• 5004 Citations
  • 33 h-Index
19952018
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Personal profile

Biography

Dr Alexander Gray Bsc PhD Born in Scotland educated at the University of Edinburgh PhD 1987, worked as a post doc at University of Edinburgh, University of Glasgow Welcome unit of Molecular Parasitology, Roslin Research Institute and the University of Dundee. In my current position as Principal Investigator in the Leverhulme Research Centre for Forensic Science I am focusing on forensic DNA techniques as my main research interests in the past have centred around molecular biology, specifically DNA manipulation methods and biochemistry related to cellular signalling.

 

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Research Output 1995 2018

  • 5004 Citations
  • 33 h-Index
  • 45 Article
  • 2 Comment/debate
  • 2 Letter
  • 1 Chapter (peer-reviewed)
1 Citation (Scopus)

Cell-Free Assays to Measure Effects of Regulatory Ligands on AMPK

Fyffe, F. A., Hawley, S. A., Gray, A. & Hardie, D. G., 2018, AMPK : Methods and Protocols. Neumann, D. & Viollet, B. (eds.). New York: Humana Press, p. 69-86 18 p. (Methods in Molecular Biology; vol. 1732).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

AMP-Activated Protein Kinases
Adenosine Triphosphate
Adenosine Monophosphate
Ligands
Adenosine Diphosphate
8 Citations (Scopus)
50 Downloads (Pure)

Genotoxic Damage Activates the AMPK-α1 Isoform in the Nucleus via Ca2+/CaMKK2 Signaling to Enhance Tumor Cell Survival

Vara Ciruelos, D., Dandapani, M., Gray, A., Agbani, E. O., Evans, A. M. & Hardie, D. G., Feb 2018, In : Molecular Cancer Research. 16, 2, p. 345-357 13 p.

Research output: Contribution to journalArticle

Open Access
File
AMP-Activated Protein Kinases
Cell Survival
Protein Isoforms
Etoposide
DNA Damage
4 Citations (Scopus)
55 Downloads (Pure)

Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity

Thomas, E. C., Hook, S. C., Gray, A., Chadt, A., Carling, D., Al-Hasani, H., Heesom, K. J., Hardie, D. G. & Tavaré, J. M., 25 Sep 2018, In : The Biochemical journal. 475, 18, p. 2969-2983 35 p.

Research output: Contribution to journalArticle

Open Access
File
AMP-Activated Protein Kinases
Morbid Obesity
Protein Isoforms
Phosphorylation
Association reactions
2 Citations (Scopus)
99 Downloads (Pure)

A novel, de novo mutation in PRKAG2 gene: infantile-onset phenotype and signaling pathway involved

Xu, Y., Gray, A., Hardie, D. G., Uzun, A., Shaw, S., Padbury, J., Phornphutkul, C. & Tseng, Y-T., 1 Aug 2017, In : American Journal of Physiology: Heart and Circulatory Physiology. 313, 2, p. H283-H292 10 p.

Research output: Contribution to journalArticle

Open Access
File
Phenotype
Mutation
AMP-Activated Protein Kinases
Genes
Hypertrophic Cardiomyopathy
100 Citations (Scopus)
96 Downloads (Pure)

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

Zhang, C-S., Hawley, S. A., Zong, Y., Li, M., Wang, Z., Gray, A., Ma, T., Cui, J., Feng, J-W., Zhu, M., Wu, Y-Q., Li, T. Y., Ye, Z., Lin, S-Y., Yin, H., Piao, H-L., Hardie, D. G. & Lin, S-C., 3 Aug 2017, In : Nature. 548, 7665, p. 112-116 23 p.

Research output: Contribution to journalLetter

Open Access
File
Fructose-Bisphosphate Aldolase
AMP-Activated Protein Kinases
Glucose
Adenosine Monophosphate
Adenosine Diphosphate

Activities 2018 2019

  • 1 Festival/Exhibition
  • 1 Public engagement and outreach - public lecture/debate/seminar

Crime Cafe: Does DNA always hold the answer?

Alexander Gray (Presenter), Heather Doran (Host), Alex Prentice (Presenter)
14 May 2019

Activity: Other activity typesPublic engagement and outreach - public lecture/debate/seminar

File

Glasgow Science Centre, Citizen Forensic Science

Herve Menard (Contributor), Alexander Gray (Contributor), Aga Kuffel (Contributor), Roy Mudie (Contributor), Lysbeth Antonides (Contributor), Catarina Sobreira (Contributor)
11 Oct 2018

Activity: Participating in or organising an event typesFestival/Exhibition

Press / Media

Crime Cafe Dundee 2019

Heather Doran, Lucina Hackman, Alexander Gray, Herve Menard & Niamh Nic Daeid

15/03/1916/03/19

2 items of Media coverage

Press/Media: Other