Testa, Andrea

Dr

  • 176 Citations
  • 5 h-Index
20172019
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  • 75 Similar Profiles
Proteolysis Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Degradation Chemical Compounds
WEB 2086 Medicine & Life Sciences
Ubiquitination Medicine & Life Sciences
Proteins Chemical Compounds
Ubiquitin-Conjugating Enzymes Medicine & Life Sciences
Small Molecule Libraries Medicine & Life Sciences

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Research Output 2017 2019

  • 176 Citations
  • 5 h-Index
  • 10 Article
Open Access
Proteolysis
Ubiquitin-Protein Ligases
Degradation
Cullin Proteins
Ubiquitination
8 Citations (Scopus)
23 Downloads (Pure)

3-Fluoro-4-hydroxyprolines: Synthesis, conformational analysis and stereoselective recognition by the VHL E3 ubiquitin ligase for targeted protein degradation

Testa, A., Lucas, X., Castro, G., Chan, K. H., Wright, J., Runcie, A., Gadd, M., Harrison, W. T. A., Ko, E. J., Fletcher, D. & Ciulli, A., 25 Jul 2018, In : Journal of the American Chemical Society. 140, 29, p. 9299-9313 15 p.

Research output: Contribution to journalArticle

Open Access
File
Hydroxyproline
Ubiquitin-Protein Ligases
Proteolysis
Proteins
Degradation
32 Citations (Scopus)
49 Downloads (Pure)
Open Access
File
WEB 2086
Proteolysis
Ligands
Ubiquitin-Protein Ligases
Myeloid Cells
6 Citations (Scopus)
53 Downloads (Pure)

Iterative design and optimization of initially inactive Proteolysis Targeting Chimeras (PROTACs) identify VZ185 as a potent, fast and selective von Hippel-Lindau (VHL)-based dual degrader probe of BRD9 and BRD7

Zoppi, V., Hughes, S. J., Maniaci, C., Testa, A., Gmaschitz, T., Wieshofer, C., Koegl, M., Riching, K. M., Daniels, D. L., Spallarossa, A. & Ciulli, A., 12 Dec 2018, In : Journal of Medicinal Chemistry. 28 p.

Research output: Contribution to journalArticle

Open Access
File
Ubiquitination
Ligases
Proteolysis
Chromatin Assembly and Disassembly
Ubiquitin-Protein Ligases
38 Downloads (Pure)

New molecular and therapeutic insights into canine diffuse large B cell lymphoma elucidates the role of the dog as a model for human disease

Aresu, L., Ferraresso, S., Marconato, L., Cascione, L., Napoli, S., Gaudio, E., Kwee, I., Tarantelli, C., Testa, A., Maniaci, C., Ciulli, A., Hillmann, P., Bohnacker, T., Wymann, M. P., Comazzi, S., Milan, M., Riondato, F., Dalla Rovere, G., Giantin, M., Giannuzzi, D. & 1 othersBertoni, F., 13 Dec 2018, In : Haematologica.

Research output: Contribution to journalArticle

Open Access
File