Henderson, Colin

Dr

  • 7006 Citations
  • 40 h-Index
1983 …2021
If you made any changes in Pure these will be visible here soon.

Research Output 1983 2019

Filter
Article
1983
12 Citations (Scopus)

Thyroid status in patients with chronic-renal-failure

Beckett, G. J., Henderson, C. J., Elwes, R., Seth, J. & Lambie, A. T., 1983, In : Clinical Nephrology. 19, 4, p. 172-178 7 p.

Research output: Contribution to journalArticle

1984
2 Citations (Scopus)

Synthesis and characterization of an iodinated bile-salt derivative for photoaffinity-labeling

Henderson, C. J. & Percy-Robb, I. W., 12 Sep 1984, In : Biochimica et Biophysica Acta. Lipids and Lipid Metabolism. 795, 2, p. 257-264 8 p.

Research output: Contribution to journalArticle

1986
5 Citations (Scopus)
1987
31 Citations (Scopus)

Analysis of the biological properties of antibodies raised against intact and deglycosylated porcine zonae pellucidae

Henderson, C. J., Hulme, M. J. & Aitken, R. J., Apr 1987, In : Gamete Research. 16, 4, p. 323-341 19 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Analysis of the surface labelling characteristics of human spermatozoa and the interaction with anti-sperm antibodies

Aitken, R. J., Hulme, M. J., Henderson, C. J., Hargreave, T. B. & Ross, A., Jul 1987, In : Journal of Reproduction and Fertility. 80, 2, p. 473-485 13 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Polyclonal antibodies to a 32-KDA deglycosylated polypeptide from porcine zonae pellucidae will prevent human gamete interaction in vitro

Henderson, C. J., Braude, P. & Aitken, R. J., Nov 1987, In : Gamete Research. 18, 3, p. 251-265 15 p.

Research output: Contribution to journalArticle

1988
29 Citations (Scopus)

Analysis of calmodulin acceptor proteins and the influence of calmodulin antagonists on human spermatozoa

Aitken, R. J., Clarkson, J. S., Hulme, M. J. & Henderson, C. J., Sep 1988, In : Gamete Research. 21, 1, p. 93-111 19 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Contraceptive potential of antibodies to the zona pellucida

Henderson, C. J., Hulme, M. J. & Aitken, R. J., 1 May 1988, In : Journal of Reproduction and Fertility. 83, 1, p. 325-343 19 p.

Research output: Contribution to journalArticle

1990
46 Citations (Scopus)

Testosterone-mediated regulation of mouse renal cytochrome P-450 isoenzymes

Henderson, C., Scott, A. R., Yang, C. S. & Wolf, C. R., 15 Mar 1990, In : Biochemical Journal. 266, 3, p. 675-681 7 p.

Research output: Contribution to journalArticle

1991
40 Citations (Scopus)
1992
221 Citations (Scopus)

Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics

Forrester, L. M., Henderson, C., Glancey, M. J., Back, D. J., Park, B. K., Ball, S. E., Kitteringham, N. R., McLaren, A. W., Miles, J. S., Skett, P. & Wolf, C. R., 15 Jan 1992, In : Biochemical Journal. 281, 2, p. 359-368 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Sexual differentiation and regulation of cytochrome P-450 CYP2C7

Henderson, C. J., Russell, A. L., Allan, J. A. & Wolf, C. R., 9 Jan 1992, In : Biochimica et Biophysica Acta: General Subjects. 1118, 2, p. 99-106 8 p.

Research output: Contribution to journalArticle

1993
38 Citations (Scopus)

1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene, an extremely potent modulator of mouse hepatic cytochrome P-450 gene expression.

