• 2834 Citations
  • 30 h-Index
19952017

Research output per year

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Research Output

2017

Environmental Pharmacology: how safe is our chemical jungle?

Connolly, C., 20 Oct 2017, 1 p. London : Biochemical Society.

Research output: Other contribution

Open Access

Honeybee colony losses and threats in Scotland. (2012-2017)

Connolly, C. & Durkacz, J., 6 Oct 2017, 9 p. United Kindgom : University of Dundee.

Research output: Other contribution

Open Access
File
1005 Downloads (Pure)

Nerve agents in honey: Analysis of local honey samples shows global landscape contamination by pesticides

Connolly, C., 6 Oct 2017, In : Science. 358, 6359, p. 38-39 2 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
123 Downloads (Pure)

Subcallosal cingulate deep brain stimulation for treatment-resistant depression: a multi-site, randomized, sham-controlled trial

Holtzheimer, P., Husain, M. M., Lisanby, S. H., Taylor, S. F., Whitworth, L. A., McClintock, S., Slavin, K. V., Berman, J., McKhann, G. M., Patil, P. G., Rittberg, B. R., Abosch, A., Pandurangi, A. K., Holloway, K. L., Lam, R. W., Connolly, C., Neimat, J. S., Henderson, J. M., DeBattista, C., Rothschild, A. J. & 10 others, Pilitsis, J. G., Espinoza, R. T., Petrides, G., Mogilner, A. Y., Matthews, K., Peichel, D., Grosse, R., Hamani, C., Lozano, A. M. & Mayberg, H. S., Nov 2017, In : Lancet Psychiatry. 4, 11, p. 839-849 11 p.

Research output: Contribution to journalArticle

Open Access
File
125 Citations (Scopus)
835 Downloads (Pure)
2016

Neonicotinoids target distinct nicotinic acetylcholine receptors and neurons, leading to differential risks to bumblebees

Moffat, C., Buckland, S. T., Samson, A., McArthur, R., Chamosa Pino, V., Bollan, K. A., Huang, J. T-J. & Connolly, C., 28 Apr 2016, In : Scientific Reports. 6, p. 1-10 10 p., 24764.

Research output: Contribution to journalArticle

Open Access
File
39 Citations (Scopus)
228 Downloads (Pure)

Neuronal networks provide rapid neuroprotection against spreading toxicity

Samson, A. J., Robertson, G., Zagnoni, M. & Connolly, C. N., 21 Sep 2016, In : Scientific Reports. 6, p. 1-11 11 p., 33746.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
167 Downloads (Pure)
2015

Chronic exposure to neonicotinoids increases neuronal vulnerability to mitochondrial dysfunction in the bumblebee (Bombus terrestris)

Moffat, C., Pacheco, J. G., Sharp, S., Samson, A. J., Bollan, K. A., Huang, J., Buckland, S. T. & Connolly, C. N., May 2015, In : FASEB Journal. 29, 5, p. 2112-2119 8 p.

Research output: Contribution to journalArticle

Open Access
File
47 Citations (Scopus)
268 Downloads (Pure)
2014

5-hydroxytryptamine (5-HT) cellular sequestration during chronic exposure delays 5-HT3 receptor resensitization due to Its subsequent release

Hothersall, J. D., Alexander, A., Samson, A. J., Moffat, C., Bollan, K. A. & Connolly, C. N., 14 Nov 2014, In : Journal of Biological Chemistry. 289, 46, p. 32020-32029 10 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
133 Downloads (Pure)
2013

Cholinergic pesticides cause mushroom body neuronal inactivation in honeybees

Palmer, M. J., Moffat, C., Saranzewa, N., Harvey, J., Wright, G. A. & Connolly, C. N., 27 Mar 2013, In : Nature Communications. 4, 1634.

Research output: Contribution to journalArticle

Open Access
124 Citations (Scopus)

Exposure to acetylcholinesterase inhibitors alters the physiology and motor function of honeybees

Williamson, S. M., Moffat, C., Gomersall, M. A. E., Saranzewa, N., Connolly, C. N. & Wright, G. A., 5 Feb 2013, In : Frontiers in Physiology. 4, 13.

