Ciulli, Alessio

Professor

Professor & Personal Chair of Chemical and Structural Biology, Biological Chemistry and Drug Discovery

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1 Not started
2 Active
8 Finished

EUbOPEN: Enabling and Unlocking biology in the OPEN (Joint with Goethe University Frankfurt, University of Oxford, Karolinska Institute and 9 others)
Ciulli, A.
COMMISSION OF THE EUROPEAN COMMUNITIES
1/05/20 → 30/04/25
Project: Research
Novel PROTAC-based Chemical Biology Approaches to Induced Protein Knockdown Across the Proteome (PhD Studentship - with Boehringer Ingelheim)
Ciulli, A. & Sapkota, G.
3/09/18 → 2/09/22
Project: Research
Targeting E3 ubiquitin lifases with sall molecules (iCASE) Student - Thomas Webb
Ciulli, A. & Virdee, S.
Project: Research
Anchor E3s
Ciulli, A. & Lucas, X.
COMMISSION OF THE EUROPEAN COMMUNITIES
1/08/16 → 31/07/18
Project: Research
Understanding the Molecular Details as the Basis of Epigenetic Readers Function (Fellowship)
Bortoluzzi, A. & Ciulli, A.
1/10/15 → 30/09/16
Project: Research

65 Article
8 Review article
2 Chapter
1 Chapter (peer-reviewed)
More

Building ubiquitination machineries: E3 ligase multi-subunit assembly and substrate targeting by PROTACs and molecular glues
Ramachandran, S. & Ciulli, A., Apr 2021, In: Current Opinion in Structural Biology. 67, p. 110-119 10 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
33 Downloads (Pure)
Recent advances in synthetic and medicinal chemistry of phosphotyrosine and phosphonate-based phosphotyrosine analogues
Makukhin, N. & Ciulli, A., Jan 2021, In: RSC Medicinal Chemistry. 12, 1, p. 8-23 16 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
1 Citation (Scopus)

4 Downloads (Pure)
Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma
Pietrobono, S., Gaudio, E., Gagliardi, S., Zitani, M., Carrassa, L., Migliorini, F., Petricci, E., Manetti, F., Makukhin, N., Bond, A. G., Paradise, B. D., Ciulli, A., Fernandez-Zapico, M. E., Bertoni, F. & Stecca, B., 6 May 2021, (E-pub ahead of print) In: Oncogene. 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Transforming targeted cancer therapy with PROTACs: A forward-looking perspective
Farnaby, W., Koegl, M., McConnell, D. B. & Ciulli, A., Apr 2021, In: Current Opinion in Pharmacology. 57, p. 175-183 9 p.
Research output: Contribution to journal › Review article › peer-review
E3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New Ones
Ishida, T. & Ciulli, A., 3 Nov 2020, (E-pub ahead of print) SLAS Discovery 19 p.
Research output: Contribution to specialist publication › Article

Open Access
File
3 Citations (Scopus)

22 Downloads (Pure)