Projects per year
Personal profile
Research interests
My research group use quantitative proteomics and protein biochemistry to provide new molecular understanding into how immune cells sense and respond to their environment and regulate core cellular processes. I have a specific interest in T and B lymphocytes and their links to neurodegerenative disease.
Teaching
I teach across a range of modules covering Biological and Biomedical Sciences.
- Module manager for Level 3 Cell Signalling (BS32006)
- Module manager for Level 4 Advanced Cell Signalling (BS42013)
- Lecturer for Level 3 Immunology (BS32009)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Immune cell profiling and quality control position
Howden, A. (Investigator)
1/08/25 → 31/07/26
Project: Research
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Rapid Research in Covid -19 Programme
Barrable, A. (Investigator), Belch, J. (Investigator), Boehnke, J. (Investigator), Booth, D. (Investigator), Brown, A. (Investigator), Cantrell, D. (Investigator), Chalmers, J. (Investigator), Coleman, S. (Investigator), Connell, D. (Investigator), Cuschieri, A. (Investigator), Dicker, A. (Investigator), Doney, A. (Investigator), Eftimie, R. (Investigator), Fang, M. (Investigator), Farre, A. (Investigator), Gamble, C. (Investigator), Howden, A. (Investigator), Krstajic, N. (Investigator), Lamond, A. (Investigator), Moraga Gonzalez, I. (Investigator), Palmer, C. (Investigator), Parcell, B. (Investigator), Pearson, E. (Investigator), Shoemark, A. (Investigator) & Sixsmith, J. (Investigator)
1/06/20 → 30/09/21
Project: Research
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Ancient genomic linkage of α-globin and Nprl3 couples metabolism with erythropoiesis
Preston, A. E. (Lead / Corresponding author), Frost, J. N., Teh, M. R., Badat, M., Armitage, A. E., Norfo, R., Wideman, S. K., Hanifi, M., White, N., Roy, N. B. A., Babbs, C., Ghesquiere, B., Davies, J., Howden, A. J. M., Sinclair, L. V., Hughes, J. R., Kassouf, M., Beagrie, R., Higgs, D. R. (Lead / Corresponding author) & Drakesmith, H. (Lead / Corresponding author), 24 Mar 2025, (E-pub ahead of print) In: Nature Communications. 16, 1, 15 p., 2749.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Downloads (Pure) -
Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells
Sinclair, L. V. (Lead / Corresponding author), Youdale, T., Spinelli, L., Gakovic, M., Langlands, A. J., Pathak, S., Howden, A. J. M., Ganley, I. G. & Cantrell, D. A. (Lead / Corresponding author), 27 Feb 2025, In: Nature Immunology. 26, p. 429-443 32 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)39 Downloads (Pure) -
Dundee Research Interest Group Open Doors Day Event Report 2025
Patrick, S., Hardie, G., Hawdon, B., Goodburn, J., Coxe, M., Milne, J., Rigg, D., Sammler, E. (Editor), Howden, A. (Editor), Alessi, D. (Contributing member), Lacey-Solymar, G. (Contributing member) & Nash, L., 28 Feb 2025, Dundee: University of Dundee. 11 p.Research output: Book/Report › Book
Open AccessFile150 Downloads (Pure) -
Inflammation and IL-4 regulate Parkinson’s and Crohn’s disease associated kinase LRRK2
Dikovskaya, D. (Lead / Corresponding author), Pemberton, R., Taylor, M., Tasegian, A., Bhattacharya, P., Zeneviciute, K., Sammler, E. M., Howden, A. J. M., Alessi, D. R. & Swamy, M. (Lead / Corresponding author), 8 Jul 2025, In: EMBO Reports. 26, 13, p. 3327-3356 30 p., NS20180005.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)22 Downloads (Pure) -
Lipopolysaccharide stimulates dynamic changes in B cell metabolism to promote proliferation
Cheung, D. M. S., Razsolkov, M., Bonacina, F., Andrews, S., Sumoreeah, M., Sinclair, L. V., Howden, A. J. M. & Arthur, J. S. C. (Lead / Corresponding author), 25 Aug 2025, BioRxiv, 40 p.Research output: Working paper/Preprint › Preprint
File34 Downloads (Pure)
Datasets
Activities
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Dundee Research Interest Group Open Doors Day 2025
Alessi, D. (Participant), Sammler, E. (Organiser), Howden, A. (Organiser), Muqit, M. (Participant), Ganley, I. (Participant), Gilbertson, T. (Participant), Farnaby, W. (Participant), Hardie, G. (Participant), Hawdon, B. (Organiser), Goodburn, J. (Organiser), Coxe, M. (Participant), Milne, J. (Participant), Rigg, D. (Participant), Vangheluwe, P. (Participant), Kerr, J. (Participant), Stewart, T. (Participant), Lacey-Solymar, G. (Participant), Patrick, S. (Participant), Nash, L. (Participant), Langlands, A. (Participant), Hirons, Z. (Organiser), Grayson, L. (Contributor), Bishnu, A. (Participant), Wilhelm, L. (Participant), Appleton, P. (Participant), Filipe Soares, R. (Participant), Robertson, J. (Participant), Ibba, R. (Participant), Hallatt, A. (Participant) & Wieske, L. (Participant)
28 Feb 2025Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Work Experience at the School of Life Sciences 2025
Hardee, E. (Organiser), Booth, K. (Contributor), Cantrell, D. (Contributor), Crossman, A. (Contributor), Christie, G. (Contributor), Dennison, N. (Contributor), Gilmour, G. (Contributor), Rousseau, A. (Contributor), Howden, A. (Contributor), -, S. (Contributor) & Wieske, L. (Contributor)
21 Jul 2025 → 22 Jul 2025Activity: Other activity types › Schools engagement
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Grant Reviewer for MRC project grant
Howden, A. (Member)
18 Jul 2024Activity: Other activity types › Other
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Grant Reviewer for MRC Clinical Senior Research Fellowship
Howden, A. (Member)
11 Jun 2024Activity: Other activity types › Other
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Invited seminar speaker at the Centre for Inflammation Research, University of Edinburgh
Howden, A. (Speaker)
3 Dec 2024Activity: Talk or presentation types › Invited talk