Blair Smith

2020

Translating clinical trials into improved real-world management of pain: Convergence of translational, population-based and primary care research

Gilron, I., Blyth, F. M. & Smith, B., Jan 2020, In : Pain. 161, 1, p. 36-42 7 p.

Research output: Contribution to journal › Article

2019

51 Downloads (Pure)

A catalog of genetic loci associated with kidney function from analyses of a million individuals

LifeLines Cohort Study, Wuttke, M., Li, Y., Li, M., Sieber, K. B., Feitosa, M. F., Gorski, M., Tin, A., Wang, L., Chu, A. Y., Hoppmann, A., Kirsten, H., Giri, A., Chai, J-F., Sveinbjornsson, G., Tayo, B. O., Nutile, T., Fuchsberger, C., Marten, J., Cocca, M. & 33 others, Ghasemi, S., Xu, Y., Horn, K., Noce, D., van der Most, P. J., Sedaghat, S., Yu, Z., Akiyama, M., Afaq, S., Ahluwalia, T. S., Almgren, P., Amin, N., Ärnlöv, J., Bakker, S. J. L., Bansal, N., Baptista, D., Bergmann, S., Biggs, M. L., Biino, G., Boehnke, M., Boerwinkle, E., Boissel, M., Bottinger, E. P., Boutin, T. S., Brenner, H., Brumat, M., Burkhardt, R., Butterworth, A. S., Campana, E., Campbell, A., Smith, B. H., Köttgen, A. & Pattaro, C., Jun 2019, In : Nature Genetics. 51, 6, p. 957-972 16 p.

Research output: Contribution to journal › Article

Open Access

File

Genetic Loci

Kidney

Glomerular Filtration Rate

Chronic Renal Insufficiency

Translational Medical Research

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

LifeLines Cohort Study, Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D. & 40 others, Marten, J., Musani, S. K., Kilpeläinen, T. O., Richard, M. A., Aslibekyan, S., Bartz, T. M., Dorajoo, R., Li, C., Liu, Y., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., Connell, J. M., Smith, B. H., Rotter, J. I., Franks, P. W., Rice, K., Elliott, P., Caulfield, M. J., Gauderman, W. J., Munroe, P. B., Rao, D. C. & Morrison, A. C., 1 Aug 2019, In : Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.

Research output: Contribution to journal › Article

Arterial Pressure

Smoking

Genome

Blood Pressure

Genes

42 Downloads (Pure)

Associations of autozygosity with a broad range of human phenotypes

Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., Mattsson, H., Barnes, C. L. K., Lin, K., Zhao, J. H., Deelen, P., Rohde, R., Schurmann, C., Guo, X., Giulianini, F., Zhang, W., Medina-Gomez, C., Karlsson, R., Bao, Y., Bartz, T. M. & 416 others, Baumbach, C., Biino, G., Bixley, M. J., Brumat, M., Chai, J-F., Corre, T., Cousminer, D. L., Dekker, A. M., Eccles, D. A., van Eijk, K. R., Fuchsberger, C., Gao, H., Germain, M., Gordon, S. D., de Haan, H. G., Harris, S. E., Hofer, E., Huerta-Chagoya, A., Igartua, C., Jansen, I. E., Jia, Y., Kacprowski, T., Karlsson, T., Kleber, M. E., Li, S. A., Li-Gao, R., Mahajan, A., Matsuda, K., Meidtner, K., Meng, W., Montasser, M. E., van der Most, P. J., Munz, M., Nutile, T., Palviainen, T., Prasad, G., Prasad, R. B., Priyanka, T. D. S., Rizzi, F., Salvi, E., Sapkota, B. R., Shriner, D., Skotte, L., Smart, M. C., Smith, A. V., van der Spek, A., Spracklen, C. N., Strawbridge, R. J., Tajuddin, S. M., Trompet, S., Turman, C., Verweij, N., Viberti, C., Wang, L., Warren, H. R., Wootton, R. E., Yanek, L. R., Yao, J., Yousri, N. A., Zhao, W., Adeyemo, A. A., Afaq, S., Aguilar-Salinas, C. A., Akiyama, M., Albert, M. L., Allison, M. A., Alver, M., Aung, T., Azizi, F., Bentley, A. R., Boeing, H., Boerwinkle, E., Borja, J. B., de Borst, G. J., Bottinger, E. P., Broer, L., Campbell, H., Chanock, S., Chee, M-L., Chen, G., Chen, Y-D. I., Chen, Z., Chiu, Y-F., Cocca, M., Collins, F. S., Concas, M. P., Corley, J., Cugliari, G., van Dam, R. M., Damulina, A., Daneshpour, M. S., Day, F. R., Delgado, G. E., Dhana, K., Doney, A. S. F., Dörr, M., Doumatey, A. P., Dzimiri, N., Ebenesersdóttir, S. S., Elliott, J., Elliott, P., Ewert, R., Felix, J. F., Fischer, K., Freedman, B. I., Girotto, G., Goel, A., Gögele, M., Goodarzi, M. O., Graff, M., Granot-Hershkovitz, E., Grodstein, F., Guarrera, S., Gudbjartsson, D. F., Guity, K., Gunnarsson, B., Guo, Y., Hagenaars, S. P., Haiman, C. A., Halevy, A., Harris, T. B., Hedayati, M., van Heel, D. A., Hirata, M., Höfer, I., Hsiung, C. A., Huang, J., Hung, Y-J., Ikram, M. A., Jagadeesan, A., Jousilahti, P., Kamatani, Y., Kanai, M., Kerrison, N. D., Kessler, T., Khaw, K-T., Khor, C. C., de Kleijn, D. P. V., Koh, W-P., Kolcic, I., Kraft, P., Krämer, B. K., Kutalik, Z., Kuusisto, J., Langenberg, C., Launer, L. J., Lawlor, D. A., Lee, I-T., Lee, W-J., Lerch, M. M., Li, L., Liu, J., Loh, M., London, S. J., Loomis, S., Lu, Y., Luan, J., Mägi, R., Manichaikul, A. W., Manunta, P., Másson, G., Matoba, N., Mei, X. W., Meisinger, C., Meitinger, T., Mezzavilla, M., Milani, L., Millwood, I. Y., Momozawa, Y., Moore, A., Morange, P-E., Moreno-Macías, H., Mori, T. A., Morrison, A. C., Muka, T., Murakami, Y., Murray, A. D., de Mutsert, R., Mychaleckyj, J. C., Nalls, M. A., Nauck, M., Neville, M. J., Nolte, I. M., Ong, K. K., Orozco, L., Padmanabhan, S., Pálsson, G., Pankow, J. S., Pattaro, C., Pattie, A., Polasek, O., Poulter, N., Pramstaller, P. P., Quintana-Murci, L., Räikkönen, K., Ralhan, S., Rao, D. C., van Rheenen, W., Rich, S. S., Ridker, P. M., Rietveld, C. A., Robino, A., van Rooij, F. J. A., Ruggiero, D., Saba, Y., Sabanayagam, C., Sabater-Lleal, M., Sala, C. F., Salomaa, V., Sandow, K., Schmidt, H., Scott, L. J., Scott, W. R., Sedaghati-Khayat, B., Sennblad, B., van Setten, J., Sever, P. J., Sheu, W. H-H., Shi, Y., Shrestha, S., Shukla, S. R., Sigurdsson, J. K., Sikka, T. T., Singh, J. R., Smith, B. H., Stančáková, A., Stanton, A., Starr, J. M., Stefansdottir, L., Straker, L., Sulem, P., Sveinbjornsson, G., Swertz, M. A., Taylor, A. M., Taylor, K. D., Terzikhan, N., Tham, Y-C., Thorleifsson, G., Thorsteinsdottir, U., Tillander, A., Tracy, R. P., Tusié-Luna, T., Tzoulaki, I., Vaccargiu, S., Vangipurapu, J., Veldink, J. H., Vitart, V., Völker, U., Vuoksimaa, E., Wakil, S. M., Waldenberger, M., Wander, G. S., Wang, Y. X., Wareham, N. J., Wild, S., Yajnik, C. S., Yuan, J-M., Zeng, L., Zhang, L., Zhou, J., Amin, N., Asselbergs, F. W., Bakker, S. J. L., Becker, D. M., Lehne, B., Bennett, D. A., van den Berg, L. H., Berndt, S. I., Bharadwaj, D., Bielak, L. F., Bochud, M., Boehnke, M., Bouchard, C., Bradfield, J. P., Brody, J. A., Campbell, A., Carmi, S., Caulfield, M. J., Cesarini, D., Chambers, J. C., Chandak, G. R., Cheng, C-Y., Ciullo, M., Cornelis, M., Cusi, D., Smith, G. D., Deary, I. J., Dorajoo, R., van Duijn, C. M., Ellinghaus, D., Erdmann, J., Eriksson, J. G., Evangelou, E., Evans, M. K., Faul, J. D., Feenstra, B., Feitosa, M., Foisy, S., Franke, A., Friedlander, Y., Gasparini, P., Gieger, C., Gonzalez, C., Goyette, P., Grant, S. F. A., Griffiths, L. R., Groop, L., Gudnason, V., Gyllensten, U., Hakonarson, H., Hamsten, A., van der Harst, P., Heng, C-K., Hicks, A. A., Hochner, H., Huikuri, H., Hunt, S. C., Jaddoe, V. W. V., De Jager, P. L., Johannesson, M., Johansson, Å., Jonas, J. B., Jukema, J. W., Junttila, J., Kaprio, J., Kardia, S. L. R., Karpe, F., Kumari, M., Laakso, M., van der Laan, S. W., Lahti, J., Laudes, M., Lea, R. A., Lieb, W., Lumley, T., Martin, N. G., März, W., Matullo, G., McCarthy, M. I., Medland, S. E., Merriman, T. R., Metspalu, A., Meyer, B. F., Mohlke, K. L., Montgomery, G. W., Mook-Kanamori, D., Munroe, P. B., North, K. E., Nyholt, D. R., O'connell, J. R., Ober, C., Oldehinkel, A. J., Palmas, W., Palmer, C., Pasterkamp, G. G., Patin, E., Pennell, C. E., Perusse, L., Peyser, P. A., Pirastu, M., Polderman, T. J. C., Porteous, D. J., Posthuma, D., Psaty, B. M., Rioux, J. D., Rivadeneira, F., Rotimi, C., Rotter, J. I., Rudan, I., Den Ruijter, H. M., Sanghera, D. K., Sattar, N., Schmidt, R., Schulze, M. B., Schunkert, H., Scott, R. A., Shuldiner, A. R., Sim, X., Small, N., Smith, J. A., Sotoodehnia, N., Tai, E-S., Teumer, A., Timpson, N. J., Toniolo, D., Tregouet, D-A., Tuomi, T., Vollenweider, P., Wang, C. A., Weir, D. R., Whitfield, J. B., Wijmenga, C., Wong, T-Y., Wright, J., Yang, J., Yu, L., Zemel, B. S., Zonderman, A. B., Perola, M., Magnusson, P. K. E., Uitterlinden, A. G., Kooner, J. S., Chasman, D. I., Loos, R. J. F., Franceschini, N., Franke, L., Haley, C. S., Hayward, C., Walters, R. G., Perry, J. R. B., Esko, T., Helgason, A., Stefansson, K., Joshi, P. K., Kubo, M. & Wilson, J. F., 31 Oct 2019, In : Nature Communications. 10, 1, p. 1-17 17 p., 4957.

Research output: Contribution to journal › Article

Open Access

File

phenotype

Phenotype

Inbreeding

social factors

fertility

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

Understanding Society Scientific Group, Shrine, N., Guyatt, A. L., Erzurumluoglu, A. M., Jackson, V. E., Hobbs, B. D., Melbourne, C. A., Batini, C., Fawcett, K. A., Song, K., Sakornsakolpat, P., Li, X., Boxall, R., Reeve, N. F., Obeidat, M., Zhao, J. H., Wielscher, M., Weiss, S., Kentistou, K. A., Cook, J. P. & 33 others, Sun, B. B., Zhou, J., Hui, J., Karrasch, S., Imboden, M., Harris, S. E., Marten, J., Enroth, S., Kerr, S. M., Surakka, I., Vitart, V., Lehtimäki, T., Allen, R. J., Bakke, P. S., Beaty, T. H., Bleecker, E. R., Bossé, Y., Brandsma, C-A., Chen, Z., Crapo, J. D., Danesh, J., DeMeo, D. L., Dudbridge, F., Ewert, R., Gieger, C., Gulsvik, A., Hansell, A. L., Hao, K., Hoffman, J. D., Hokanson, J. E., Smith, B. H., Tobin, M. D. & Wain, L. V., Jun 2019, In : Nature Genetics. 51, 6, p. 1067 1 p.

Research output: Contribution to journal › Article

Chronic Obstructive Pulmonary Disease

Lung

4 Citations (Scopus)

Chronic pain: a review of its epidemiology and associated factors in population-based studies

Mills, S. E. E., Nicolson, K. P. & Smith, B. H., 1 Aug 2019, In : British Journal of Anaesthesia. 123, 2, p. e273-e283 11 p.

