• 2724 Citations
  • 30 h-Index
19952017
If you made any changes in Pure these will be visible here soon.

Research Output 1995 2017

2017

Environmental Pharmacology: how safe is our chemical jungle?

Connolly, C., 20 Oct 2017, 1 p. London : Biochemical Society.

Research output: Other contribution

Open Access
pest species
monoculture
food supply
industrialization
agriculture
935 Downloads (Pure)

Honeybee colony losses and threats in Scotland. (2012-2017)

Connolly, C. & Durkacz, J., 6 Oct 2017, 9 p. United Kindgom : University of Dundee.

Research output: Other contribution

Open Access
File
honey bee colonies
Scotland
winter
2 Citations (Scopus)
87 Downloads (Pure)

Nerve agents in honey: Analysis of local honey samples shows global landscape contamination by pesticides

Connolly, C., 6 Oct 2017, In : Science. 358, 6359, p. 38-39 2 p.

Research output: Contribution to journalArticle

Open Access
File
Honey
Bees
Pesticides
Ecosystem
Pollination
91 Citations (Scopus)
599 Downloads (Pure)

Subcallosal cingulate deep brain stimulation for treatment-resistant depression: a multi-site, randomized, sham-controlled trial

Holtzheimer, P., Husain, M. M., Lisanby, S. H., Taylor, S. F., Whitworth, L. A., McClintock, S., Slavin, K. V., Berman, J., McKhann, G. M., Patil, P. G., Rittberg, B. R., Abosch, A., Pandurangi, A. K., Holloway, K. L., Lam, R. W., Connolly, C., Neimat, J. S., Henderson, J. M., DeBattista, C., Rothschild, A. J. & 10 others, Pilitsis, J. G., Espinoza, R. T., Petrides, G., Mogilner, A. Y., Matthews, K., Peichel, D., Grosse, R., Hamani, C., Lozano, A. M. & Mayberg, H. S., Nov 2017, In : Lancet Psychiatry. 4, 11, p. 839-849 11 p.

Research output: Contribution to journalArticle

Open Access
File
Treatment-Resistant Depressive Disorder
Deep Brain Stimulation
Randomized Controlled Trials
Medical Futility
Depression
2016
35 Citations (Scopus)
175 Downloads (Pure)

Neonicotinoids target distinct nicotinic acetylcholine receptors and neurons, leading to differential risks to bumblebees

Moffat, C., Buckland, S. T., Samson, A., McArthur, R., Chamosa Pino, V., Bollan, K. A., Huang, J. T-J. & Connolly, C., 28 Apr 2016, In : Scientific Reports. 6, p. 1-10 10 p., 24764.

Research output: Contribution to journalArticle

Open Access
File
Nicotinic Receptors
Bees
Neurons
Aptitude
Food Supply
10 Citations (Scopus)
121 Downloads (Pure)

Neuronal networks provide rapid neuroprotection against spreading toxicity

Samson, A. J., Robertson, G., Zagnoni, M. & Connolly, C. N., 21 Sep 2016, In : Scientific Reports. 6, p. 1-11 11 p., 33746.

Research output: Contribution to journalArticle

Open Access
File
Lab-On-A-Chip Devices
Glutamic Acid
Stroke
Emergency Treatment
Brain
2015
43 Citations (Scopus)
208 Downloads (Pure)

Chronic exposure to neonicotinoids increases neuronal vulnerability to mitochondrial dysfunction in the bumblebee (Bombus terrestris)

Moffat, C., Pacheco, J. G., Sharp, S., Samson, A. J., Bollan, K. A., Huang, J., Buckland, S. T. & Connolly, C. N., May 2015, In : FASEB Journal. 29, 5, p. 2112-2119 8 p.

Research output: Contribution to journalArticle

Open Access
File
Depolarization
Neurons
Brain
Plant Nectar
Bees
2014
2 Citations (Scopus)
85 Downloads (Pure)

5-hydroxytryptamine (5-HT) cellular sequestration during chronic exposure delays 5-HT3 receptor resensitization due to Its subsequent release

Hothersall, J. D., Alexander, A., Samson, A. J., Moffat, C., Bollan, K. A. & Connolly, C. N., 14 Nov 2014, In : Journal of Biological Chemistry. 289, 46, p. 32020-32029 10 p.

