Fraser, Callum

Dr

  • 2362 Citations
  • 25 h-Index
1991 …2021

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2019

A dynamic reference change value model applied to ongoing assessment of the steady state of a biomarker using more than two serial results

Lund, F., Hyltoft Petersen, P. & Fraser, C. G., Mar 2019, In : Annals of Clinical Biochemistry. 56, 2, p. 283-294 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
Open Access
File
36 Downloads (Pure)

Changes in prevalence of faecal occult blood positivity over time

Goulding, A., Clark, G. R. C., Anderson, A. S., Strachan, J. A., Fraser, C. G. & Steele, R. J. C., Dec 2019, In : Journal of Medical Screening. 26, 4, p. 191-196 6 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
64 Downloads (Pure)

Do other variables add value to assessment of the risk of colorectal disease using faecal immunochemical tests for haemoglobin?

Digby, J., Steele, B., Strachan, J. A., Mowat, C., Anderson, A., McCann, R., Law, L. & Fraser, C., 1 Jul 2019, In : Annals of Clinical Biochemistry. 56, 4, p. 472-479 8 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
36 Downloads (Pure)

Pruebas inmunoquímicas fecales (PIF) para determinar la hemoglobina en la evaluación de pacientes con síntomas abdominales inferiores: controversias actuales

Translated title of the contribution: Faecal immunochemical tests for haemoglobin (FIT) in the assessment of patients with lower abdominal symptoms: current controversiesFraser, C. G., Apr 2019, In : Gastroenterologia y Hepatologia. 42, 4, p. 263-270 8 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
43 Downloads (Pure)

Randomized controlled trial: Flexible sigmoidoscopy as an adjunct to faecal occult blood testing in population screening

Steele, R. J. C., Carey, F. A., Stanners, G., Lang, J., Brand, J., Brownlee, L. A., Crichton, E. M., Winter, J. W., Phull, P. S., Mowat, C., Strachan, J. A., Digan, A-M. & Fraser, C. G., 5 Nov 2019, In : Journal of Medical Screening.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
175 Downloads (Pure)
2018

A comparative effectiveness trial of two faecal immunochemical tests for haemoglobin (FIT). Assessment of test performance and adherence in a single round of a population-based screening programme for colorectal cancer

Passamonti, B., Malaspina, M., Fraser, C. G., Tintori, B., Carlani, A., D'Angelo, V., Galeazzi, P., Di Dato, E., Mariotti, L., Bulletti, S., D'Amico, M. R., Gustinucci, D., Martinelli, N., Spita, N., Cesarini, E., Rubeca, T., Giaimo, M., Segnan, N. & Senore, C., Mar 2018, In : Gut. 67, 3, p. 485-496 12 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
183 Downloads (Pure)

Application of NICE guideline NG12 to the initial assessment of patients with lower gastrointestinal symptoms: not FIT for purpose?

Quyn, A. J., Steele, R. J. C., Digby, J., Strachan, J. A., Mowat, C., McDonald, P. J., Carey, F. A., Godber, I. M., Ben Younes, H. & Fraser, C. G., 1 Jan 2018, In : Annals of Clinical Biochemistry. 55, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
202 Downloads (Pure)
Open Access
File
6 Citations (Scopus)
85 Downloads (Pure)

Gender-partitioned patient medians of serum albumin requested by general practitioners for the assessment of analytical stability

Hansen, S. I., Petersen, P. H., Lund, F., Fraser, C. G. & Sölétormos, G., May 2018, In : Clinical Chemistry and Laboratory Medicine. 56, 5, p. 843-850 8 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
116 Downloads (Pure)

Occult blood in faeces is associated with all-cause and non-colorectal cancer mortality

Libby, G., Fraser, C., Carey, F., Brewster, D. H. & Steele, R., Dec 2018, In : Gut. 67, 12, p. 2116-2123 8 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
180 Downloads (Pure)

Participation in bowel screening among men attending abdominal aortic aneurysm screening

Quyn, A. J., Fraser, C. G., Rodger, J., Digan, A., Anderson, A. S. & Steele, R. J. C., 1 Apr 2018, In : British Journal of Surgery. 105, 5, p. 529-534 6 p.

