Colin Palmer

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Palmer, Colin

Professor, Associate Dean for Research

 https://orcid.org/0000-0002-6415-6560
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1987 …2025

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  • 2017

    A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers

    Meng, W., Veluchamy, A., Hebert, H. L., Campbell, A., Colhoun, H. M. & Palmer, C. N. A., 27 Nov 2017, In: British Journal of Dermatology. 177, 6, p. 1664-1670 7 p.

    Research output: Contribution to journal › Article › peer-review

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  • A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

    Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J. & Im, H. K. & 242 others, Teslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimäki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., DePristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., Hrabé de Angelis, M., Maguire, J., Neale, B. M., Poplin, R., Purcell, S., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., Varga, T. V., Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Fowler, S. P., Arya, R., DeFronzo, R. A., Abboud, H. E., Syvänen, A.-C., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Mägi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Müller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S.-T., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J.-Y., Han, B.-G., Käräjämäki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., Melander, O., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., Liu, J., Khor, C.-C., Chia, K. S., Lim, W. Y., Cheng, C.-Y., Chan, E., Tai, E. S., Aung, T., Linneberg, A., Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Kravic, J., Jørgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Owen, K. R., Farmer, A. J., Frayling, T. M., O'Rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stančáková, A., Barroso, I., Bharadwaj, D., Chan, J., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Kesaniemi, Y. A., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jørgensen, T., Hansen, T., Pedersen, O., Kuusisto, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. (Lead / Corresponding author) & Lindgren, C. M. (Lead / Corresponding author), Jul 2017, In: Diabetes. 66, 7, p. 2019-2032 14 p.

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    43 Citations (Scopus)
    189 Downloads (Pure)

  • An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

    Scott, R. A., Scott, L. J., Maegi, R., Marullo, L., Gaulton, K. J., Kaakinen, M., Pervjakova, N., Pers, T. H., Johnson, A. D., Eicher, J. D., Jackson, A. U., Ferreira, T., Lee, Y., Ma, C., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Van Zuydam, N. R., Mahajan, A. & Chen, H. & 31 others, Almgren, P., Voight, B. F., Grallert, H., Mueller-Nurasyid, M., Ried, J. S., Rayner, N. W., Robertson, N., Karssen, L. C., Van Leeuwen, E. M., Willems, S. M., Fuchsberger, C., Kwan, P., Teslovich, T. M., Chanda, P., Li, M., Lu, Y., Dina, C., Thuillier, D., Yengo, L., Jiang, L., Sparso, T., Kestler, H. A., Chheda, H., Eisele, L., Gustafsson, S., Franberg, M., Strawbridge, R. J., Benediktsson, R., Morris, A. D., Palmer, C. N. A. & for the DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Nov 2017, In: Diabetes. 66, 11, p. 2888-2902 15 p.

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    511 Citations (Scopus)
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  • CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia

    Siddiqui, M. K., Veluchamy, A., Maroteau, C., Tavendale, R., Carr, F., Pearson, E., Colhoun, H., Morris, A. D., George, J., Doney, A., Pirmohamed, M., Alfirevic, A., Wadelius, M., Maitland-van der Zee, A. H., Ridker, P. M., Chasman, D. I., Palmer, C. N. A. (Lead / Corresponding author) & PREDICTION-ADR Consortium, Aug 2017, In: Circulation: Cardiovascular Genetics. 10, 4, e001737 .

    Research output: Contribution to journal › Article › peer-review

    4 Citations (Scopus)

  • Cohort Profile: Scottish Diabetes Research Network Type 1 Bioresource Study (SDRNT1BIO)

    Akbar, T., McGurnaghan, S., Palmer, C. N. A., Livingstone, S. J., Petrie, J. R., Chalmers, J., Lindsay, R. S., McKnight, J. A., Pearson, D. W. M., Patrick, A. W., Walker, J., Looker, H. C. & Colhoun, H. M. (Lead / Corresponding author), Jun 2017, In: International Journal of Epidemiology. 46, 3, p. 796-796i 10 p.