Research output: Contribution to journalArticle

Open Access
File
Serotonin Receptors
Serotonin
Down-Regulation
Ileum
Serotonin Plasma Membrane Transport Proteins
2013
112 Citations (Scopus)

Cholinergic pesticides cause mushroom body neuronal inactivation in honeybees

Palmer, M. J., Moffat, C., Saranzewa, N., Harvey, J., Wright, G. A. & Connolly, C. N., 27 Mar 2013, In : Nature Communications. 4, 1634.

Research output: Contribution to journalArticle

Open Access
cholinergics
Mushroom Bodies
pesticides
Pesticides
deactivation
39 Citations (Scopus)
165 Downloads (Pure)

Exposure to acetylcholinesterase inhibitors alters the physiology and motor function of honeybees

Williamson, S. M., Moffat, C., Gomersall, M. A. E., Saranzewa, N., Connolly, C. N. & Wright, G. A., 5 Feb 2013, In : Frontiers in Physiology. 4, 13.

Research output: Contribution to journalArticle

Open Access
File
Grooming
Cholinesterase Inhibitors
Coumaphos
Pesticides
Cholinergic Agents
14 Citations (Scopus)

Prolonged inhibition of 5-HT3 receptors by palonosetron results from surface receptor inhibition rather than inducing receptor internalization

Hothersall, J. D., Moffat, C. & Connolly, C. N., Jul 2013, In : British Journal of Pharmacology. 169, 6, p. 1252-1262 11 p.

Research output: Contribution to journalArticle

Receptors, Serotonin, 5-HT3
Granisetron
Down-Regulation
Binding Sites
Endocytosis
15 Citations (Scopus)

The microsporidian parasites Nosema ceranae and Nosema apis are widespread in honeybee (Apis mellifera) colonies across Scotland

Bollan, K. A., Hothersall, J. D., Moffat, C., Durkacz, J., Saranzewa, N., Wright, G. A., Raine, N. E., Highet, F. & Connolly, C. N., Feb 2013, In : Parasitology Research. 112, 2, p. 751-759 9 p.

Research output: Contribution to journalArticle

Nosema
Nosema apis
Nosema ceranae
Bees
Microsporidia

The risk of insecticides to pollinating insects

Connolly, C. N., Sep 2013, In : Communicative & Integrative Biology. 6, 5, 3 p., e25074.

Research output: Contribution to journalArticle

neonicotinoid insecticides
pollinating insects
Insecticides
Insects
insecticides
2012

A new approach to authorship: shared responsibility and shared credit

Connolly, C. N., Dec 2012, In : Journal of the Royal Society of Medicine. 105, 12, p. 501-502 2 p.

Research output: Contribution to journalLetter

11 Citations (Scopus)

High-affinity fluorescent ligands for the 5-HT3 receptor

Simonin, J., Vernekar, S. K. V., Thompson, A. J., Hothersall, J. D., Connolly, C. N., Lummis, S. C. R. & Lochner, M., 2012, In : Bioorganic & Medicinal Chemistry Letters. 22, 2, p. 1151-1155 5 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Identifying key knowledge needs for evidence-based conservation of wild insect pollinators: a collaborative cross-sectoral exercise

Dicks, L. V., Abrahams, A., Atkinson, J., Biesmeijer, J., Bourn, N., Brown, C., Brown, M. J. F., Carvell, C., Connolly, C., Cresswell, J. E., Croft, P., Darvill, B., De Zylva, P., Effingham, P., Fountain, M., Goggin, A., Harding, D., Harding, T., Hartfield, C., Heard, M. S. & 30 others, Heathcote, R., Heaver, D., Holland, J., Howe, M., Hughes, B., Huxley, T., Kunin, W. E., Little, J., Mason, C., Memmott, J., Osborne, J., Pankhurst, T., Paxton, R. J., Pocock, M. J. O., Potts, S. G., Power, E. F., Raine, N. E., Ranelagh, E., Roberts, S., Saunders, R., Smith, K., Smith, R. M., Sutton, P., Tilley, L. A. N., Tinsley, A., Tonhasca, A., Vanbergen, A. J., Webster, S., Wilson, A. & Sutherland, W. J., 2012, In : Insect Conservation and Diversity. 6, 3, p. 435-446 12 p.

