptibility of lens epithelial and fibre cells at different stages of differentiation to apoptosis

Dahm, R., Gribbon, C., Quinlan, R. A. & Prescott, A. R., Nov 1998, In : Biochemical Society Transactions. 26, 4, p. 118 1 p., S349.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Three murine cataract mutants (Cat2) are defective in different γ- crystallin genes

Klopp, N., Favor, J., Löster, J., Lutz, R. B., Neuhäuser-Klaus, A., Prescott, A., Pretsch, W., Quinlan, R. A., Sandilands, A., Vrensen, G. F. J. M. & Graw, J., 1 Sep 1998, In : Genomics. 52, 2, p. 152-158 7 p.

Research output: Contribution to journalArticle

Crystallins
Cataract
Mutation
Genes
Exons
1997
35 Citations (Scopus)

Antigen endocytosis and presentation mediated by human membrane IgG1 in the absence of the IgA/Igβ dimer

Knight, A. M., Lucocq, J. M., Prescott, A. R., Ponnambalam, S. & Watts, C., 1 Jul 1997, In : EMBO Journal. 16, 13, p. 3842-3850 9 p.

Research output: Contribution to journalArticle

Antigen Presentation
Endocytosis
Dimers
Immunoglobulin A
Immunoglobulin G
276 Citations (Scopus)
Histocompatibility
Major Histocompatibility Complex
Dendritic Cells
Bone Marrow
Antigens
106 Citations (Scopus)

Distinct compartmentalization of TGN46 and β1,4-galactosyltransferase in HeLa cells

Prescott, A. R., Lucocq, J. M., James, J., Lister, J. M. & Ponnambalam, S., Mar 1997, In : European Journal of Cell Biology. 72, 3, p. 238-246 9 p.

Research output: Contribution to journalArticle

Galactosyltransferases
HeLa Cells
Confocal Microscopy
Immunoelectron Microscopy
Golgi Apparatus
8 Citations (Scopus)

Lens cell organeile loss during differentiation versus stress-induced apoptotic changes

Dahm, R., Gribbon, C., Quinlan, R. A. & Prescott, A. R., Nov 1997, In : Biochemical Society Transactions. 25, 4, 1 p., S584.

Research output: Contribution to journalArticle

108 Citations (Scopus)

Structural characterisation of two forms of procyclic acidic repetitive protein expressed by procyclic forms of Trypanosoma brucei

Treumann, A., Zitzmann, N., Hulsmeier, A., Prescott, A. R., Almond, A., Sheehan, J. & Ferguson, M. A. J., 20 Jun 1997, In : Journal of Molecular Biology. 269, 4, p. 529-547 19 p.

Research output: Contribution to journalArticle

154 Citations (Scopus)

The prohibitin family of mitochondrial proteins regulate replicative lifespan

Coates, P. J., Jamieson, D. J., Smart, K., Prescott, A. R. & Hall, P. A., 1997, In : Current Biology. 7, 8, p. 607-610 4 p.

Research output: Contribution to journalArticle

Mitochondrial Proteins
Yeast
Genes
Yeasts
yeasts
1996
1 Citation (Scopus)

Chicken CP49: Significant or paltry

Wallace, P. S., Duff, S. V., Prescott, A. R., Goebel, D., Maisel, H. & Quinlan, R. A., 1 Jan 1996, In : Ophthalmic Research. 28, 1, p. 55-57 3 p.

Research output: Contribution to journalArticle

Invertebrates
Lenses
Chickens
Lamins
Intermediate Filament Proteins
33 Citations (Scopus)

Mutations which block the binding of calmodulin to Spc110p cause multiple mitotic defects

Stirling, D. A., Rayner, T. F., Prescott, A. R. & Stark, M. J. R., 1996, In : Journal of Cell Science. 109, p. 1297-1310 14 p.

Research output: Contribution to journalArticle

Nuclear proenkephalin induces cell death in a P53 dose-dependent manner

Devvar, D. A., Spraggon, C., Midgeley, C., Lane, D., Prescott, A. & Spruce, B. A., 1 Nov 1996, In : Biochemical Society Transactions. 24, 4, p. 571S 1 p., E51.

Research output: Contribution to journalArticle

Cell death
Cell Death
Fibroblasts
Cells
Secretory Pathway
Crystalline Lens
Cell death
Cell Nucleus
Lenses
Cell Differentiation
49 Citations (Scopus)

The beaded filament of the eye lens: An unexpected key to intermediate filament structure and function

Quinlan, R. A., Carter, J. M., Sandilands, A. & Prescott, A. R., 1 Jan 1996, In : Trends in Cell Biology. 6, 4, p. 123-126 4 p.