Research output: Contribution to journal › Article

Chronic Pain

Epidemiology

Population

Life Style

Demography

61 Citations (Scopus)

106 Downloads (Pure)

Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11)

Treede, R-D., Rief, W., Barke, A., Aziz, Q., Bennett, M. I., Benoliel, R., Cohen, M., Evers, S., Finnerup, N. B., First, M. B., Giamberardino, M. A., Kaasa, S., Korwisi, B., Kosek, E., Lavandʼhomme, P., Nicholas, M., Perrot, S., Scholz, J., Schug, S., Smith, B. H. & 3 others, Svensson, P., Vlaeyen, J. W. S. & Wang, S-J., 1 Jan 2019, In : Pain. 160, 1, p. 19-27 9 p.

Research output: Contribution to journal › Review article

Open Access

File

International Classification of Diseases

Chronic Pain

Pain

Visceral Pain

Musculoskeletal Pain

1 Citation (Scopus)

Comparison of psychiatric comorbidity in treatment‐seeking, opioid‐dependent patients with versus without chronic pain

Higgins, C., Smith, B. H. & Matthews, K., 6 Aug 2019, In : Addiction. 10 p.

Research output: Contribution to journal › Article

Chronic Pain

Psychiatry

Comorbidity

Scotland

Opioid Analgesics

1 Citation (Scopus)

42 Downloads (Pure)

Evidence of opioid-induced hyperalgesia in clinical populations after chronic opioid exposure: a systematic review and meta-analysis

Higgins, C., Smith, B. & Matthews, K., Jun 2019, In : British Journal of Anaesthesia. 122, 6, p. e114-e126 13 p.

Research output: Contribution to journal › Article

Open Access

File

Hyperalgesia

Opioid Analgesics

Meta-Analysis

Population

Pain

24 Downloads (Pure)

Factors affecting use of unscheduled care for people with advanced cancer: a retrospective cohort study in Scotland

Mills, S., Buchanan, D., Guthrie, B., Donnan, P. & Smith, B., Dec 2019, In : British Journal of General Practice. 69, 689, p. e860-e868 9 p.

Research output: Contribution to journal › Article

Open Access

File

Scotland

Cohort Studies

Retrospective Studies

Neoplasms

Demography

30 Downloads (Pure)

Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

Clarke, T-K., Adams, M. J., Howard, D. M., Xia, C., Davies, G., Hayward, C., Campbell, A., Padmanabhan, S., Smith, B., Murray, A., Porteous, D., Deary, I. J. & McIntosh, A. M., 25 Nov 2019, In : Molecular Psychiatry. 11 p.

Research output: Contribution to journal › Article

Open Access

File

Smoking

Alcohols

Population

Mating Factor

Single Nucleotide Polymorphism

41 Downloads (Pure)

Genetic correlations between pain phenotypes and depression and neuroticism

Meng, W., Adams, M. J., Reel, P., Rajendrakumar, A., Huang, Y., Deary, I. J., Palmer, C. N. A., McIntosh, A. M. & Smith, B. H., 29 Oct 2019, In : European Journal of Human Genetics. 9 p.

Research output: Contribution to journal › Article

Open Access

File

Depression

Phenotype

Pain

Linkage Disequilibrium

Major Depressive Disorder

21 Citations (Scopus)

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

Understanding Society Scientific Group, Sakornsakolpat, P., Prokopenko, D., Lamontagne, M., Reeve, N. F., Guyatt, A. L., Jackson, V. E., Shrine, N., Qiao, D., Bartz, T. M., Kim, D. K., Lee, M. K., Latourelle, J. C., Li, X., Morrow, J. D., Obeidat, M., Wyss, A. B., Bakke, P., Barr, R. G., Beaty, T. H. & 35 others, Belinsky, S. A., Brusselle, G. G., Crapo, J. D., de Jong, K., DeMeo, D. L., Fingerlin, T. E., Gharib, S. A., Gulsvik, A., Hall, I. P., Hokanson, J. E., Kim, W. J., Lomas, D. A., London, S. J., Meyers, D. A., O’Connor, G. T., Rennard, S. I., Schwartz, D. A., Sliwinski, P., Sparrow, D., Strachan, D. P., Tal-Singer, R., Tesfaigzi, Y., Vestbo, J., Vonk, J. M., Yim, J. J., Zhou, X., Bossé, Y., Manichaikul, A., Lahousse, L., Silverman, E. K., Boezen, H. M., Wain, L. V., Tobin, M. D., Hobbs, B. D. & Cho, M. H., 1 Mar 2019, In : Nature Genetics. 51, 3, p. 494-505 12 p.

Research output: Contribution to journal › Article

Chronic Obstructive Pulmonary Disease

Phenotype

Lung

Genetic Loci

Genetic Heterogeneity

18 Citations (Scopus)

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

23andMe Research Team, Karlsson Linnér, R., Biroli, P., Kong, E., Meddens, S. F. W., Wedow, R., Fontana, M. A., Lebreton, M., Tino, S. P., Abdellaoui, A., Hammerschlag, A. R., Nivard, M. G., Okbay, A., Rietveld, C. A., Timshel, P. N., Trzaskowski, M., Vlaming, R. D., Zünd, C. L., Bao, Y., Buzdugan, L. & 22 others, Caplin, A. H., Chen, C. Y., Eibich, P., Fontanillas, P., Gonzalez, J. R., Joshi, P. K., Karhunen, V., Kleinman, A., Levin, R. Z., Lill, C. M., Meddens, G. A., Muntané, G., Sanchez-Roige, S., Rooij, F. J. V., Taskesen, E., Wu, Y., Zhang, F., Auton, A., Boardman, J. D., Clark, D. W., Conlin, A. & Beauchamp, J. P., 2019, In : Nature Genetics. 51, 2, p. 245-257 13 p.

Research output: Contribution to journal › Article

Genetic Loci

Genome-Wide Association Study

Single Nucleotide Polymorphism

Computational Biology

Synaptic Transmission

6 Citations (Scopus)

108 Downloads (Pure)

Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

Wigmore, E. M., Hafferty, J. D., Hall, L. S., Howard, D. M., Clarke, T-K., Fabbri, C., Lewis, C. M., Uher, R., Navrady, L., Adams, M. J., Zeng, Y., Campbell, A., Gibson, J., Thomson, P. A., Hayward, C., Smith, B., Hocking, L. J., Padmanabhan, S., Deary, I. J., Porteous, D. J. & 4 others, Mors, O., Mattheisen, M., Nicodemus, K. K. & McIntosh, A. M., 31 Jan 2019, In : Pharmacogenomics Journal. 13 p.

