Fraser, Callum

Dr

  • 2355 Citations
  • 25 h-Index
1991 …2021

Research output per year

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Research Output

2019

A dynamic reference change value model applied to ongoing assessment of the steady state of a biomarker using more than two serial results

Lund, F., Hyltoft Petersen, P. & Fraser, C. G., Mar 2019, In : Annals of Clinical Biochemistry. 56, 2, p. 283-294 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
Open Access
File
35 Downloads (Pure)

Changes in prevalence of faecal occult blood positivity over time

Goulding, A., Clark, G. R. C., Anderson, A. S., Strachan, J. A., Fraser, C. G. & Steele, R. J. C., Dec 2019, In : Journal of Medical Screening. 26, 4, p. 191-196 6 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
61 Downloads (Pure)

Do other variables add value to assessment of the risk of colorectal disease using faecal immunochemical tests for haemoglobin?

Digby, J., Steele, B., Strachan, J. A., Mowat, C., Anderson, A., McCann, R., Law, L. & Fraser, C., 1 Jul 2019, In : Annals of Clinical Biochemistry. 56, 4, p. 472-479 8 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
36 Downloads (Pure)

Pruebas inmunoquímicas fecales (PIF) para determinar la hemoglobina en la evaluación de pacientes con síntomas abdominales inferiores: controversias actuales

Translated title of the contribution: Faecal immunochemical tests for haemoglobin (FIT) in the assessment of patients with lower abdominal symptoms: current controversiesFraser, C. G., Apr 2019, In : Gastroenterologia y Hepatologia. 42, 4, p. 263-270 8 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
35 Downloads (Pure)

Randomized controlled trial: Flexible sigmoidoscopy as an adjunct to faecal occult blood testing in population screening

Steele, R. J. C., Carey, F. A., Stanners, G., Lang, J., Brand, J., Brownlee, L. A., Crichton, E. M., Winter, J. W., Phull, P. S., Mowat, C., Strachan, J. A., Digan, A-M. & Fraser, C. G., 5 Nov 2019, In : Journal of Medical Screening.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
174 Downloads (Pure)
2018

A comparative effectiveness trial of two faecal immunochemical tests for haemoglobin (FIT). Assessment of test performance and adherence in a single round of a population-based screening programme for colorectal cancer

Passamonti, B., Malaspina, M., Fraser, C. G., Tintori, B., Carlani, A., D'Angelo, V., Galeazzi, P., Di Dato, E., Mariotti, L., Bulletti, S., D'Amico, M. R., Gustinucci, D., Martinelli, N., Spita, N., Cesarini, E., Rubeca, T., Giaimo, M., Segnan, N. & Senore, C., Mar 2018, In : Gut. 67, 3, p. 485-496 12 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
180 Downloads (Pure)

Application of NICE guideline NG12 to the initial assessment of patients with lower gastrointestinal symptoms: not FIT for purpose?

Quyn, A. J., Steele, R. J. C., Digby, J., Strachan, J. A., Mowat, C., McDonald, P. J., Carey, F. A., Godber, I. M., Ben Younes, H. & Fraser, C. G., 1 Jan 2018, In : Annals of Clinical Biochemistry. 55, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
197 Downloads (Pure)
1 Citation (Scopus)
147 Downloads (Pure)
Open Access
File
5 Citations (Scopus)
80 Downloads (Pure)

Faecal immunochemical tests (FIT) in the assessment of patients presenting with lower bowel symptoms: Concepts and challenges

Fraser, C. G., 1 Oct 2018, In : Surgeon. 16, 5, p. 302-308 7 p.

