• 3229 Citations
  • 18 h-Index
20082019
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Personal profile

Biography

Christian Cole is a Principal Investigator at the Leverhulme Research Centre for Forensic Science (LRCFS). His expertise and passion is in Bioinformatics and Data Science gained over his postdoctoral career at UMIST, The University of Manchester and, most recently, within the School of Life Sciences at the University of Dundee. In that time, Chris was the founder member and latterly the co-ordinator of the Data Analysis Group; a team dedicated to collaboration on biological projects requiring computational and statistical direction. At LRCFS Chris will be using his multi-disciplinary computational approaches to challenge existing weaknesses in the analysis and interpretation of several forensic evidence types. Chris has a BSc in Pharmaceutical Chemistry and a PhD in Medicinal Chemistry.

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Projects 2017 2019

RSE Cloud Computing Award

Cole, C.

13/11/1712/11/19

Project: Research

Research Output 2008 2019

EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis

Elias, M. S., Wright, S. C., Remenyi, J., Abbott, J. C., Bray, S. E., Cole, C., Edwards, S., Gierlinski, M., Glok, M., McGrath, J. A., Nicholson, W. V., Paternoster, L., Prescott, A. R., Have, S. T., Whitfield, P. D., Lamond, A. I. & Brown, S. J., Aug 2019, In : Journal of Allergy and Clinical Immunology. 144, 2, p. 470-481 12 p.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Skin
Genome-Wide Association Study
Keratinocytes
Skin Diseases
157 Downloads (Pure)

Proteus: an R package for downstream analysis of MaxQuant output

Gierlinski, M., Gastaldello, F., Cole, C. & Barton, G., 20 Sep 2018, In : BioRxiv. 10 p.

Research output: Contribution to journalArticle

Open Access
File
Proteus
Peptides
Mass Spectrometry
Proteins

Reformatter for EMBL's HLA aligner

Cole, C. & Mudie, R., 29 May 2018

Research output: Non-textual formSoftware

Polymorphism
Databases
3 Citations (Scopus)
101 Downloads (Pure)
Open Access
File
Dictyostelium
Adenylyl Cyclases
Genes
Cell Movement
bis(3',5')-cyclic diguanylic acid
5 Citations (Scopus)
128 Downloads (Pure)

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis

Naeem, A. S., Tommasi, C., Cole, C., Brown, S. J., Zhu, Y., Way, B., Willis Owen, S. A. G., Moffatt, M., Cookson, W. O., Harper, J. I., Di, W. L., Brown, S. J., Reinheckel, T. & O'Shaughnessy, R. F. L., Apr 2017, In : Journal of Allergy and Clinical Immunology. 139, 4, p. 1228-1241 14 p.

Research output: Contribution to journalArticle

Open Access
File
Cathepsin H
Thymoma
Atopic Dermatitis
Oncogenes
Skin

Prizes

Winner ISCB Art in Science Competition 2017

Christian Cole (Recipient) & Nicholas Schurch (Recipient), 25 Jul 2017

Prize: Prize (including medals and awards)

Computational
Bioinformatics
Art
Artwork
Computer Science

Activities 2018 2019

  • 3 Participation in workshop, seminar, course
  • 3 Invited talk
  • 2 Public engagement and outreach - festival/exhibition

The Leverhulme Research Centre for Forensic Science

Christian Cole (Speaker)
15 Feb 2019

Activity: Talk or presentation typesInvited talk

Forensic Data Hackathon

Christian Cole (Organiser)
11 Mar 201922 Mar 2019

Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

Presentation to CodeClan Students

Christian Cole (Speaker)
13 Mar 2019

Activity: Talk or presentation typesInvited talk

CodeClan Data For Detectives DataFest19 event

Christian Cole (Presenter), Niamh Nic Daeid (Presenter), Heather Doran (Presenter)
13 Mar 2019

Activity: Other activity typesPublic engagement and outreach - festival/exhibition

Putting the Science Back Into Forensic Science

Christian Cole (Speaker)
30 Apr 2019

Activity: Talk or presentation typesInvited talk

Press / Media

Lords inquiry says forensic science is broken: here’s how we can start to fix it

Niamh Nic Daeid, Michael Marra, Christian Cole, Emma Comrie & Heather Doran

3/05/1921/08/19

2 Media contributions

Press/Media: Research

Is Reproducible Science Well Understood in Forensic Science?

Christian Cole

14/08/18

1 item of Media coverage

Press/Media: Research

Rare skin disease gene discovered

Elizabeth Pohler, Alan Irvine, Toshifumi Nomura, John A. McGrath, W. H. Irwin McLean, Neil Wilson, Frances J. D. Smith, Aileen Sandilands, Christian Cole, Alan Evans, Sara J. Brown & David R. Goudie

15/10/12

1 item of Media coverage

Press/Media: Research