Barratt, Christopher

Professor, Head of Division Systems Medicine

  • 7854 Citations
  • 50 h-Index
1986 …2021
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Personal profile

Biography

Professor Barratt is Head of Division Systems Medicine, Head of the Reproductive Medicine Group at the University of Dundee as well as a clinical scientist (Hon) with NHS Tayside. He graduated with an Honours degree in Zoology and then completed a Post Graduate Certificate in Education (University of Wales, Swansea). His PhD, also in Zoology, was under the supervision of Jack Cohen at the University of Birmingham.

His formative post-doctoral studies and ART experience was gained at the University of Sheffield [with Ian Cooke] where they specialized in natural cycle IVF. From 1997-2005 he was the Scientific Director of the ART Centre at the Birmingham Women’s Hospital.

Professor Barratt has been awarded a number of honors for outstanding contributions to the discipline e.g. Young Andrologist of the Year (American Andrology Society), the Professor Sir Robert Edwards keynote lecture at ESHRE.

He is a regularly invited speaker at national and international scientific conferences/workshops. He was a member of the WHO Male Fertility Semen Analysis Taskforce (for both the 4th and 5th editions) and director of the WHO (2012-2017) Male Fertility Expert Working Group which devised a new system for the diagnosis and treatment of the infertile male  (https://academic.oup.com/humupd/article/23/6/660/3979420). He was a member of the Human Fertilisation and Embryology Authority for 6 years.

Professor Barratt has recently been appointed to editorial board of WHO for development of new Semen Analysis manual (6th edition).

He has been on the Editorial Board of Human Reproduction, Human Fertility, Biology of Reproduction, Human Reproduction Update, Journal of Andrology and is currently Editor-in-Chief of Molecular Human Reproduction (Impact factor 5 year 3.6)

 

His life’s ambition is to see - live - Wales comprehensively beat the All Blacks.

Research

We are primarily focused on understanding the function of the human spermatozoa and identifying the key factors in the process of sperm egg interation.

Our research uses cutting edge technology combined with selected samples from patients with well-defined pathology. As such the research has a very strong translational focus.

Our primary collaborators in Dundee are the IVF clinic at NHS Tayside, Abertay University's Dr Sean Brown, Professor Paul Wyatt (Drug Discovery Unit, SLS), and Paul Andrews (National Phenotypic Screening Centre, SLS http://npsc.ac.uk/)

We are funded by NHS Tayside, MRC, Chief Scientists Office (Scotland), Astra Zeneca and the Bill and Melinda Gates Foundation.

We regularly contribute to public debates on reproductive issues: e.g. impact of male age https://www.bionews.org.uk/page_135205

Patents

  • Inventor: Barratt C (CMDN) & Wyatt PG (CLS) ‘Stimulation of human sperm motility’. International application number: PCT/GB2012/052514. Publication number WO/2013/054111. Publication date 18th April 2013.
  • Inventor: Genosis & Barratt C ‘Method and detection kit for male infertility’ 1999. WO/99066331

Teaching

Professor Barratt has supervised 29 MSc, PhD, MD students almost all of whom work in in the field of reproductive medicine.

His teaching consists of:

Supervisor: 9 MSc/PhD students

Leader: SSC in Stem Cells and Assisted Conception

Leader: Human Reproduction, Assisted Conception and Embryonic Stem Cells BMSc

Leader: Human Clinical Embryology and Assisted Conception MSc.

 

External examiner (previous)

  • Quinquennial Review MSc for ART at University of Oxford (2014).
  • MSc for Reproductive and Developmental Biology at University of Edinburgh (2009-2013).
  • United Arab Emirates Ministry of Higher Education and Scientific Research (2012-2013).
  • 3rd year Reproductive Biology course at University of Edinburgh (2015-16).
  • Endocrine and Reproduction Course (MDSC 2101) University West Indies 2014-2017.
  • University of Nottingham (2004-2006).
  • MSc in Embryology at the University of Leeds (2002-2004).
  • MSc ART University of Bristol (2002-2005).

Fingerprint Dive into the research topics where Christopher Barratt is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Spermatozoa Medicine & Life Sciences
Acrosome Reaction Medicine & Life Sciences
Semen Medicine & Life Sciences
Fertility Medicine & Life Sciences
Infertility Medicine & Life Sciences
Progesterone Medicine & Life Sciences
Fertilization Medicine & Life Sciences
Sperm Motility Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1986 2019

17 Downloads (Pure)

Continuous behavioural 'switching' in human spermatozoa and its regulation by Ca2+-mobilising stimuli

Achikanu, C., Correia, J., Guidobaldi, H., Giojalas, L., L R Barratt, C., Da Silva, S. M. & Publicover, S., 13 Jun 2019, In : Molecular Human Reproduction. gaz034.

Research output: Contribution to journalArticle

Open Access
File
Spermatozoa
Sperm Head
Follicular Fluid
4-Aminopyridine
Fractals

Novel pharmacological actions of Trequinsin Hydrochloride improve human sperm cell motility and function

McBrinn, R. C., Fraser, J., Hope, A. G., Gray, D. W., Barratt, C. L. R., Martins da Silva, S. J. & Brown, S. G., 1 Aug 2019, In : British Journal of Pharmacology.

Research output: Contribution to journalArticle

Sperm Motility
Cell Movement
Pharmacology
Spermatozoa
Electrophysiology
34 Downloads (Pure)

The Present Crisis in Male Reproductive Health: An Urgent Need for a Political, Social, and Research Roadmap

De Jonge, C. J. & Barratt, C., 26 Jun 2019, In : Andrology. 7 p.

Research output: Contribution to journalArticle

Open Access
File
Reproductive Health
Research
Paternal Age
Male Infertility
Delivery of Health Care
3 Downloads (Pure)

A Dolce & Gabbana model in every ART clinic?

Barratt, C. L. R., Sep 2018, In : Molecular Human Reproduction. 24, 9, p. 431-432 2 p.

Research output: Contribution to journalEditorial

Open Access
File
6 Downloads (Pure)

Education, education, education: now more than ever?

Andersen, C. Y., Kristensen, S. G., Mamsen, L. S. & Barratt, C., 1 Aug 2018, In : Molecular Human Reproduction. 24, 8, p. 426-429 4 p.

Research output: Contribution to journalArticle

Open Access
File
Education
Infertility
Reproduction
Birth Order
Ovulation Induction

Thesis

Acrosomal molecules exposure during human sperm capacitation

Author: Fouriki, T., 2013

Supervisor: Barratt, C. (Supervisor)

Student thesis: Master's ThesisMaster of Science

File

CatSper: Characterisation in Human Spermatozoa and Clinical Significance

Author: Williams, H. L., 2016

Supervisor: Barratt, C. (Supervisor) & Martins Da Silva, S. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Compounds Modulating Calcium and Motility in Human Spermatozoa

Author: Cochrane, C., 2015

Supervisor: Barratt, C. (Supervisor) & Martins Da Silva, S. (Supervisor)

Student thesis: Master's ThesisMaster of Science

File

Hyperactivated motility in human sperm: regulation, function and significance in IVF

Author: Foster, E., 2011

Supervisor: Barratt, C. (Supervisor)

Student thesis: Master's ThesisMaster of Science

File

Investigating the clinical value of hyperactivation and intracellular calcium signalling of human spermatozoa and their value in drug screening

Author: Ruso, H., 2013

Supervisor: Martins Da Silva, S. (Supervisor) & Barratt, C. (Supervisor)

Student thesis: Master's ThesisMaster of Science

File