Research output: Contribution to journalReview article

Open Access
File
13 Citations (Scopus)
59 Downloads (Pure)

Gender-partitioned patient medians of serum albumin requested by general practitioners for the assessment of analytical stability

Hansen, S. I., Petersen, P. H., Lund, F., Fraser, C. G. & Sölétormos, G., May 2018, In : Clinical Chemistry and Laboratory Medicine. 56, 5, p. 843-850 8 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
112 Downloads (Pure)

Occult blood in faeces is associated with all-cause and non-colorectal cancer mortality

Libby, G., Fraser, C., Carey, F., Brewster, D. H. & Steele, R., Dec 2018, In : Gut. 67, 12, p. 2116-2123 8 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
176 Downloads (Pure)

Participation in bowel screening among men attending abdominal aortic aneurysm screening

Quyn, A. J., Fraser, C. G., Rodger, J., Digan, A., Anderson, A. S. & Steele, R. J. C., 1 Apr 2018, In : British Journal of Surgery. 105, 5, p. 529-534 6 p.

Research output: Contribution to journalArticle

Open Access
File
57 Downloads (Pure)

Scottish Bowel Screening Programme colonoscopy quality – scope for improvement?

Quyn, A., Fraser, C., Stanners, G., Carey, F., Rees, C. J., Moores, B. & Steele, R., Sep 2018, In : Colorectal Disease. 20, 9, p. O277-O283 7 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
141 Downloads (Pure)

Setting up a service for a faecal immunochemical test for haemoglobin (FIT): a review of considerations, challenges and constraints

Godber, I. M., Benton, S. C. & Fraser, C. G., Dec 2018, In : Journal of Clinical Pathology. 71, 12, p. 1041-1045 5 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Uptake trends in the Scottish Bowel Screening Programme and the influences of age, sex and deprivation

Quyn, A. J., Fraser, C. G., Stanners, G., Carey, F. A., Carden, C., Shaukat, A. & Steele, R. J. C., 1 Mar 2018, In : Journal of Medical Screening. 25, 1, p. 24-31 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Valid analytical performance specifications for combined analytical bias and imprecision for the use of common reference intervals

Hyltoft Petersen, P., Lund, F., Fraser, C. G., Sandberg, S. & Sölétormos, G., 1 Sep 2018, In : Annals of Clinical Biochemistry. 55, 5, p. 612-615 4 p.

Research output: Contribution to journalArticle

2017

Calculation of reference change values using more than two results is a difficult task

Lund, F., Petersen, P. H., Fraser, C. G. & Sölétormos, G., 1 May 2017, In : Annals of Clinical Biochemistry. 54, 3, p. 412-413 2 p.

Research output: Contribution to journalLetter

2 Citations (Scopus)
Open Access
File
141 Downloads (Pure)

Faecal haemoglobin concentration is related to detection of advanced colorectal neoplasia in the next screening round

Digby, J., Fraser, C. G., Carey, F. A., Diament, R. H., Balsitis, M. & Steele, R. J. C., Jun 2017, In : Journal of Medical Screening. 24, 2, p. 62-68 7 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
173 Downloads (Pure)

Faecal immunochemical tests (FIT) can help to rule out colorectal cancer in patients presenting in primary care with lower abdominal symptoms: a systematic review conducted to inform new NICE DG30 diagnostic guidance

Westwood, M., Lang, S., Armstrong, N., van Turenhout, S., Cubiella, J., Stirk, L., Corro Ramos, I., Luyendijk, M., Zaim, R., Kleijnen, J. & Fraser, C. G., 24 Oct 2017, In : BMC Medicine. 15, p. 1-17 17 p., 189.

Research output: Contribution to journalReview article

Open Access
File
24 Citations (Scopus)
168 Downloads (Pure)

Faecal immunochemical tests (FIT) for haemoglobin for timely assessment of patients with symptoms of colorectal disease

Steele, R. J. C. & Fraser, C. G., 8 Nov 2017, Timely Diagnosis of Colorectal Cancer. Olsson, L. (ed.). Switzerland: Springer International Publishing, p. 39-66 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Population-based colorectal cancer screening programmes using a faecal immunochemical test: Should faecal haemoglobin cut-offs differ by age and sex?

