Projects per year
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- 4 Similar Profiles
Ubiquitin-Protein Ligases
Medicine & Life Sciences
pantothenate synthetase
Medicine & Life Sciences
Proteolysis
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Ligands
Medicine & Life Sciences
Molecules
Chemical Compounds
Cullin Proteins
Medicine & Life Sciences
Mycobacterium tuberculosis
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2013 2022
Understanding the Molecular Details as the Basis of Epigenetic Readers Function (Fellowship)
Bortoluzzi, A. & Ciulli, A.
1/10/15 → 30/09/16
Project: Research
High Throughput Biolayer Interferometry at Dundee for Anti-Microbial and Interaction Studies
Birch, P., Ciulli, A., Fairlamb, A., Gray, D., Hunter, B., Owen-Hughes, T., Palmer, T., Ryan, R., Sargent, F., Stanley-Wall, N. & van Aalten, D.
Biotechnology and Biological Sciences Research Council
22/01/15 → 21/01/16
Project: Research
Research Output 2008 2019
Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs
Girardini, M., Maniaci, C., Hughes, S., Testa, A. & Ciulli, A., 22 Feb 2019, In : Bioorganic & Medicinal Chemistry. 14 p.Research output: Contribution to journal › Article
Open Access
Proteolysis
Ubiquitin-Protein Ligases
Degradation
Cullin Proteins
Ubiquitination
Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions
Popow, J., Arnhof, H., Bader, G., Berger, H., Ciulli, A., Covini, D., Dank, C., Gmaschitz, T., Greb, P., Karolyi-Özguer, J., Koegl, M., McConnell, D. B., Pearson, M., Rieger, M., Rinnenthal, J., Roessler, V., Schrenk, A., Spina, M., Steurer, S., Trainor, N. & 4 others, 14 Mar 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2508–2520 13 p.Research output: Contribution to journal › Article
Focal Adhesion Protein-Tyrosine Kinases
Proteolysis
Hepatocellular Carcinoma
Cell Line
Ubiquitin-Protein Ligases
RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response
Frost, J., Ciulli, A. & Rocha, S., 29 Jan 2019, In : Wellcome Open Research. 4, p. 1-17 17 p., 17.Research output: Contribution to journal › Article
File
Prolyl Hydroxylases
Genes
RNA
Prolyl-Hydroxylase Inhibitors
Chemical activation
SPR-measured dissociation kinetics of PROTAC ternary complexes influence target degradation rate
Roy, M., Winkler, S., Hughes, S. J., Whitworth, C., Galant, M., Farnaby, W., Rumpel, K. & Ciulli, A., 15 Mar 2019, In : ACS Chemical Biology. 14, 3, p. 361-368 8 p.Research output: Contribution to journal › Article
Open Access
File
Proteolysis
Enzyme kinetics
Degradation
Ubiquitin-Protein Ligases
Assays
Spy vs. Spy: Selecting the best reporter for 19F NMR competition experiment
Castro, G. V. D. & Ciulli, A., 4 Feb 2019, In : Chemical Communications. 55, 10, p. 1482-1485 4 p.Research output: Contribution to journal › Article
Open Access
File
Assays
Screening
Ligands
Nuclear magnetic resonance
Molecules
Thesis
A ‘bump-&-hole’ approach for engineering allele-selective inhibition of the BET bromodomains
Author: Runcie, A. C., 2019Supervisor: Ciulli, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
Ligandability of protein-protein interactions and surfaces on Cullin RING E3 ubiquitin ligases
Author: Cardote, T. A. D. F., 2017Supervisor: Ciulli, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
Protein-Protein Interactions and Small Molecule Targeting of the Multisubunit SOCS2-EloBC-Cul5-Rbx2 E3 Ubiquitin Ligase
Author: Kung, W., 2018Supervisor: Ciulli, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
Small-molecule approaches to interrogate the druggability of the VHL E3 Cullin RING Ubiquitin Ligase
Author: Soares, P., 2018Supervisor: Ciulli, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
Structural studies of paired PHD finger-bromodomain chromatin-binding modules: targeting epigenetic readers with chemical probes
Author: Amato, A., 2018Supervisor: Ciulli, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
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