Research output: Contribution to journalArticle

pollinating insects
pollinator
pollinators
exercise
insect
2011

2Bs or not 2Bs: that is the question

Connolly, C. N., 2011, In : Journal of Physiology. 589, 17, p. 4085-4086 2 p.

Research output: Contribution to journalArticle

2010

Impact of the chaperone RIC-3 on the expression of human 5-HT3 receptors: role of 5-HT3 B, C, D and E subunits

Walstab, J., Hammer, C., Lasitschka, F., Connolly, C., Rappold, G., Boenisch, H. & Niesler, B., Mar 2010, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 381, p. 16-16 1 p.

Research output: Contribution to journalBook/Film/Article review

71 Citations (Scopus)

Leptin Regulates AMPA Receptor Trafficking via PTEN Inhibition

Moult, P. R., Cross, A., Santos, S. D., Carvalho, A-L., Lindsay, Y., Connolly, C. N., Irving, A. J., Leslie, N. R. & Harvey, J., 17 Mar 2010, In : Journal of Neuroscience. 30, 11, p. 4088-4101 14 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

RIC-3 Exclusively Enhances the Surface Expression of Human Homomeric 5-Hydroxytryptamine Type 3A (5-HT(3)A) Receptors Despite Direct Interactions with 5-HT3A, -C, -D, and -E Subunits

Walstab, J., Hammer, C., Lasitschka, F., Möller, D., Connolly, C. N., Rappold, G., Bruess, M., Boenish, H. & Niesler, B., 27 Aug 2010, In : Journal of Biological Chemistry. 285, 35, p. 26956-26965 10 p.

Research output: Contribution to journalArticle

2009
6 Citations (Scopus)

Rapid dendritic and axonal responses to neuronal insults

Mizielinska, S. M., Greenwood, S. M., Tummala, H. & Connolly, C. N., Dec 2009, In : Biochemical Society Transactions. 37, p. 1389-1393 5 p.

Research output: Contribution to journalArticle

2008
27 Citations (Scopus)

The promiscuous role of the epsilon subunit in GABA(A) receptor biogenesis

Bollan, K. A., Baur, R., Hales, T. G., Sigel, E. & Connolly, C. N., Mar 2008, In : Molecular and Cellular Neuroscience. 37, 3, p. 610-621 12 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Trafficking of 5-HT3 and GABA(A) receptors (Review)

Connolly, C., 2008, In : Molecular Membrane Biology. 25, 4, p. 293-301 9 p.

Research output: Contribution to journalReview article

2007
64 Citations (Scopus)

An essential role for constitutive endocytosis, but not activity, in the axonal targeting of the CB1 cannabinoid receptor

McDonald, N. A., Henstridge, C. M., Connolly, C. N. & Irving, A. J., 2007, In : Molecular Pharmacology. 71, 4, p. 976-984 9 p.

Research output: Contribution to journalArticle

Cannabinoid Receptor CB1
Endocytosis
Neurons
Axons
Dynamin I
84 Citations (Scopus)

Dendritic and mitochondrial changes during glutamate excitotoxicity

Greenwood, S. M. & Connolly, C. N., Dec 2007, In : Neuropharmacology. 53, 8, p. 891-898 8 p.

Research output: Contribution to journalReview article

27 Citations (Scopus)

Differential subcellular localization of RIC-3 Isoforms and their role in determining 5-HT3 receptor composition

Cheng, A., Bollan, K. A., Greenwood, S. M., Irving, A. J. & Connolly, C. N., 7 Sep 2007, In : Journal of Biological Chemistry. 282, 36, p. 26158-26166 9 p.

Research output: Contribution to journalArticle

Receptors, Serotonin, 5-HT3
Protein Isoforms
Endoplasmic Reticulum
Chemical analysis
Agglomeration
22 Citations (Scopus)

Generation and functional characterization of fluorescent, N-terminally tagged CB1 receptor chimeras for live-cell imaging

McDonald, N. A., Henstridge, C. M., Connolly, C. N. & Irving, A. J., Jun 2007, In : Molecular and Cellular Neuroscience. 35, 2, p. 237-248 12 p.

