Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Chiara Maniaci is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Cleave to Modify: Illuminating the "Dark Proteome" with Novel Chemical Biology Tools (Fellowship)
Maniaci, C. (Investigator)
1/01/24 → 31/12/31
Project: Research
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Liam Hales_Newton international fellowship with Chiara Maniaci
Maniaci, C. (Investigator)
Project: Research
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Regulation of Protein Stbility by Lysine Hydroxylation (DP Fellowship) (Transfer)
Maniaci, C. (Investigator)
Biotechnology and Biological Sciences Research Council
5/01/23 → 31/12/23
Project: Research
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Unravelling Key Cellular Machinery for Splicesome Regulation (Transfer)
Maniaci, C. (Investigator)
1/01/23 → 31/03/24
Project: Research
Research output
- 4 Article
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DEGRONOPEDIA: a web server for proteome-wide inspection of degrons
Szulc, N. A. (Lead / Corresponding author), Stefaniak, F., Piechota, M., Soszyńska, A., Piórkowska, G., Cappannini, A., Bujnicki, J. M., Maniaci, C. & Pokrzywa, W. (Lead / Corresponding author), 5 Jul 2024, In: Nature Communications. 52, W1, p. W221-W232 12 p., gkae238.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)33 Downloads (Pure) -
Targeted protein degradation via intramolecular bivalent glues
Hsia, O., Hinterndorfer, M., Cowan, A. D., Iso, K., Ishida, T., Sundaramoorthy, R., Nakasone, M. A., Imrichova, H., Schätz, C., Rukavina, A., Husnjak, K., Wegner, M., Correa-Sáez, A., Craigon, C., Casement, R., Maniaci, C., Testa, A., Kaulich, M., Dikic, I. & Winter, G. E. (Lead / Corresponding author) & 1 others, , 7 Mar 2024, In: Nature. 627, 8002, p. 204-211 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Citations (Scopus)96 Downloads (Pure) -
Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms
Grohmann, C., Magtoto, C. M., Walker, J. R., Chua, N. K., Gabrielyan, A., Hall, M., Cobbold, S. A., Mieruszynski, S., Brzozowski, M., Simpson, D. S., Dong, H., Dorizzi, B., Jacobsen, A. V., Morrish, E., Silke, N., Murphy, J. M., Heath, J. K., Testa, A., Maniaci, C. & Ciulli, A. & 3 others, , 19 Apr 2022, In: Nature Communications. 13, p. 1-13 13 p., 2073.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)100 Downloads (Pure) -
The bromodomain and extra-terminal domain degrader MZ1 exhibits preclinical anti-tumoral activity in diffuse large B-cell lymphoma of the activated B cell-like type
Tarantelli, C., Cannas, E., Ekeh, H., Moscatello, C., Gaudio, E., Cascione, L., Napoli, S., Rech, C., Testa, A., Maniaci, C., Rinaldi, A., Zucca, E., Stathis, A., Ciulli, A. & Bertoni, F. (Lead / Corresponding author), 31 Dec 2021, In: Exploration of Targeted Anti-tumor Therapy. 2, 6, p. 586-601 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)106 Downloads (Pure)
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RSC Chemical Biology (Journal)
Maniaci, C. (Peer reviewer)
Aug 2023Activity: Publication peer-review and editorial work types › Publication peer-review
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Ingrid E. Wertz
Maniaci, C. (Host)
12 May 2023Activity: Hosting a visitor types › Hosting a non-academic visitor
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“Cleave-to-modify”: shining light on the dark proteome
Maniaci, C. (Speaker)
22 Mar 2023Activity: Talk or presentation types › Invited talk
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Cell Reports Medicine (Journal)
Maniaci, C. (Peer reviewer)
7 Jun 2023Activity: Publication peer-review and editorial work types › Publication peer-review