Ciulli, Alessio

Farnaby, W., Koegl, M., Roy, M. J., Whitworth, C., Diers, E., Trainor, N., Zollman, D., Steurer, S., Karolyi-Oezguer, J., Riedmueller, C., Gmaschitz, T., Wachter, J., Dank, C., Galant, M., Sharps, B., Rumpel, K., Traxler, E., Gerstberger, T., Schnitzer, R., Petermann, O. & 17 others, Greb, P., Weinstabl, H., Bader, G., Zoephel, A., Weiss-Puxbaum, A., Ehrenhöfer-Wölfer, K., Wöhrle, S., Boehmelt, G., Rinnenthal, J., Arnhof, H., Wiechens, N., Wu, M-Y., Owen-Hughes, T., Ettmayer, P., Pearson, M., McConnell, D. B. & Ciulli, A., Jul 2019, In : Nature Chemical Biology. 15, 7, p. 672-680 9 p.

Research output: Contribution to journal › Article

Proteolysis

Adenosine Triphosphatases

Biophysics

Neoplasms

Chromatin Assembly and Disassembly

Bifunctional chemical probes inducing protein-protein interactions

Maniaci, C. & Ciulli, A., Oct 2019, In : Current Opinion in Chemical Biology. 52, p. 145-156 12 p.

Research output: Contribution to journal › Review article

Proteins

Ubiquitin-Protein Ligases

Molecules

Glues

Adhesives

2 Citations (Scopus)

Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs

Girardini, M., Maniaci, C., Hughes, S., Testa, A. & Ciulli, A., 15 Jun 2019, In : Bioorganic & Medicinal Chemistry. 27, 12, p. 2466-2479 14 p.

Research output: Contribution to journal › Article

Open Access

Proteolysis

Ubiquitin-Protein Ligases

Degradation

Cullin Proteins

Ubiquitination

27 Downloads (Pure)

Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader

Tovell, H., Testa, A., Zhou, H., Shpiro, N., Crafter, C., Ciulli, A. & Alessi, D., 20 Sep 2019, In : ACS Chemical Biology. 14, 9, p. 2024-2034 11 p.

Research output: Contribution to journal › Article

Open Access

File

Phosphatidylinositol 3-Kinases

Protein Isoforms

Phosphotransferases

Cells

Degradation

4 Citations (Scopus)

Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions

Popow, J., Arnhof, H., Bader, G., Berger, H., Ciulli, A., Covini, D., Dank, C., Gmaschitz, T., Greb, P., Karolyi-Özguer, J., Koegl, M., McConnell, D. B., Pearson, M., Rieger, M., Rinnenthal, J., Roessler, V., Schrenk, A., Spina, M., Steurer, S., Trainor, N. & 4 others, Traxler, E., Wieshofer, C., Zoephel, A. & Ettmayer, P., 14 Mar 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2508–2520 13 p.

Research output: Contribution to journal › Article

Focal Adhesion Protein-Tyrosine Kinases

Proteolysis

Hepatocellular Carcinoma

Cell Line

Ubiquitin-Protein Ligases