Hope, Anthony

Dr

  • United Kingdom

  • 672 Citations
  • 12 h-Index
1993 …2019
If you made any changes in Pure these will be visible here soon.

Fingerprint Dive into the research topics where Anthony Hope is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 12 Similar Profiles
Receptors, Serotonin, 5-HT3 Medicine & Life Sciences
Granisetron Medicine & Life Sciences
Serotonin Medicine & Life Sciences
Serotonin Receptors Medicine & Life Sciences
Pharmacology Medicine & Life Sciences
Tubocurarine Medicine & Life Sciences
Acyl Carrier Protein Medicine & Life Sciences
Oocytes Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1993 2019

  • 672 Citations
  • 12 h-Index
  • 15 Article

Novel pharmacological actions of Trequinsin Hydrochloride improve human sperm cell motility and function

McBrinn, R. C., Fraser, J., Hope, A. G., Gray, D. W., Barratt, C. L. R., Martins da Silva, S. J. & Brown, S. G., 1 Aug 2019, In : British Journal of Pharmacology.

Research output: Contribution to journalArticle

Sperm Motility
Cell Movement
Pharmacology
Spermatozoa
Electrophysiology
3 Citations (Scopus)
94 Downloads (Pure)

Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem

Martins Da Silva, S. J., Brown, S. G., Sutton, K., King, L. V., Ruso, H., Gray, D. W., Wyatt, P. G., Kelly, M. C., Barratt, C. L. R. & Hope, A. G., May 2017, In : Human Reproduction. 32, 5, p. 974-984 11 p.

Research output: Contribution to journalArticle

Open Access
File
Male Infertility
Drug Discovery
Spermatozoa
Sperm-Ovum Interactions
Sperm Motility
16 Citations (Scopus)
173 Downloads (Pure)

Identifying Inhibitors of Inflammation: A Novel High-Throughput MALDI-TOF Screening Assay for Salt-Inducible Kinases (SIKs)

Heap, R. E., Hope, A. G., Pearson, L-A., Reyskens, K. M. S. E., McElroy, S. P., Hastie, C. J., Porter, D. W., Arthur, J. S. C., Gray, D. W. & Trost, M., 1 Dec 2017, In : SLAS Discovery. 22, 10, p. 1193-1202 10 p.

Research output: Contribution to journalArticle

Open Access
File
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Assays
Screening
Phosphotransferases
Salts
96 Downloads (Pure)

A substrate mimic allows high-throughput assay of the FabA protein and consequently the identification of a novel inhibitor of Pseudomonas aeruginosa FabA

Moynié, L., Hope, A. G., Finzel, K., Schmidberger, J., Leckie, S. M., Schneider, G., Burkart, M. D., Smith, A. D., Gray, D. W. & Naismith, J. H., 16 Jan 2016, In : Journal of Molecular Biology. 428, 1, p. 108-120 13 p.

Research output: Contribution to journalArticle

Open Access
File
Pseudomonas aeruginosa
Acyl Carrier Protein
Enzyme Assays
Dehydration
Proteins
80 Citations (Scopus)
74 Downloads (Pure)

Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation

Kazlauskaite, A., Martínez-Torres, R. J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., Johnson, C., Zhang, J., Hope, A. G., Peggie, M., Trost, M., van Aalten, D. M., Alessi, D. R., Prescott, A. R., Knebel, A., Walden, H. & Muqit, M. MK., 1 Aug 2015, In : EMBO Reports. 16, 8, p. 939-954 16 p.

Research output: Contribution to journalArticle

Open Access
File
Phosphorylation
Ubiquitin
Serine
Chemical activation
Ubiquitin-Protein Ligases