Projects per year
Personal profile
Biography
Professor Barratt is Head of Division Post Graduate Medicine , Head of the Reproductive Medicine Group at the University of Dundee as well as a clinical scientist (Hon) with NHS Tayside. He graduated with an Honours degree in Zoology and then completed a Post Graduate Certificate in Education (University of Wales, Swansea). His PhD, also in Zoology, was under the supervision of Jack Cohen at the University of Birmingham.
His formative post-doctoral studies and ART experience was gained at the University of Sheffield [with Ian Cooke] where they specialized in natural cycle IVF. From 1997-2005 he was the Scientific Director of the ART Centre at the Birmingham Women’s Hospital.
Professor Barratt has been awarded a number of honors for outstanding contributions to the discipline e.g. Young Andrologist of the Year (American Andrology Society), the Professor Sir Robert Edwards keynote lecture at ESHRE. He was awarded a DSc from University of Birmingham and has a h index of 57 (Scopus 2022). Professor Barratt is a Fellow of the Royal Society of Edinburgh.
He is a regularly invited speaker at national and international scientific conferences/workshops. He was a member of the WHO Male Fertility Semen Analysis Taskforce (for both the 4th and 5th editions) and director of the WHO (2012-2017) Male Fertility Expert Working Group which devised a new system for the diagnosis and treatment of the infertile male. He was a member of the Human Fertilisation and Embryology Authority for 6 years until 2009.
Professor Barratt has been appointed to editorial board of WHO for development of new Semen Analysis manual (6th edition, publication date late 2021). He recently published the global WHO guidelines for semen reference ranges.
He has been on the Editorial Board of Human Reproduction, Human Fertility, Biology of Reproduction, Human Reproduction Update, Journal of Andrology and was Editor-in-Chief of Molecular Human Reproduction from 2013-2018. Currently he is a member of the Editorial board of Physiological Reviews.
He is a member of the reviewing editors for Science (AAAS) https://www.science.org/
Professor Barratt is helping coordinating the Global Initiative on Male Reproductive Health.
Research
We are primarily focused on understanding the function of the human spermatozoa and identifying the key factors in the process of sperm egg interation.
Our research uses cutting edge technology combined with selected samples from patients with well-defined pathology. As such the research has a very strong translational focus.
Our primary collaborators in Dundee are the IVF clinic at NHS Tayside, Abertay University's Dr Sean Brown, Professor Paul Wyatt (Drug Discovery Unit, SLS), and Paul Andrews (National Phenotypic Screening Centre, SLS)
We are funded by NHS Tayside, MRC, Chief Scientists Office (Scotland), Astra Zeneca and the Bill and Melinda Gates Foundation.
We regularly contribute to public debates on reproductive issues: e.g. impact of male age https://www.bionews.org.uk/page_135205
Patents
- Inventor: Barratt C (CMDN) & Wyatt PG (CLS) ‘Stimulation of human sperm motility’. International application number: PCT/GB2012/052514. Publication number WO/2013/054111. Publication date 18th April 2013.
- Inventor: Genosis & Barratt C ‘Method and detection kit for male infertility’ 1999. WO/99066331
Teaching
Professor Barratt has supervised 29 MSc, PhD, MD students almost all of whom work in in the field of reproductive medicine.
His teaching consists of:
Supervisor: 9 MSc/PhD students
Leader: SSC in Stem Cells and Assisted Conception
Leader: Human Reproduction, Assisted Conception and Embryonic Stem Cells BMSc
Leader: Human Clinical Embryology and Assisted Conception MSc.
External examiner (previous)
• Quinquennial Review MSc for ART at University of Oxford (2014).
• MSc for Reproductive and Developmental Biology at University of Edinburgh (2009-2013).
• United Arab Emirates Ministry of Higher Education and Scientific Research (2012-2013).
• 3rd year Reproductive Biology course at University of Edinburgh (2015-16).
• Endocrine and Reproduction Course (MDSC 2101) University West Indies 2014-2017.
• University of Nottingham (2004-2006).
• MSc in Embryology at the University of Leeds (2002-2004).
