Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Chiara Maniaci is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Cleave to Modify: Illuminating the "Dark Proteome" with Novel Chemical Biology Tools (Fellowship)
Maniaci, C. (Investigator)
1/01/24 → 31/12/31
Project: Research
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Liam Hales_Newton international fellowship with Chiara Maniaci
Maniaci, C. (Investigator)
Project: Research
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Regulation of Protein Stbility by Lysine Hydroxylation (DP Fellowship) (Transfer)
Maniaci, C. (Investigator)
Biotechnology and Biological Sciences Research Council
5/01/23 → 31/12/23
Project: Research
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Unravelling Key Cellular Machinery for Splicesome Regulation (Transfer)
Maniaci, C. (Investigator)
1/01/23 → 31/03/24
Project: Research
Research output
- 4 Article
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DEGRONOPEDIA: a web server for proteome-wide inspection of degrons
Szulc, N. A. (Lead / Corresponding author), Stefaniak, F., Piechota, M., Soszyńska, A., Piórkowska, G., Cappannini, A., Bujnicki, J. M., Maniaci, C. & Pokrzywa, W. (Lead / Corresponding author), 5 Jul 2024, In: Nucleic Acids Research. 52, W1, p. W221-W232 12 p., gkae238.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)76 Downloads (Pure) -
Targeted protein degradation via intramolecular bivalent glues
Hsia, O., Hinterndorfer, M., Cowan, A. D., Iso, K., Ishida, T., Sundaramoorthy, R., Nakasone, M. A., Imrichova, H., Schätz, C., Rukavina, A., Husnjak, K., Wegner, M., Correa-Sáez, A., Craigon, C., Casement, R., Maniaci, C., Testa, A., Kaulich, M., Dikic, I. & Winter, G. E. (Lead / Corresponding author) & 1 others, , 7 Mar 2024, In: Nature. 627, 8002, p. 204-211 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile71 Citations (Scopus)168 Downloads (Pure) -
Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms
Grohmann, C., Magtoto, C. M., Walker, J. R., Chua, N. K., Gabrielyan, A., Hall, M., Cobbold, S. A., Mieruszynski, S., Brzozowski, M., Simpson, D. S., Dong, H., Dorizzi, B., Jacobsen, A. V., Morrish, E., Silke, N., Murphy, J. M., Heath, J. K., Testa, A., Maniaci, C. & Ciulli, A. & 3 others, , 19 Apr 2022, In: Nature Communications. 13, p. 1-13 13 p., 2073.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)154 Downloads (Pure) -
The bromodomain and extra-terminal domain degrader MZ1 exhibits preclinical anti-tumoral activity in diffuse large B-cell lymphoma of the activated B cell-like type
Tarantelli, C., Cannas, E., Ekeh, H., Moscatello, C., Gaudio, E., Cascione, L., Napoli, S., Rech, C., Testa, A., Maniaci, C., Rinaldi, A., Zucca, E., Stathis, A., Ciulli, A. & Bertoni, F. (Lead / Corresponding author), 31 Dec 2021, In: Exploration of Targeted Anti-tumor Therapy. 2, 6, p. 586-601 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)123 Downloads (Pure)
Activities
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New York University
Maniaci, C. (Visiting researcher)
15 Jun 2024Activity: Visiting an external institution types › Visiting an external academic institution
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Honours Year Symposium - viva and poster assessor
Maniaci, C. (Examiner)
9 Dec 2024 → 12 Dec 2024Activity: Examination types › Examination
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Essays in Biochemistry (Journal)
Maniaci, C. (Editorial board member)
15 Oct 2024 → 31 Dec 2025Activity: Publication peer-review and editorial work types › Editorial activity
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It is all about Chemistry: the amazing science of everyday life
Maniaci, C. (Speaker)
3 Oct 2024Activity: Talk or presentation types › Keynote
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“Cleave to Modify”: A new biological mechanism for protein regulation
Maniaci, C. (Speaker)
5 Jul 2024Activity: Talk or presentation types › Invited talk