Research output per year
Research output per year
- 1 - 50 out of 54 results
Search results
-
2024
Design and high-throughput implementation of MALDI-TOF/MS-based assays for Parkin E3 ligase activity
Traynor, R., Moran, J., Stevens, M., Antico, O., Knebel, A., Behrouz, B., Merchant, K., Hastie, C. J., Davies, P., Muqit, M. M. K. & De Cesare, V. (Lead / Corresponding author), 26 Feb 2024, In: Cell Reports Methods. 4, 2, 16 p., 100712.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)78 Downloads (Pure) -
Discovery and characterization of noncanonical E2-conjugating enzymes
Abdul Rehman, S. A., Cazzaniga, C., Di Nisio, E., Antico, O., Knebel, A., Johnson, C., Şahin, A. T., Ibrahim, P. E. G. F., Lamoliatte, F., Negri, R., Miratul Muqit, M. K. & De Cesare, V. (Lead / Corresponding author), 29 Mar 2024, In: Science Advances. 10, 13, 18 p., adh0123.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)70 Downloads (Pure) -
VCP/p97-associated proteins are binders and debranching enzymes of K48–K63-branched ubiquitin chains
Lange, S. M. (Lead / Corresponding author), McFarland, M. R., Lamoliatte, F., Carroll, T., Krshnan, L., Pérez-Ràfols, A., Kwaśna, D., Shen, L., Wallace, I., Cole, I., Armstrong, L. A., Knebel, A., Johnson, C., De Cesare, V. & Kulathu, Y. (Lead / Corresponding author), 8 Jul 2024, (E-pub ahead of print) In: Nature Structural & Molecular Biology. 35 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)109 Downloads (Pure) -
2022
HOIL-1 ubiquitin ligase activity targets unbranched glucosaccharides and is required to prevent polyglucosan accumulation
Kelsall, I. R. (Lead / Corresponding author), McCrory, E. H., Xu, Y., Scudamore, C. L., Nanda, S. K., Mancebo-Gamella, P., Wood, N. T., Knebel, A., Matthews, S. J. & Cohen, P. (Lead / Corresponding author), 19 Apr 2022, In: EMBO Journal. 41, 8, p. 1-17 17 p., e109700.Research output: Contribution to journal › Article › peer-review
Open AccessFile50 Citations (Scopus)262 Downloads (Pure) -
Human UFSP1 is an active protease that regulates UFM1 maturation and UFMylation
Millrine, D., Cummings, T., Matthews, S. P., Peter, J. J., Magnussen, H. M., Lange, S. M., Macartney, T., Lamoliatte, F., Knebel, A. & Kulathu, Y. (Lead / Corresponding author), 9 Aug 2022, In: Cell Reports. 40, 5, 21 p., 111168.Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Citations (Scopus)334 Downloads (Pure) -
2021
Mechanism of activation and regulation of Deubiquitinase activity in MINDY1 and MINDY2
Rehman, S. A. A., Armstrong, L. A., Lange, S. M., Kristariyanto, Y. A., Gräwert, T. W., Knebel, A., Svergun, D. I. & Kulathu, Y. (Lead / Corresponding author), 21 Oct 2021, In: Molecular Cell. 81, 20, p. 4176-4190.e6 21 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)210 Downloads (Pure) -
Structural basis for the specificity of PPM1H phosphatase for Rab GTPases
Waschbüsch, D., Berndsen, K., Lis, P., Knebel, A., Lam, Y. P. Y., Alessi, D. R. (Lead / Corresponding author) & Khan, A. R. (Lead / Corresponding author), 4 Nov 2021, In: EMBO Reports. 22, 11, 22 p., e52675.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)254 Downloads (Pure) -
2020
A complex comprising C15ORF41 and Codanin-1- the products of two genes mutated in congenital dyserythropoietic anaemia type I (CDA-I)
Shroff, M., Knebel, A., Toth, R. & Rouse, J. (Lead / Corresponding author), 29 May 2020, In: Biochemical Journal. 477, 10, p. 1893-1905 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)103 Downloads (Pure) -
High-throughput matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry–based deubiquitylating enzyme assay for drug discovery
De Cesare, V. (Lead / Corresponding author), Moran, J., Traynor, R., Knebel, A., Ritorto, M. S., Trost, M., McLauchlan, H., Hastie, C. J. & Davies, P. (Lead / Corresponding author), Dec 2020, In: Nature Protocols. 15, 12, p. 4034-4057 26 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Citations (Scopus) -
Human ANKLE1 is a nuclease specific for branched DNA