Research output: Contribution to journalArticle

Open Access
File
44 Citations (Scopus)
211 Downloads (Pure)

Prolonged inhibition of 5-HT3 receptors by palonosetron results from surface receptor inhibition rather than inducing receptor internalization

Hothersall, J. D., Moffat, C. & Connolly, C. N., Jul 2013, In : British Journal of Pharmacology. 169, 6, p. 1252-1262 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The microsporidian parasites Nosema ceranae and Nosema apis are widespread in honeybee (Apis mellifera) colonies across Scotland

Bollan, K. A., Hothersall, J. D., Moffat, C., Durkacz, J., Saranzewa, N., Wright, G. A., Raine, N. E., Highet, F. & Connolly, C. N., Feb 2013, In : Parasitology Research. 112, 2, p. 751-759 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

The risk of insecticides to pollinating insects

Connolly, C. N., Sep 2013, In : Communicative & Integrative Biology. 6, 5, 3 p., e25074.

Research output: Contribution to journalArticle

2012

A new approach to authorship: shared responsibility and shared credit

Connolly, C. N., Dec 2012, In : Journal of the Royal Society of Medicine. 105, 12, p. 501-502 2 p.

Research output: Contribution to journalLetter

High-affinity fluorescent ligands for the 5-HT3 receptor

Simonin, J., Vernekar, S. K. V., Thompson, A. J., Hothersall, J. D., Connolly, C. N., Lummis, S. C. R. & Lochner, M., 2012, In : Bioorganic & Medicinal Chemistry Letters. 22, 2, p. 1151-1155 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Identifying key knowledge needs for evidence-based conservation of wild insect pollinators: a collaborative cross-sectoral exercise

Dicks, L. V., Abrahams, A., Atkinson, J., Biesmeijer, J., Bourn, N., Brown, C., Brown, M. J. F., Carvell, C., Connolly, C., Cresswell, J. E., Croft, P., Darvill, B., De Zylva, P., Effingham, P., Fountain, M., Goggin, A., Harding, D., Harding, T., Hartfield, C., Heard, M. S. & 30 others, Heathcote, R., Heaver, D., Holland, J., Howe, M., Hughes, B., Huxley, T., Kunin, W. E., Little, J., Mason, C., Memmott, J., Osborne, J., Pankhurst, T., Paxton, R. J., Pocock, M. J. O., Potts, S. G., Power, E. F., Raine, N. E., Ranelagh, E., Roberts, S., Saunders, R., Smith, K., Smith, R. M., Sutton, P., Tilley, L. A. N., Tinsley, A., Tonhasca, A., Vanbergen, A. J., Webster, S., Wilson, A. & Sutherland, W. J., 2012, In : Insect Conservation and Diversity. 6, 3, p. 435-446 12 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2011

2Bs or not 2Bs: that is the question

Connolly, C. N., 2011, In : Journal of Physiology. 589, 17, p. 4085-4086 2 p.

Research output: Contribution to journalArticle

2010

Impact of the chaperone RIC-3 on the expression of human 5-HT3 receptors: role of 5-HT3 B, C, D and E subunits

Walstab, J., Hammer, C., Lasitschka, F., Connolly, C., Rappold, G., Boenisch, H. & Niesler, B., Mar 2010, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 381, p. 16-16 1 p.

Research output: Contribution to journalBook/Film/Article review

Leptin Regulates AMPA Receptor Trafficking via PTEN Inhibition

Moult, P. R., Cross, A., Santos, S. D., Carvalho, A-L., Lindsay, Y., Connolly, C. N., Irving, A. J., Leslie, N. R. & Harvey, J., 17 Mar 2010, In : Journal of Neuroscience. 30, 11, p. 4088-4101 14 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)

RIC-3 Exclusively Enhances the Surface Expression of Human Homomeric 5-Hydroxytryptamine Type 3A (5-HT(3)A) Receptors Despite Direct Interactions with 5-HT3A, -C, -D, and -E Subunits

Walstab, J., Hammer, C., Lasitschka, F., Möller, D., Connolly, C. N., Rappold, G., Bruess, M., Boenish, H. & Niesler, B., 27 Aug 2010, In : Journal of Biological Chemistry. 285, 35, p. 26956-26965 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2009

Rapid dendritic and axonal responses to neuronal insults

Mizielinska, S. M., Greenwood, S. M., Tummala, H. & Connolly, C. N., Dec 2009, In : Biochemical Society Transactions. 37, p. 1389-1393 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2008

The promiscuous role of the epsilon subunit in GABA(A) receptor biogenesis

Bollan, K. A., Baur, R., Hales, T. G., Sigel, E. & Connolly, C. N., Mar 2008, In : Molecular and Cellular Neuroscience. 37, 3, p. 610-621 12 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Trafficking of 5-HT3 and GABA(A) receptors (Review)

Connolly, C., 2008, In : Molecular Membrane Biology. 25, 4, p. 293-301 9 p.

