Projects per year
Personal profile
Biography
Professor Amelia Shoemark is Asthma and Lung UK Chair of Respiratory Research at the University of Dundee, where she conducts a translational research program in chronic respiratory disease with Prof James Chalmers
Amelia began her career as an NHS clinical scientist at the Royal Brompton Hospital in London. She set up and led a nationally funded laboratory for the diagnosis of Primary Ciliary Dyskinesia (PCD) from 2007-2017, a position she still holds part time. Her translational research interests, funded by a personal post-doctoral fellowship from the National Institute of Health Research (NIHR) brought new reliable and affordable tests for PCD with improved diagnostic sensitivity. Along with international collaborators she was instrumental in identification of several of the genes now known to cause PCD. She is currently Chair of the BEAT-PCD European Respiratory Society clinical research consortium and chair of the joint ERS/ATS diagnostic guideline committee.
Professor Shoemark completed her PhD at Imperial college in 2010 investigating inflammation in the chronic respiratory condition bronchiectasis. She moved to University of Dundee in 2017 to work in the laboratories of Professor Chalmers to set up EMBARC BRIDGE, an international bronchiectasis endotyping study which has described several aspects of the pathophysiology of the disease leading to identification of targets for new therapies. She is an active member of the EMBARC management committee.
These translational areas of respiratory research have led to>100 peer review articles and book chapters on bronchiectasis, primary ciliary dyskinesia and mucociliary clearance. She enthusiastically supervises and mentors undergraduate and post graduate scientists and clinicians.
Research
The respiratory research group aims to develop new treatments for acute and chronic lung diseases through experimental medicine, the translation of scientific discoveries into patient benefit.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Targeting Cilia Dysfunction As A Therapeutic Strategy For Bronchiectasis
Shoemark, A. (Investigator)
1/10/22 → 30/09/27
Project: Research
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Is Neutrophil Inflammatory Phenotype Regulated By Olfactomedin-4 In Bronchiectasis (Clinical Academic Fellowship)
Chalmers, J. (Investigator) & Shoemark, A. (Investigator)
1/04/22 → 31/03/25
Project: Research
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ACE2 Receptor in Nasal Ciliated Epithelial Cells as a Therapeutic Target for COVID19
Connell, D. (Investigator) & Shoemark, A. (Investigator)
1/06/20 → 30/11/20
Project: Research
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Rapid Research in Covid -19 Programme
Barrable, A. (Investigator), Belch, J. (Investigator), Boehnke, J. (Investigator), Booth, D. (Investigator), Brown, A. (Investigator), Cantrell, D. (Investigator), Chalmers, J. (Investigator), Coleman, S. (Investigator), Connell, D. (Investigator), Cuschieri, A. (Investigator), Dicker, A. (Investigator), Doney, A. (Investigator), Eftimie, R. (Investigator), Fang, M. (Investigator), Farre, A. (Investigator), Gamble, C. (Investigator), Howden, A. (Investigator), Krstajic, N. (Investigator), Lamond, A. (Investigator), Moraga Gonzalez, I. (Investigator), Palmer, C. (Investigator), Parcell, B. (Investigator), Pearson, E. (Investigator), Shoemark, A. (Investigator) & Sixsmith, J. (Investigator)
1/06/20 → 30/09/21
Project: Research
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Broad Immunomodulatory Effects of the Dipeptidyl-peptidase-1 Inhibitor Brensocatib in Bronchiectasis: Data from the Phase 2, Double-Blind, Placebo-controlled WILLOW Trial
Johnson, E. D., Long, M. B., Perea, L., Shih, V. H., Fernandez, C., Teper, A., Cipolla, D., McIntosh, E., Galloway, R., Eke, Z., Shuttleworth, M., Hull, R., Spinou, A., De Soyza, A., Ringshausen, F. C., Goeminne, P., Lorent, N., Haworth, C., Loebinger, M. R. & Blasi, F. & 9 others, , 12 Feb 2025, (E-pub ahead of print) In: American Journal of Respiratory and Critical Care Medicine.Research output: Contribution to journal › Article › peer-review
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Clinical Efficacy of Serum Antiglycopeptidolipid Core IgA Antibody Test for Screening Nontuberculous Mycobacterial Pulmonary Disease in Bronchiectasis: A European Multicenter Cohort Study
Choi, H., Hughes, C., Eke, Z., Shuttleworth, M., Shteinberg, M., Polverino, E., Goeminne, P. C., Welte, T., Blasi, F., Shoemark, A., Long, M. B., Aliberti, S., Haworth, C. S., Ringshausen, F. C., Loebinger, M. R., Lorent, N. & Chalmers, J. D. (Lead / Corresponding author), 8 May 2025, In: Chest. 167, 5, p. 1300-1310 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus) -
A BEAT-PCD consensus statement: a core outcome set for pulmonary disease interventions in primary ciliary dyskinesia
Kos, R., Goutaki, M., Kobbernagel, H. E., Rubbo, B., Shoemark, A., Aliberti, S., Altenburg, J., Anagnostopoulou, P., Athanazio, R. A., Beydon, N., Dell, S. D., Emiralioglu, N., Ferkol, T. W., Loebinger, M. R., Lorent, N., Maître, B., Marthin, J., Morgan, L. C., Nielsen, K. G. & Ringshausen, F. C. & 6 others, , 8 Jan 2024, In: ERJ Open Research. 10, 1, 11 p., 00115-2023.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)103 Downloads (Pure) -
Airway IL-1β is related to disease severity and mucociliary function in bronchiectasis
Perea, L., Bottier, M., Cant, E., Richardson, H., Dicker, A. J., Shuttleworth, M., Giam, Y. H., Abo-Leyah, H., Finch, S., Huang, J.T.-J., Shteinberg, M., Goeminne, P. C., Polverino, E., Altenburg, J., Blasi, F., Welte, T., Aliberti, S., Sibila, O., Chalmers, J. D. & Shoemark, A. (Lead / Corresponding author), Aug 2024, In: European Respiratory Journal. 64, 2, 2301966.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
Airway 'Resistotypes' and Clinical Outcomes in Bronchiectasis
Mac Aogáin, M., Xaverius Ivan, F., Jaggi, T. K., Richardson, H., Shoemark, A., Narayana, J. K., Dicker, A. J., Koh, M. S., Lee, K. C. H., Thun How, O., Poh, M. E., Chin, K. K., Hou, A. L. Y., Ser Hon, P., Low, T. B., Abisheganaden, J. A., Dimakou, K., Digalaki, A., Kosti, C. & Gkousiou, A. & 5 others, , 1 Jul 2024, In: American Journal of Respiratory and Critical Care Medicine. 210, 1, p. 47-62 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)346 Downloads (Pure)
Activities
- 1 Public engagement and outreach - work on advisory panels
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PCD support UK - Scottish working group
Shoemark, A. (Member)
2017 → …Activity: Other activity types › Public engagement and outreach - work on advisory panels