Research output: Contribution to journalArticle

Open Access
File
59 Downloads (Pure)

Scottish Bowel Screening Programme colonoscopy quality – scope for improvement?

Quyn, A., Fraser, C., Stanners, G., Carey, F., Rees, C. J., Moores, B. & Steele, R., Sep 2018, In : Colorectal Disease. 20, 9, p. O277-O283 7 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
143 Downloads (Pure)

Setting up a service for a faecal immunochemical test for haemoglobin (FIT): a review of considerations, challenges and constraints

Godber, I. M., Benton, S. C. & Fraser, C. G., Dec 2018, In : Journal of Clinical Pathology. 71, 12, p. 1041-1045 5 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Uptake trends in the Scottish Bowel Screening Programme and the influences of age, sex and deprivation

Quyn, A. J., Fraser, C. G., Stanners, G., Carey, F. A., Carden, C., Shaukat, A. & Steele, R. J. C., 1 Mar 2018, In : Journal of Medical Screening. 25, 1, p. 24-31 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Valid analytical performance specifications for combined analytical bias and imprecision for the use of common reference intervals

Hyltoft Petersen, P., Lund, F., Fraser, C. G., Sandberg, S. & Sölétormos, G., 1 Sep 2018, In : Annals of Clinical Biochemistry. 55, 5, p. 612-615 4 p.

Research output: Contribution to journalArticle

2017

Faecal haemoglobin concentration is related to detection of advanced colorectal neoplasia in the next screening round

Digby, J., Fraser, C. G., Carey, F. A., Diament, R. H., Balsitis, M. & Steele, R. J. C., Jun 2017, In : Journal of Medical Screening. 24, 2, p. 62-68 7 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
177 Downloads (Pure)

Population-based colorectal cancer screening programmes using a faecal immunochemical test: Should faecal haemoglobin cut-offs differ by age and sex?

Arana-Arri, E., Idigoras, I., Uranga, B., Pérez, R., Irurzun, A., Gutiérrez-Ibarluzea, I., Fraser, C. G., Portillo, I., Luis Hurtado, J., de No, C., Enciso, C., Escalante, M., Atarés, B., Aguirre, J. J., Pereda, E., Marañón, E., Otazua, P., Fernández-Ávila, M. J., Egido, J. F., Zapata, E. & 31 others, Zubiaurre, L., Rodríguez, J. M., Sampedro, P. E., Goyeneche, M., Arrinda, J. M., Jauregui, M. L., Gómez, M., Saiz, M., Bujanda, L., Gil, I., Montalvo, I., Larzabal, J. M., Garmendia, M., Izquierdo, F., Fernández, F. J., Rodríguez, I., Huerta, A., de Miguel, E., Barredo, I., Bao, F., Hernández, A., Rodriguez, I., Fernández-Landa, M. J., Imaz, M., Calderón, A., Polo, F., Arbide, N., Lantarón, G., Quesada, C., Marzana, I. & EUSKOLON Group, 29 Aug 2017, In : BMC Cancer. 17, 1, p. 1-13 13 p., 577.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
121 Downloads (Pure)

Separate patient serum sodium medians from males and females provide independent information on analytical bias

Hansen, S. I., Petersen, P. H., Lund, F., Fraser, C. G. & Sölétormos, G., 26 Oct 2017, In : Clinical Chemistry and Laboratory Medicine. 55, 12

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
144 Downloads (Pure)

The FAST (Faecal Haemoglobin Concentration, Age and Sex Test) Score: development and external validation of a simple prediction tool for colorectal cancer detection in symptomatic patients

on behalf of the COLONPREDICT study investigators, 15 May 2017, In : International Journal of Cancer. 140, 10, p. 2201-2211 11 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
78 Downloads (Pure)
2016

Analytical performance specifications for changes in assay bias (Δbias) for data with logarithmic distributions as assessed by effects on reference change values