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    17 Citations (Scopus)
    313 Downloads (Pure)

  • Cohort profile: The Scottish Research Register SHARE: A register of people interested in research participation linked to NHS datasets

    McKinstry, B., Sullivan, F. M., Vasishta, S., Armstrong, R., Hanley, J., Haughney, J., Philip, S., Smith, B. H., Wood, A. & Palmer, C. N. A. (Lead / Corresponding author), 1 Feb 2017, In: BMJ Open. 7, 2, p. 1-8 8 p., e013351.

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    42 Citations (Scopus)
    213 Downloads (Pure)

  • Discovery of novel heart rate-associated loci using the Exome Chip

    van den Berg, M. E., Warren, H. R., Cabrera, C. P., Verweij, N., Mifsud, B., Haessler, J., Bihlmeyer, N. A., Fu, Y.-P., Weiss, S., Lin, H. J., Grarup, N., Li-Gao, R., Pistis, G., Shah, N., Brody, J. A., Müller-Nurasyid, M., Lin, H., Mei, H., Smith, A. V. & Lyytikäinen, L.-P. & 101 others, Hall, L. M., van Setten, J., Trompet, S., Prins, B. P., Isaacs, A., Radmanesh, F., Marten, J., Entwistle, A., Kors, J. A., Silva, C. T., Alonso, A., Bis, J. C., de Boer, R. A., de Haan, H. G., de Mutsert, R., Dedoussis, G., Dominiczak, A. F., Doney, A. S. F., Ellinor, P. T., Eppinga, R. N., Felix, S. B., Guo, X., Hagemeijer, Y., Hansen, T., Harris, T. B., Heckbert, S. R., Huang, P. L., Hwang, S.-J., Kähönen, M., Kanters, J. K., Kolcic, I., Launer, L. J., Li, M., Yao, J., Linneberg, A., Liu, S., Macfarlane, P. W., Mangino, M., Morris, A. D., Mulas, A., Murray, A. D., Nelson, C. P., Orrú, M., Padmanabhan, S., Peters, A., Porteous, D. J., Poulter, N. R., Psaty, B. M., Qi, L., Raitakari, O. T., Rivadeneira, F., Roselli, C., Rudan, I., Sattar, N., Sever, P., Sinner, M. F., Soliman, E. Z., Spector, T. D., Stanton, A. V., Stirrups, K. E., Taylor, K. D., Tobin, M. D., Uitterlinden, A. G., Vaartjes, I., Hoes, A. W., van der Meer, P., Völker, U., Waldenberger, M., Xie, Z., Zoledziewska, M., Tinker, A., Polasek, O., Rosand, J., Jamshidi, Y., van Duijn, C. M., Zeggini, E., Wouter Jukema, J., Asselbergs, F. W., Samani, N. J., Lehtimäki, T., Gudnason, V., Wilson, J., Lubitz, S. A., Kääb, S., Sotoodehnia, N., Caulfield, M. J., Palmer, C. N. A., Sanna, S., Mook-Kanamori, D. O., Deloukas, P., Pedersen, O., Rotter, J. I., Dörr, M., O'Donnell, C. J., Hayward, C., Arking, D. E., Kooperberg, C., van der Harst, P., Eijgelsheim, M., Stricker, B. H. C. & Munroe, P. B. (Lead / Corresponding author), 15 Jun 2017, In: Human Molecular Genetics. 26, 12, p. 2346-2363 18 p.

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    26 Citations (Scopus)
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  • Early health technology assessments in pharmacogenomics: a case example in cardiovascular drugs

    Geenen, J. W. (Lead / Corresponding author), Baranova, E. V., Asselbergs, F. W., de Boer, A., Vreman, R. A., Palmer, C. N. A., Maitland-van der Zee, A. H., Hövels, A. M. & PREDICTION-ADR Consortium, Aug 2017, In: Pharmacogenomics. 18, 12

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    6 Citations (Scopus)

  • Early life antibiotic use and the risk of asthma and asthma exacerbations in children

    Ahmadizar, F., Vijverberg, S. J. H., Arets, H. G. M., de Boer, A., Turner, S., Devereux, G., Arabkhazaeli, A., Soares, P., Mukhopadhyay, S., Garssen, J., Palmer, C. N. A., de Jongste, J. C., Jaddoe, V. W. V., Duijts, L., van Meel, E. R., Kraneveld, A. D. & Maitland-van der Zee, A. H. (Lead / Corresponding author), Aug 2017, In: Pediatric Allergy and Immunology. 28, 5, p. 430-437 8 p.

