Keyphrases
Cytochrome P450 (CYP450)
62%
Cytochrome P450 Reductase
54%
Glutathione S-transferase
48%
Null Mice
44%
Metabolism
39%
Liver
36%
GSTP1
34%
Drug Metabolism
31%
Cytochrome P450 Enzymes
30%
Cytochrome b5
29%
Cytochrome P450 1A1 (CYP1A1)
28%
Hepatic Cytochrome P450
25%
Glutathione S-transferase pi
25%
P450
25%
Nuclear Factor Erythroid 2-related Factor 2 (Nrf2)
22%
Mouse Liver
20%
Humanized
19%
Oxidative Stress
18%
Isoenzymes
17%
Mouse Model
17%
P450s
17%
Constitutive Androstane Receptor
17%
Cytochrome P450 2E1 (CYP2E1)
15%
Knock-in Mouse Model
13%
Cytochrome P450 1A2 (CYP1A2)
13%
Benzo(a)pyrene
12%
Wild Mice
12%
Cytochrome P450 2D6 (CYP2D6)
11%
Detoxification
11%
Pregnane X Receptor
11%
Phenobarbital
11%
Gene Expression
11%
Anticancer Drugs
11%
Reductase
11%
DNA Adducts
11%
DNA Adduct Formation
11%
Environmental Pollutants
10%
Pharmacokinetics
10%
Cytochrome P450 3A4 (CYP3A4)
10%
Species Differences
10%
Reporter Mice
9%
CYP4A1
9%
Nrf2 Transcription Factor
9%
Drug Interactions
9%
Chemopreventive
9%
Drug Disposition
9%
Xenobiotics
9%
Humanized Mouse Model
8%
C-Jun N-terminal Kinase
8%
S-glutathionylation
8%
Pharmacology, Toxicology and Pharmaceutical Science
Cytochrome P450
100%
Knockout Mouse
58%
Cytochrome P450 Reductase
44%
Glutathione
38%
Drug Metabolism
36%
Mouse Model
33%
Glutathione Transferase P1
31%
Transferase
31%
Cytochrome B5
25%
Detoxication
23%
Transcription Factor Nrf2
22%
Isoenzyme
21%
Cytochrome P450 1A1
19%
Carcinogen
18%
Neoplasm
18%
Malignant Neoplasm
17%
Messenger RNA
17%
Constitutive Androstane Receptor
17%
Cytochrome
16%
Pharmacokinetics
16%
Glutathione Transferase
15%
Wild Type Mouse
15%
Unspecific Monooxygenase
14%
Disease
14%
Carcinogenesis
14%
Biological Marker
14%
Anticarcinogen
14%
Xenobiotic Agent
14%
CYP2E1
13%
Reduced Nicotinamide Adenine Dinucleotide Phosphate
13%
Phenobarbital
12%
Benzo(a)pyrene
12%
Antioxidant
11%
CYP1A2
11%
Pregnane X Receptor
11%
Chemopreventive Agents
10%
Paracetamol
10%
Cytochrome P450 4A1
10%
Transgenic Mouse
10%
Oxidoreductase
9%
Reduced Nicotinamide Adenine Dinucleotide (Phosphate) Dehydrogenase (Quinone)
9%
CYP3A4
9%
Aromatic Hydrocarbon Receptor
9%
Hepatotoxicity
8%
CYP2D6
8%
Bioactivation
8%
Drug-Drug Interaction
8%
Phosphotransferase
7%
3 Nitrobenzanthrone
7%
Drug Development
7%