• 6249 Citations
  • 38 h-Index
1993 …2022
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Personal profile


I am Professor of Primary Care Medicine at the University of Dundee Medical School where I carry out applied research to translate basic and clinical research into effective and reliable clinical practice. I am additionally an Honorary Consultant in NHS Fife and a General Practitioner in Cardenden in Fife. I was previously a Medical Research Council Health Services Research Fellow at University of Edinburgh, an National Institute for Health Research post-doctoral research fellow at University of Dundee, and a 2006/7 Commonwealth Fund Harkness Fellow in Healthcare Policy at University of California San Francisco where I was also a Visiting Professor in 2010. I regularly review for various grant-making bodies and journals, contribute to undergraduate and postgraduate medical teaching, and supervise and examine MSc and PhD students in Dundee and other universities. As well as conducting research, I serve or have served on a number of National Health Service advisory bodies, including the National Institute for Health and Clinical Excellence (NICE) Quality and Outcomes Framework Indicators Advisory Committee (which recommended which quality indicators should be included in the UK primary care pay for performance programme) where I chaired the Thresholds, Review and Retiral Sub-committee, and the Scottish Government Polypharmacy Working Group. I was the chair of the guideline development group of the NICE Multimorbidity Clinical Guideline published in late 2016. 


My main research interests are the quality and safety of healthcare, particularly in primary care and currently focused on prescribing quality and safety, multimorbidity the organisation of healthcare. I am a mixed methods researcher and collaborate with researchers from a wide range of disciplines and institutions. The methods I use include quantitative analysis of large, routine datasets; cluster randomised trials with mixed methods parallel process evaluations; and qualitative analysis of interview and observational data. My recent and current work includes development and evaluation of interventions to improve polypharmacy, examination of the implications of competing mortality risk for single disease risk prediction, and examination of the applicability of trial evidence to clinical populations. 

Education/Academic qualification

Doctor of Philosophy, University of Edinburgh

Master of Science, University of Edinburgh

Bachelor of Medicine and Bachelor of Surgery, University of Cambridge

Bachelor of Arts, University of Cambridge


  • R Medicine (General)
  • Primary Care Medicine
  • Prescribing Quality and Safety
  • Mixed quantitative and qualitative methods
  • Community based trials
  • Quality of healthcare
  • Organisation of healthcare

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 96 Similar Profiles
Primary Health Care Medicine & Life Sciences
Comorbidity Medicine & Life Sciences
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General Practice Medicine & Life Sciences
Cross-Sectional Studies Medicine & Life Sciences
Population Medicine & Life Sciences
Quality Improvement Medicine & Life Sciences
Safety Medicine & Life Sciences

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Projects 2012 2022

Research Output 1993 2019

45 Citations

Safer Prescribing: A Trial of Education, Informatics, and Financial Incentives

Dreischulte, T., Donnan, P., Grant, A., Hapca, A., McCowan, C. & Guthrie, B., 17 Mar 2016, In : New England Journal of Medicine. 374, 11, p. 1053-1064 12 p.

Research output: Contribution to journalArticle

Open Access
Drug Prescriptions
Primary Health Care
1747 Citations

Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study

Barnett, K., Mercer, S. W., Norbury, M., Watt, G., Wyke, S. & Guthrie, B., 2012, In : Lancet. 380, 9836, p. 37-43 7 p.

Research output: Contribution to journalArticle

Health Services Research
Medical Education
Cross-Sectional Studies
13 Citations

Data feedback and behavioural change intervention to improve primary care prescribing safety (EFIPPS): multicentre, three arm, cluster randomised controlled trial

Guthrie, B., Kavanagh, K., Robertson, C., Barnett, K., Treweek, S., Petrie, D., Ritchie, L. D. & Bennie, M., 18 Aug 2016, In : BMJ. 354, p. 1-9 9 p., i4079.

Research output: Contribution to journalArticle

Open Access
Primary Health Care
Randomized Controlled Trials
Intention to Treat Analysis
Electronic Health Records
80 Citations

Drug-disease and drug-drug interactions: systematic examination of recommendations in 12 UK national clinical guidelines

Dumbreck, S., Flynn, A., Nairn, M., Wilson, M., Treweek, S., Mercer, S. W., Alderson, P., Thompson, A., Payne, K. & Guthrie, B., 11 Mar 2015, In : BMJ. 350, 8 p., h949.

Research output: Contribution to journalArticle

Open Access
Drug Interactions
Pharmaceutical Preparations
Type 2 Diabetes Mellitus
National Institutes of Health (U.S.)
15 Citations
Open Access
General Hospitals
Cohort Studies

Press / Media

Better guidelines needed for multimorbidity

Bruce Guthrie & Marion McMurdo


1 item of media coverage

Press/Media: Research

Study calls for reviews of psychotropic medication

Colin McCowan, Bruce Guthrie & Stella Clark


1 item of media coverage

Press/Media: Research

New research on multiple medical conditions

Karen Barnett, Bruce Guthrie & Michael Norbury


1 item of media coverage

Press/Media: Research

60,000 Scots prescribed 'high risk' drugs

Bruce Guthrie


1 item of media coverage

Press/Media: Research


Quantifying the Risk of Beta-Blockers and Non-Steroidal Anti-Inflammatory Drugs in Asthma

Author: Morales, D., 2014

Supervisor: Guthrie, B. (Supervisor), Donnan, P. (Supervisor) & Jackson, C. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy


The impact and use of patient feedback in general practice: A realist review

Author: Baldie, D., 2014

Supervisor: Guthrie, B. (Supervisor), Kroll, T. (Supervisor), Entwistle, V. A. (External person) (Supervisor) & Williams, B. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy