Testa, Andrea

Dr

  • 225 Citations
  • 5 h-Index
20172019
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Fingerprint Dive into the research topics where Andrea Testa is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 39 Similar Profiles
Proteolysis Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Degradation Chemical Compounds
WEB 2086 Medicine & Life Sciences
Ubiquitination Medicine & Life Sciences
Proteins Chemical Compounds
Ubiquitin-Conjugating Enzymes Medicine & Life Sciences
Small Molecule Libraries Medicine & Life Sciences

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Research Output 2017 2019

  • 225 Citations
  • 5 h-Index
  • 11 Article
1 Citation (Scopus)

Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs

Girardini, M., Maniaci, C., Hughes, S., Testa, A. & Ciulli, A., 15 Jun 2019, In : Bioorganic & Medicinal Chemistry. 27, 12, p. 2466-2479 14 p.

Research output: Contribution to journalArticle

Open Access
Proteolysis
Ubiquitin-Protein Ligases
Degradation
Cullin Proteins
Ubiquitination

Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader

Tovell, H., Testa, A., Zhou, H., Shpiro, N., Crafter, C., Ciulli, A. & Alessi, D., 28 Aug 2019, In : ACS Chemical Biology. 11 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinases
Protein Isoforms
Phosphotransferases
Cells
Degradation
1 Citation (Scopus)
68 Downloads (Pure)

Rapid and reversible knockdown of endogenously tagged endosomal proteins via an optimized HaloPROTAC degrader

Tovell, H., Testa, A., Maniaci, C., Zhou, H., Prescott, A., Macartney, T., Ciulli, A. & Alessi, D., 17 May 2019, In : ACS Chemical Biology. 14, 5, p. 882-892 11 p.

Research output: Contribution to journalArticle

Open Access
File
Degradation
Clustered Regularly Interspaced Short Palindromic Repeats
Proteins
Ubiquitination
Phosphorylation
11 Citations (Scopus)
59 Downloads (Pure)

3-Fluoro-4-hydroxyprolines: Synthesis, conformational analysis and stereoselective recognition by the VHL E3 ubiquitin ligase for targeted protein degradation

Testa, A., Lucas, X., Castro, G., Chan, K. H., Wright, J., Runcie, A., Gadd, M., Harrison, W. T. A., Ko, E. J., Fletcher, D. & Ciulli, A., 25 Jul 2018, In : Journal of the American Chemical Society. 140, 29, p. 9299-9313 15 p.

Research output: Contribution to journalArticle

Open Access
File
Hydroxyproline
Ubiquitin-Protein Ligases
Proteolysis
Proteins
Degradation
37 Citations (Scopus)
83 Downloads (Pure)
Open Access
File
WEB 2086
Proteolysis
Ligands
Ubiquitin-Protein Ligases
Myeloid Cells