Song, J., Freeman, A. D. J., Knebel, A., Gartner, A. & Lilley, D. M. J. (Lead / Corresponding author), 2 Oct 2020, In: Journal of Molecular Biology. 432, 21, p. 5825-5834 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)122 Downloads (Pure) -
2019
Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling
Kelsall, I. R., Kristariyanto, Y. A., Knebel, A., Wood, N. T., Kulathu, Y. & Alpi, A. F. (Lead / Corresponding author), 22 Feb 2019, In: Journal of Biological Chemistry. 294, 8, p. 2651-2664 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)192 Downloads (Pure) -
Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus
Odqvist, L., Jevnikar, Z., Riise, R., Öberg, L., Rhedin, M., Leonard, D., Yrlid, L., Jackson, S., Mattsson, J., Nanda, S., Cohen, P., Knebel, A., Arthur, S., Thörn, K., Svenungsson, E., Jönsen, A., Gunnarsson, I., Tandre, K., Alexsson, A. & Kastbom, A. & 10 others, , 1 Oct 2019, In: Annals of the Rheumatic Diseases. 78, 10, p. 1363-1370 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile62 Citations (Scopus)366 Downloads (Pure) -
PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins
Berndsen, K., Lis, P., Yeshaw, W. M., Wawro, P. S., Nirujogi, R., Wightman, M., Macartney, T., Dorward, M., Knebel, A., Tonelli, F., Pfeffer, S. R. & Alessi, D. (Lead / Corresponding author), 12 Nov 2019, In: eLife. 8, 37 p., e50416.Research output: Contribution to journal › Article › peer-review
Open AccessFile79 Citations (Scopus)199 Downloads (Pure) -
The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells
Kelsall, I., Zhang, R., Knebel, A., Arthur, S. & Cohen, P. (Lead / Corresponding author), 2 Jul 2019, In: Proceedings of the National Academy of Sciences. 116, 27, p. 13293-13298 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile102 Citations (Scopus)233 Downloads (Pure) -
2018
Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity
Pao, K.-C., Wood, N. T., Knebel, A., Rafie, K., Stanley, M., Mabbitt, P. D., Sundaramoorthy, R., Hofmann, K., van Aalten, D. M. F. & Virdee, S. (Lead / Corresponding author), 11 Apr 2018, In: Nature. 556, 7701, p. 381-385 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile201 Citations (Scopus)1214 Downloads (Pure) -
Phosphorylation of Parkin at Serine65 is essential for its activation in vivo
McWilliams, T. G. (Lead / Corresponding author), Barini, E., Pohjolan-Pirhonen, R., Brooks, S. P., Singh, F., Burel, S., Balk, K., Kumar, A., Montava Garriga, L., Prescott, A., Hassoun, S. M., Mouton-Liger, F., Ball, G., Hills, R., Knebel, A., Ulusoy, A., Di Monte, D. A., Tamjar, J., Antico, O. & Fears, K. & 11 others, , Nov 2018, In: Open Biology. 8, 11, 18 p., 181108.Research output: Contribution to journal › Article › peer-review
Open AccessFile85 Citations (Scopus)317 Downloads (Pure) -
RNF12 X-linked intellectual disability mutations disrupt E3 ligase activity and neural differentiation
Bustos, F., Segarra Fas, A., Chaugule, V. K., Brandenburg, L., Branigan, E., Toth, R., Macartney, T., Knebel, A., Hay, R., Walden, H. & Findlay, G. (Lead / Corresponding author), 8 May 2018, In: Cell Reports. 23, 6, p. 1599-1611 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Citations (Scopus)484 Downloads (Pure) -
The MALDI TOF E2/E3 ligase assay as universal tool for drug discovery in the ubiquitin pathway
De Cesare, V. (Lead / Corresponding author), Johnson, C., Barlow, V., Hastie, C., Knebel, A. & Trost, M. (Lead / Corresponding author), 20 Sept 2018, In: Cell Chemical Biology. 25, 9, p. 1117-1127.4 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile54 Citations (Scopus)268 Downloads (Pure) -
2017
A single MIU motif of MINDY-1 recognizes K48-linked polyubiquitin chains
Kristariyanto, Y., Rehman, S. A. A., Weidlich, S., Knebel, A. & Kulathu, Y. (Lead / Corresponding author), 1 Mar 2017, In: EMBO Reports. 18, 3, p. 392-402 11 p., e201643205.Research output: Contribution to journal › Article › peer-review