Research output: Contribution to journal › Article

Open Access

File

Genome-Wide Association Study

Antidepressive Agents

Health Services

Prescriptions

Meta-Analysis

56 Downloads (Pure)

Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank

Meng, W., Adams, M. J., Palmer, C. N. A., 23andMe Research Team, Shi, J., Auton, A., Ryan, K. A., Jordan, J. M., Mitchell, B. D., Jackson, R. D., Yau, M. S., McIntosh, A. M. & Smith, B. H., 28 Aug 2019, In : Communications Biology. 2, p. 1-8 8 p., 321.

Research output: Contribution to journal › Article

Open Access

File

Genome-Wide Association Study

Knee

Pain

Osteoarthritis

Knee Osteoarthritis

Implementation of Patient-Reported Outcomes (PROMs) from specialist pain clinics in England and Wales: experience from a nationwide study

Price, C., Williams, A. C. D. C., Smith, B. H. & Bottle, A., 1 Aug 2019, In : European Journal of Pain. 23, 7, p. 1368-1377 10 p.

Research output: Contribution to journal › Article

Pain Clinics

Wales

England

Quality of Life

Delivery of Health Care

69 Downloads (Pure)

Insulin resistance: Genetic associations with depression and cognition in population based cohorts

Frangou, S., Shirali, M., Adams, M. J., Howard, D. M., Gibson, J., Hall, L. S., Smith, B. H., Padmanabhan, S., Murray, A. D., Porteous, D. J., Haley, C. S., Deary, I. J., Clarke, T-K. & McIntosh, A. M., Jun 2019, In : Experimental Neurology. 316, p. 20-26 7 p.

Research output: Contribution to journal › Article

Open Access

File

Cognition

Insulin Resistance

Depression

Population

Intelligence

3 Citations (Scopus)

41 Downloads (Pure)

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

UK10K Consortium, 21 Jan 2019, In : Nature Communications. 10, 1, 357.

Research output: Contribution to journal › Article

Open Access

File

circumferences

Head

low frequencies

Genetic Models

Human Development

5 Citations (Scopus)

23 Downloads (Pure)

Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

InterAct Consortium, LifeLines Cohort Study, de Vries, P. S., Brown, M. R., Bentley, A. R., Sung, Y. J., Winkler, T. W., Ntalla, I., Schwander, K., Kraja, A. T., Guo, X., Franceschini, N., Cheng, C-Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F., Richard, M. A. & 34 others, Noordam, R., Aschard, H., Bartz, T. M., Bielak, L. F., Deng, X., Dorajoo, R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Evangelou, E., Graff, M., Alver, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., Hartwig, F. P., He, M., Horimoto, A. R. V. R., Hsu, F-C., Jackson, A. U., Kasturiratne, A., Komulainen, P., Connell, J. M., Smith, B. H., Rao, D. C. & Morrison, A. C., 1 Jun 2019, In : American Journal of Epidemiology. 188, 6, p. 1033-1054 22 p.

Research output: Contribution to journal › Article

Open Access

File

Genome-Wide Association Study

Alcohols

Lipids

Vascular Endothelial Growth Factor B

Proprotein Convertases

18 Citations (Scopus)

138 Downloads (Pure)

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

Understanding Society Scientific Group, Shrine, N., Guyatt, A. L., Erzurumluoglu, A. M., Jackson, V. E., Hobbs, B. D., Melbourne, C. A., Batini, C., Fawcett, K. A., Song, K., Sakornsakolpat, P., Li, X., Boxall, R., Reeve, N. F., Obeidat, M., Zhao, J. H., Wielscher, M., Weiss, S., Kentistou, K. A., Cook, J. P. & 33 others, Sun, B. B., Zhou, J., Hui, J., Karrasch, S., Imboden, M., Harris, S. E., Marten, J., Enroth, S., Kerr, S. M., Surakka, I., Vitart, V., Lehtimäki, T., Allen, R. J., Bakke, P. S., Beaty, T. H., Bleecker, E. R., Bossé, Y., Brandsma, C-A., Chen, Z., Crapo, J. D., Danesh, J., DeMeo, D. L., Dudbridge, F., Ewert, R., Gieger, C., Gulsvik, A., Hansell, A. L., Hao, K., Hoffman, J. D., Hokanson, J. E., Smith, B. H., Tobin, M. D. & Wain, L. V., Mar 2019, In : Nature Genetics. 51, 3, p. 481-493 13 p.

Research output: Contribution to journal › Article

Open Access

File

Chronic Obstructive Pulmonary Disease

Lung

Genome-Wide Association Study

Mortality

Pharmaceutical Preparations

2 Citations (Scopus)

Opioid prescribing is rising in many countries

Smith, B. H., Fletcher, E. H. & Colvin, L. A., 17 Oct 2019, In : BMJ. 367, p. 1-2 2 p., l5823.

Research output: Contribution to journal › Editorial

Chronic Pain

Opioid Analgesics

78 Downloads (Pure)

PALS: peer support for community dwelling older people with chronic low back pain: a feasibility and acceptability study

Cooper, K., Schofield, P., Smith, B. H. & Klein, S., 4 Feb 2019, In : Physiotherapy (United Kingdom). 9 p.

Research output: Contribution to journal › Article

Open Access

File

Independent Living

Feasibility Studies

Low Back Pain

Volunteers

Outcome Assessment (Health Care)

12 Citations (Scopus)

119 Downloads (Pure)

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

T2D-Genes Consortium, The MAGIC Investigators, CHD Exome+ Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, ReproGen Consortium, Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., Turcot, V., Auer, P. L., Fine, R. S., Guo, X., Schurmann, C., Lempradl, A. & 40 others, Marouli, E., Mahajan, A., Winkler, T. W., Locke, A. E., Medina-Gomez, C., Esko, T., Vedantam, S., Giri, A., Lo, K. S., Alfred, T., Mudgal, P., Ng, M. C. Y., Heard-Costa, N. L., Feitosa, M. F., Manning, A. K., Willems, S. M., Sivapalaratnam, S., Abecasis, G., Alam, D. S., Allison, M., Amouyel, P., Arzumanyan, Z., Balkau, B., Bastarache, L., Bergmann, S., Bielak, L. F., Blüher, M., Boehnke, M., Boeing, H., Boerwinkle, E., Böger, C. A., Bork-Jensen, J., Evangelou, E., Li, J., Morris, A. P., Smith, B. H., Smith, J. A., Wood, A. R., North, K. E. & Lindgren, C. M., Mar 2019, In : Nature Genetics. 51, 3, p. 452-469 18 p.

