Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 5 Similar Profiles
NF-E2-Related Factor 2 Medicine & Life Sciences
NAD Medicine & Life Sciences
Oxidoreductases Medicine & Life Sciences
Transcription Factors Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Oxidative Stress Medicine & Life Sciences
Oxidation-Reduction Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Research Output 2001 2018

Author Correction: Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates

Bartolome, F., Esteras, N., Martin-Requero, A., Boutoleau-Bretonniere, C., Vercelletto, M., Gabelle, A., Ber, I. L., Honda, T., Dinkova-Kostova, A. T., Hardy, J., Carro, E. & Abramov, A. Y. 1 Mar 2018 In : Scientific Reports. 8, p. 1-2 2 p., 4064

Research output: Contribution to journalArticle

Open Access
File
Energy Metabolism
Mutation

C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape

Dayalan Naidu, S., Muramatsu, A., Saito, R., Asami, S., Honda, T., Hosoya, T., Itoh, K., Yamamoto, M., Suzuki, T. & Dinkova-Kostova, A. 23 May 2018 In : Scientific Reports. 8, p. 1-12 12 p., 8037

Research output: Contribution to journalArticle

Open Access
File
Cysteine
Lipopolysaccharides
Interleukin-6
Up-Regulation
Macrophages
2 Citations
Open Access
File
NF-E2-Related Factor 2
Fructose
Liver Cirrhosis
Fats
Endoplasmic Reticulum Stress

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Mills, E. L. , Ryan, D. G. , Prag, H. A. , Dikovskaya, D. , Menon, D. , Zaslona, Z. , Jedrychowski, M. P. , Costa, A. S. H. , Higgins, M. , Hams, E. , Szpyt, J. , Runtsch, M. C. , King, M. S. , McGouran, J. F. , Fischer, R. , Kessler, B. M. , McGettrick, A. F. , Hughes, M. M. , Carroll, R. G. , Booty, L. M. & 15 others Knatko, E. V., Meakin, P. J., Ashford, M. L. J., Modis, L. K., Brunori, G., Sévin, D. C., Fallon, P. G., Caldwell, S. T., Kunji, E. R. S., Chouchani, E. T., Frezza, C., Dinkova-Kostova, A. T., Hartley, R. C., Murphy, M. P. & O'Neill, L. A. 5 Apr 2018 In : Nature. 556, 7699, p. 113-117 5 p.

Research output: Contribution to journalLetter

Alkylation
Anti-Inflammatory Agents
Interferon Type I
Cysteine
Lipopolysaccharides

Phenethyl isothiocyanate, a dual activator of transcription factors NRF2 and HSF1

Dayalan Naidu, S., Suzuki, T., Yamamoto, M., Fahey, J. W. & Dinkova-Kostova, A. 30 Apr 2018 In : Molecular Nutrition & Food Research.

Research output: Contribution to journalSpecial issue

Open Access
isothiocyanates
heat stress
transcription factors
Vegetables
Glucosinolates

Thesis

Investigating the role of transcription factors Nrf2 and Pparα in hepatic lipid metabolism during fasting

Author: Tebay, L., 2015

Supervisor: Hayes, J. (Supervisor) & Dinkova-Kostova, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Regulation of transcription factors NRF2 and HSF1 in mediating cellular stress responses

Author: Dayalan Naidu, S., 2016

Supervisor: Dinkova-Kostova, A. (Supervisor) & Hayes, J. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Single cell analysis of Keap1-Nrf2 dynamics

Author: Baird, L., 2013

Supervisor: Dinkova-Kostova, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

The regulation of mouse embryonic stem cell differentiation by Nrf2

Author: Wongpaiboonwattana, W., 2017

Supervisor: Stavridis, M. (Supervisor) & Dinkova-Kostova, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy