Personal profile
Research interests
My research group use quantitative proteomics and protein biochemistry to provide new molecular understanding into how immune cells sense and respond to their environment and regulate core cellular processes. I have a specific interest in T and B lymphocytes and their links to neurodegerenative disease.
Teaching
I teach across a range of modules covering Biological and Biomedical Sciences.
- Module manager for Level 3 Cell Signalling (BS32006)
- Module manager for Level 4 Advanced Cell Signalling (BS42013)
- Lecturer for Level 3 Immunology (BS32009)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Immune cell profiling and quality control position
Howden, A. (Investigator)
1/08/25 → 31/07/26
Project: Research
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Rapid Research in Covid -19 Programme
Barrable, A. (Investigator), Belch, J. (Investigator), Boehnke, J. (Investigator), Booth, D. (Investigator), Brown, A. (Investigator), Cantrell, D. (Investigator), Chalmers, J. (Investigator), Coleman, S. (Investigator), Connell, D. (Investigator), Cuschieri, A. (Investigator), Dicker, A. (Investigator), Doney, A. (Investigator), Eftimie, R. (Investigator), Fang, M. (Investigator), Farre, A. (Investigator), Gamble, C. (Investigator), Howden, A. (Investigator), Krstajic, N. (Investigator), Lamond, A. (Investigator), Moraga Gonzalez, I. (Investigator), Palmer, C. (Investigator), Parcell, B. (Investigator), Pearson, E. (Investigator), Shoemark, A. (Investigator) & Sixsmith, J. (Investigator)
1/06/20 → 30/09/21
Project: Research
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Author Correction: Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells (Nature Immunology, (2025), 26, 3, (429-443), 10.1038/s41590-025-02090-1)
Sinclair, L. V., Youdale, T., Spinelli, L., Gakovic, M., Langlands, A. J., Pathak, S., Howden, A. J. M., Ganley, I. G. & Cantrell, D. A., 20 Jan 2026, In: Nature Immunology. 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile5 Downloads (Pure) -
Author Correction: Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity (Nature Immunology, (2025), 26, 11, (1903-1915), 10.1038/s41590-025-02301-9)
The PHOSP-COVID Study Collaborative Group, Feb 2026, In: Nature Immunology. 27, 2, p. 377 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile -
Dundee Research Interest Group (DRIG) 2026 Open Doors Day Event Report
Patrick, S., Hawdon, B., Goodburn, J., Sammler, E., Alessi, D., Hardie, G., Rigg, D., Donaldson, K., Donaldson, M., Robertson, B., Robertson, H., Milne, J., Kiely, M., Edwards, A., McNeill , C., Coxe, M., Howden, A. (Editor), Muqit, M. (Editor), Lousa, C. (Editor) & Nash, L. (Contributing member), 27 Jan 2026, Dundee: University of Dundee. 23 p.Research output: Book/Report › Other report
Open AccessFile31 Downloads (Pure) -
Fine-tuning BACH2 dosage balances stemness and effector function to enhance antitumor T cell therapy
Conti, A. G. (Lead / Corresponding author), Evans, A. C. (Lead / Corresponding author), von Linde, T., Deguit, C. D. T., Whiteside, S. K., Wesolowski, A. J., Imianowski, C. J., Yamashita-Kanemaru, Y., Dahmani, L., Chapman, J., Pillay, A. M., Al-Deka, A., Greaves, R., Burton, O., Vardaka, P., Sampurno, S., Pérez-Núñez, I., Saw, N. Y. L., Yang, J. & Howden, A. J. M. & 5 others, , 16 Jan 2026, (E-pub ahead of print) In: Nature Immunology.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)14 Downloads (Pure) -
Ancient genomic linkage of α-globin and Nprl3 couples metabolism with erythropoiesis
Preston, A. E. (Lead / Corresponding author), Frost, J. N., Teh, M. R., Badat, M., Armitage, A. E., Norfo, R., Wideman, S. K., Hanifi, M., White, N., Roy, N. B. A., Babbs, C., Ghesquiere, B., Davies, J., Howden, A. J. M., Sinclair, L. V., Hughes, J. R., Kassouf, M., Beagrie, R., Higgs, D. R. (Lead / Corresponding author) & Drakesmith, H. (Lead / Corresponding author), 24 Mar 2025, (E-pub ahead of print) In: Nature Communications. 16, 1, 15 p., 2749.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)34 Downloads (Pure)
Datasets
Activities
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Dundee Research Interest Group Open Doors Day 2026
Alessi, D. (Speaker), Howden, A. (Organiser), Hawdon, B. (Organiser), Bandmann, O. (Speaker), Hardie, G. (Contributor), Caldwell, M. (Speaker), Rigg, D. (Contributor), Donaldson, K. (Contributor), Donaldson, M. (Contributor), Robertson, B. (Contributor), Robertson, H. (Contributor), Sammler, E. (Speaker), Cellan-Jones, R. (Speaker), Milne, J. (Contributor), Flitton, C. (Presenter), Elshani, S. (Presenter), Lis, P. (Presenter), Gomes Moreira, S. (Presenter), Farnaby, W. (Presenter), Kidd, G. (Presenter), Goodburn, J. (Organiser), Hallatt, A. (Presenter), Robertson, J. (Presenter), Urbina Teixidor, A. (Presenter), Tan, Z. Y. (Presenter), Ganley, I. (Presenter), Kiely, M. (Contributor), Muqit, M. (Presenter), de Marcos Lousa, C. (Presenter), Yang, Z. (Presenter), Zeneviciute, K. (Presenter), Langlands, A. (Presenter), Edwards, A. (Contributor), McNeill , C. (Contributor), Clarke, R. (Presenter), Lefter, N. (Presenter), Baker, C. (Presenter), Patrick, S. (Contributor), Hirons, Z. (Advisor), Nash, L. (Contributor), Macmillan, C. (Contributor), Jacobs, L. (Contributor), Munro, D. (Contributor), Nelson, H. (Contributor), Taylor, L. (Contributor), Ellmers, M. (Contributor), Matson, S. (Contributor), Sahu, M. (Presenter), Pratuseviciute, N. (Presenter), Promchai, N. (Presenter) & Fasimoye, R. (Presenter)
27 Jan 2026Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Work Experience at the School of Life Sciences 2025
Hardee, E. (Organiser), Booth, K. (Contributor), Cantrell, D. (Contributor), Crossman, A. (Contributor), Christie, G. (Contributor), Dennison, N. (Contributor), Gilmour, G. (Contributor), Rousseau, A. (Contributor), Howden, A. (Contributor), -, S. (Contributor) & Wieske, L. (Contributor)
21 Jul 2025 → 22 Jul 2025Activity: Other activity types › Schools engagement
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Dundee Research Interest Group Open Doors Day 2025
Alessi, D. (Participant), Sammler, E. (Organiser), Howden, A. (Organiser), Muqit, M. (Participant), Ganley, I. (Participant), Gilbertson, T. (Participant), Farnaby, W. (Participant), Hardie, G. (Participant), Hawdon, B. (Organiser), Goodburn, J. (Organiser), Coxe, M. (Participant), Milne, J. (Participant), Rigg, D. (Participant), Vangheluwe, P. (Participant), Kerr, J. (Participant), Stewart, T. (Participant), Lacey-Solymar, G. (Participant), Patrick, S. (Participant), Nash, L. (Participant), Langlands, A. (Participant), Hirons, Z. (Organiser), Grayson, L. (Contributor), Bishnu, A. (Participant), Wilhelm, L. (Participant), Appleton, P. (Participant), Filipe Soares, R. (Participant), Robertson, J. (Participant), Ibba, R. (Participant), Hallatt, A. (Participant) & Wieske, L. (Participant)
28 Feb 2025Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Grant Reviewer for MRC project grant
Howden, A. (Member)
18 Jul 2024Activity: Other activity types › Other
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Grant Reviewer for MRC Clinical Senior Research Fellowship
Howden, A. (Member)
11 Jun 2024Activity: Other activity types › Other