Petersen, P. H., Lund, F., Fraser, C. G. & Sölétormos, G., 1 Nov 2016, In : Annals of Clinical Biochemistry. 53, 6, p. 686-691 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Clinical utility of one versus two faecal immunochemical test samples in the detection of advanced colorectal neoplasia in symptomatic patients

Auge, J. M., Fraser, C. G., Rodriguez, C., Roset, A., Lopez-Ceron, M., Grau, J., Castells, A. & Jimenez, W., Jan 2016, In : Clinical Chemistry and Laboratory Medicine. 54, 1, p. 125-132 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
5 Citations (Scopus)
142 Downloads (Pure)

Interval cancers in a national colorectal cancer screening programme

Steele, R. J. C., Stanners, G., Lang, J., Brewster, D. H., Carey, F. A. & Fraser, C. G., Aug 2016, In : United European Gastroenterology Journal. 4, 4, p. 587-594 8 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
116 Downloads (Pure)

Interval cancers using a quantitative faecal immunochemical test (FIT) for haemoglobin when colonoscopy capacity is limited

Digby, J., Fraser, C. G., Carey, F. A., Lang, J., Stanners, G. & Steele, R. J. C., 8 Aug 2016, In : Journal of Medical Screening. 23, 3, p. 130-134 5 p.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
169 Downloads (Pure)
2015

Advances in fecal occult blood tests: The FIT revolution

Young, G. P., Symonds, E. L., Allison, J. E., Cole, S. R., Fraser, C. G., Halloran, S. P., Kuipers, E. J. & Seaman, H. E., Mar 2015, In : Digestive Diseases and Sciences. 60, 3, p. 609-622 14 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Calculation of limits for significant bidirectional changes in two or more serial results of a biomarker based on a computer simulation model

Lund, F., Petersen, P. H., Fraser, C. G. & Sölétormos, G., Jul 2015, In : Annals of Clinical Biochemistry. 52, 4, p. 434-440 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Calculation of limits for significant unidirectional changes in two or more serial results of a biomarker based on a computer simulation model

Lund, F., Petersen, P. H., Fraser, C. G. & Sölétormos, G., Mar 2015, In : Annals of Clinical Biochemistry. 52, 2, p. 237-244 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Defining analytical performance specifications: consensus statement from the 1st Strategic Conference of the European Federation of Clinical Chemistry and Laboratory Medicine

Sandberg, S., Fraser, C. G., Horvath, A. R., Jansen, R., Jones, G., Oosterhuis, W., Petersen, P. H., Schimmel, H., Sikaris, K. & Panteghini, M., May 2015, In : Clinical Chemistry and Laboratory Medicine. 53, 6, p. 833-835 3 p.

Research output: Contribution to journalArticle

215 Citations (Scopus)

Faecal haemoglobin and faecal calprotectin as indicators of bowel disease in patients presenting to primary care with bowel symptoms

Mowat, C., Digby, J., Strachan, J. A., Wilson, R., Carey, F. A., Fraser, C. G. & Steele, R. J. C., Sep 2015, In : Gut. 65, 9, p. 1463-1469 8 p.

Research output: Contribution to journalArticle

Open Access
File
57 Citations (Scopus)
1164 Downloads (Pure)
11 Citations (Scopus)

Impact of preanalytical factors on fecal immunochemical tests: need for new strategies in comparison of methods

Rubeca, T., Cellai, F., Confortini, M., Fraser, C. G. & Rapi, S., 2015, In : International Journal of Biological Markers. 30, 3, p. e269-e274 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
19 Citations (Scopus)
2014

Deprivation and faecal haemoglobin: implications for bowel cancer screening

Digby, J., McDonald, P. J., Strachan, J. A., Libby, G., Steele, R. J. C. & Fraser, C. G., Jun 2014, In : Journal of Medical Screening. 21, 2, p. 95-97 3 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Faecal haemoglobin concentrations vary with sex and age, but data are not transferable across geography for colorectal cancer screening

