Freeman, Alasdair

Dr

  • United Kingdom

  • 190 Citations
  • 8 h-Index
20032019
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Fingerprint Dive into the research topics where Alasdair Freeman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 23 Similar Profiles
Enzymes Medicine & Life Sciences
Deoxyribonuclease I Medicine & Life Sciences
Cruciform DNA Medicine & Life Sciences
DNA Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Ions Medicine & Life Sciences
Fungi Medicine & Life Sciences
Crystal structure Chemical Compounds

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Research Output 2003 2019

  • 190 Citations
  • 8 h-Index
  • 12 Article
  • 1 Chapter (peer-reviewed)
15 Downloads (Pure)

Junction resolving enzymes use multivalency to keep the Holliday junction dynamic

Zhou, R., Yang, O., Declais, A-C., Jin, H., Gwon, G. H., Freeman, A., Cho, Y., Lilley, D. & Ha, T., 1 Mar 2019, In : Nature Chemical Biology. 15, 3, p. 269-275 7 p.

Research output: Contribution to journalArticle

Open Access
File
Cruciform DNA
Enzymes
Genetic Recombination
Bacteriophage T7
Chromosome Segregation
1 Citation (Scopus)
39 Downloads (Pure)
Open Access
File
Ions
DNA
Enzymes
Substrate Specificity
Catalytic Domain
1 Citation (Scopus)

Biochemical and Structural Properties of Fungal Holliday Junction-Resolving Enzymes

Liu, Y., Freeman, A., Déclais, A-C., Gartner, A. & Lilley, D. M. J., 2018, Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination. Spies, M. & Malkova, A. (eds.). Academic Press, Vol. 600. p. 543-568 26 p. (Methods in Enzymology; vol. 600).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Cruciform DNA
Structural properties
Enzymes
Chaetomium
DNA
63 Downloads (Pure)
Open Access
File
Deoxyribonuclease I
Peptides
DNA
Enzymes
Proteins
18 Citations (Scopus)
54 Downloads (Pure)

Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA

Liu, Y., Freeman, A. D. J., Déclais, A. C., Wilson, T. J., Gartner, A. & Lilley, D. M. J., 22 Dec 2015, In : Cell Reports. 13, 11, p. 2565-2575 11 p.

Research output: Contribution to journalArticle

Open Access
File
Crystal structure
DNA
Enzymes
2-Aminopurine
Crystal lattices