Knebel, Axel

Dr

  • Senior investigator Scientist (MRC), MRC PPU
  • United Kingdom

  • 2746 Citations
  • 25 h-Index
20012019
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Fingerprint Dive into the research topics where Axel Knebel is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Ubiquitin Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Phosphorylation Chemical Compounds
Cullin Proteins Medicine & Life Sciences
Polyubiquitin Medicine & Life Sciences
Proteins Chemical Compounds
Ligases Medicine & Life Sciences
Ubiquitination Medicine & Life Sciences

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Research Output 2001 2019

  • 2746 Citations
  • 25 h-Index
  • 44 Article
2 Citations (Scopus)
75 Downloads (Pure)

Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling

Kelsall, I. R., Kristariyanto, Y. A., Knebel, A., Wood, N. T., Kulathu, Y. & Alpi, A. F., 22 Feb 2019, In : Journal of Biological Chemistry. 294, 8, p. 2651-2664 14 p.

Research output: Contribution to journalArticle

Open Access
File
Cullin Proteins
Ubiquitin-Protein Ligases
Ligases
Ubiquitin
Ubiquitins
4 Citations (Scopus)
121 Downloads (Pure)

Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus

Odqvist, L., Jevnikar, Z., Riise, R., Öberg, L., Rhedin, M., Leonard, D., Yrlid, L., Jackson, S., Mattsson, J., Nanda, S., Cohen, P., Knebel, A., Arthur, S., Thörn, K., Svenungsson, E., Jönsen, A., Gunnarsson, I., Tandre, K., Alexsson, A., Kastbom, A. & 10 others, Rantapää-Dahlqvist, S., Eloranta, M-L., Syvänen, A-C., Bengtsson, A., Johansson, P., Sandling, J. K., Sjöwall, C., Rönnblom, L., Collins, B. & Vaarala, O., 12 Jul 2019, In : Annals of the Rheumatic Diseases. 8 p.

Research output: Contribution to journalArticle

Open Access
File
Systemic Lupus Erythematosus
Polymorphism
Clustered Regularly Interspaced Short Palindromic Repeats
Genes
RNA Sequence Analysis
12 Downloads (Pure)

PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins

Berndsen, K., Lis, P., Yeshaw, W. M., Wawro, P. S., Nirujogi, R., Wightman, M., Macartney, T., Dorward, M., Knebel, A., Tonelli, F., Pfeffer, S. R. & Alessi, D., 12 Nov 2019, In : eLife. 8, p. 1-37 37 p., e50416.

Research output: Contribution to journalArticle

Open Access
File
Phosphoric Monoester Hydrolases
Phosphorylation
Phosphoprotein Phosphatases
Parkinson Disease
rab GTP-Binding Proteins
1 Citation (Scopus)
50 Downloads (Pure)
Open Access
File
Ubiquitin-Protein Ligases
Ubiquitin
Esters
Ubiquitin C
Macrophages
25 Citations (Scopus)
180 Downloads (Pure)

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity

Pao, K-C., Wood, N. T., Knebel, A., Rafie, K., Stanley, M., Mabbitt, P. D., Sundaramoorthy, R., Hofmann, K., van Aalten, D. M. F. & Virdee, S., 11 Apr 2018, In : Nature. 556, 7701, p. 381-385 5 p.

Research output: Contribution to journalArticle

Open Access
File
Ubiquitin-Protein Ligases
Esterification
Ubiquitin
Genes
Ubiquitination