Crossman, Arthur

Lecturer (Teaching and Scholarship), DArcy Thompson Unit

657 Citations
15 h-Index

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N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase Medicine & Life Sciences

Trypanosoma brucei brucei Medicine & Life Sciences

African Trypanosomiasis Medicine & Life Sciences

Biosynthesis Chemical Compounds

Glycosylphosphatidylinositols Medicine & Life Sciences

Hydroxamic Acids Chemical Compounds

Salicylic acid Chemical Compounds

Salicylic Acid Medicine & Life Sciences

Research Output 1997 2014

657 Citations
15 h-Index
25 Article
2 Meeting abstract

2 Citations (Scopus)

97 Downloads (Pure)

Fragment screening reveals salicylic hydroxamic acid as an inhibitor of Trypanosoma brucei GPI GlcNAc-PI de-N-acetylase

Urbaniak, M. D., Capes, A. S., Crossman, A., O'Neill, S., Thompson, S., Gilbert, I. H. & Ferguson, M. A. J., 31 Mar 2014, In : Carbohydrate Research. 387, p. 54-58 5 p.

Research output: Contribution to journal › Article

Open Access

File

N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase

Hydroxamic Acids

Salicylic acid

Trypanosoma brucei brucei

Salicylic Acid

4 Citations (Scopus)

107 Downloads (Pure)

Probing the substrate specificity of Trypanosoma brucei GlcNAc-PI de-N-acetylase with synthetic substrate analogues

Capes, A. S., Crossman, A., Urbaniak, M. D., Gilbert, S. H., Ferguson, M. A. J. & Gilbert, I. H., Mar 2014, In : Organic and Biomolecular Chemistry. 12, 12, p. 1919-1934 16 p.

Research output: Contribution to journal › Article

Open Access

File

N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase

Trypanosoma brucei brucei

Inositol

Substrate Specificity

inhibitors

5 Citations (Scopus)

Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness

Abdelwahab, N. Z., Crossman, A. T., Sullivan, L., Ferguson, M. A. J. & Urbaniak, M. D., Mar 2012, In : Chemical Biology & Drug Design. 79, 3, p. 270-278 9 p.

Research output: Contribution to journal › Article

7 Citations (Scopus)

13 Downloads (Pure)

Investigation of copper(II) tetrafluoroborate catalysed epoxide opening

Capes, A. S., Crossman, A. T., Webster, L. A., Ferguson, M. A. J. & Gilbert, I. H., 28 Dec 2011, In : Tetrahedron Letters. 52, 52, p. 7091-7094 4 p.

Research output: Contribution to journal › Article

Epoxy Compounds

Copper

Alcohols

4 Citations (Scopus)

Synthesis of potential metal-binding group compounds to examine the zinc dependency of the GPI de-N-acetylase metalloenzyme in Trypanosoma brucei

Abdelwahab, N. Z., Urbaniak, M. D., Ferguson, M. A. J. & Crossman, A. T., 1 May 2011, In : Carbohydrate Research. 346, 6, p. 708-714 7 p.

Research output: Contribution to journal › Article