Research output: Contribution to journal › Article

Open Access

File

Body Fat Distribution

Homeostasis

Lipids

Fats

Genes

Reply to Henningsen et al.

Rief, W., Korwisi, B., Nicholas, M., Vlaeyen, J. W. S., Smith, B. H., First, M. B., Kosek, E., Barke, A. & Treede, R-D., Jul 2019, In : Pain. 160, 7, p. 1683-1685 3 p.

Research output: Contribution to journal › Letter

3 Citations (Scopus)

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

Tin, A., Marten, J., Halperin Kuhns, V. L., Li, Y., Wuttke, M., Kirsten, H., Sieber, K. B., Qiu, C., Gorski, M., Yu, Z., Giri, A., Sveinbjornsson, G., Li, M., Chu, A. Y., Hoppmann, A., O'Connor, L. J., Prins, B., Nutile, T., Noce, D., Akiyama, M. & 31 others, Cocca, M., Ghasemi, S., van der Most, P. J., Horn, K., Xu, Y., Fuchsberger, C., Sedaghat, S., Afaq, S., Amin, N., Ärnlöv, J., Bakker, S. J. L., Bansal, N., Baptista, D., Bergmann, S., Biggs, M. L., Biino, G., Boerwinkle, E., Bottinger, E. P., Boutin, T. S., Brumat, M., Burkhardt, R., Campana, E., Campbell, A., Campbell, H., Carroll, R. J., Catamo, E., Chambers, J. C., Ciullo, M., Concas, M. P., Smith, B. H. & Köttgen, A., Oct 2019, In : Nature Genetics. 51, 10, p. 1459–1474 22 p.

Research output: Contribution to journal › Article

Uric Acid

Serum

Gout

Genes

Kidney

1 Citation (Scopus)

29 Downloads (Pure)

The genetics of neuropathic pain from model organisms to clinical application

Calvo, M., Davies, A. J., Hebert, H., Weir, G., Chesler, E. J., Finnerup, N. B., Smith, B. H., Neely, G., Costigan, M. & Bennett, D. L., 20 Nov 2019, In : Neuron. 104, 4, p. 637-653 17 p.

Research output: Contribution to journal › Review article

Open Access

File

Neuralgia

Clustered Regularly Interspaced Short Palindromic Repeats

Nervous System Trauma

Genetic Techniques

Pain Clinics

10 Citations (Scopus)

8 Downloads (Pure)

The IASP classification of chronic pain for ICD-11: Applicability in Primary Care

Smith, B., Fors, E. A., Korwisi, B., Barke, A., Cameron, P., Colvin, L., Richardson, C., Rief, W. & Treede, R-D., 1 Jan 2019, In : Pain. 160, 1, p. 83-87 5 p.

Research output: Contribution to journal › Review article

Open Access

File

International Classification of Diseases

Chronic Pain

Primary Health Care

Forensic Anthropology

Delivery of Health Care

22 Citations (Scopus)

9 Downloads (Pure)

The IASP classification of chronic pain for ICD-11: Chronic neuropathic pain

Scholz, J., Finnerup, N. B., Attal, N., Aziz, Q., Baron, R., Bennett, M. I., Benoliel, R., Cohen, M., Cruccu, G., Davis, K. D., Evers, S., First, M. B., Giamberardino, M. A., Hansson, P. T., Kaasa, S., Korwisi, B., Kosek, E., Lavandʼhomme, P., Nicholas, M., Nurmikko, T. J. & 13 others, Perrot, S., Raja, S. N., Rice, A. S. C., Rowbotham, M. C., Schug, S., Smipson, D. M., Smith, B., Svensson, P., Vlaeyen, J. W. S., Wang, S-J., Barke, A., Rief, W. & Treede, R-D., 1 Jan 2019, In : Pain. 160, 1, p. 53-59 7 p.

Research output: Contribution to journal › Review article

Open Access

File

Neuralgia

Chronic Pain

Pain

Postherpetic Neuralgia

Peripheral Nerve Injuries

1 Citation (Scopus)

126 Downloads (Pure)

The National Pain Audit for specialist pain services in England and Wales 2010–2014

Price, C., de C Williams, A. C., Smith, B. H. & Bottle, A., 1 Aug 2019, In : British Journal of Pain. 13, 3, p. 185-193 9 p.

Research output: Contribution to journal › Article

Open Access

File

Pain Clinics

Wales

England

Standard of Care

Quality Improvement

2018

11 Citations (Scopus)

153 Downloads (Pure)

A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N = 223,773)

Meng, W., Adams, M. J., Hebert, H. L., Deary, I. J., McIntosh, A. M. & Smith, B. H., Feb 2018, In : EBioMedicine. 28, p. 180-186 7 p.

Research output: Contribution to journal › Article

Open Access

File

Genome-Wide Association Study

Headache

Genes

Single Nucleotide Polymorphism

Brain

10 Citations (Scopus)

107 Downloads (Pure)

Association of opioid prescribing practices with chronic pain and benzodiazepine co-prescription: a primary care data linkage study

Torrance, N., Mansoor, R., Wang, H., Gilbert, S., Macfarlane, G. J., Serpell, M., Baldacchino, A., Hales, T. G., Donnan, P., Wyper, G., Smith, B. H. & Colvin, L., Jun 2018, In : British Journal of Anaesthesia. 120, 6, p. 1345-1355 11 p.

Research output: Contribution to journal › Article

Open Access

File

Information Storage and Retrieval

Benzodiazepines

Chronic Pain

Opioid Analgesics

Prescriptions

4 Citations (Scopus)

83 Downloads (Pure)

Chronic pain in families: A cross-sectional study of shared social, behavioural, and environmental influences

Generation Scotland, Campbell, P., Jordan, K. P., Smith, B. & Dunn, K. M., 1 Jan 2018, In : Pain. 159, 1, p. 41-47 7 p.

Research output: Contribution to journal › Article

Open Access

File

Chronic Pain

Cross-Sectional Studies

Family Health

Scotland

Logistic Models

9 Citations (Scopus)

174 Downloads (Pure)

Cohort Profile: Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS)

Hébert, H. L., Shepherd, B., Milburn, K., Veluchamy, A., Meng, W., Carr, F., Donnelly, L. A., Tavendale, R., Leese, G., Colhoun, H. M., Dow, E., Morris, A. D., Doney, A. S., Lang, C. C., Pearson, E. R., Smith, B. H. & Palmer, C. N. A., 1 Apr 2018, In : International Journal of Epidemiology. 47, 2, p. 380-381j 12 p.