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    84 Citations (Scopus)
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  • Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype

    Tragante, V. (Lead / Corresponding author), Gho, J. M. I. H., Felix, J. F., Vasan, R. S., Smith, N. L., Voight, B. F., Palmer, C., van der Harst, P., Moore, J. H., Asselbergs, F. W. & CHARGE Heart Failure Working Group, 26 May 2017, In: BioData Mining. 10, p. 1-11 11 p., 18.

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    5 Citations (Scopus)
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  • Genetic variation in Kruppel like factor 15 is associated with left ventricular hypertrophy in patients with type 2 diabetes: discovery and replication cohorts

    Patel, S. K. (Lead / Corresponding author), Wai, B., Lang, C. C. (Lead / Corresponding author), Levin, D., Palmer, C. N. A., Parry, H. M., Velkoska, E., Harrap, S. B., Srivastava, P. M. & Burrell, L. M. (Lead / Corresponding author), Apr 2017, In: EBioMedicine. 18, p. 171-178 8 p.

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    20 Citations (Scopus)
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  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

    Warren, H. R., Evangelou, E., Cabrera, C. P., Gao, H., Ren, M., Mifsud, B., Ntalla, I., Surendran, P., Liu, C., Cook, J. P., Kraja, A. T., Drenos, F., Loh, M., Verweij, N., Marten, J., Karaman, I., Lepe, M. P. S., O'Reilly, P. F., Knight, J. & Snieder, H. & 37 others, Kato, N., He, J., Tai, E. S., Said, M. A., Porteous, D., Alver, M., Poulter, N., Farrall, M., Gansevoort, R. T., Padmanabhan, S., Mägi, R., Stanton, A., Connell, J., Bakker, S. J. L., Metspalu, A., Shields, D. C., Thom, S., Brown, M., Sever, P., Esko, T., Hayward, C., van der Harst, P., Saleheen, D., Chowdhury, R., Chambers, J. C., Chasman, D. I., Chakravarti, A., The International Consortium of Blood Pressure (ICBP) 1000G Analyses, The CHD Exome+ Consortium, The ExomeBP Consortium, T2D-Genes Consortium, The GoT2DGenes Consortium, The Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium, The International Genomics of Blood Pressure (iGEN-BP) Consortium, The UK Biobank CardioMetabolic Consortium BP working group, Caulfield, M. J. (Lead / Corresponding author) & Elliott, P. (Lead / Corresponding author), Jan 2017, In: Nature Genetics. 49, 3, p. 403-415 16 p.

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    418 Citations (Scopus)
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  • Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk

    Brænne, I., Zeng, L., Willenborg, C., Tragante, V., Kessler, T., Willer, C. J., Laakso, M., Wallentin, L., Franks, P. W., Salomaa, V., Dehghan, A., Meitinger, T., Samani, N. J., Asselbergs, F. W., Erdmann, J. (Lead / Corresponding author), Schunkert, H., Deloukas, P., Kanoni, S., Willenborg, C. & Farrall, M. & 34 others, Assimes, T. L., Thompson, J. R., Ingelsson, E., Saleheen, D., Erdmann, J., Goldstein, B. A., Stirrups, K., König, I. R., Cazier, J.-B., Johansson, Å., Hall, A. S., Lee, J.-Y., Willer, C. J., Chambers, J. C., Esko, T., Folkersen, L., Goel, A., Grundberg, E., Havulinna, A. S., Ho, W. K., Hopewell, J. C., Eriksson, N., Kleber, M. E., Kristiansson, K., Lundmark, P., Lyytikäinen, L.-P., Doney, A. S. F., Morris, A. D., Kim, H. S., Palmer, C. N. A., CARDIoGRAM Consortium, CARDIoGRAMplusC4D Consortium, MuTHER Consortium & Wellcome Trust Case Control Consortium, 22 Aug 2017, In: PLoS ONE. 12, 8, p. 1-19 19 p., e0182999.

