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Research Output 1995 2018

  • 4112 Citations
  • 29 h-Index
  • 45 Article
  • 2 Letter
  • 1 Chapter (peer-reviewed)
  • 1 Comment/debate

Cell-Free Assays to Measure Effects of Regulatory Ligands on AMPK

Fyffe, F. A., Hawley, S. A., Gray, A. & Hardie, D. G., 2018, AMPK : Methods and Protocols. Neumann, D. & Viollet, B. (eds.). Humana Press, p. 69-86 18 p. (Methods in Molecular Biology; vol. 1732)

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

AMP-Activated Protein Kinases
Adenosine Triphosphate
Adenosine Monophosphate
Ligands
Adenosine Diphosphate

Genotoxic Damage Activates the AMPK-α1 Isoform in the Nucleus via Ca2+/CaMKK2 Signaling to Enhance Tumor Cell Survival

Vara Ciruelos, D., Dandapani, M., Gray, A., Agbani, E. O., Evans, A. M. & Hardie, D. G., Feb 2018, In : Molecular Cancer Research. 16, 2, p. 345-357 13 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Cell Survival
Protein Isoforms
Etoposide
DNA Damage

Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity

Thomas, E. C., Hook, S. C., Gray, A., Chadt, A., Carling, D., Al-Hasani, H., Heesom, K. J., Hardie, D. G. & Tavaré, J. M., 25 Sep 2018, In : The Biochemical journal. 475, 18, p. 2969-2983 35 p.

Research output: Contribution to journalArticle

Open Access
File
AMP-Activated Protein Kinases
Morbid Obesity
Protein Isoforms
Phosphorylation
Association reactions
2 Citations

A novel, de novo mutation in PRKAG2 gene: infantile-onset phenotype and signaling pathway involved

Xu, Y., Gray, A., Hardie, D. G., Uzun, A., Shaw, S., Padbury, J., Phornphutkul, C. & Tseng, Y-T., 1 Aug 2017, In : American Journal of Physiology: Heart and Circulatory Physiology. 313, 2, p. H283-H292 10 p.

Research output: Contribution to journalArticle

Open Access
File
Phenotype
Mutation
AMP-Activated Protein Kinases
Genes
Hypertrophic Cardiomyopathy
39 Citations

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

Zhang, C-S., Hawley, S. A., Zong, Y., Li, M., Wang, Z., Gray, A., Ma, T., Cui, J., Feng, J-W., Zhu, M., Wu, Y-Q., Li, T. Y., Ye, Z., Lin, S-Y., Yin, H., Piao, H-L., Hardie, D. G. & Lin, S-C., 3 Aug 2017, In : Nature. 548, 7665, p. 112-116 23 p.

Research output: Contribution to journalLetter

Open Access
File
Fructose-Bisphosphate Aldolase
AMP-Activated Protein Kinases
Glucose
Adenosine Monophosphate
Adenosine Diphosphate