If you made any changes in Pure these will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 4 Similar Profiles
Ubiquitin-Protein Ligases Medicine & Life Sciences
pantothenate synthetase Medicine & Life Sciences
Proteolysis Medicine & Life Sciences
Proteins Medicine & Life Sciences
Ligands Medicine & Life Sciences
Molecules Chemical Compounds
Cullin Proteins Medicine & Life Sciences
Mycobacterium tuberculosis Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2022

Research Output 2008 2019

Open Access
Proteolysis
Ubiquitin-Protein Ligases
Degradation
Cullin Proteins
Ubiquitination

Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions

Popow, J., Arnhof, H., Bader, G., Berger, H., Ciulli, A., Covini, D., Dank, C., Gmaschitz, T., Greb, P., Karolyi-Özguer, J., Koegl, M., McConnell, D. B., Pearson, M., Rieger, M., Rinnenthal, J., Roessler, V., Schrenk, A., Spina, M., Steurer, S., Trainor, N. & 4 othersTraxler, E., Wieshofer, C., Zoephel, A. & Ettmayer, P., 14 Mar 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2508–2520 13 p.

Research output: Contribution to journalArticle

Focal Adhesion Protein-Tyrosine Kinases
Proteolysis
Hepatocellular Carcinoma
Cell Line
Ubiquitin-Protein Ligases
3 Downloads (Pure)

RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response

Frost, J., Ciulli, A. & Rocha, S., 29 Jan 2019, In : Wellcome Open Research. 4, p. 1-17 17 p., 17.

Research output: Contribution to journalArticle

File
Prolyl Hydroxylases
Genes
RNA
Prolyl-Hydroxylase Inhibitors
Chemical activation
3 Downloads (Pure)

SPR-measured dissociation kinetics of PROTAC ternary complexes influence target degradation rate

Roy, M., Winkler, S., Hughes, S. J., Whitworth, C., Galant, M., Farnaby, W., Rumpel, K. & Ciulli, A., 15 Mar 2019, In : ACS Chemical Biology. 14, 3, p. 361-368 8 p.

Research output: Contribution to journalArticle

Open Access
File
Proteolysis
Enzyme kinetics
Degradation
Ubiquitin-Protein Ligases
Assays
9 Downloads (Pure)

Spy vs. Spy: Selecting the best reporter for 19F NMR competition experiment

Castro, G. V. D. & Ciulli, A., 4 Feb 2019, In : Chemical Communications. 55, 10, p. 1482-1485 4 p.

Research output: Contribution to journalArticle

Open Access
File
Assays
Screening
Ligands
Nuclear magnetic resonance
Molecules

Thesis

A ‘bump-&-hole’ approach for engineering allele-selective inhibition of the BET bromodomains

Author: Runcie, A. C., 2019

Supervisor: Ciulli, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Ligandability of protein-protein interactions and surfaces on Cullin RING E3 ubiquitin ligases

Author: Cardote, T. A. D. F., 2017

Supervisor: Ciulli, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Protein-Protein Interactions and Small Molecule Targeting of the Multisubunit SOCS2-EloBC-Cul5-Rbx2 E3 Ubiquitin Ligase

Author: Kung, W., 2018

Supervisor: Ciulli, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Small-molecule approaches to interrogate the druggability of the VHL E3 Cullin RING Ubiquitin Ligase

Author: Soares, P., 2018

Supervisor: Ciulli, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Structural studies of paired PHD finger-bromodomain chromatin-binding modules: targeting epigenetic readers with chemical probes

Author: Amato, A., 2018

Supervisor: Ciulli, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File