Research output: Contribution to journalComment/debate

Crystalline Lens
Crystallins
Intermediate Filaments
Lenses
Polymers
28 Citations (Scopus)

The intermediate filament cytoskeleton of the lens: An ever changing network through development and differentiation

Prescott, A. R., Sandilands, A., Hutcheson, A. M., Carter, J. M. & Quinlan, R. A., 1 Jan 1996, In : Ophthalmic Research. 28, 1, p. 58-61 4 p.

Research output: Contribution to journalArticle

Intermediate Filaments
Cytoskeleton
Lenses
Cell Differentiation
Polymers
1995
323 Citations (Scopus)

Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages

Norbury, C. C., Hewlett, L. J., Prescott, A. R., Shastri, N. & Watts, C., Dec 1995, In : Immunity. 3, 6, p. 783-791 9 p.

Research output: Contribution to journalArticle

Bone Marrow
Macrophages
Antigens
T-Lymphocytes
Brefeldin A
55 Citations (Scopus)

Filensin is proteolytically processed during lens fiber cell differentiation by multiple independent pathways

Sandilands, A., Prescott, A. R., Hutcheson, A. M., Quinlan, R. A., Casselman, J. T. & FitzGerald, P. G., 1 Jan 1995, In : European Journal of Cell Biology. 67, 3, p. 238-253 16 p.

Research output: Contribution to journalArticle

Lenses
Cell Differentiation
Vimentin
filensin
Peptides
237 Citations (Scopus)

Gadd45 is a nuclear cell cycle regulated protein which interacts with p21Cip1

Kearsey, J. M., Coates, P. J., Prescott, A. R., Warbrick, E. & Hall, P. A., 2 Nov 1995, In : Oncogene. 11, 9, p. 1675-1683 9 p.

Research output: Contribution to journalArticle

Cell Cycle Proteins
Nuclear Proteins
Cell Cycle
Two-Hybrid System Techniques
Cyclin-Dependent Kinases
10 Citations (Scopus)

Synaptogenesis and distribution of presynaptic axonal varicosities in low density primary cultures of neocortex: an immunocytochemical study utilizing synaptic vesicle-specific antibodies, and an electrophysiological examination utilizing whole cell recording

Lowenstein, P. R., Shering, A. F., Morrison, E., Tomasec, P., Bain, D., Jacob, T. J. C., Wu, J., Prescott, A. & Castro, M. G., 1 Apr 1995, In : Journal of Neurocytology. 24, 4, p. 301-317 17 p.

Research output: Contribution to journalArticle

Synaptic Vesicles
Neocortex
Patch-Clamp Techniques
Dendrites
Presynaptic Terminals
108 Citations (Scopus)

Vimentin and CP49/filensin form distinct networks in the lens which are independently modulated during lens fibre cell differentiation

Sandilands, A., Prescott, A. R., Carter, J. M., Hutcheson, A. M., Quinlan, R. A., Richards, J. & Fitzgerald, P. G., 1 Apr 1995, In : Journal of Cell Science. 108, 4, p. 1397-1406 10 p.

Research output: Contribution to journalArticle

Vimentin
Lenses
Cell Differentiation
Intermediate Filament Proteins
Confocal Microscopy
1994
19 Citations (Scopus)

A Correlated Study of Metabolic Cell Communication and Gap Junction Distribution in the Adult Frog Lens

Prescott, A., Duncan, G., Van Marle, J. & Vrensen, G., Jun 1994, In : Experimental Eye Research. 58, 6, p. 737-746 10 p.

Research output: Contribution to journalArticle

Intercellular Junctions
Gap Junctions
Cell Communication
Anura
Lenses
71 Citations (Scopus)

Recognition of the major cell surface glycoconjugates of Leishmania parasites by the human serum mannan-binding protein

Green, P. J., Feizi, T., Stoll, M. S., Thiel, S., Prescott, A. & McConville, M. J., Aug 1994, In : Molecular and Biochemical Parasitology. 66, 2, p. 319-328 10 p.

Research output: Contribution to journalArticle

Mannose-Binding Lectin
Glycoconjugates
Leishmania
Mannose
Parasites
289 Citations (Scopus)

The coated pit and macropinocytic pathways serve distinct endosome populations

Hewlett, L. J., Prescott, A. R. & Watts, C., 1 Mar 1994, In : Journal of Cell Biology. 124, 5, p. 689-703 15 p.

Research output: Contribution to journalArticle

Endosomes
Population
Brefeldin A
Endocytosis
Clathrin-Coated Vesicles
1993

Corrigenda: PPX, a novel protein serine/threonine phosphatase localized to centrosomes (The EMBO Journal (1993) 12 (9870996))

Brewis, N. D., Street, A. J., Prescott, A. R. & Cohen, P. T. W., May 1993, In : EMBO Journal. 12, 5, 1 p.

Research output: Contribution to journalComment/debate

31 Citations (Scopus)

Cytoskeletal changes associated with cell motility.

