• 348 Citations
  • 7 h-Index
20172019

Research output per year

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Research Output

  • 348 Citations
  • 7 h-Index
  • 12 Article

Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs

Girardini, M., Maniaci, C., Hughes, S., Testa, A. & Ciulli, A., 15 Jun 2019, In : Bioorganic & Medicinal Chemistry. 27, 12, p. 2466-2479 14 p.

Research output: Contribution to journalArticle

Open Access
  • 5 Citations (Scopus)

    Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader

    Tovell, H., Testa, A., Zhou, H., Shpiro, N., Crafter, C., Ciulli, A. & Alessi, D., 20 Sep 2019, In : ACS Chemical Biology. 14, 9, p. 2024-2034 11 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 3 Citations (Scopus)
    72 Downloads (Pure)

    Iterative design and optimization of initially inactive Proteolysis Targeting Chimeras (PROTACs) identify VZ185 as a potent, fast and selective von Hippel-Lindau (VHL)-based dual degrader probe of BRD9 and BRD7

    Zoppi, V., Hughes, S. J., Maniaci, C., Testa, A., Gmaschitz, T., Wieshofer, C., Koegl, M., Riching, K. M., Daniels, D. L., Spallarossa, A. & Ciulli, A., 24 Jan 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 699-726 28 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 30 Citations (Scopus)
    270 Downloads (Pure)

    Rapid and reversible knockdown of endogenously tagged endosomal proteins via an optimized HaloPROTAC degrader

    Tovell, H., Testa, A., Maniaci, C., Zhou, H., Prescott, A., Macartney, T., Ciulli, A. & Alessi, D., 17 May 2019, In : ACS Chemical Biology. 14, 5, p. 882-892 11 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 4 Citations (Scopus)
    142 Downloads (Pure)

    Structure-Based Design of a Macrocyclic PROTAC

    Testa, A., Hughes, S. J., Lucas, X., Wright, J. E. & Ciulli, A., 19 Nov 2019, In : Angewandte Chemie International Edition. 9 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 43 Downloads (Pure)