Fraser, C. G., Rubeca, T., Rapi, S., Chen, L-S. & Chen, H-H., Aug 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 8, p. 1211-6 6 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Patterns of uptake in a biennial faecal occult blood test screening programme for colorectal cancer

Steele, R. J. C., McClements, P. L., Libby, G., Carey, F. A. & Fraser, C. . G., Jan 2014, In : Colorectal Disease. 16, 1, p. 28-32 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Population screening for colorectal cancer means getting FIT: the past, present, and future of colorectal cancer screening using the fecal immunochemical test for hemoglobin (FIT)

Allison, J. E., Fraser, C. G., Halloran, S. P. & Young, G. P., Mar 2014, In : Gut and Liver. 8, 2, p. 117-130 14 p.

Research output: Contribution to journalArticle

Open Access
File
79 Citations (Scopus)
123 Downloads (Pure)
2013

Clinical outcomes using a faecal immunochemical test for haemoglobin as a first-line test in a national programme constrained by colonoscopy capacity

Steele, R. JC., McDonald, P. J., Digby, J., Brownlee, L., Strachan, J. A., Libby, G., McClements, P. L., Birrell, J., Carey, F. A., Diament, R. H., Balsitis, M. & Fraser, C. G., Jun 2013, In : United European Gastroenterology Journal. 1, 3, p. 198-205 8 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Faecal haemoglobin concentration is related to severity of colorectal neoplasia

Digby, J., Fraser, C. G., Carey, F. A., McDonald, P. J., Strachan, J. A., Diament, R. H., Balsitis, M. & Steele, R. J. C., 2013, In : Journal of Clinical Pathology. 66, 5, p. 415-419 5 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Low faecal haemoglobin concentration potentially rules out significant colorectal disease

McDonald, P. J., Digby, J., Innes, C., Strachan, J. A., Carey, F. A., Steele, R. J. C. & Fraser, C. G., Mar 2013, In : Colorectal Disease. 15, 3, p. e151-e159 9 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Making colorectal cancer screening FITTER for purpose with quantitative faecal immunochemical tests for haemoglobin (FIT)

Fraser, C. G., Halloran, S. P., Allison, J. E. & Young, G. P., Nov 2013, In : Clinical Chemistry and Laboratory Medicine. 51, 11, p. 2065-2067 3 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Quantitation of Hemoglobin Improves Fecal Immunochemical Tests for Noninvasive Screening

Fraser, C. G., Allison, J. E., Young, G. P. & Halloran, S. P., Jul 2013, In : Clinical Gastroenterology and Hepatology. 11, 7, p. 839-840 2 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Use of a faecal immunochemical test narrows current gaps in uptake for sex, age and deprivation in a bowel cancer screening programme

Digby, J., McDonald, P. J., Strachan, J. A., Libby, G., Steele, R. JC. & Fraser, C. G., Jun 2013, In : Journal of Medical Screening. 20, 2, p. 80-85 6 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2012

A future for faecal haemoglobin measurements in the medical laboratory

Fraser, C. G., Nov 2012, In : Annals of Clinical Biochemistry. 49, 6, p. 518-526 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

A proposal to standardize reporting units for fecal immunochemical tests for hemoglobin

Fraser, C. G., Allison, J. E., Halloran, S. P. & Young, G. P., 2012, In : Journal of the National Cancer Institute. 104, 11, p. 810-814 5 p.

Research output: Contribution to journalArticle

108 Citations (Scopus)

Experience with a two-tier reflex gFOBT/FIT strategy in a national bowel screening programme

Fraser, C. G., Digby, J., McDonald, P. J., Strachan, J. A., Carey, F. A. & Steele, R. J. C., 2012, In : Journal of Medical Screening. 19, 1, p. 8-13 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Faecal haemoglobin concentrations by gender and age: implications for population-based screening for colorectal cancer

McDonald, P. J., Strachan, J. A., Digby, J., Steele, R. J. C. & Fraser, C. G., May 2012, In : Clinical Chemistry and Laboratory Medicine. 50, 5, p. 935-940 6 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)