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Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Proteins Medicine & Life Sciences
Trypanosoma brucei brucei Medicine & Life Sciences
Biosynthesis Chemical Compounds
Enzymes Medicine & Life Sciences
Crystal structure Chemical Compounds
Leishmania major Medicine & Life Sciences
Staphylococcus aureus Medicine & Life Sciences
Serratia marcescens Medicine & Life Sciences

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Research Output 1996 2018

GABA-A Receptors
Amino Acid Substitution
gamma-Aminobutyric Acid
Substitution reactions
Chemical activation

Structure and activity of ChiX, a peptidoglycan hydrolase required for chitinase secretion by Serratia marcescens

Owen, R. A., Fyfe, P. K., Lodge, A., Biboy, J., Vollmer, W., Hunter, W. N. & Sargent, F., 23 Jan 2018, In : Biochemical Journal. 475, 2, p. 415-428 14 p.

Research output: Contribution to journalArticle

Open Access
File
N-Acetylmuramoyl-L-alanine Amidase
Chitinases
Serratia marcescens
Machinery
Peptidoglycan
1 Citations

An improved model of the Trypanosoma brucei CTP synthetase glutaminase domain-acivicin complex

de Souza, J. O., Dawson, A. & Hunter, W. N., 20 Apr 2017, In : ChemMedChem. 12, 8, p. 577-579 3 p.

Research output: Contribution to journalArticle

Open Access
File
CTP synthetase
acivicin
Glutaminase
Trypanosoma brucei brucei
Neglected Diseases
2 Citations

Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery

Linciano, P., Dawson, A., Pöhner, I., Costa, D. M., Sá, M. S., Cordeiro Da Silva, A., Luciani, R., Gul, S., Witt, G., Ellinger, B., Kuzikov, M., Gribbon, P., Reinshagen, J., Wolf, M., Behrens, B., Hannaert, V., Michels, P. A. M., Nerini, E., Pozzi, C., di Pisa, F. & 19 othersLandi, G., Santarem, N., Ferrari, S., Saxena, P., Lazzari, S., Cannazza, G., Freitas-Junior, L. H., Moraes, C. B., Pascoalino, B. S., Alcântara, L. M., Bertolacini, C. P., Fontana, V., Wittig, U., Müller, W., Wade, R. C., Hunter, W. N., Mangani, S., Costantino, L. & Costi, M. P., 30 Sep 2017, In : ACS Omega. 2, 9, p. 5666-5683 18 p.

Research output: Contribution to journalArticle

Open Access
File
2-amino-1,3,4-thiadiazole
Thiadiazoles
Scaffolds
Methotrexate
Folic Acid Antagonists
4 Citations

Mutations in POGLUT1 in Galli-Galli/Dowling Degos-disease

Wilson, N. J., Cole, C., Kroboth, K., Hunter, W. N., Mann, J. A., Irwin McLean, W. H., Kernland Lang, K., Beltraminelli, H., Sabroe, R. A., Tiffin, N., Sobey, G. J., Borradori, L., Simpson, E. & Smith, F. J. D., Jan 2017, In : British Journal of Dermatology. 176, 1, p. 270-274 5 p.

Research output: Contribution to journalLetter

Open Access
File
Glucosyltransferases
Genetic Databases
Mutation
Proteins
Keratin-5

Thesis

Assessment of potential antibacterial drug targets

Author: Diaz Saez, L., 2016

Supervisor: Hunter, W. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Development of a high throughput ligand screening method and structural studies of pentameric ligand gated ion channels.

Author: Trumper, P., 2014

Supervisor: Hunter, W. (Supervisor) & Hales, T. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Structural characterization of bacterial membrane proteins via molecular dynamics simulations and electrophysiology

Author: Tamburrino, G., 2018

Supervisor: Zachariae, U. (Supervisor) & Hunter, W. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Structural examination of trypanosomatid tubulin-binding cofactors and pteridine reductase 1 inhibition

Author: Barrack, K. L., 2013

Supervisor: Hunter, W. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Structural studies to inform antimicrobial drug discovery and the basis of immunity against T6 effectors

Author: O'Rourke, P., 2013

Supervisor: Hunter, W. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File