Whitworth, Claire

Dr

  • 3 Citations
  • 1 h-Index
20192019
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  • 29 Similar Profiles
Ubiquitin-Protein Ligases Medicine & Life Sciences
Proteolysis Medicine & Life Sciences
Chromatin Assembly and Disassembly Medicine & Life Sciences
Enzyme kinetics Chemical Compounds
Nucleosomes Medicine & Life Sciences
Neuroglia Medicine & Life Sciences
DNA Repair Medicine & Life Sciences
Ligands Medicine & Life Sciences

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Research Output 2019 2019

  • 3 Citations
  • 1 h-Index
  • 4 Article
1 Citation (Scopus)

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

Farnaby, W., Koegl, M., Roy, M. J., Whitworth, C., Diers, E., Trainor, N., Zollman, D., Steurer, S., Karolyi-Oezguer, J., Riedmueller, C., Gmaschitz, T., Wachter, J., Dank, C., Galant, M., Sharps, B., Rumpel, K., Traxler, E., Gerstberger, T., Schnitzer, R., Petermann, O. & 17 othersGreb, P., Weinstabl, H., Bader, G., Zoephel, A., Weiss-Puxbaum, A., Ehrenhöfer-Wölfer, K., Wöhrle, S., Boehmelt, G., Rinnenthal, J., Arnhof, H., Wiechens, N., Wu, M-Y., Owen-Hughes, T., Ettmayer, P., Pearson, M., McConnell, D. B. & Ciulli, A., Jul 2019, In : Nature Chemical Biology. 15, 7, p. 672-680 9 p.

Research output: Contribution to journalArticle

Proteolysis
Adenosine Triphosphatases
Biophysics
Neoplasms
Chromatin Assembly and Disassembly
41 Downloads (Pure)

Differentiation-Induced Remodelling of Store-Operated Calcium Entry Is Independent of Neuronal or Glial Phenotype but Modulated by Cellular Context

Whitworth, C. L., Redfern, C. P. F. & Cheek, T. R., 1 Feb 2019, In : Molecular Neurobiology. 56, 2, p. 857-872 16 p.

Research output: Contribution to journalArticle

Open Access
File
Neuroglia
Calcium
Phenotype
Neurogenesis
Porins

Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

Farnaby, W., Koegl, M., Roy, M. J., Whitworth, C., Diers, E., Trainor, N., Zollman, D., Steurer, S., Karolyi-oezguer, J., Riedmueller, C., Gmaschitz, T., Wachter, J., Dank, C., Galant, M., Sharps, B., Rumpel, K., Traxler, E., Gerstberger, T., Schnitzer, R., Petermann, O. & 17 othersGreb, P., Weinstabl, H., Bader, G., Zoephel, A., Weiss-puxbaum, A., Ehrenhöfer-wölfer, K., Wöhrle, S., Boehmelt, G., Rinnenthal, J., Arnhof, H., Wiechens, N., Wu, M., Owen-hughes, T., Ettmayer, P., Pearson, M., Mcconnell, D. B. & Ciulli, A., 2 Jul 2019, In : Nature Chemical Biology.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
Ubiquitin-Protein Ligases
Nucleosomes
DNA Repair
Chromatin
2 Citations (Scopus)
68 Downloads (Pure)

SPR-measured dissociation kinetics of PROTAC ternary complexes influence target degradation rate

Roy, M., Winkler, S., Hughes, S. J., Whitworth, C., Galant, M., Farnaby, W., Rumpel, K. & Ciulli, A., 15 Mar 2019, In : ACS Chemical Biology. 14, 3, p. 361-368 8 p.

Research output: Contribution to journalArticle

Open Access
File
Proteolysis
Enzyme kinetics
Degradation
Ubiquitin-Protein Ligases
Assays