Smith, G., Henderson, C. J., WHITE, R., Parker, M. G., Bars, R. G. & Wolf, C. R., 1 Feb 1993, In : Biochemical Journal. 289, 3, p. 807-813 7 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Alterations in rat hepatic drug metabolism during pregnancy and lactation

Borlakoglu, J. T., Scott, A., Henderson, C. J. & Wolf, C. R., 6 Jul 1993, In : Biochemical Pharmacology. 46, 1, p. 29-36 8 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Expression of P450 isoenzymes during rat-liver organogenesis

Borlakoglu, J. T., Scott, A., Henderson, C. J. & Wolf, C. R., Nov 1993, In : International Journal of Biochemistry & Cell Biology. 25, 11, p. 1659-1668 10 p.

Research output: Contribution to journalArticle

138 Citations (Scopus)

High variability of nitrosamine metabolism among individual: role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans

Camus, A-M., Geneste, O., Honkakoski, P., Bereziat, J-C., Henderson, C. J., Wolf, R. C., Bartsch, H. & Lang, M. A., 1993, In : Molecular Carcinogenesis. 7, 4, p. 268-275 8 p.

Research output: Contribution to journalArticle

183 Citations (Scopus)

Identification of P450 enzymes involved in metabolism of verapamil in humans

Kroemer, H. K., Gautier, J. C., Beaune, P., Henderson, C., Roland Wolf, C. & Eichelbaum, M., 1 Sep 1993, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 348, 3, p. 332-337 6 p.

Research output: Contribution to journalArticle

Verapamil
Cytochrome P-450 Enzyme System
Cytochrome P-450 CYP3A
Cytochrome P-450 CYP1A2
Liver
52 Citations (Scopus)

In vitro metabolism of aflatoxin B1 by normal and tumorous liver tissue from Thailand

Kirby, G. M., Wolf, C. R., Neal, G. E., Judah, D. J., Henderson, C. J., Srivatanakul, P. & Wild, C. P., Dec 1993, In : Carcinogenesis. 14, 12, p. 2613-2620 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Transplacental transfer of polychlorinated biphenyls induces simultaneously the expression of P450 isoenzymes and the protooncogenes c-Ha-ras and c-raf

Borlakoglu, J. T., Scott, A., Henderson, C. J., Jenke, H. J. & Wolf, C. R., 6 Apr 1993, In : Biochemical Pharmacology. 45, 7, p. 1373-1386 14 p.

Research output: Contribution to journalArticle

1994
31 Citations (Scopus)
38 Citations (Scopus)

Metabolism of [3-14C] coumarin by human liver microsomes

van Iersel, M. L. P. S., Henderson, C. J., Walters, D. G., Price, R. J., Wolf, C. R. & Lake, B. G., Aug 1994, In : Xenobiotica. 24, 8, p. 795-803 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
1995
16 Citations (Scopus)

Divergent regulation of cytochrome P450 enzymes by morphine and pethidine: a neuroendocrine mechanism?

Rane, A., Liu, Z., Henderson, C. J. & Wolf, C. R., Jan 1995, In : Molecular Pharmacology. 47, 1, p. 57-64 8 p.

Research output: Contribution to journalArticle

1996
15 Citations (Scopus)

Transfer of PCBs via lactation simultaneously induces the expression of P450 isoenzymes and the protooncogenes c-Ha-ras and c-raf in neonates

Borlak, J. T., Scott, A., Henderson, C. J., Jenke, H. J. & Wolf, C. R., 23 Feb 1996, In : Biochemical Pharmacology. 51, 4, p. 517-529 13 p.

Research output: Contribution to journalArticle

1997
100 Citations (Scopus)

A general strategy for the expression of recombinant human cytochrome P450s in Escherichia coli using bacterial signal peptides: expression of CYP3A4, CYP2A6, and CYP2E1

Pritchard, M. P., Ossetian, R., Li, D. N., Henderson, C. J., Burchell, B., Wolf, C. R. & Friedberg, T., 15 Sep 1997, In : Archives of Biochemistry and Biophysics. 345, 2, p. 342-354 13 p.

Research output: Contribution to journalArticle

1998
333 Citations (Scopus)

Increased skin tumorigenesis in mice lacking pi class glutathione S-transferases

Henderson, C. J., Smith, A. G., Ure, J., Brown, K., Bacon, E. J. & Wolf, C. R., 28 Apr 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 9, p. 5275-5280 6 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)

Pi-class glutathione S-transferase: regulation and function

Henderson, C. J., McLaren, A. W., Moffat, G. J., Bacon, E. J. & Wolf, C. R., 24 Apr 1998, In : Chemico-Biological Interactions. 111-112, p. 69-82 14 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Use of transgenic animals in understanding molecular mechanisms of toxicity

Wolf, C. R. & Henderson, C. J., Jun 1998, In : Journal of Pharmacy and Pharmacology. 50, 6, p. 567-574 8 p.

Research output: Contribution to journalArticle

1999
875 Citations (Scopus)

Regulation of JNK signaling by GSTp

Adler, V., Yin, Z., Fuchs, S. Y., Benezra, M., Rosario, L., Tew, K. D., Pincus, M. R., Sardana, M., Henderson, C. J., Wolf, C. R., Davis, R. J. & Ronai, Z., 1 Mar 1999, In : EMBO Journal. 18, 5, p. 1321-1334 14 p.

Research output: Contribution to journalArticle

2000
14 Citations (Scopus)

Cytochrome P450s and chemoprevention

Henderson, C. J., Sahraouei, A. & Wolf, C. R., Feb 2000, In : Biochemical Society Transactions. 28, 2, p. 42-46 5 p.

Research output: Contribution to journalArticle

178 Citations (Scopus)

Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi

Henderson, C. J., Wolf, C. R., Kitteringham, N., Powell, H., Otto, D. & Park, B. K., 7 Nov 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 23, p. 12741-12745 5 p.

Research output: Contribution to journalArticle

2001
146 Citations (Scopus)

Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GST ∏) influences cell proliferation pathways

Ruscoe, J. E., Rosario, L. A., Wang, T., Gate, L., Arifoglu, P., Wolf, C. R., Henderson, C. J., Ronai, Z. & Tew, K. D., 1 Jul 2001, In : Journal of Pharmacology and Experimental Therapeutics. 298, 1, p. 339-345 7 p.

Research output: Contribution to journalArticle

507 Citations (Scopus)
NF-E2-Related Factor 2
Basic-Leucine Zipper Transcription Factors
Glutathione
Small Intestine
Ethoxyquin
2002
306 Citations (Scopus)

Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice

Chanas, S. A., Jiang, Q., McMahon, M., McWalter, G. K., McLellan, L. I., Elcombe, C. R., Henderson, C. J., Wolf, C. R., Moffat, G. J., Itoh, K., Yamamoto, M. & Hayes, J. D., 2002, In : Biochemical Journal. 365, Pt 2, p. 405-16 12 p.

Research output: Contribution to journalArticle

Butylated Hydroxyanisole
Glutathione Transferase
Liver
Transcription Factors
Transferases
2003
145 Citations (Scopus)

Identification of novel roles of the cytochrome P450 system in early embryogenesis: effects on vasculogenesis and retinoic acid homeostasis

Otto, D. M. E., Henderson, C. J., Carrie, D., Davey, M., Gundersen, T. E., Blomhoff, R., Adams, R. H., Tickle, C. & Wolf, C. R., Sep 2003, In : Molecular and Cellular Biology. 23, 17, p. 6103-6116 14 p.

Research output: Contribution to journalArticle

210 Citations (Scopus)

Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase

Henderson, C. J., Otto, D. M. E., Carrie, D., Magnuson, M. A., McLaren, A. W., Rosewell, I. & Wolf, C. R., 2003, In : Journal of Biological Chemistry. 278, 15, p. 13480-13486 7 p.

Research output: Contribution to journalArticle

NADPH-Ferrihemoprotein Reductase
Cytochrome P-450 Enzyme System
Metabolism
Liver
Steroid hormones
114 Citations (Scopus)

Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi

Elsby, R., Kitteringham, N. R., Goldring, C. E., Lovatt, C. A., Chamberlain, M., Henderson, C. J., Wolf, C. R. & Park, B. K., 20 Jun 2003, In : Journal of Biological Chemistry. 278, 25, p. 22243-22249 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Knockout mice in xenobiotic metabolism

Henderson, C. J., Otto, D. M. E., McLaren, A. W., Carrie, D. & Wolf, C. R., 2003, In : Drug Metabolism Reviews. 35, 4, p. 385-392 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Precision-cut tissue slices from transgenic mice as an in vitro toxicology system

Catania, J. M., Parrish, A. R., Kirkpatrick, D. S., Chitkara, M., Bowden, G. T., Henderson, C. J., Wolf, C. R., Clark, A. J., Brendel, K., Fisher, R. L. & Gandolfi, A. J., 2003, In : Toxicology in Vitro. 17, 2, p. 201-205 5 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Protein expression profiling of glutathione S-transferase pi null mice as a strategy to identify potential markers of resistance to paracetamol-induced toxicity in the liver

Kitteringham, N. R., Powell, H., Hamlett, J., Hamlett, J., Lovatt, C., Elsby, R., Henderson, C. J., Wolf, C. R., Pennington, S. R. & Park, B. K., Feb 2003, In : Proteomics. 3, 2, p. 191-207 17 p.

Research output: Contribution to journalArticle

2004
157 Citations (Scopus)

Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates

McWalter, G. K., Higgins, L. G., McLellan, L. I., Henderson, C. J., Song, L., Thornalley, P. J., Itoh, K., Yamamoto, M. & Hayes, J. D., 1 Dec 2004, In : Journal of Nutrition. 134, 12, p. 3499S-3506S

Research output: Contribution to journalArticle

Isothiocyanates
Glutamate-Cysteine Ligase
Brassica
Glutathione Transferase
NAD
2005
105 Citations (Scopus)

Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H: quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols

Arlt, V. M., Stiborova, M., Henderson, C. J., Osborne, M. R., Bieler, C. A., Frei, E., Martinek, V., Sopko, B., Wolf, C. R., Schmeiser, H. H. & Phillips, D. H., 1 Apr 2005, In : Cancer Research. 65, 7, p. 2644-2652 9 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Relationship between hepatic phenotype and changes in gene expression in cytochrome P450 reductase (POR) null mice

Wang, X. J., Chamberlain, M., Vassieva, O., Henderson, C. J. & Wolf, C. R., 15 Jun 2005, In : Biochemical Journal. 388, 3, p. 857-867 11 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

Role of hepatic cytochrome P450s in the pharmacokinetics and toxicity of cyclophosphamide: studies with the hepatic cytochrome P450 reductase null mouse

Pass, G. J., Carrie, D., Boylan, M., Lorimore, S., Wright, E., Houston, B., Henderson, C. J. & Wolf, C. R., 15 May 2005, In : Cancer Research. 65, 10, p. 4211-4217 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

The murine Cyp1a1 gene is expressed in a restricted spatial and temporal pattern during embryonic development

Campbell, S. J., Henderson, C. J., Anthony, D. C., Davidson, D., Clark, A. J. & Wolf, C. R., 18 Feb 2005, In : Journal of Biological Chemistry. 280, 7, p. 5828-5835 8 p.

Research output: Contribution to journalArticle

2006
54 Citations (Scopus)

Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases

Arlt, V. M., Henderson, C. J., Wolf, C. R., Schmeiser, H. H., Phillips, D. H. & Stiborova, M., 28 Mar 2006, In : Cancer Letters. 234, 2, p. 220-231 12 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver

Mutch, D. M., Crespy, V., Clough, J., Henderson, C. J., Lariani, S., Mansourian, R., Moulin, J., Wolf, C. R. & Williamson, G., Jul 2006, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 291, 1, p. G63-G72 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

The hepatic cytochrome P450 reductase null mouse as a tool to identify a successful candidate entity

Henderson, C. J., Pass, G. J. & Wolf, C. R., 15 Mar 2006, In : Toxicology Letters. 162, 1, p. 111-117 7 p.

Research output: Contribution to journalArticle