Keyphrases
Proteolysis Targeting chimera (PROTAC)
100%
Degrader
53%
E3 Ubiquitin Ligase
37%
E3 Ligase
37%
Von Hippel-Lindau
36%
Small Molecules
36%
Bromodomain
35%
Ternary Complex
29%
Chemical Probes
27%
Targeted Protein Degradation
24%
Bromodomain-containing Protein 4 (BRD4)
20%
Mycobacterium Tuberculosis (M. tb)
19%
Protein-protein Interaction
16%
Fragment Screening
15%
Protein Degradation
15%
Small Molecule Inhibitors
15%
Structure-based Design
14%
Hypoxia-inducible factor-1α (HIF-1α)
13%
Medicinal Chemistry
13%
Bromo
12%
Ubiquitination
12%
Protein Degraders
12%
Protein Binding
12%
Pantothenate Synthetase
11%
Drug Discovery
11%
Bifunctional Molecules
11%
In Cancer
10%
Chemical Biology
10%
Cullin-RING E3 Ligase
10%
Linker
10%
Ligase
10%
SMARCA4
10%
Cooperativity
9%
Targeted Degradation
9%
Druggability
8%
Binding Affinity
8%
Von Hippel-Lindau Disease
8%
Potent Inhibitor
8%
Bump
7%
Fragment-based Approach
7%
SMARCA2
7%
Fragment-based Drug Discovery
7%
X-ray Crystallography
7%
PROTAC Degraders
7%
Target Molecule
7%
19F NMR
7%
Displacement Assay
7%
Suppressor of Cytokine Signaling 2
7%
Binding Site
6%
Knockdown
6%
Biochemistry, Genetics and Molecular Biology
Proteolysis
80%
Small Molecule
63%
Ubiquitin Ligase
59%
Ubiquitin-Conjugating Enzyme
46%
Bromodomain
42%
Protein Catabolism
41%
Ternary Complex
33%
Ubiquitination
22%
Crystal Structure
19%
Enzyme
17%
Protein-Protein Interaction
15%
Mycobacterium Tuberculosis
14%
Cullin
13%
Pantothenic Acid
12%
BRD4
12%
Binding Protein
12%
Ligase
11%
X-Ray Crystallography
10%
Cytokine
10%
Histone
9%
Molecular Glue
9%
Hypoxia-Inducible Factors
9%
Epigenetics
9%
Ubiquitin
9%
SMARCA4
9%
Cooperation
8%
Isothermal Titration Calorimetry
8%
Hypoxia Inducible Factor 1
8%
Binding Affinity
8%
Isoform
8%
Molecular Recognition
8%
Solution and Solubility
8%
Targeting Protein
7%
Conformation
7%
Posttranslational Modification
7%
Chromatin Remodeling
7%
Proteome
7%
Proteasome
6%
Nuclear Magnetic Resonance Spectroscopy
6%
SMARCA2
6%
Biological Functions
6%
Ligand Binding
6%
Binding Site
6%
Cancer Cell
5%
X Ray
5%
Complex Formation
5%
Cereblon
5%
Elongin
5%
Chemical Genetics
5%
Structure Activity Relation
5%
