Keyphrases
Proteolysis Targeting chimera (PROTAC)
100%
Degrader
60%
E3 Ligase
42%
E3 Ubiquitin Ligase
40%
Small Molecules
38%
Bromodomain
37%
Von Hippel-Lindau
36%
Ternary Complex
32%
Chemical Probes
27%
Targeted Protein Degradation
24%
Bromodomain-containing Protein 4 (BRD4)
21%
Mycobacterium Tuberculosis (M. tb)
20%
Protein Degradation
19%
Fragment Screening
17%
Protein-protein Interaction
17%
Small Molecule Inhibitors
16%
Protein Degraders
15%
Structure-based Design
15%
Hypoxia-inducible factor-1α (HIF-1α)
14%
Medicinal Chemistry
14%
Ligase
13%
Bromo
13%
Protein Binding
12%
Pantothenate Synthetase
12%
Ubiquitination
12%
Drug Discovery
11%
Bifunctional Molecules
11%
Chemical Biology
11%
Cullin-RING E3 Ligase
11%
SMARCA4
10%
Cooperativity
10%
Linker
9%
In Cancer
9%
Targeted Degradation
9%
Binding Affinity
9%
Von Hippel-Lindau Disease
8%
Potent Inhibitor
8%
Cereblon
8%
Bump
8%
Fragment-based Approach
8%
SMARCA2
8%
Fragment-based Drug Discovery
8%
X-ray Crystallography
8%
Binding Site
7%
Biophysical Studies
7%
PROTAC Degraders
7%
Molecular Glue
7%
Target Molecule
7%
19F NMR
7%
Displacement Assay
7%
Biochemistry, Genetics and Molecular Biology
Protein Catabolism
99%
Small Molecule
64%
Ligase
57%
Ubiquitin-Conjugating Enzyme
52%
Bromodomain
45%
Ternary Complex
35%
Ubiquitination
21%
Crystal Structure
20%
Enzyme
18%
Protein-Protein Interaction
16%
Mycobacterium Tuberculosis
15%
Cullin
14%
Pantothenic Acid
13%
Binding Protein
12%
BRD4
12%
X-Ray Crystallography
11%
Histone
10%
Hypoxia-Inducible Factors
10%
Epigenetics
10%
SMARCA4
10%
Proteolysis
10%
Ubiquitin
9%
Binding Affinity
9%
Isothermal Titration Calorimetry
9%
Hypoxia Inducible Factor 1
9%
Cooperation
9%
Isoform
9%
Molecular Recognition
8%
Ubiquitin Ligase
8%
Cereblon
8%
Solution and Solubility
8%
Posttranslational Modification
7%
Chromatin Remodeling
7%
Cytokine
7%
Targeting Protein
7%
Proteasome
7%
Conformation
7%
SMARCA2
7%
Ligand Binding
6%
Binding Site
6%
Biological Functions
6%
Proteome
6%
Structure Activity Relation
6%
Magnetism
6%
X Ray
6%
Elongin
6%
Chemical Genetics
5%
Complex Formation
5%
Procollagen-Proline Dioxygenase
5%
Signal Transduction
5%