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Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 5 Similar Profiles
Ubiquitin-Protein Ligases Medicine & Life Sciences
pantothenate synthetase Medicine & Life Sciences
Ligands Medicine & Life Sciences
Proteins Medicine & Life Sciences
Molecules Chemical Compounds
Mycobacterium tuberculosis Medicine & Life Sciences
Proteolysis Medicine & Life Sciences
Cullin Proteins Medicine & Life Sciences

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Research Output 2008 2018

1 Citations

3-Fluoro-4-hydroxyprolines: Synthesis, conformational analysis and stereoselective recognition by the VHL E3 ubiquitin ligase for targeted protein degradation

Testa, A., Lucas, X., Castro, G., Chan, K. H., Wright, J., Runcie, A., Gadd, M., Harrison, W. T. A., Ko, E. J., Fletcher, D. & Ciulli, A., 25 Jul 2018, In : Journal of the American Chemical Society. 140, 29, p. 9299-9313 15 p.

Research output: Contribution to journalArticle

Open Access
File
Hydroxyproline
Ubiquitin-Protein Ligases
Proteolysis
Proteins
Degradation
18 Citations
Open Access
File
WEB 2086
Proteolysis
Ligands
Ubiquitin-Protein Ligases
Myeloid Cells
3 Citations

Optimization of a “Bump-and-Hole” Approach to Allele-Selective BET Bromodomain Inhibition

Runcie, A., Zengerle, M., Chan, K. H., Testa, A., Van Beurden, L., Baud, M., Epemolu, R., Ellis, L., Read, K., Coulthard, V., Brien, A. & Ciulli, A., 9 Mar 2018, In : Chemical Science. 2018, 9, p. 2387-2634 18 p., 2452.

Research output: Contribution to journalArticle

Open Access
File
Benzodiazepines
Leucine
Proteins
Cell proliferation
Valine
Ubiquitin-Protein Ligases
Proteins
Homeostasis
X-Rays
Ligands
1 Citations

Targeting ligandable pockets on PHD zinc finger domains by a fragment-based approach

Amato, A., Lucas, X., Bortoluzzi, A., Wright, D. & Ciulli, A., 20 Apr 2018, In : ACS Chemical Biology. 13, 4, p. 915-921 7 p.

Research output: Contribution to journalArticle

Open Access
File
Zinc Fingers
Histones
Zinc
Homeodomain Proteins
Plant Structures

Thesis

Ligandability of protein-protein interactions and surfaces on Cullin RING E3 ubiquitin ligases

Author: Cardote, T. A. D. F., 2017

Supervisor: Ciulli, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Protein-Protein Interactions and Small Molecule Targeting of the Multisubunit SOCS2-EloBC-Cul5-Rbx2 E3 Ubiquitin Ligase

Author: Kung, W., 2018

Supervisor: Ciulli, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Small-molecule approaches to interrogate the druggability of the VHL E3 Cullin RING Ubiquitin Ligase

Author: Soares, P., 2018

Supervisor: Ciulli, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Structural studies of paired PHD finger-bromodomain chromatin-binding modules: targeting epigenetic readers with chemical probes

Author: Amato, A., 2018

Supervisor: Ciulli, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

VHL inhibitors as chemical probes of the hypoxia signalling pathway

Author: Frost, J., 2018

Supervisor: Ciulli, A. (Supervisor) & Rocha, S. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy