• 13 Citations
  • 2 h-Index
20162018
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  • 24 Similar Profiles
Ubiquitin-Protein Ligases Chemical Compounds
Hydroxyproline Chemical Compounds
Epigenomics Medicine & Life Sciences
Proteolysis Medicine & Life Sciences
Proteins Chemical Compounds
Benzodiazepines Chemical Compounds
Leucine Chemical Compounds
Degradation Chemical Compounds

Research Output 2016 2018

  • 13 Citations
  • 2 h-Index
  • 2 Article
  • 1 Review article
1 Citations

3-Fluoro-4-hydroxyprolines: Synthesis, conformational analysis and stereoselective recognition by the VHL E3 ubiquitin ligase for targeted protein degradation

Testa, A., Lucas, X., Castro, G., Chan, K. H., Wright, J., Runcie, A., Gadd, M., Harrison, W. T. A., Ko, E. J., Fletcher, D. & Ciulli, A., 25 Jul 2018, In : Journal of the American Chemical Society. 140, 29, p. 9299-9313 15 p.

Research output: Contribution to journalArticle

Open Access
File
Hydroxyproline
Ubiquitin-Protein Ligases
Proteolysis
Proteins
Degradation
3 Citations

Optimization of a “Bump-and-Hole” Approach to Allele-Selective BET Bromodomain Inhibition

Runcie, A., Zengerle, M., Chan, K. H., Testa, A., Van Beurden, L., Baud, M., Epemolu, R., Ellis, L., Read, K., Coulthard, V., Brien, A. & Ciulli, A., 9 Mar 2018, In : Chemical Science. 2018, 9, p. 2387-2634 18 p., 2452.

Research output: Contribution to journalArticle

Open Access
File
Benzodiazepines
Leucine
Proteins
Cell proliferation
Valine
9 Citations

Chemical genetics approaches for selective intervention in epigenetics

Runcie, A. C., Chan, K. H., Zengerle, M. & Ciulli, A., Aug 2016, In : Current Opinion in Chemical Biology. 33, p. 186-194 9 p.

Research output: Contribution to journalReview article

Open Access
File
Epigenomics
Genetics
Genes
Modulation
Molecules