Hope, Anthony


  • United Kingdom

  • 687 Citations
  • 12 h-Index
1993 …2019
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Fingerprint Dive into the research topics where Anthony Hope is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 11 Similar Profiles
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Research Output 1993 2019

  • 687 Citations
  • 12 h-Index
  • 15 Article
8 Downloads (Pure)

Novel pharmacological actions of Trequinsin Hydrochloride improve human sperm cell motility and function

McBrinn, R. C., Fraser, J., Hope, A. G., Gray, D. W., Barratt, C. L. R., Martins da Silva, S. J. & Brown, S. G., Dec 2019, In : British Journal of Pharmacology. 176, 23, p. 4521-4536 16 p.

Research output: Contribution to journalArticle

Open Access
Sperm Motility
Cell Movement
6 Citations (Scopus)
122 Downloads (Pure)

Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem

Martins Da Silva, S. J., Brown, S. G., Sutton, K., King, L. V., Ruso, H., Gray, D. W., Wyatt, P. G., Kelly, M. C., Barratt, C. L. R. & Hope, A. G., May 2017, In : Human Reproduction. 32, 5, p. 974-984 11 p.

Research output: Contribution to journalArticle

Open Access
Male Infertility
Drug Discovery
Sperm-Ovum Interactions
Sperm Motility
19 Citations (Scopus)
215 Downloads (Pure)

Identifying Inhibitors of Inflammation: A Novel High-Throughput MALDI-TOF Screening Assay for Salt-Inducible Kinases (SIKs)

Heap, R. E., Hope, A. G., Pearson, L-A., Reyskens, K. M. S. E., McElroy, S. P., Hastie, C. J., Porter, D. W., Arthur, J. S. C., Gray, D. W. & Trost, M., 1 Dec 2017, In : SLAS Discovery. 22, 10, p. 1193-1202 10 p.

Research output: Contribution to journalArticle

Open Access
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
124 Downloads (Pure)

A substrate mimic allows high-throughput assay of the FabA protein and consequently the identification of a novel inhibitor of Pseudomonas aeruginosa FabA

Moynié, L., Hope, A. G., Finzel, K., Schmidberger, J., Leckie, S. M., Schneider, G., Burkart, M. D., Smith, A. D., Gray, D. W. & Naismith, J. H., 16 Jan 2016, In : Journal of Molecular Biology. 428, 1, p. 108-120 13 p.

Research output: Contribution to journalArticle

Open Access
Pseudomonas aeruginosa
Acyl Carrier Protein
Enzyme Assays
83 Citations (Scopus)
103 Downloads (Pure)

Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation

Kazlauskaite, A., Martínez-Torres, R. J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., Johnson, C., Zhang, J., Hope, A. G., Peggie, M., Trost, M., van Aalten, D. M., Alessi, D. R., Prescott, A. R., Knebel, A., Walden, H. & Muqit, M. MK., 1 Aug 2015, In : EMBO Reports. 16, 8, p. 939-954 16 p.

Research output: Contribution to journalArticle

Open Access
Chemical activation
Ubiquitin-Protein Ligases