Arana-Arri, E., Idigoras, I., Uranga, B., Pérez, R., Irurzun, A., Gutiérrez-Ibarluzea, I., Fraser, C. G., Portillo, I., Luis Hurtado, J., de No, C., Enciso, C., Escalante, M., Atarés, B., Aguirre, J. J., Pereda, E., Marañón, E., Otazua, P., Fernández-Ávila, M. J., Egido, J. F., Zapata, E. & 31 others, Zubiaurre, L., Rodríguez, J. M., Sampedro, P. E., Goyeneche, M., Arrinda, J. M., Jauregui, M. L., Gómez, M., Saiz, M., Bujanda, L., Gil, I., Montalvo, I., Larzabal, J. M., Garmendia, M., Izquierdo, F., Fernández, F. J., Rodríguez, I., Huerta, A., de Miguel, E., Barredo, I., Bao, F., Hernández, A., Rodriguez, I., Fernández-Landa, M. J., Imaz, M., Calderón, A., Polo, F., Arbide, N., Lantarón, G., Quesada, C., Marzana, I. & EUSKOLON Group, 29 Aug 2017, In : BMC Cancer. 17, 1, p. 1-13 13 p., 577.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
119 Downloads (Pure)

Separate patient serum sodium medians from males and females provide independent information on analytical bias

Hansen, S. I., Petersen, P. H., Lund, F., Fraser, C. G. & Sölétormos, G., 26 Oct 2017, In : Clinical Chemistry and Laboratory Medicine. 55, 12

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
138 Downloads (Pure)

The FAST (Faecal Haemoglobin Concentration, Age and Sex Test) Score: development and external validation of a simple prediction tool for colorectal cancer detection in symptomatic patients

on behalf of the COLONPREDICT study investigators, 15 May 2017, In : International Journal of Cancer. 140, 10, p. 2201-2211 11 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
78 Downloads (Pure)
2016

Analytical performance specifications for changes in assay bias (Δbias) for data with logarithmic distributions as assessed by effects on reference change values

Petersen, P. H., Lund, F., Fraser, C. G. & Sölétormos, G., 1 Nov 2016, In : Annals of Clinical Biochemistry. 53, 6, p. 686-691 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A nicer approach to the use of 'faecal occult blood tests' in assessment of the symptomatic

Fraser, C. G. & Strachan, J. A., Jan 2016, In : Annals of Clinical Biochemistry. 53, 1, p. 5-6 2 p.

Research output: Contribution to journalEditorial

7 Citations (Scopus)

Clinical utility of one versus two faecal immunochemical test samples in the detection of advanced colorectal neoplasia in symptomatic patients

Auge, J. M., Fraser, C. G., Rodriguez, C., Roset, A., Lopez-Ceron, M., Grau, J., Castells, A. & Jimenez, W., Jan 2016, In : Clinical Chemistry and Laboratory Medicine. 54, 1, p. 125-132 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Comparison of quantitative faecal immunochemical tests for haemoglobin (FIT) for asymptomatic population screening

Fraser, C. G., Oct 2016, In : Translational Cancer Research. 5, Suppl. 4, p. S916-S919 4 p.

Research output: Contribution to journalComment/debate

Open Access
File
3 Citations (Scopus)
108 Downloads (Pure)
Open Access
File
6 Citations (Scopus)
108 Downloads (Pure)
5 Citations (Scopus)
139 Downloads (Pure)

Interval cancers in a national colorectal cancer screening programme

Steele, R. J. C., Stanners, G., Lang, J., Brewster, D. H., Carey, F. A. & Fraser, C. G., Aug 2016, In : United European Gastroenterology Journal. 4, 4, p. 587-594 8 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
113 Downloads (Pure)

Interval cancers using a quantitative faecal immunochemical test (FIT) for haemoglobin when colonoscopy capacity is limited

Digby, J., Fraser, C. G., Carey, F. A., Lang, J., Stanners, G. & Steele, R. J. C., 8 Aug 2016, In : Journal of Medical Screening. 23, 3, p. 130-134 5 p.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
168 Downloads (Pure)

Re: A proposal to standardize reporting units for fecal immunochemical tests for hemoglobin

Fraser, C. G., Rapi, S. & Rubeca, T., Jan 2016, In : Journal of the National Cancer Institute. 108, 1, 2 p., djv312.