Research output: Contribution to journalReview article

18 Citations (Scopus)
2007

An essential role for constitutive endocytosis, but not activity, in the axonal targeting of the CB1 cannabinoid receptor

McDonald, N. A., Henstridge, C. M., Connolly, C. N. & Irving, A. J., 2007, In : Molecular Pharmacology. 71, 4, p. 976-984 9 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)

Dendritic and mitochondrial changes during glutamate excitotoxicity

Greenwood, S. M. & Connolly, C. N., Dec 2007, In : Neuropharmacology. 53, 8, p. 891-898 8 p.

Research output: Contribution to journalReview article

88 Citations (Scopus)

Differential subcellular localization of RIC-3 Isoforms and their role in determining 5-HT3 receptor composition

Cheng, A., Bollan, K. A., Greenwood, S. M., Irving, A. J. & Connolly, C. N., 7 Sep 2007, In : Journal of Biological Chemistry. 282, 36, p. 26158-26166 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Generation and functional characterization of fluorescent, N-terminally tagged CB1 receptor chimeras for live-cell imaging

McDonald, N. A., Henstridge, C. M., Connolly, C. N. & Irving, A. J., Jun 2007, In : Molecular and Cellular Neuroscience. 35, 2, p. 237-248 12 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Leptin promotes rapid dynamic changes in hippocampal dendritic morphology

O'Malley, D., MacDonald, N., Mizielinska, S., Connolly, C. N., Irving, A. J. & Harvey, J., Aug 2007, In : Molecular and Cellular Neuroscience. 35, 4, p. 559-572 14 p.

Research output: Contribution to journalArticle

124 Citations (Scopus)

Mitochondrial dysfunction and dendritic beading during neuronal toxicity

Greenwood, S. M., Mizielinska, S. M., Frenguelli, B. G., Harvey, J. & Connolly, C. N., 7 Sep 2007, In : Journal of Biological Chemistry. 282, 36, p. 26235-26244 10 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Naturally occurring variations in the human 5-HT3A gene profoundly impact 5-HT3 receptor function and expression

Krzywkowski, K., Jensen, A. A., Connolly, C. N. & Brauner-Osborne, H., Apr 2007, In : Pharmacogenetics and Genomics. 17, 4, p. 255-266 12 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2006

An asymmetric contribution to gamma-aminobutyric type a receptor function of a conserved lysine within TM2-3 of alpha 1, beta 2, and gamma 2 subunits

Hales, T. G., Deeb, T. Z., Tang, H., Bollan, K. A., King, D. P., Johnson, S. J. & Connolly, C. N., 23 Jun 2006, In : Journal of Biological Chemistry. 281, 25, p. 17034-17043 10 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

The role of GABAA receptor biogenesis, structure and function in epilepsy

Mizielinska, S., Greenwood, S. & Connolly, C. N., 2006.

Research output: Contribution to conferencePaper

The role of GABAA receptor biogenesis, structure and function in epilepsy

Mizielinska, S., Greenwood, S. & Connolly, C. N., 2006, In : Biochemical Society Transactions. 34, 5, p. 863-867 5 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2005

Cell surface expression of 5-hydroxytryptamine type 3 receptors is promoted by RIC-3

Cheng, A., McDonald, N. A. & Connolly, C. N., 10 Jun 2005, In : Journal of Biological Chemistry. 280, 23, p. 22502-22507 6 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Cellular and subcellular calcium accumulation during glutamate-induced injury in cerebellar granule neurons

Ward, M. W., Kushnareva, Y., Greenwood, S. & Connolly, C. N., 2005, In : Journal of Neurochemistry. 92, 5, p. 1081-1090 10 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

The epilepsy mutation, γ2(R43Q) disrupts a highly conserved inter-subunit contact site, perturbing the biogenesis of GABAA receptors

Hales, T. G., Tang, H., Bollan, K. A., Johnson, S. J., King, D. P., McDonald, N. A., Cheng, A. & Connolly, C. N., 2005, In : Molecular and Cellular Neuroscience. 29, 1, p. 120-127 8 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)
2004

GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons

Cole, A. R., Knebel, A., Morrice, N. A., Robertson, L. A., Irving, A. J., Connolly, C. N. & Sutherland, C., 26 Nov 2004, In : Journal of Biological Chemistry. 279, 48, p. 50176-50180 5 p.