Research output: Contribution to journalArticle

Cannabinoid Receptor CB1
HEK293 Cells
Cell Surface Receptors
Protein Sorting Signals
Fluorescence
121 Citations (Scopus)

Leptin promotes rapid dynamic changes in hippocampal dendritic morphology

O'Malley, D., MacDonald, N., Mizielinska, S., Connolly, C. N., Irving, A. J. & Harvey, J., Aug 2007, In : Molecular and Cellular Neuroscience. 35, 4, p. 559-572 14 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Mitochondrial dysfunction and dendritic beading during neuronal toxicity

Greenwood, S. M., Mizielinska, S. M., Frenguelli, B. G., Harvey, J. & Connolly, C. N., 7 Sep 2007, In : Journal of Biological Chemistry. 282, 36, p. 26235-26244 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Naturally occurring variations in the human 5-HT3A gene profoundly impact 5-HT3 receptor function and expression

Krzywkowski, K., Jensen, A. A., Connolly, C. N. & Brauner-Osborne, H., Apr 2007, In : Pharmacogenetics and Genomics. 17, 4, p. 255-266 12 p.

Research output: Contribution to journalArticle

2006
26 Citations (Scopus)

An asymmetric contribution to gamma-aminobutyric type a receptor function of a conserved lysine within TM2-3 of alpha 1, beta 2, and gamma 2 subunits

Hales, T. G., Deeb, T. Z., Tang, H., Bollan, K. A., King, D. P., Johnson, S. J. & Connolly, C. N., 23 Jun 2006, In : Journal of Biological Chemistry. 281, 25, p. 17034-17043 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The role of GABAA receptor biogenesis, structure and function in epilepsy

Mizielinska, S., Greenwood, S. & Connolly, C. N., 2006, In : Biochemical Society Transactions. 34, 5, p. 863-867 5 p.

Research output: Contribution to journalArticle

The role of GABAA receptor biogenesis, structure and function in epilepsy

Mizielinska, S., Greenwood, S. & Connolly, C. N., 2006.

Research output: Contribution to conferencePaper

2005
51 Citations (Scopus)

Cell surface expression of 5-hydroxytryptamine type 3 receptors is promoted by RIC-3

Cheng, A., McDonald, N. A. & Connolly, C. N., 10 Jun 2005, In : Journal of Biological Chemistry. 280, 23, p. 22502-22507 6 p.

Research output: Contribution to journalArticle

Receptors, Serotonin, 5-HT3
Serotonin
Endoplasmic Reticulum
Serotonin Receptors
Nicotinic Receptors
35 Citations (Scopus)

Cellular and subcellular calcium accumulation during glutamate-induced injury in cerebellar granule neurons

Ward, M. W., Kushnareva, Y., Greenwood, S. & Connolly, C. N., 2005, In : Journal of Neurochemistry. 92, 5, p. 1081-1090 10 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

The epilepsy mutation, γ2(R43Q) disrupts a highly conserved inter-subunit contact site, perturbing the biogenesis of GABAA receptors

Hales, T. G., Tang, H., Bollan, K. A., Johnson, S. J., King, D. P., McDonald, N. A., Cheng, A. & Connolly, C. N., 2005, In : Molecular and Cellular Neuroscience. 29, 1, p. 120-127 8 p.

Research output: Contribution to journalArticle

2004
194 Citations (Scopus)

GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons

Cole, A. R., Knebel, A., Morrice, N. A., Robertson, L. A., Irving, A. J., Connolly, C. N. & Sutherland, C., 26 Nov 2004, In : Journal of Biological Chemistry. 279, 48, p. 50176-50180 5 p.

Research output: Contribution to journalArticle

Semaphorin-3A
Glycogen Synthase Kinase 3
Phosphorylation
Neurons
Axons

Protein trafficking in neurons

Connolly, C., 2004, Molecular biology of the neuron. Davies, W. & Morris, B. (eds.). 2nd edition ed. Oxford: Oxford University Press, p. 75 102 p. (Molecular and Cellular Neurobiology Series).

Research output: Chapter in Book/Report/Conference proceedingChapter

140 Citations (Scopus)

The Cys-loop superfamily of ligand-gated ion channels: the impact of receptor structure on function

Connolly, C. N. & Wafford, K. A., Jun 2004, In : Biochemical Society Transactions. 32, 3, p. 529-534 6 p.

