Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Network
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DCAF E3 Ligase Exploration To Expand degRadation (DELETER)
COMMISSION OF THE EUROPEAN COMMUNITIES
1/05/21 → 30/04/23
Project: Research
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PROTACT Linker Design: towards Functionality (PREDICT)
COMMISSION OF THE EUROPEAN COMMUNITIES
1/05/21 → 30/06/23
Project: Research
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Breaking free from the crystal lattice: Structural biology in solution to study protein degraders
Haubrich, K., Spiteri, V., Farnaby, W., Sobott, F. & Ciulli, A., Apr 2023, In: Current Opinion in Structural Biology. 79, 9 p., 102534.Research output: Contribution to journal › Review article › peer-review
Open AccessFile4 Downloads (Pure) -
Crystallization of VHL-based PROTAC-induced ternary complexes
Wijaya, A. J., Farnaby, W. & Ciulli, A., 2023, Targeted Protein Degradation. Burslem, G. L. (ed.). Academic Press Inc., Vol. 681. p. 241-263 23 p. (Methods in Enzymology).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders
Hanzl, A., Casement, R., Imrichova, H., Hughes, S. J., Barone, E., Testa, A., Bauer, S., Wright, J., Brand, M., Ciulli, A. & Winter, G. E., Mar 2023, In: Nature Chemical Biology. 19, p. 323-333 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)160 Downloads (Pure) -
A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo
Kofink, C., Trainor, N., Mair, B., Wöhrle, S., Wurm, M., Mischerikow, N., Roy, M. J., Bader, G., Greb, P., Garavel, G., Diers, E., McLennan, R., Whitworth, C., Vetma, V., Rumpel, K., Scharnweber, M., Fuchs, J. E., Gerstberger, T., Cui, Y., Gremel, G., & 10 others , 10 Oct 2022, In: Nature Communications. 13, 15 p., 5969.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)23 Downloads (Pure) -
Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms
Grohmann, C., Magtoto, C. M., Walker, J. R., Chua, N. K., Gabrielyan, A., Hall, M., Cobbold, S. A., Mieruszynski, S., Brzozowski, M., Simpson, D. S., Dong, H., Dorizzi, B., Jacobsen, A. V., Morrish, E., Silke, N., Murphy, J. M., Heath, J. K., Testa, A., Maniaci, C., Ciulli, A., & 3 others , 19 Apr 2022, In: Nature Communications. 13, p. 1-13 13 p., 2073.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)11 Downloads (Pure)
Prizes
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EFMC Prize for Young Medicinal Chemist in Academia
Ciulli, Alessio (Recipient), 2015
Prize: Prize (including medals and awards)
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Fellow of the Royal Society of Chemistry (FRSC)
Ciulli, Alessio (Recipient), 2016
Prize: Election to learned society
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Fellow of the Royal Society of Edinburgh
Ciulli, Alessio (Recipient), 2023
Prize: Election to learned society
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ICBS Young Chemical Biologist Award
Ciulli, Alessio (Recipient), 2015
Prize: Prize (including medals and awards)
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MedChemComm Emerging Investigator Lectureship
Ciulli, Alessio (Recipient), 2016
Prize: Prize (including medals and awards)
Activities
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8th NovAliX Conference ‘Developing the Synergy between Biophysics and Medicinal Chemistry to Deliver Better Drugs’, Biophysics in Drug Discovery, Munich & virtual, May 9-11, 2022 (Event)
Alessio Ciulli (Member)
2022 → …Activity: Membership types › Membership of committee
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ChemMedChem (External organisation)
Alessio Ciulli (Member)
2021 → …Activity: Membership types › Membership of board
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Chemical Probes Portal (www.chemicalprobes.org) (External organisation)
Alessio Ciulli (Member)
2021 → …Activity: Membership types › Membership of board
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Chemical Society Reviews (Journal)
Alessio Ciulli (Guest editor) & Shaomeng Wang (Guest editor)
2021 → 2022Activity: Publication peer-review and editorial work types › Editorial activity
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6th EFMC-YSN MedChemBioOnline
Alessio Ciulli (Invited speaker)
28 Jan 2021Activity: Participating in or organising an event types › Participation in workshop, seminar, course
Press/Media
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£38 million investment in University spinout Amphista therapeutics
16/03/21 → 17/03/21
1 item of Media coverage, 2 Media contributions
Press/Media: Other
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Marie Skłodowska-Curie Fellowship Success for School
10/03/21
1 Media contribution
Press/Media: Research