Open AccessFile49 Citations (Scopus)257 Downloads (Pure) -
CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis
Sonneville, R., Priego Moreno, S., Knebel, A., Johnson, C., Hastie, C. J., Gartner, A., Gambus, A. (Lead / Corresponding author) & Labib, K. (Lead / Corresponding author), 3 Apr 2017, In: Nature Cell Biology. 19, p. 468-479 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile77 Citations (Scopus)272 Downloads (Pure) -
Parkin–phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity
Kumar, A., Chaugule, V. K., Condos, T. E. C., Barber, K. R., Johnson, C., Toth, R., Sundaramoorthy, R., Knebel, A., Shaw, G. S. & Walden, H. (Lead / Corresponding author), May 2017, In: Nature Structural & Molecular Biology. 24, 5, p. 475-483 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile72 Citations (Scopus)470 Downloads (Pure) -
Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3)
Logie, L., Van Aalten, L., Knebel, A., Force, T., Hastie, C. J., MacLauchlan, H., Campbell, D. G., Gourlay, R., Prescott, A., Davidson, J., Fuller, W. & Sutherland, C. (Lead / Corresponding author), 15 Dec 2017, In: Scientific Reports. 7, p. 1-14 14 p., 17682.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)274 Downloads (Pure) -
Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling
Strickson, S., Emmerich, C. H., Goh, E. T. H., Zhang, J., Kelsall, I. R., Macartney, T., Hastie, C. J., Knebel, A., Peggie, M., Marchesi, F., Arthur, J. S. C. & Cohen, P. (Lead / Corresponding author), 25 Apr 2017, In: Proceedings of the National Academy of Sciences. 114, 7, p. E3481-E3489 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile92 Citations (Scopus)259 Downloads (Pure) -
2016
Characterization of the mammalian family of DCN-type NEDD8 E3 ligases
Keuss, M. J., Thomas, Y., Mcarthur, R., Wood, N. T., Knebel, A. & Kurz, T. (Lead / Corresponding author), 1 Apr 2016, In: Journal of Cell Science. 129, 7, p. 1441-1454 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Citations (Scopus)269 Downloads (Pure) -
Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation
McGuire, V. A., Ruiz-Zorrilla Diez, T., Emmerich, C. H., Strickson, S., Ritorto, M. S., Sutavani, R. V., Weiβ, A., Houslay, K. F., Knebel, A., Meakin, P. J., Phair, I. R., Ashford, M. L. J., Trost, M. & Arthur, J. S. C. (Lead / Corresponding author), 8 Aug 2016, In: Scientific Reports. 6, p. 1-17 17 p., 31159.Research output: Contribution to journal › Article › peer-review
Open AccessFile88 Citations (Scopus)467 Downloads (Pure) -
Synthesis of isomeric phosphoubiquitin chains reveals that phosphorylation controls deubiquitinase activity and specificity
Huguenin-Dezot, N., De Cesare, V., Peltier, J., Knebel, A., Kristariyanto, Y. A., Rogerson, D. T., Kulathu, Y., Trost, M. (Lead / Corresponding author) & Chin, J. W. (Lead / Corresponding author), 26 Jul 2016, In: Cell Reports. 16, 4, p. 1180-1193 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile64 Citations (Scopus)216 Downloads (Pure) -
UBQLN2 mediates autophagy-independent protein aggregate clearance by the proteasome
Hjerpe, R., Bett, J. (Lead / Corresponding author), Keuss, M., Solovyova, A., McWilliams, T., Johnson, C., Sahu, I., Varghese, J., Wood, N., Wightman, M., Osborne, G., P. Bates, G., Glickman, M. H., Trost, M., Knebel, A., Marchesi, F. & Kurz, T. (Lead / Corresponding author), 11 Aug 2016, In: Cell. 166, 4, p. 935-949 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile230 Citations (Scopus)364 Downloads (Pure) -
2015
Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation
Kazlauskaite, A., Martínez-Torres, R. J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., Johnson, C., Zhang, J., Hope, A. G., Peggie, M., Trost, M., van Aalten, D. M., Alessi, D. R., Prescott, A. R., Knebel, A., Walden, H. & Muqit, M. M. (Lead / Corresponding author), 1 Aug 2015, In: EMBO Reports. 16, 8, p. 939-954 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile190 Citations (Scopus)283 Downloads (Pure) -
Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2):ElonginBC:Cullin5:RING-box protein 2 (Rbx2)
Bulatov, E., Martin, E. M., Chatterjee, S., Knebel, A., Shimamura, S., Konijnenberg, A., Johnson, C., Zinn, N., Grandi, P., Sobott, F. & Ciulli, A. (Lead / Corresponding author), 13 Feb 2015, In: Journal of Biological Chemistry. 290, 7, p. 4178-4191 14 p.Research output: Contribution to journal › Article
Open Access26 Citations (Scopus) -
Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia
Schumacher, F.-R., Siew, K., Zhang, J., Johnson, C., Wood, N., Cleary, S. E., Al Maskari, R. S., Ferryman, J. T., Hardege, I., Yasmin, [. V., Figg, N. L., Enchev, R., Knebel, A., O'Shaughnessy, K. M. & Kurz, T., 1 Oct 2015, In: EMBO Molecular Medicine. 7, 10, p. 1285-1306 22 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile86 Citations (Scopus)319 Downloads (Pure) -
Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis
Kumar, A., Aguirre, J. D., Condos, T. E. C., Martinez-Torres, R. J., Chaugule, V. K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D. E., Barber, K. R., Shaw, G. S. (Lead / Corresponding author) & Walden, H. (Lead / Corresponding author), 14 Oct 2015, In: EMBO Journal. 34, 20, p. 2506-2521 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile156 Citations (Scopus)413 Downloads (Pure) -
Orthogonal thiol functionalization at a single atomic center for profiling transthiolation activity of E1 activating enzymes
Stanley, M., Han, C., Knebel, A., Murphy, P., Shpiro, N. & Virdee, S. (Lead / Corresponding author), 19 Jun 2015, In: ACS Chemical Biology. 10, 6, p. 1542-1554 13 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Citations (Scopus) -
Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization
Madrzak, J., Fiedler, M., Johnson, C. M., Ewan, R., Knebel, A., Bienz, M. (Lead / Corresponding author) & Chin, J. W. (Lead / Corresponding author), 24 Apr 2015, In: Nature Communications. 6, 11 p., 6718.Research output: Contribution to journal › Article › peer-review
Open Access55 Citations (Scopus) -
Ubiquitin-C-terminal hydrolases cleave isopeptide and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers
Bett, J. S., Ritorto, M. S., Ewan, R., Jaffray, E. G., Virdee, S., Chin, J. W., Knebel, A., Kurz, T., Trost, M., Tatham, M. H. & Hay, R. T. (Lead / Corresponding author), 15 Mar 2015, In: Biochemical Journal. 466, 3, p. 489-498 10 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Citations (Scopus) -
2014
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Serine65
Kazlauskaite, A. (Lead / Corresponding author), Kondapalli, C., Gourlay, R., Campbell, D. G., Ritorto, M. S., Hofmann, K., Alessi, D. R., Knebel, A., Trost, M. & Muqit, M. M. K. (Lead / Corresponding author), 15 May 2014, In: Biochemical Journal. 460, 1, p. 127-139 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile649 Citations (Scopus)227 Downloads (Pure) -
Screening of DUB activity and specificity by MALDI-TOF mass spectrometry
Ritorto, M. S., Ewan, R., Perez-Oliva, A. B., Knebel, A., Buhrlage, S. J., Wightman, M., Kelly, S. M., Wood, N. T., Virdee, S., Gray, N. S., Morrice, N. A., Alessi, D. R. & Trost, M. (Lead / Corresponding author), 27 Aug 2014, In: Nature Communications. 5, 11 p., 4763.Research output: Contribution to journal › Article › peer-review
Open AccessFile265 Citations (Scopus)410 Downloads (Pure) -
2013
CSN-and CAND1-dependent remodelling of the budding yeast SCF complex
Zemla, A., Thomas, Y., Kedziora, S., Knebel, A., Wood, N. T., Rabut, G. & Kurz, T. (Lead / Corresponding author), 27 Mar 2013, In: Nature Communications. 4, 1641.Research output: Contribution to journal › Article › peer-review
93 Citations (Scopus) -
The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system
Strickson, S., Campbell, D. G., Emmerich, C. H., Knebel, A., Plater, L., Ritorto, M. S., Shpiro, N. & Cohen, P., 1 May 2013, In: Biochemical Journal. 451, 3, p. 427-437 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile173 Citations (Scopus)229 Downloads (Pure) -
The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction
Ohta, A., Schumacher, F.-R., Mehellou, Y., Johnson, C., Knebel, A., Macartney, T. J., Wood, N. T., Alessi, D. R. (Lead / Corresponding author) & Kurz, T. (Lead / Corresponding author), 1 Apr 2013, In: Biochemical Journal. 451, 1, p. 111-122 12 p.Research output: Contribution to journal › Article › peer-review
183 Citations (Scopus) -
TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes
Kelsall, I. R., Duda, D. M., Olszewski, J. L., Hofmann, K., Knebel, A., Langevin, F., Wood, N., Wightman, M., Schulman, B. A. & Alpi, A. F. (Lead / Corresponding author), 2013, In: EMBO Journal. 32, p. 2848-2860 13 p.Research output: Contribution to journal › Article › peer-review
86 Citations (Scopus) -
2012
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
Kondapalli, C., Kazlauskaite, A., Zhang, N., Woodroof, H. I., Campbell, D. G., Gourlay, R., Burchell, L., Walden, H., MacArtney, T. J., Deak, M., Knebel, A., Alessi, D. R. & Muqit, M. M. K. (Lead / Corresponding author), 2012, In: Open Biology. 2, 120080.Research output: Contribution to journal › Article › peer-review
741 Citations (Scopus) -
The Dac-tag, an affinity tag based on penicillin-binding protein 5
Lee, D. W., Peggie, M., Deak, M., Toth, R., Gage, Z. O., Wood, N., Schilde, C., Kurz, T. & Knebel, A., 2012, In: Analytical Biochemistry. 428, 1, p. 64-72 9 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1 alpha accumulation
Bandau, S., Knebel, A., Gage, Z. O., Wood, N. T. & Alexandru, G., 26 Apr 2012, In: BMC Biology. 10, p. - 15 p., 36.Research output: Contribution to journal › Article › peer-review
53 Citations (Scopus) -
2011
The TFIIH subunit Tfb3 regulates cullin neddylation
Rabut, G., Le Dez, G., Verma, R., Makhnevych, T., Knebel, A., Kurz, T., Boone, C., Deshaies, R. J. & Peter, M., 5 Aug 2011, In: Molecular Cell. 43, 3, p. 488-495 8 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus) -
2008
p53-driven apoptosis limits centrosome amplification and genomic instability downstream of NPM1 phosphorylation
Cuomo, M. E., Knebel, A., Morrice, N., Paterson, H., Cohen, P. & Mittnacht, S., Jun 2008, In: Nature Cell Biology. 10, 6, p. 723-730 8 p.Research output: Contribution to journal › Article › peer-review
48 Citations (Scopus) -
2007
LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity
Jaleel, M., Nichols, R. J., Deak, M., Campbell, D. G., Gillardon, F., Knebel, A. & Alessi, D. R., 2007, In: Biochemical Journal. 405, 2, p. 307-317 11 p.Research output: Contribution to journal › Article › peer-review
446 Citations (Scopus) -
2005
Regulation of microfilament organization by Kaposi sarcoma-associated herpes virus-cyclin·CDK6 phosphorylation of caldesmon
Cuomo, M. E., Knebel, A., Platt, G., Morrice, N., Cohen, P. & Mittnacht, S. (Lead / Corresponding author), 28 Oct 2005, In: Journal of Biological Chemistry. 280, 43, p. 35844-35858 15 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Citations (Scopus) -
The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ
Eyers, C. E., McNeill, H., Knebel, A., Morrice, N., Arthur, S. J. C., Cuenda, A. & Cohen, P. (Lead / Corresponding author), 1 Jul 2005, In: Biochemical Journal. 389, 1, p. 127-135 9 p.Research output: Contribution to journal › Article › peer-review
52 Citations (Scopus) -
The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells
Cartlidge, R. A., Knebel, A., Peggie, M., Alexandrov, A., Phizicky, E. M. & Cohen, P., May 2005, In: The EMBO Journal. 24, 9, p. 1696-1705 10 p.Research output: Contribution to journal › Article › peer-review
82 Citations (Scopus) -
2004
A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs
McNeill, H., Knebel, A., Arthur, J. S. C., Cuenda, A. & Cohen, P., 1 Dec 2004, In: Biochemical Journal. 384, Pt 2, p. 391-400 10 p.Research output: Contribution to journal › Article › peer-review
60 Citations (Scopus)