Warn, R., Brown, D., Dowrick, P., Prescott, A. & Warn, A., 1993, In : Symposia of the Society for Experimental Biology. 47, p. 325-338 14 p.

Research output: Contribution to journalReview article

Microtubules
Cell Movement
Pinocytosis
Phenotype
Cell Polarity
187 Citations (Scopus)

PPX, a novel protein serine/threonine phosphatase localized to centrosomes

Brewis, N. D., Street, A. J., Prescott, A. R. & Cohen, P. T. W., 1 Mar 1993, In : EMBO Journal. 12, 3, p. 987-996 10 p.

Research output: Contribution to journalArticle

Centrosome
Phosphoprotein Phosphatases
Antibodies
Staining and Labeling
Telophase
1992
22 Citations (Scopus)

Stable and slow-turning-over microtubules characterize the processes of motile epithelial cells treated with scatter factor

Prescott, A. R., Dowrick, P. G. & Warn, R. M., 1 May 1992, In : Journal of Cell Science. 102, 1, p. 103-112 10 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Microtubules
Epithelial Cells
Tubulin
Biotin
1991
10 Citations (Scopus)

Diamide induces reversible changes in morphology, cytoskeleton and cell-cell coupling in lens epithelial cells

Prescott, A. R., Stewart, S., Duncan, G., Gowing, R. & Warn, R. M., Jan 1991, In : Experimental Eye Research. 52, 1, p. 83-92 10 p.

Research output: Contribution to journalArticle

Diamide
Cytoskeleton
Lenses
Epithelial Cells
Epithelium
10 Citations (Scopus)

Microtubules rich in post-translationally modified α-tubulin form distinct arrays in frog lens epithelial cells

Prescott, A. R., Webb, S. F., Rawlins, D., Shaw, P. J. & Warn, R. M., Jun 1991, In : Experimental Eye Research. 52, 6, p. 743-753 11 p.

Research output: Contribution to journalArticle

Tubulin
Microtubules
Anura
Lenses
Epithelial Cells
26 Citations (Scopus)

Scatter factor affects major changes in the cytoskeletal organization of epithelial cells

Dowrick, P. G., Prescott, A. R. & Warn, R. M., Jul 1991, In : Cytokine. 3, 4, p. 299-310 12 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Talin
Vinculin
Epithelial Cells
Stress Fibers
1989
7 Citations (Scopus)

Incorporation of tubulin from an evolutionarily diverse source, Physarum polycephalum, into the microtubules of a mammalian cell.

Prescott, A. R., Foster, K. E., Warn, R. M. & Gull, K., 1 Apr 1989, In : Journal of Cell Science. 92 , 4, p. 595-605 11 p.

Research output: Contribution to journalArticle

Physarum polycephalum
Tubulin
Microtubules
Physarum
Spindle Apparatus
13 Citations (Scopus)

Microtubules rich in modified α-tubulin characterize the tail processes of motile fibroblasts

Prescott, A. R., Vestberg, M. & Warn, R. M., 1 Oct 1989, In : Journal of Cell Science. 94, 2, p. 227-236 10 p.

Research output: Contribution to journalArticle

1988
18 Citations (Scopus)

Effects of elevated intracellular magnesium on cytoskeletal integrity

Prescott, A. R., Comerford, J. G., Magrath, R., Lamb, N. J. C. & Warn, R. M., 1 Mar 1988, In : Journal of Cell Science. 89, 3, p. 321-329 9 p.

Research output: Contribution to journalArticle

Microtubules
Magnesium
Actins
Stress Fibers
Rhodamines
19 Citations (Scopus)

Membrane and communication properties of tissue cultured human lens epithelial cells

Stewart, S., Duncan, G., Marcantonio, J. M. & Prescott, A. R., Nov 1988, In : Investigative Ophthalmology and Visual Science. 29, 11, p. 1713-1725 13 p.

Research output: Contribution to journalArticle

Lenses
Epithelial Cells
Communication
Membranes
Coloring Agents
22 Citations (Scopus)

Membrane and junctional properties of the isolated frog lens epithelium

Duncan, G., Stewart, S., Prescott, A. R. & Warn, R. M., Jun 1988, In : The Journal of Membrane Biology. 102, 3, p. 195-204 10 p.

Research output: Contribution to journalArticle

Anura
Lenses
Coloring Agents
Epithelium
Octanols
5 Citations (Scopus)

Scanning electron microscopy and the transformed phenotype

Linstead, P., Jennings, B., Prescott, A., Hawley, P., Warn, R. & Gibson, I., 1988, In : Micron And Microscopica Acta. 19, 3, p. 155-162 8 p.

Research output: Contribution to journalArticle

ras Genes
Electron Scanning Microscopy
Proto-Oncogene Proteins p21(ras)
Phenotype
Oncogene Proteins