Projects per year
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- 4 Similar Profiles
Ubiquitin-Protein Ligases
Medicine & Life Sciences
pantothenate synthetase
Medicine & Life Sciences
Proteolysis
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Ligands
Medicine & Life Sciences
Molecules
Chemical Compounds
Cullin Proteins
Medicine & Life Sciences
Mycobacterium tuberculosis
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2013 2022
Bump-BET; Bump and Hole Approach to Ellucidate Function of Individual Bromodomains of BET Proteins (Marie Curie Fellowship)
1/10/15 → 30/09/17
Project: Research
Understanding the Molecular Details as the Basis of Epigenetic Readers Function (Fellowship)
Bortoluzzi, A. & Ciulli, A.
1/10/15 → 30/09/16
Project: Research
High Throughput Biolayer Interferometry at Dundee for Anti-Microbial and Interaction Studies
Birch, P., Ciulli, A., Fairlamb, A., Gray, D., Hunter, B., Owen-Hughes, T., Palmer, T., Ryan, R., Sargent, F., Stanley-Wall, N. & van Aalten, D.
Biotechnology and Biological Sciences Research Council
22/01/15 → 21/01/16
Project: Research
Research Output 2008 2019
Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs
Girardini, M., Maniaci, C., Hughes, S., Testa, A. & Ciulli, A., 22 Feb 2019, In : Bioorganic & Medicinal Chemistry. 14 p.Research output: Contribution to journal › Article
Open Access
Proteolysis
Ubiquitin-Protein Ligases
Degradation
Cullin Proteins
Ubiquitination
Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions
Popow, J., Arnhof, H., Bader, G., Berger, H., Ciulli, A., Covini, D., Dank, C., Gmaschitz, T., Greb, P., Karolyi-Özguer, J., Koegl, M., McConnell, D. B., Pearson, M., Rieger, M., Rinnenthal, J., Roessler, V., Schrenk, A., Spina, M., Steurer, S., Trainor, N. & 4 others, 14 Mar 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2508–2520 13 p.Research output: Contribution to journal › Article
Focal Adhesion Protein-Tyrosine Kinases
Proteolysis
Hepatocellular Carcinoma
Cell Line
Ubiquitin-Protein Ligases
Protein degradation for drug discovery
Ciulli, A. & Farnaby, W., 11 Jun 2019, In : Drug discovery today. Technologies. 31, p. 1-3 3 p.Research output: Contribution to journal › Article
Rapid and reversible knockdown of endogenously tagged endosomal proteins via an optimized HaloPROTAC degrader
Tovell, H., Testa, A., Maniaci, C., Zhou, H., Prescott, A., Macartney, T., Ciulli, A. & Alessi, D., 2019, In : ACS Chemical Biology. 14, 5, p. 882-892 11 p.Research output: Contribution to journal › Article
Open Access
File
Degradation
Clustered Regularly Interspaced Short Palindromic Repeats
Proteins
Ubiquitination
Phosphorylation
RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response
Frost, J., Ciulli, A. & Rocha, S., 29 Jan 2019, In : Wellcome Open Research. 4, p. 1-17 17 p., 17.Research output: Contribution to journal › Article
File
Prolyl Hydroxylases
Genes
RNA
Prolyl-Hydroxylase Inhibitors
Chemical activation
Thesis
A ‘bump-&-hole’ approach for engineering allele-selective inhibition of the BET bromodomains
Author: Runcie, A. C., 2019Supervisor: Ciulli, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
Fragment-based approaches to probe the surface of the VHL E3 ligase
Author: Castro, G., 2019Supervisor: Ciulli, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
Ligandability of protein-protein interactions and surfaces on Cullin RING E3 ubiquitin ligases
Author: Cardote, T. A. D. F., 2017Supervisor: Ciulli, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
Protein-Protein Interactions and Small Molecule Targeting of the Multisubunit SOCS2-EloBC-Cul5-Rbx2 E3 Ubiquitin Ligase
Author: Kung, W., 2018Supervisor: Ciulli, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
Small-molecule approaches to interrogate the druggability of the VHL E3 Cullin RING Ubiquitin Ligase
Author: Soares, P., 2018Supervisor: Ciulli, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy