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Personal profile

Education/Academic qualification

Doctor of Philosophy

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Protons Medicine & Life Sciences
Spontaneous emission Chemical Compounds
Pumps Chemical Compounds
spontaneous emission Physics & Astronomy
Electron Transport Complex IV Medicine & Life Sciences
Molecular Dynamics Simulation Medicine & Life Sciences
Static Electricity Medicine & Life Sciences
pulses Physics & Astronomy

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Research Output 2000 2019

10 Downloads (Pure)

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Baragaña, B., Forte, B., Choi, R., Nakazawa Hewitt, S., Bueren-Calabuig, J. A., Pisco, J. P., Peet, C., Dranow, D. M., Robinson, D. A., Jansen, C., Norcross, N. R., Vinayak, S., Anderson, M., Brooks, C. F., Cooper, C. A., Damerow, S., Delves, M., Dowers, K., Duffy, J., Edwards, T. E. & 57 othersHallyburton, I., Horst, B. G., Hulverson, M. A., Ferguson, L., Jiménez-Díaz, M. B., Jumani, R. S., Lorimer, D. D., Love, M. S., Maher, S., Matthews, H., McNamara, C. W., Miller, P., O'Neill, S., Ojo, K. K., Osuna-Cabello, M., Pinto, E., Post, J., Riley, J., Rottmann, M., Sanz, L. M., Scullion, P., Sharma, A., Shepherd, S. M., Shishikura, Y., Simeons, F. R. C., Stebbins, E. E., Stojanovski, L., Straschil, U., Tamaki, F. K., Tamjar, J., Torrie, L. S., Vantaux, A., Witkowski, B., Wittlin, S., Yogavel, M., Zuccotto, F., Angulo-Barturen, I., Sinden, R., Baum, J., Gamo, F-J., Mäser, P., Kyle, D. E., Winzeler, E. A., Myler, P. J., Wyatt, P. G., Floyd, D., Matthews, D., Sharma, A., Striepen, B., Huston, C. D., Gray, D. W., Fairlamb, A. H., Pisliakov, A. V., Walpole, C., Read, K. D., Van Voorhis, W. C. & Gilbert, I. H., 2 Apr 2019, In : Proceedings of the National Academy of Sciences. 116, 14, p. 7015-7020 6 p.

Research output: Contribution to journalArticle

Open Access
File
Lysine-tRNA Ligase
Cryptosporidiosis
Cryptosporidium parvum
Malaria
Plasmodium falciparum
10 Citations (Scopus)
22 Downloads (Pure)

Intracellular Transfer of Na+ in an Active State G Protein Coupled Receptor

Vickery, O., Carvalheda Dos Santos, C., Zaidi, S. A., Pisliakov, A., Katritch, V. & Zachariae, U., 2 Jan 2018, In : Structure. 26, 1, p. 171-180.e2 12 p.

Research output: Contribution to journalArticle

Open Access
File
G-Protein-Coupled Receptors
Ions
Cytosol
Binding Sites
Ion Exchange

A new perspective in class A GPCRs: The interplay between membrane voltage, cations and protons

Vickery, O., Carvalheda Dos Santos, C., Zaidi, S. A., Pisliakov, A., Katritch, V. & Zachariae, U., 2017, In : European Biophysics Journal. 46, Suppl 1, p. S379 1 p., P-1006.

Research output: Contribution to journalMeeting abstract

Early stages of Parkin activation - A computational study

Carvalheda Dos Santos, C., Bueren-Calabuig, J., Kumar, A., Walden, H. & Pisliakov, A., 2017, In : European Biophysics Journal. 46, Suppl 1, p. S155 1 p., P-154.

Research output: Contribution to journalMeeting abstract

Mitochondrial Degradation
Phosphorylation
Allosteric Regulation
Ubiquitin-Conjugating Enzymes
Mutation
3 Citations (Scopus)
19 Downloads (Pure)

Insights into proton translocation in cbb3 oxidase from MD simulations

Carvalheda, C. A. & Pisliakov, A. V., May 2017, In : Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1858, 5, p. 396-406 11 p.

Research output: Contribution to journalArticle

Open Access
File
Protons
Proton transfer
Oxygen
Water
Protonation

Thesis

Simulation studies of the structure-function relationship of two biological processes: proton pumping in cbb3 oxidase and activation of Parkin

Author: Carvalheda Dos Santos, C. A., 2018

Supervisor: Pisliakov, A. (Supervisor) & Newman, T. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy