Projects per year
Fingerprint Dive into the research topics where Alessio Ciulli is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 4 Similar Profiles
Ubiquitin-Protein Ligases
Medicine & Life Sciences
Proteolysis
Medicine & Life Sciences
pantothenate synthetase
Medicine & Life Sciences
Ligands
Medicine & Life Sciences
Molecules
Chemical Compounds
Proteins
Medicine & Life Sciences
Cullin Proteins
Medicine & Life Sciences
Mycobacterium tuberculosis
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2013 2022
Anchor E3s
Ciulli, A. & Lucas, X.
COMMISSION OF THE EUROPEAN COMMUNITIES
1/08/16 → 31/07/18
Project: Research
Understanding the Molecular Details as the Basis of Epigenetic Readers Function (Fellowship)
Bortoluzzi, A. & Ciulli, A.
1/10/15 → 30/09/16
Project: Research
High Throughput Biolayer Interferometry at Dundee for Anti-Microbial and Interaction Studies
Birch, P., Ciulli, A., Fairlamb, A., Gray, D., Hunter, B., Owen-Hughes, T., Palmer, T., Ryan, R., Sargent, F., Stanley-Wall, N. & van Aalten, D.
Biotechnology and Biological Sciences Research Council
22/01/15 → 21/01/16
Project: Research
Research Output 2008 2019
17
Citations
(Scopus)
17
Downloads
(Pure)
BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
Farnaby, W., Koegl, M., Roy, M. J., Whitworth, C., Diers, E., Trainor, N., Zollman, D., Steurer, S., Karolyi-Oezguer, J., Riedmueller, C., Gmaschitz, T., Wachter, J., Dank, C., Galant, M., Sharps, B., Rumpel, K., Traxler, E., Gerstberger, T., Schnitzer, R., Petermann, O. & 17 others, , Jul 2019, In : Nature Chemical Biology. 15, 7, p. 672-680 9 p.Research output: Contribution to journal › Article
Open Access
File
Proteolysis
Adenosine Triphosphatases
Biophysics
Neoplasms
Chromatin Assembly and Disassembly
1
Citation
(Scopus)
Bifunctional chemical probes inducing protein-protein interactions
Maniaci, C. & Ciulli, A., Oct 2019, In : Current Opinion in Chemical Biology. 52, p. 145-156 12 p.Research output: Contribution to journal › Review article
Ubiquitin-Protein Ligases
Adhesives
Proteolysis
Ligands
Molecular recognition
5
Citations
(Scopus)
Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs
Girardini, M., Maniaci, C., Hughes, S., Testa, A. & Ciulli, A., 15 Jun 2019, In : Bioorganic & Medicinal Chemistry. 27, 12, p. 2466-2479 14 p.Research output: Contribution to journal › Article
Open Access
Proteolysis
Ubiquitin-Protein Ligases
Degradation
Cullin Proteins
Ubiquitination
1
Citation
(Scopus)
49
Downloads
(Pure)
Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader
Tovell, H., Testa, A., Zhou, H., Shpiro, N., Crafter, C., Ciulli, A. & Alessi, D., 20 Sep 2019, In : ACS Chemical Biology. 14, 9, p. 2024-2034 11 p.Research output: Contribution to journal › Article
Open Access
File
Phosphatidylinositol 3-Kinases
Protein Isoforms
Phosphotransferases
Cells
Degradation
6
Citations
(Scopus)
Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions
Popow, J., Arnhof, H., Bader, G., Berger, H., Ciulli, A., Covini, D., Dank, C., Gmaschitz, T., Greb, P., Karolyi-Özguer, J., Koegl, M., McConnell, D. B., Pearson, M., Rieger, M., Rinnenthal, J., Roessler, V., Schrenk, A., Spina, M., Steurer, S., Trainor, N. & 4 others, , 14 Mar 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2508–2520 13 p.Research output: Contribution to journal › Article
Focal Adhesion Protein-Tyrosine Kinases
Proteolysis
Hepatocellular Carcinoma
Cell Line
Ubiquitin-Protein Ligases
Thesis
A ‘bump-&-hole’ approach for engineering allele-selective inhibition of the BET bromodomains
Author: Runcie, A. C., 2019Supervisor: Ciulli, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
Discovery of high quality molecular leads and screening collections for CNS drug targets
Author: Farnaby, W., 2019Supervisor: Ciulli, A. (Supervisor) & Read, K. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
Fragment-based approaches to probe the surface of the VHL E3 ligase
Author: Castro, G., 2019Supervisor: Ciulli, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
Ligandability of protein-protein interactions and surfaces on Cullin RING E3 ubiquitin ligases
Author: Cardote, T. A. D. F., 2017Supervisor: Ciulli, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
Protein-Protein Interactions and Small Molecule Targeting of the Multisubunit SOCS2-EloBC-Cul5-Rbx2 E3 Ubiquitin Ligase
Author: Kung, W., 2018Supervisor: Ciulli, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy