Baragana, Beatriz

Medicinal Chemist, Biological Chemistry and Drug Discovery

Source: Scopus
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1 Active

Genetic Validation of a Promising Drug Target for Cryptosporidiosis
Baragana, B., Gilbert, I., Pawlowic, M. & Wyllie, S.
Carnegie Trust for the Universities of Scotland
20/08/19 → 19/02/21
Project: Research

349 Citations
8 h-Index
12 Article
1 Meeting abstract
1 Review article
1 Patent

IDENTIFICATION OF THE PLASMODIUM FALCIPARUM ACETYL-COA SYNTHETASE AS AN EMERGING ANTIPLASMODIAL DRUG TARGET
Summers, R. L., Vanaerschot, M., Murithi, J. M., Pasaje, C. F., Luth, M. R., Magistrado-Coxen, P., Carpenter, E. F., Bath, J., Pisco, J. P., Punekar, A. S., Baragana, B., Gilbert, I. H., Munro, J. T., Llinas, M., Niles, J. C., Ottilie, S., Winzeler, E. A., Lee, M. C., Fidock, D. A., Lukens, A. K. & 1 others, Wirth, D. F., Nov 2019, In : American Journal of Tropical Medicine and Hygiene. 101, 5 Suppl. 1, p. 476-477 2 p., 1555.
Research output: Contribution to journal › Meeting abstract › peer-review
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis
Baragaña, B., Forte, B., Choi, R., Nakazawa Hewitt, S., Bueren-Calabuig, J. A., Pisco, J. P., Peet, C., Dranow, D. M., Robinson, D. A., Jansen, C., Norcross, N. R., Vinayak, S., Anderson, M., Brooks, C. F., Cooper, C. A., Damerow, S., Delves, M., Dowers, K., Duffy, J., Edwards, T. E. & 57 others, Hallyburton, I., Horst, B. G., Hulverson, M. A., Ferguson, L., Jiménez-Díaz, M. B., Jumani, R. S., Lorimer, D. D., Love, M. S., Maher, S., Matthews, H., McNamara, C. W., Miller, P., O'Neill, S., Ojo, K. K., Osuna-Cabello, M., Pinto, E., Post, J., Riley, J., Rottmann, M., Sanz, L. M., Scullion, P., Sharma, A., Shepherd, S. M., Shishikura, Y., Simeons, F. R. C., Stebbins, E. E., Stojanovski, L., Straschil, U., Tamaki, F. K., Tamjar, J., Torrie, L. S., Vantaux, A., Witkowski, B., Wittlin, S., Yogavel, M., Zuccotto, F., Angulo-Barturen, I., Sinden, R., Baum, J., Gamo, F-J., Mäser, P., Kyle, D. E., Winzeler, E. A., Myler, P. J., Wyatt, P. G., Floyd, D., Matthews, D., Sharma, A., Striepen, B., Huston, C. D., Gray, D. W., Fairlamb, A. H., Pisliakov, A. V., Walpole, C., Read, K. D., Van Voorhis, W. C. & Gilbert, I. H., 2 Apr 2019, In : Proceedings of the National Academy of Sciences. 116, 14, p. 7015-7020 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
20 Citations (Scopus)

274 Downloads (Pure)
Substituted Aminoacetamides as Novel Leads for Malaria Treatment
Norcross, N., Wilson, C., Baragana, B., Hallyburton, I., Osuna-Cabello, M., Norval, S., Riley, J., Fletcher, D., Sinden, R., Delves, M. J., Ruecker, A., Duffy, S., Meister, S., Antonova-Koch, Y., Crespo, B., de Cózar, C., Sanz, L., Gamo, F-J., Avery, V. M., Frearson, J. A. & 8 others, Gray, D., Fairlamb, A., Winzeler, E. A., Waterson, D., Campbell, S. F., Willis, P., Read, K. & Gilbert, I., 17 Jul 2019, In : ChemMedChem. 14, 14, p. 1329-1335 7 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
2 Citations (Scopus)

55 Downloads (Pure)
Validation of Plasmodium falciparum dUTPase as the target of 5'-tritylated deoxyuridine analogues with anti-malarial activity
Pérez-Moreno, G., Sánchez-Carrasco, P., Ruiz-Pérez, L. M., Johansson, N. G., Müller, S., Baragaña, B., Hampton, S. E., Gilbert, I. H., Kaiser, M., Sarkar, S., Pandurangan, T., Kumar, V. & González-Pacanowska, D., 3 Dec 2019, In : Malaria Journal. 18, p. 1-12 12 p., 392.
Research output: Contribution to journal › Article › peer-review

Open Access
File
57 Downloads (Pure)
Challenges and recent progress in drug discovery for tropical diseases
De Rycker, M., Baragaña, B., Duce, S. L. & Gilbert, I. H., 25 Jul 2018, In : Nature. 559, 7715, p. 498-506 9 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
39 Citations (Scopus)

231 Downloads (Pure)

Genetic Validation of a Promising Drug Target for Cryptosporidiosis

IDENTIFICATION OF THE PLASMODIUM FALCIPARUM ACETYL-COA SYNTHETASE AS AN EMERGING ANTIPLASMODIAL DRUG TARGET

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Substituted Aminoacetamides as Novel Leads for Malaria Treatment

Validation of Plasmodium falciparum dUTPase as the target of 5'-tritylated deoxyuridine analogues with anti-malarial activity

Challenges and recent progress in drug discovery for tropical diseases