Research output: Contribution to journalArticle

The Cys-loop superfamily of ligand-gated ion channels: the impact of receptor structure on function

Connolly, C. N. & Wafford, K. A., 2004.

Research output: Contribution to conferencePaper

2003
41 Citations (Scopus)

Cell surface expression of 5-hydroxytryptamine type 3 receptors is controlled by an endoplasmic reticulum retention signal

Boyd, G. W., Doward, A. I., Kirkness, E. F., Millar, N. S. & Connolly, C. N., 25 Jul 2003, In : Journal of Biological Chemistry. 278, 30, p. 27681-27687 7 p.

Research output: Contribution to journalArticle

Receptors, Serotonin, 5-HT3
Endoplasmic Reticulum
Serotonin
COS Cells
44 Citations (Scopus)

GABAA receptor composition is determined by distinct assembly signals within α and β subunits

Bollan, K., King, D., Robertson, L. A., Brown, K., Taylor, P. M., Moss, S. J. & Connolly, C. N., 2003, In : Journal of Biological Chemistry. 278, 7, p. 4747-4755 9 p.

Research output: Contribution to journalArticle

Multiple assembly signals in g-aminobutyric acid (type A) receptor subunits combine to drive receptor construction and composition

Bollan, K., Robertson, L. A., Tang, H. & Connolly, C. N., 2003.

Research output: Contribution to conferencePaper

32 Citations (Scopus)

Multiple assembly signals in g-aminobutyric acid (type A) receptor subunits combine to drive receptor construction and composition

Bollan, K., Robertson, L. A., Tang, H. & Connolly, C. N., 2003, In : Biochemical Society Transactions. 31, 4, p. 875-879 5 p.

Research output: Contribution to journalArticle

2002
62 Citations (Scopus)

Assembly and cell surface expression of homomeric and heteromeric 5-HT3 receptors: the role of oligomerization and chaperone proteins

Boyd, G. W., Low, P., Dunlop, J. I., Robertson, L. A., Vardy, A., Lambert, J. J., Peters, J. A. & Connolly, C. N., 2002, In : Molecular and Cellular Neuroscience. 21, 1, p. 38-50 13 p.

Research output: Contribution to journalArticle

Receptors, Serotonin, 5-HT3
Endoplasmic Reticulum
Proteins
Cell Surface Receptors
Serotonin
2000
65 Citations (Scopus)

Analysis of GABAA receptor assembly in mammalian cell lines and hippocampal neurons using γ2 subunit green fluorescent protein chimeras

Kittler, J. T., Wang, J., Connolly, C. N., Vicini, S., Smart, T. G. & Moss, S. J., 2000, In : Molecular and Cellular Neuroscience. 16, 4, p. 440-452 13 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Identification of residues within GABAA receptor subunits that mediate specific assembly with receptor β subunits

Taylor, P. M., Connolly, C. N., Kittler, J. T., Gorrie, G. H., Hosie, A., Smart, T. G. & Moss, S. J., 2000, In : Journal of Neuroscience. 20, 4, p. 1297-1306 10 p.

Research output: Contribution to journalArticle

1999
157 Citations (Scopus)

Cell surface stability of gamma-aminobutyric acid type A receptors: dependence on protein kinase C activity and subunit composition

Connolly, C. N., Kittler, J. T., Thomas, P., Uren, J. M., Brandon, N. J., Smart, T. G. & Moss, S. J., 17 Dec 1999, In : Journal of Biological Chemistry. 274, 51, p. 36565-36572 8 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

Identification of amino acid residues within GABA(A) receptor beta subunits that mediate both homomeric and heteromeric receptor expression

Taylor, P. M., Thomas, P., Gorrie, G. H., Connolly, C. N., Smart, T. G. & Moss, S. J., 1 Aug 1999, In : Journal of Neuroscience. 19, 15, p. 6360-6371 12 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Modulation of neuronal and recombinant GABAA receptors by redox reagents

Amato, A., Connolly, C. N., Moss, S. J. & Smart, T. G., 1999, In : Journal of Physiology. 517, 1, p. 35-50 16 p.

Research output: Contribution to journalArticle