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    4 Citations (Scopus)
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  • HLA-Cw6-positive patients with psoriasis show improved response to methotrexate treatment

    West, J., Ogston, S., Berg, J., Palmer, C., Fleming, C., Kumar, V. & Foerster, J. (Lead / Corresponding author), 17 Jul 2017, In: Clinical and Experimental Dermatology. 42, 6, p. 651-655 5 p.

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    37 Citations (Scopus)
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  • Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

    Wheeler, E., Leong, A., Liu, C.-T., Hivert, M.-F., Strawbridge, R. J., Podmore, C., Li, M., Yao, J., Sim, X., Hong, J., Chu, A. Y., Zhang, W., Wang, X., Chen, Y.-P., Maruthur, N. M., Porneala, B. C., Sharp, S. J., Jia, Y., Kabagambe, E. K. & Chang, L.-C. & 31 others, Chen, W.-M., Elks, C. E., Evans, D. S., Fan, Q., Giulianini, F., Go, M. J., Hottenga, J. J., Hu, Y., Jackson, A. U., Kanoni, S., Kim, Y. J., Kleber, M. E., Ladenvall, C., Lecoeur, C., Lim, S.-H., Lu, Y., Mahajan, A., Marzi, C., Nalls, M. A., Navarro, P., Nolte, I. M., Rose, L. M., Rybin, D. V., Sanna, S., Shi, Y., Stram, D. O., Takeuchi, F., Tan, S. P., van der Most, P. J., Palmer, C. N. A. & EPIC-CVD Consortium, EPIC-InterAct Consortium, Lifelines Cohort Study , 12 Sept 2017, In: PLoS Medicine. 14, 9, 30 p., e1002383.

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  • Interaction between variants in the CYP2C9 and POR genes and the risk of sulfonylurea-induced hypoglycaemia: A GoDARTS Study

    Dujic, T., Zhou, K., Donnelly, L. A., Leese, G., Palmer, C. N. A. & Pearson, E. R. (Lead / Corresponding author), 25 Aug 2017, In: Diabetes, Obesity & Metabolism.

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    22 Citations (Scopus)
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  • Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

    Saleheen, D. (Lead / Corresponding author), Zhao, W., Young, R., Nelson, C. P., Ho, W. K., Ferguson, J. F., Rasheed, A., Ou, K., Nurnberg, S. T., Bauer, R. C., Goel, A., Do, R., Stewart, A. F. R., Hartiala, J., Zhang, W., Thorleifsson, G., Strawbridge, R. J., Sinisalo, J., Kanoni, S. & Sedaghat, S. & 31 others, Marouli, E., Kristiansson, K., Zhao, J. H., Scott, R. A., Gauguier, D., Shah, S. H., Smith, A. V., Van Zuydam, N., Cox, A. J., Willenborg, C., Kessler, T., Zeng, L., Province, M. A., Ganna, A., Lind, L., Pedersen, N. L., White, C. C., Joensuu, A., Kleber, M. E., Hall, A. S., März, W., Salomaa, V., O'Donnell, C. J., Ingelsson, E., Feitosa, M. F., Erdmann, J., Bowden, D. W., Palmer, C. N. A., Gudnason, V., de Faire, U. & EPIC-CVD, PROMIS, CARDIoGRAMplusC4D, 13 Jun 2017, In: Circulation. 135, 24, p. 2336-2353 18 p.

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  • Meta-analysis of genome-wide association studies on the intolerance of angiotensin-converting enzyme inhibitors

    Mahmoudpour, S. H., Veluchamy, A., Siddiqui, M. K., Asselbergs, F. W., Souverein, P. C., de Keyser, C. E., Hofman, A., Lang, C. C., Doney, A. S. F., Stricker, B. H., de Boer, A., Maitland-van der Zee, A.-H. (Lead / Corresponding author), Palmer, C. N. A. (Lead / Corresponding author) & PREDICTION-ADR Consortium, Mar 2017, In: Pharmacogenetics and Genomics. 27, 3, p. 112-119 8 p.