Research output: Contribution to journalLetter

5 Citations (Scopus)
2015

Advances in fecal occult blood tests: The FIT revolution

Young, G. P., Symonds, E. L., Allison, J. E., Cole, S. R., Fraser, C. G., Halloran, S. P., Kuipers, E. J. & Seaman, H. E., Mar 2015, In : Digestive Diseases and Sciences. 60, 3, p. 609-622 14 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Biological variation: a still evolving facet of laboratory medicine

Simundic, A. M., Bartlett, W. A. & Fraser, C. G., Mar 2015, In : Annals of Clinical Biochemistry. 52, 2, p. 189-190 2 p.

Research output: Contribution to journalEditorial

10 Citations (Scopus)

Calculation of limits for significant bidirectional changes in two or more serial results of a biomarker based on a computer simulation model

Lund, F., Petersen, P. H., Fraser, C. G. & Sölétormos, G., Jul 2015, In : Annals of Clinical Biochemistry. 52, 4, p. 434-440 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Calculation of limits for significant unidirectional changes in two or more serial results of a biomarker based on a computer simulation model

Lund, F., Petersen, P. H., Fraser, C. G. & Sölétormos, G., Mar 2015, In : Annals of Clinical Biochemistry. 52, 2, p. 237-244 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Confirmation of analytical performance characteristics required for the reference change value applied in patient monitoring

Petersen, P. H., Fraser, C. G., Lund, F. & Sölétormos, G., 2015, In : Scandinavian Journal of Clinical & Laboratory Investigation. 75, 7, p. 628-630 3 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)

Defining analytical performance specifications: consensus statement from the 1st Strategic Conference of the European Federation of Clinical Chemistry and Laboratory Medicine

Sandberg, S., Fraser, C. G., Horvath, A. R., Jansen, R., Jones, G., Oosterhuis, W., Petersen, P. H., Schimmel, H., Sikaris, K. & Panteghini, M., May 2015, In : Clinical Chemistry and Laboratory Medicine. 53, 6, p. 833-835 3 p.

Research output: Contribution to journalArticle

215 Citations (Scopus)

Faecal haemoglobin and faecal calprotectin as indicators of bowel disease in patients presenting to primary care with bowel symptoms

Mowat, C., Digby, J., Strachan, J. A., Wilson, R., Carey, F. A., Fraser, C. G. & Steele, R. J. C., Sep 2015, In : Gut. 65, 9, p. 1463-1469 8 p.

Research output: Contribution to journalArticle

Open Access
File
56 Citations (Scopus)
1158 Downloads (Pure)

Faecal haemoglobin concentrations do vary across geography as well as with age and sex: ramifications for colorectal cancer screening

Fraser, C. G., Auge, J. M. & on behalf of the PROCOLON Group, Aug 2015, In : Clinical Chemistry and Laboratory Medicine. 53, 9, p. e235-e237 3 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)
11 Citations (Scopus)

Impact of preanalytical factors on fecal immunochemical tests: need for new strategies in comparison of methods

Rubeca, T., Cellai, F., Confortini, M., Fraser, C. G. & Rapi, S., 2015, In : International Journal of Biological Markers. 30, 3, p. e269-e274 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Terms and symbols used in studies on biological variation: the need for harmonization

Simundic, A. M., Kackov, S., Miler, M., Fraser, C. G. & Petersen, P. H., Feb 2015, In : Clinical Chemistry. 61, 2, p. 438-439 2 p.

Research output: Contribution to journalLetter

20 Citations (Scopus)