Research output: Contribution to journalArticle

199 Citations (Scopus)

Protein trafficking in neurons

Connolly, C., 2004, Molecular biology of the neuron. Davies, W. & Morris, B. (eds.). 2nd edition ed. Oxford: Oxford University Press, p. 75 102 p. (Molecular and Cellular Neurobiology Series).

Research output: Chapter in Book/Report/Conference proceedingChapter

The Cys-loop superfamily of ligand-gated ion channels: the impact of receptor structure on function

Connolly, C. N. & Wafford, K. A., 2004.

Research output: Contribution to conferencePaper

The Cys-loop superfamily of ligand-gated ion channels: the impact of receptor structure on function

Connolly, C. N. & Wafford, K. A., Jun 2004, In : Biochemical Society Transactions. 32, 3, p. 529-534 6 p.

Research output: Contribution to journalArticle

144 Citations (Scopus)
2003

Cell surface expression of 5-hydroxytryptamine type 3 receptors is controlled by an endoplasmic reticulum retention signal

Boyd, G. W., Doward, A. I., Kirkness, E. F., Millar, N. S. & Connolly, C. N., 25 Jul 2003, In : Journal of Biological Chemistry. 278, 30, p. 27681-27687 7 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

GABAA receptor composition is determined by distinct assembly signals within α and β subunits

Bollan, K., King, D., Robertson, L. A., Brown, K., Taylor, P. M., Moss, S. J. & Connolly, C. N., 2003, In : Journal of Biological Chemistry. 278, 7, p. 4747-4755 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Multiple assembly signals in g-aminobutyric acid (type A) receptor subunits combine to drive receptor construction and composition

Bollan, K., Robertson, L. A., Tang, H. & Connolly, C. N., 2003.

Research output: Contribution to conferencePaper

Multiple assembly signals in g-aminobutyric acid (type A) receptor subunits combine to drive receptor construction and composition

Bollan, K., Robertson, L. A., Tang, H. & Connolly, C. N., 2003, In : Biochemical Society Transactions. 31, 4, p. 875-879 5 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2002

Assembly and cell surface expression of homomeric and heteromeric 5-HT3 receptors: the role of oligomerization and chaperone proteins

Boyd, G. W., Low, P., Dunlop, J. I., Robertson, L. A., Vardy, A., Lambert, J. J., Peters, J. A. & Connolly, C. N., 2002, In : Molecular and Cellular Neuroscience. 21, 1, p. 38-50 13 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)
2000

Analysis of GABAA receptor assembly in mammalian cell lines and hippocampal neurons using γ2 subunit green fluorescent protein chimeras

Kittler, J. T., Wang, J., Connolly, C. N., Vicini, S., Smart, T. G. & Moss, S. J., 2000, In : Molecular and Cellular Neuroscience. 16, 4, p. 440-452 13 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Identification of residues within GABAA receptor subunits that mediate specific assembly with receptor β subunits

Taylor, P. M., Connolly, C. N., Kittler, J. T., Gorrie, G. H., Hosie, A., Smart, T. G. & Moss, S. J., 2000, In : Journal of Neuroscience. 20, 4, p. 1297-1306 10 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)
1999

Cell surface stability of gamma-aminobutyric acid type A receptors: dependence on protein kinase C activity and subunit composition

Connolly, C. N., Kittler, J. T., Thomas, P., Uren, J. M., Brandon, N. J., Smart, T. G. & Moss, S. J., 17 Dec 1999, In : Journal of Biological Chemistry. 274, 51, p. 36565-36572 8 p.

Research output: Contribution to journalArticle

158 Citations (Scopus)

Identification of amino acid residues within GABA(A) receptor beta subunits that mediate both homomeric and heteromeric receptor expression

Taylor, P. M., Thomas, P., Gorrie, G. H., Connolly, C. N., Smart, T. G. & Moss, S. J., 1 Aug 1999, In : Journal of Neuroscience. 19, 15, p. 6360-6371 12 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

Modulation of neuronal and recombinant GABAA receptors by redox reagents

Amato, A., Connolly, C. N., Moss, S. J. & Smart, T. G., 1999, In : Journal of Physiology. 517, 1, p. 35-50 16 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)