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  • New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

    CHD Exome+ Consortium, ExomeBP Consortium, GoT2D Genes Consortium, The UK Biobank CardioMetabolic Consortium BP working group, Kraja, A. T., Cook, J. P., Warren, H. R., Surendran, P., Liu, C., Evangelou, E., Manning, A. K., Grarup, N., Drenos, F., Sim, X., Smith, A. V., Amin, N., Blakemore, A. I. F., Bork-Jensen, J., Brandslund, I. & Farmaki, A.-E. & 36 others, Fava, C., Ferreira, T., Herzig, K.-H., Giri, A., Giulianini, F., Grove, M. L., Guo, X., Harris, S. E., Have, C. T., Havulinna, A. S., Zhang, H., Jørgensen, M. E., Käräjämäki, A. M., Kooperberg, C., Linneberg, A., Little, L., Liu, Y., Bonnycastle, L. L., Lu, Y., Mägi, R., Mahajan, A., Malerba, G., Marioni, R. E., Mei, H., Menni, C., Morrison, A. C., Padmanabhan, S., Palmas, W., Poveda, A., Rauramaa, R., Rayner, N. W., Connell, J. M., Morris, A. P., Palmer, C. N. A., Understanding Society Scientific Group & CHARGE EXOME BP, 13 Oct 2017, In: Circulation: Cardiovascular Genetics. 10, 5, e001778.

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  • Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

    Wain, L. V. (Lead / Corresponding author), Vaez, A., Jansen, R., Joehanes, R., van der Most, P. J., Erzurumluoglu, A. M., O’Reilly, P. F., Cabrera, C. P., Warren, H. R., Rose, L. M., Verwoert, G. C., Hottenga, J. J., Strawbridge, R. J., Esko, T., Arking, D. E., Hwang, S.-J., Guo, X., Kutalik, Z., Trompet, S. & Shrine, N. R. G. & 223 others, Teumer, A., Ried, J. S., Bis, J. C., Smith, A. V., Amin, N., Nolte, I. M., Lyytikäinen, L.-P., Mahajan, A., Wareham, N. J., Hofer, E., Joshi, P. K., Kristiansson, K., Traglia, M., Havulinna, A. S., Goel, A., Nalls, M. A., Sõber, S., Vuckovic, D., Luan, J., Del Greco M., F., Ayers, K. L., Marrugat, J., Ruggiero, D., Lopez, L. M., Niiranen, T., Enroth, S., Jackson, A. U., Nelson, C. P., Huffman, J. E., Zhang, W., Marten, J., Gandin, I., Harris, S. E., Zemunik, T., Lu, Y., Evangelou, E., Shah, N., De Borst, M. H., Mangino, M., Prins, B. P., Campbell, A., Li-Gao, R., Chauhan, G., Oldmeadow, C., Abecasis, G. R., Abedi, M., Barbieri, C. M., Barnes, M. R., Batini, C., Beilby, J. P., Blake, T., Boehnke, M., Bottinger, E. P., Braund, P. S., Brown, M. J., Brumat, M., Campbell, H., Chambers, J. C., Cocca, M., Collins, F. S., Connell, J., Cordell, H. J., Damman, J. J., Davies, G., de Geus, E. J. C., de Mutsert, R., Deelen, J., Demirkale, Y., Doney, A. S. F., Dörr, M., Farrall, M., Ferreira, T., Frånberg, M., Gao, H., Giedraitis, V., Gieger, C., Giulianini, F., Gow, A. J., Hamsten, A., Harris, T. B., Hofman, A., Holliday, E. G., Hui, J., Jarvelin, M.-R., Johansson, Å., Johnson, A. D., Jousilahti, P. R., Jula, A., Kähönen, M., Kathiresan, S., Khaw, K.-T., Kolcic, I., Koskinen, S., Langenberg, C., Larson, M., Launer, L. J., Lehne, B., Liewald, D. C. M., Lin, L.-A., Lind, L., Mach, F., Mamasoula, C., Menni, C., Mifsud, B., Aulchenko, Y., Morgan, A., Morris, A. D., Morrison, A. C., Munson, P. J., Nandakumar, P., Nguyen, Q. T., Nutile, T., Oldehinkel, A. J., Oostra, B. A., Org, E., Padmanabhan, S., Palotie, A., Paré, G., Pattie, A., Penninx, B. W. J. H., Poulter, N. R., Pramstaller, P. P., Raitakari, O. T., Ren, M., Rice, K., Ridker, P. M., Riese, H., Ripatti, S., Robino, A., Rotter, J. I., Rudan, I., Saba, Y., Saint Pierre, A., Sala, C. F., Sarin, A.-P., Schmidt, R., Scott, R. J., Seelen, M. A. J., Shields, D. C., Siscovick, D. S., Sorice, R., Stanton, A., Stott, D. J., Sundström, J., Swertz, M. A., Taylor, K. D., Thom, S., Tzoulaki, I., Tzourio, C., Uitterlinden, A. G., Völker, U., Vollenweider, P., Wild, S. H., Willemsen, G., Wright, A. F., Yao, J., Thériault, S., Conen, D., Attia, J. R., Sever, P., Debette, S., Mook-Kanamori, D. O., Zeggini, E., Spector, T. D., van der Harst, P., Palmer, C. N. A., Vergnaud, A.-C., Loos, R. J. F., Polasek, O., Starr, J. M., Girotto, G., Hayward, C., Kooner, J. S., Lindgren, C. M., Vitart, V., Samani, N. J., Tuomilehto, J., Gyllensten, U. B., Knekt, P., Deary, I. J., Ciullo, M., Elosua, R., Keavney, B. D., Hicks, A. A., Scott, R. A., Gasparini, P., Laan, M., Liu, Y., Watkins, H., Hartman, C. A., Salomaa, V., Toniolo, D., Perola, M., Wilson, J. F., Schmidt, H., Zhao, J. H., Lehtimäki, T., van Duijn, C. M., Gudnason, V., Psaty, B. M., Peters, A., Rettig, R., James, A. L., Jukema, J. W., Strachan, D. P., Palmas, W., Metspalu, A., Ingelsson, E., Boomsma, D. I., Franco, O. H., Bochud, M., Newton-Cheh, C., Munroe, P. B., Elliott, P., Chasman, D. I., Chakravarti, A., Knight, J., Morris, A. P., Levy, D., Tobin, M. D., Snieder, H., Caulfield, M. J. & Ehret, G. B. (Lead / Corresponding author), 24 Jul 2017, In: Hypertension. 70, 3, p. e4-e19 16 p.