Research output: Contribution to journal › Article

Open Access

File

1 Citation (Scopus)

220 Downloads (Pure)

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Lin, H., van Setten, J., Smith, A. V., Bihlmeyer, N. A., Warren, H. R., Brody, J. A., Radmanesh, F., Hall, L., Grarup, N., Müller-Nurasyid, M., Boutin, T., Verweij, N., Lin, H. J., Li-Gao, R., van den Berg, M. E., Marten, J., Weiss, S., Prins, B. P., Haessler, J., Lyytikäinen, L-P. & 30 others, Mei, H., Harris, T. B., Launer, L. J., Li, M., Alonso, A., Soliman, E. Z., Connell, J. M., Huang, P. L., Weng, L-C., Jameson, H. S., Hucker, W., Hanley, A., Tucker, N. R., Chen, Y-D. I., Bis, J. C., Rice, K. M., Sitlani, C. M., Kors, J. A., Xie, Z., Wen, C., Magnani, J. W., Nelson, C. P., Kanters, J. K., Sinner, M. F., Strauch, K., Peters, A., Waldenberger, M., Meitinger, T., Bork-Jensen, J. & Smith, B. H., May 2018, In : Circulation: Genomic and Precision Medicine. 11, 5, p. 1-30 30 p., e002037.

Research output: Contribution to journal › Article

Open Access

File

Genetic Loci

Sinoatrial Node

Genome-Wide Association Study

Morphogenesis

Genes

2 Citations (Scopus)

181 Downloads (Pure)

Decision Support for Diabetes in Scotland: Implementation and Evaluation of a Clinical Decision Support System

Conway, N., Adamson, K. A., Cunningham, S. G., Emslie Smith, A., Nyberg, P., Smith, B. H., Wales, A. & Wake, D. J., 1 Mar 2018, In : Journal of Diabetes Science and Technology. 12, 2, p. 381-388 8 p.

Research output: Contribution to journal › Article

Open Access

File

Clinical Decision Support Systems

Scotland

Medical problems

Decision support systems

Health care

4 Citations (Scopus)

26 Downloads (Pure)

DOLORisk: Study protocol for a multi-centre observational study to understand the risk factors and determinants of neuropathic pain [version 2; referees: 2 approved]

Pascal, M. M. V., Themistocleous, A. C., Baron, R., Binder, A., Bouhassira, D., Crombez, G., Finnerup, N. B., Gierthmühlen, J., Granovsky, Y., Groop, L., Hebert, H. L., Jensen, T. S., Johnsen, K., McCarthy, M. I., Meng, W., Palmer, C. N. A., Rice, A. S. C., Serra, J., Solà, R., Yarnitsky, D. & 3 others, Smith, B. H., Attal, N. & Bennett, D. L. H., 29 May 2018, In : Wellcome Open Research. 3, p. 1-23 23 p., 63.

Research output: Contribution to journal › Article

File

Neuralgia

Observational Studies

Network protocols

Ethics Committees

Neural Conduction

90 Downloads (Pure)

DOLORisk: study protocol for a multi-centre observational study to understand the risk factors and determinants of neuropathic pain

Pascal, M. M. V., Themistocleous, A. C., Baron, R., Binder, A., Bouhassira, D., Crombez, G., Finnerup, N. B., Gierthmühlen, J., Granovsky, Y., Groop, L., Hebert, H. L., Jensen, T. S., Johnsen, K., McCarthy, M. I., Meng, W., Palmer, C. N. A., Rice, A. S. C., Serra, J., Solà, R., Yarnitsky, D. & 3 others, Smith, B. H., Attal, N. & Bennett, D. L. H., 29 May 2018, In : Wellcome Open Research. 3, p. 1-16 16 p., 63.

Research output: Contribution to journal › Article

File

Neuralgia

Observational Studies

Network protocols

Ethics Committees

Chemotherapy

5 Citations (Scopus)

84 Downloads (Pure)

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., Li-Gao, R. & 93 others, Lin, H., Liu, C-T., Lyytikäinen, L-P., Marten, J., Mei, H., Müller-Nurasyid, M., Orini, M., Padmanabhan, S., Radmanesh, F., Ramirez, J., Robino, A., Schwartz, M., van Setten, J., Smith, A. V., Verweij, N., Warren, H. R., Weiss, S., Alonso, A., Arnar, D. O., Bots, M. L., de Boer, R. A., Dominiczak, A. F., Eijgelsheim, M., Ellinor, P. T., Guo, X., Felix, S. B., Harris, T. B., Hayward, C., Heckbert, S. R., Huang, P. L., Jukema, J. W., Kähönen, M., Kors, J. A., Lambiase, P. D., Launer, L. J., Li, M., Linneberg, A., Nelson, C. P., Pedersen, O., Perez, M., Peters, A., Polasek, O., Psaty, B. M., Raitakari, O. T., Rice, K., Rotter, J. I., Sinner, M. F., Soliman, E. Z., Spector, T. D., Strauch, K., Thorsteinsdottir, U., Tinker, A., Trompet, S., Uitterlinden, A. G., Vaartjes, I., van der Meer, P., Völker, U., Völzke, H., Waldenberger, M., Wilson, J. G., Xie, Z., Asselbergs, F. W., Dörr, M., van Duijn, C. M., Gasparini, P., Gudbjartsson, D. F., Gudnason, V., Hansen, T., Kääb, S., Kanters, J. K., Kooperberg, C., Lehtimäki, T., Lin, H. J., Lubitz, S. A., Mook-Kanamori, D. O., Conti, F. J., Newton-Cheh, C., Rosand, J., Rudan, I., Samani, N. J., Sinagra, G., Smith, B., Holm, H., Stricker, B. H. C., Ulivi, S., Sotoodehnia, N., Apte, S. S., van der Harst, P., Stefansson, K., Munroe, P. B., Arking, D. E., Lo, C. W. & Jamshidi, Y., 17 Jul 2018, In : Genome Biology. 19, p. 1-17 17 p., 87.