• MSc ART University of Bristol (2002-2005).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Advancement of Sperm-targeting Contraceptive Agents
Barratt, C. (Investigator), Gilbert, I. (Investigator), Martins Da Silva, S. (Investigator), Read, K. (Investigator), Swedlow, J. (Investigator) & Wyllie, S. (Investigator)
Bill and Melinda Gates Foundation
5/07/23 → 4/07/26
Project: Research
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Male Contraceptive Drug Development Using a Novel Human Sperm Phenotypic Screening Platform (Grand Challenges Phase II)
Andrews, P. (Investigator), Barratt, C. (Investigator), Gilbert, I. (Investigator), Martins Da Silva, S. (Investigator), Read, K. (Investigator) & Swedlow, J. (Investigator)
Bill and Melinda Gates Foundation
1/11/18 → 30/09/23
Project: Research
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Development and Validation of a Screening Test to Predict the Likelihood of Fertilisation Failure Caused by Sperm Ion Channel Dysfunction (ICD) (Joint with University of Abertay and NHS Tayside)
Barratt, C. (Investigator) & Martins Da Silva, S. (Investigator)
1/05/18 → 30/09/21
Project: Research
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Novel Phenotypic Drug Discovery for Contraception
Barratt, C. (Investigator), Hopkins, A. (Investigator) & Martins Da Silva, S. (Investigator)
Bill and Melinda Gates Foundation
1/11/16 → 31/10/18
Project: Research
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Ca2+ Signalling in Regulation and Therapeutic Manipulation of Human Sperm Behaviour (Joint with University of Birmingham and University of Abertay)
Barratt, C. (Investigator)
1/10/15 → 31/12/17
Project: Research
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APHRODITE criteria: addressing male patients with hypogonadism and/or infertility owing to altered idiopathic testicular function
Esteves, S. C. (Lead / Corresponding author), Humaidan, P., Ubaldi, F. M., Alviggi, C., Antonio, L., Barratt, C. L. R., Behre, H. M., Jørgensen, N., Pacey, A. A., Simoni, M. & Santi, D., Apr 2024, In: Reproductive BioMedicine Online. 48, 4, 18 p., 103647.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)39 Downloads (Pure) -
Frequency, morbidity and equity - the case for increased research on male fertility
Kimmins, S., Anderson, R. A., Barratt, C. L. R., Behre, H. M., Catford, S. R., De Jonge, C. J., Delbes, G., Eisenberg, M. L., Garrido, N., Houston, B. J., Jørgensen, N., Krausz, C., Lismer, A., McLachlan, R. I., Minhas, S., Moss, T., Pacey, A., Priskorn, L., Schlatt, S. & Trasler, J. & 6 others, , Feb 2024, In: Nature Reviews Urology. 21, 2, p. 102-124Research output: Contribution to journal › Review article › peer-review
12 Citations (Scopus) -
Sperm Toolbox-A selection of small molecules to study human spermatozoa
Gruber, F. S., Richardson, A., Johnston, Z. C., Myles, R., Norcross, N. R., Day, D. P., Georgiou, I., Sesma-Sanz, L., Wilson, C., Read, K. D., Martins da Silva, S., Barratt, C. L. R., Gilbert, I. H. & Swedlow, J. R. (Lead / Corresponding author), 20 Feb 2024, In: PLoS ONE. 19, 2, 16 p., e0297666.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Downloads (Pure) -
Surfing a shallow wave? Improving the scientific foundations for new contraceptive compounds targeting sperm in the human female reproductive tract
Gellatly, S. A., Eisenberg, M. L. & Barratt, C. L. R., 11 Apr 2024, (E-pub ahead of print) In: Fertility and Sterility. 2 p.Research output: Contribution to journal › Editorial › peer-review
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Practice and development of male contraception: European Academy of Andrology and American Society of Andrology guidelines
Wang, C., Meriggiola, M. C., Amory, J. K., Barratt, C. L. R., Behre, H. M., Bremner, W. J., Ferlin, A., Honig, S., Kopa, Z., Lo, K., Nieschlag, E., Page, S. T., Sandlow, J., Sitruk-Ware, R., Swerdloff, R. S., Wu, F. C. W. & Goulis, D. G. (Lead / Corresponding author), 20 Sept 2023, (E-pub ahead of print) In: Andrology. 31 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus)
Datasets
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Research funding for male reproductive health and infertility in the UK and USA [2016 – 2019]
Gumerova, E. (Creator), De Jonge, C. (Creator) & Barratt, C. (Creator), Dryad, 1 Mar 2022
DOI: 10.5061/dryad.v9s4mw6wc, https://datadryad.org/stash/dataset/doi:10.5061/dryad.v9s4mw6wc
Dataset
Activities
- 1 Examination
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PhD Viva of Abdullah Arafah
Murdoch, C. (Examiner), Delas, C. (Examiner) & Barratt, C. (Advisor)
12 Mar 2024Activity: Examination types › Examination