Projects per year
Personal profile
Research interests
My research group use quantitative proteomics and protein biochemistry to provide new molecular understanding into how immune cells sense and respond to their environment and regulate core cellular processes. I have a specific interest in T and B lymphocytes and their links to neurodegerenative disease.
Teaching
I teach across a range of modules covering Biological and Biomedical Sciences.
- Module manager for Level 3 Cell Signalling (BS32006)
- Module manager for Level 4 Advanced Cell Signalling (BS42013)
- Lecturer for Level 3 Immunology (BS32009)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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Rapid Research in Covid -19 Programme
Barrable, A. (Investigator), Belch, J. (Investigator), Boehnke, J. (Investigator), Booth, D. (Investigator), Brown, A. (Investigator), Cantrell, D. (Investigator), Chalmers, J. (Investigator), Coleman, S. (Investigator), Connell, D. (Investigator), Cuschieri, A. (Investigator), Dicker, A. (Investigator), Doney, A. (Investigator), Eftimie, R. (Investigator), Fang, M. (Investigator), Farre, A. (Investigator), Gamble, C. (Investigator), Howden, A. (Investigator), Krstajic, N. (Investigator), Lamond, A. (Investigator), Moraga Gonzalez, I. (Investigator), Palmer, C. (Investigator), Parcell, B. (Investigator), Pearson, E. (Investigator), Shoemark, A. (Investigator) & Sixsmith, J. (Investigator)
1/06/20 → 30/09/21
Project: Research
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Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells
Sinclair, L. V. (Lead / Corresponding author), Youdale, T., Spinelli, L., Gakovic, M., Langlands, A. J., Pathak, S., Howden, A. J. M., Ganley, I. G. & Cantrell, D. A. (Lead / Corresponding author), 27 Feb 2025, In: Nature Immunology. 26, p. 429-443 32 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Dundee Research Interest Group Open Doors Day Event Report 2025
Patrick, S., Hardie, G., Hawdon, B., Goodburn, J., Coxe, M., Milne, J., Rigg, D., Sammler, E. (Editor), Howden, A. (Editor), Alessi, D. (Contributing member), Lacey-Solymar, G. (Contributing member) & Nash, L., 28 Feb 2025, Dundee: University of Dundee. 11 p.Research output: Book/Report › Book
Open AccessFile64 Downloads (Pure) -
Synaptic signatures and disease vulnerabilities of layer 5 pyramidal neurons
Marcassa, G., Dascenco, D., Lorente-Echeverría, B., Daaboul, D., Vandensteen, J., Leysen, E., Baltussen, L., Howden, A. J. M. & de Wit, J. (Lead / Corresponding author), 2 Jan 2025, In: Nature Communications. 16, 16 p., 228.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Downloads (Pure) -
A proteomic map of B cell activation and its shaping by mTORC1, MYC and iron
James, O., Sinclair, L. V., Lefter, N., Salerno, F., Brenes, A. & Howden, A. J. M. (Lead / Corresponding author), 22 Dec 2024, BioRxiv, 40 p.Research output: Working paper/Preprint › Preprint
File5 Downloads (Pure) -
Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells
Sinclair, L. V. (Lead / Corresponding author), Youdale, T., Spinelli, L., Gakovic, M., Langlands, A. J., Pathak, S., Howden, A. J. M., Ganley, I. G. & Cantrell, D. A. (Lead / Corresponding author), 11 Jun 2024, BioRxiv, 44 p.Research output: Working paper/Preprint › Preprint
File4 Downloads (Pure)
Activities
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Dundee Research Interest Group Open Doors Day 2025
Alessi, D. (Participant), Sammler, E. (Organiser), Howden, A. (Organiser), Muqit, M. (Participant), Ganley, I. (Participant), Gilbertson, T. (Participant), Farnaby, W. (Participant), Hardie, G. (Participant), Hawdon, B. (Organiser), Goodburn, J. (Organiser), Coxe, M. (Participant), Milne, J. (Participant), Rigg, D. (Participant), Vangheluwe, P. (Participant), Kerr, J. (Participant), Stewart, T. (Participant), Lacey-Solymar, G. (Participant), Patrick, S. (Participant), Nash, L. (Participant), Langlands, A. (Participant), Hirons, Z. (Organiser), Grayson, L. (Contributor), Bishnu, A. (Participant), Wilhelm, L. (Participant), Appleton, P. (Participant), Filipe Soares, R. (Participant), Robertson, J. (Participant), Ibba, R. (Participant), Hallatt, A. (Participant) & Wieske, L. (Participant)
28 Feb 2025Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Invited speaker at the British Society of Immunology Scottish conference
Howden, A. (Speaker)
20 Mar 2024Activity: Talk or presentation types › Invited talk
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Grant Reviewer for MRC Clinical Senior Research Fellowship
Howden, A. (Member)
11 Jun 2024Activity: Other activity types › Other
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Grant Reviewer for MRC project grant
Howden, A. (Member)
18 Jul 2024Activity: Other activity types › Other
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The Michael J. Fox Foundation for Parkinson's Research, New York, NY, USA
Howden, A. (Visiting researcher)
20 Nov 2024Activity: Visiting an external institution types › Visiting an external institution - other