Research output: Contribution to journal › Article

Open Access

File

Exome

Connexin 43

Genome-Wide Association Study

Gap Junctions

Sudden Cardiac Death

188 Citations (Scopus)

223 Downloads (Pure)

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

23andMe Research Team, Lee, J. J., Wedow, R., Okbay, A., Kong, E., Maghzian, O., Zacher, M., Nguyen-Viet, T. A., Bowers, P., Sidorenko, J., Karlsson Linnér, R., Fontana, M. A., Kundu, T., Lee, C., Li, H., Li, R., Royer, R., Timshel, P. N., Walters, R. K., Willoughby, E. A. & 58 others, Yengo, L., Alver, M., Bao, Y., Clark, D. W., Day, F. R., Furlotte, N. A., Joshi, P. K., Kemper, K. E., Kleinman, A., Langenberg, C., Mägi, R., Trampush, J. W., Verma, S. S., Wu, Y., Lam, M., Zhao, J. H., Zheng, Z., Boardman, J. D., Campbell, H., Freese, J., Harris, K. M., Hayward, C., Herd, P., Kumari, M., Lencz, T., Luan, J., Malhotra, A. K., Metspalu, A., Milani, L., Ong, K. K., Smith, B. H., Perry, J. R. B., Porteous, D. J., Ritchie, M. D., Smart, M. C., Tung, J. Y., Wareham, N. J., Wilson, J. F., Beauchamp, J. P., Conley, D., Esko, T., Lehrer, S. F., Magnusson, P. K. E., Oskarsson, S., Pers, T. H., Robinson, M. R., Thom, K., Watson, C., Chabris, C. F., Meyer, M. N., Laibson, D., Yang, J., Johannesson, M., Koellinger, P. D., Turley, P., Visscher, P. M., Benjamin, D. J. & Cesarini, D., 23 Jul 2018, In : Nature Genetics. 50, 8, p. 1112-1121 10 p.

Research output: Contribution to journal › Article

Open Access

File

Genome-Wide Association Study

Genetic Association Studies

Single Nucleotide Polymorphism

Genome

Phenotype

5 Citations (Scopus)

124 Downloads (Pure)

Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Clarke, T-K., Zeng, Y., Navrady, L., Xia, C., Haley, C. S., Campbell, A., Navarro, P., Amador, C., Adams, M. J., Howard, D. M., Soler, A., Hayward, C., Thomson, P. A., Smith, B., Padmanabhan, S., Hocking, L. J., Hall, L. S., Porteous, D. J., Deary, I. J. & 1 others, McIntosh, A. M., 14 Feb 2018, In : Wellcome Open Research. 3, p. 1-10 10 p., 11.

Research output: Contribution to journal › Article

File

Major Depressive Disorder

Depression

Neuroticism

Genes

Family Health

1 Citation (Scopus)

89 Downloads (Pure)

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Arnau-Soler, A., Adams, M. J., Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Hayward, C. & Thomson, P. A., 20 Dec 2018, In : PLoS ONE. 13, 12, e0209160.

Research output: Contribution to journal › Article

Open Access

File

Major Depressive Disorder

Proxy

Genes

Genome

genome

10 Citations (Scopus)

90 Downloads (Pure)

Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain

Suri, P., Palmer, M. R., Tsepilov, Y. A., Freidin, M. B., Boer, C. G., Yau, M. S., Evans, D. S., Gelemanovic, A., Bartz, T. M., Nethander, M., Arbeeva, L., Karssen, L., Neogi, T., Campbell, A., Mellstrom, D., Ohlsson, C., Marshall, L. M., Orwoll, E., Uitterlinden, A., Rotter, J. I. & 17 others, Lauc, G., Psaty, B. M., Karlsson, M. K., Lane, N. E., Jarvik, G. P., Polasek, O., Hochberg, M., Jordan, J. M., Van Meurs, J. B. J., Jackson, R., Nielson, C. M., Mitchell, B. D., Smith, B. H., Hayward, C., Smith, N. L., Aulchenko, Y. S. & Williams, F. M. K., 27 Sep 2018, In : PLoS Genetics. 14, 9, p. 1-23 23 p., e1007601.

Research output: Contribution to journal › Article

Open Access

File

back (body region)

meta-analysis

Back Pain

ancestry

Chronic Pain

19 Citations (Scopus)

111 Downloads (Pure)

Incidence of iatrogenic opioid dependence or abuse in patients with pain who were exposed to opioid analgesic therapy: a systematic review and meta-analysis

Higgins, C., Smith, B. & Matthews, K., Jun 2018, In : British Journal of Anaesthesia. 120, 6, p. 1335-1344 10 p.

Research output: Contribution to journal › Review article

Open Access

File

Opioid Analgesics

Meta-Analysis

Pain

Incidence

Therapeutics

3 Citations (Scopus)

94 Downloads (Pure)

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Understanding Society Scientific Group, Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., Obeidat, M., Province, M. A., Gao, W., Qaiser, B., Porteous, D. J., Cassano, P. A., Ahluwalia, T. S., Grarup, N., Li, J., Altmaier, E., Marten, J., Harris, S. E., Manichaikul, A. & 33 others, Pottinger, T. D., Li-Gao, R., Lind-Thomsen, A., Mahajan, A., Lahousse, L., Imboden, M., Teumer, A., Prins, B., Lyytikäinen, L-P., Eiriksdottir, G., Franceschini, N., Sitlani, C. M., Brody, J. A., Bossé, Y., Timens, W., Kraja, A., Loukola, A., Tang, W., Liu, Y., Bork-Jensen, J., Justesen, J. M., Linneberg, A., Lange, L. A., Rawal, R., Karrasch, S., Huffman, J. E., Smith, B. H., Davies, G., Burkart, K. M., Mychaleckyj, J. C., Morris, A. P., Tobin, M. D. & London, S. J., 7 Aug 2018, In : Wellcome Open Research. 3, 28 p., 4.

Research output: Contribution to journal › Article

Open Access

File

Exome

Genetic Loci

Single Nucleotide Polymorphism

Meta-Analysis

Pulmonary diseases

47 Citations (Scopus)

212 Downloads (Pure)

Multi-ethnic genome-wide association study for atrial fibrillation

Roselli, C., Chaffin, M. D., Weng, L-C., Aeschbacher, S., Ahlberg, G., Albert, C. M., Almgren, P., Alonso, A., Anderson, C. D., Aragam, K. G., Arking, D. E., Barnard, J., Bartz, T. M., Benjamin, E. J., Bihlmeyer, N. A., Bis, J. C., Bloom, H. L., Boerwinkle, E., Bottinger, E. B., Brody, J. A. & 197 others, Calkins, H., Campbell, A., Cappola, T. P., Carlquist, J., Chasman, D. I., Chen, L. Y., Chen, Y-D. I., Choi, E-K., Choi, S. H., Christophersen, I. E., Chung, M. K., Cole, J. W., Conen, D., Cook, J., Crijns, H. J., Cutler, M. J., Damrauer, S. M., Daniels, B. R., Darbar, D., Delgado, G., Denny, J. C., Dichgans, M., Dörr, M., Dudink, E. A., Dudley, S. C., Esa, N., Esko, T., Eskola, M., Fatkin, D., Felix, S. B., Ford, I., Franco, O. H., Geelhoed, B., Grewal, R. P., Gudnason, V., Guo, X., Gupta, N., Gustafsson, S., Gutmann, R., Hamsten, A., Harris, T. B., Hayward, C., Heckbert, S. R., Hernesniemi, J., Hocking, L. J., Hofman, A., Horimoto, A. R. V. R., Huang, J., Huang, P. L., Huffman, J., Ingelsson, E., Ipek, E. G., Ito, K., Jimenez-Conde, J., Jukema, J. W., Kääb, S., Kähönen, M., Kamatani, Y., Kane, J. P., Kastrati, A., Kathiresan, S., Katschnig-Winter, P., Kavousi, M., Kessler, T., Kietselaer, B. L., Kirchhof, P., Kleber, M. E., Knight, S., Krieger, J. E., Kubo, M., Launer, L. J., Laurikka, J., Lehtimäki, T., Leineweber, K., Lemaitre, R. N., Li, M., Lim, H. E., Lin, H. J., Lin, H., Lind, L., Lindgren, C. M., Lokki, M-L., London, B., Loos, R. J. F., Low, S-K., Lu, Y., Lyytikäinen, L-P., Macfarlane, P. W., Magnusson, P. K., Mahajan, A., Malik, R., Mansur, A. J., Marcus, G. M., Margolin, L., Margulies, K. B., März, W., McManus, D. D., Melander, O., Mohanty, S., Montgomery, J. A., Morley, M. P., Morris, A. P., Müller-Nurasyid, M., Natale, A., Nazarian, S., Neumann, B., Newton-Cheh, C., Niemeijer, M. N., Nikus, K., Nilsson, P., Noordam, R., Oellers, H., Olesen, M. S., Orho-Melander, M., Padmanabhan, S., Pak, H-N., Paré, G., Pedersen, N. L., Pera, J., Pereira, A., Porteous, D., Psaty, B. M., Pulit, S. L., Pullinger, C. R., Rader, D. J., Refsgaard, L., Ribasés, M., Ridker, P. M., Rienstra, M., Risch, L., Roden, D. M., Rosand, J., Rosenberg, M. A., Rost, N., Rotter, J. I., Saba, S., Sandhu, R. K., Schnabel, R. B., Schramm, K., Schunkert, H., Schurman, C., Scott, S. A., Seppälä, I., Shaffer, C., Shah, S., Shalaby, A. A., Shim, J., Shoemaker, M. B., Siland, J. E., Sinisalo, J., Sinner, M. F., Slowik, A., Smith, A. V., Smith, B. H., Smith, J. G., Smith, J. D., Smith, N. L., Soliman, E. Z., Sotoodehnia, N., Stricker, B. H., Sun, A., Sun, H., Svendsen, J. H., Tanaka, T., Tanriverdi, K., Taylor, K. D., Teder-Laving, M., Teumer, A., Thériault, S., Trompet, S., Tucker, N. R., Tveit, A., Uitterlinden, A. G., van der Harst, P., Van Gelder, I. C., Van Wagoner, D. R., Verweij, N., Vlachopoulou, E., Völker, U., Wang, B., Weeke, P. E., Weijs, B., Weiss, R., Weiss, S., Wells, Q. S., Wiggins, K. L., Wong, J. A., Woo, D., Worrall, B. B., Yang, P-S., Yao, J., Yoneda, Z. T., Zeller, T., Zeng, L., Lubitz, S. A., Lunetta, K. L. & Ellinor, P. T., 11 Jun 2018, In : Nature Genetics. 50, 9, p. 1225-1233 15 p.

Research output: Contribution to journal › Article

Open Access

File

Genome-Wide Association Study

Atrial Fibrillation

Meta-Analysis

Genes

RNA Sequence Analysis

12 Citations (Scopus)

49 Downloads (Pure)

Neuropathic pain clinical trials: factors associated with decreases in estimated drug efficacy

Finnerup, N. B., Haroutounian, S., Baron, R., Dworkin, R. H., Gilron, I., Haanpaa, M. L., Jensen, T. S., Kamerman, P. R., McNicol, E., Moore, A., Raja, S. N., Andersen, N. T., Sena, E., Smith, B., Rice, A. S. C. & Attal, N., 1 Nov 2018, In : Pain. 159, 11, p. 2339-2346 8 p.

Research output: Contribution to journal › Article

Open Access

File

Neuralgia

Clinical Trials

Pain

Numbers Needed To Treat

Pharmaceutical Preparations

58 Citations (Scopus)

190 Downloads (Pure)

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P. & 31 others, Flannick, J., Grarup, N., Trubetskoy, V. V., Kravic, J., Kim, Y. J., Rybin, D. V., Yaghootkar, H., Müller-Nurasyid, M., Meidtner, K., Li-Gao, R., Varga, T. V., Marten, J., Li, J., Smith, A. V., An, P., Ligthart, S., Gustafsson, S., Malerba, G., Demirkan, A., Tajes, J. F., Steinthorsdottir, V., Wuttke, M., Lecoeur, C., Preuss, M., Bielak, L. F., Graff, M., Highland, H. M., Morris, A. D., Smith, B. H., Palmer, C. N. A. & ExomeBP Consortium, 9 Apr 2018, In : Nature Genetics. 50, 4, p. 559-571 13 p.

Research output: Contribution to journal › Article

Open Access

File

Type 2 Diabetes Mellitus

Causality

Odds Ratio

Genome

Therapeutics

1 Citation (Scopus)

49 Downloads (Pure)

Substance misuse in patients who have comorbid chronic pain in a clinical population receiving methadone maintenance therapy for the treatment of opioid dependence

Higgins, C., Smith, B. & Matthews, K., 1 Dec 2018, In : Drug and Alcohol Dependence. 193, p. 131-136 6 p.

Research output: Contribution to journal › Article

Open Access

File

Cannabinoids

Methadone

Benzodiazepines

Chronic Pain

Opioid Analgesics

11 Citations (Scopus)

176 Downloads (Pure)

Systematic review and meta-analysis of genetic risk factors for neuropathic pain

Veluchamy, A., Hébert, H. L., Meng, W., Palmer, C. N. A. & Smith, B. H., May 2018, In : Pain. 159, 5, p. 825-848 24 p.

Research output: Contribution to journal › Review article

Open Access

File

Neuralgia

Meta-Analysis

HLA-A Antigens

Genes

HLA-DRB1 Chains

Smith, Blair, MD MEd FRCGP FFPMRCA FRCP Edin