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    125 Citations (Scopus)

  • Quantifying the extent to which index event biases influence large genetic association studies

    Yaghootkar, H., Bancks, M. P., Jones, S. E., McDaid, A., Beaumont, R., Donnelly, L., Wood, A. R., Campbell, A., Tyrrell, J., Hocking, L. J., Tuke, M. A., Ruth, K. S., Pearson, E. R., Murray, A., Freathy, R. M., Munroe, P. B., Hayward, C., Palmer, C., Weedon, M. N. & Pankow, J. S. & 2 others, Frayling, T. M. (Lead / Corresponding author) & Kutalik, Z. (Lead / Corresponding author), 1 Jun 2017, In: Human Molecular Genetics. 26, 5, p. 1018-1030 13 p.

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  • Rare and low-frequency coding variants alter human adult height

    CHD Exome+ Consortium, ExomeBP Consortium, T2D-Genes Consortium, GoT2D Genes Consortium, Global Lipids Genetics Consortium, ReproGen Consortium, MAGIC Investigators, Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G. & Justice, A. E. & 41 others, Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T., Locke, A. E., Masca, N. G. D., Ng, M. C. Y., Mudgal, P., Rivas, M. A., Vedantam, S., Mahajan, A., Guo, X., Abecasis, G., Aben, K. K., Adair, L. S., Alam, D. S., Albrecht, E., Allin, K. H., Allison, M., Amouyel, P., Appel, E. V., Arveiler, D., Asselbergs, F. W., Auer, P. L., Balkau, B., Banas, B., Bang, L. E., Benn, M., Bergmann, S., Bielak, L. F., Blüher, M., Boeing, H., Morris, A. D., Palmer, C. N. A., Hirschhorn, J. N. (Lead / Corresponding author), Deloukas, P. (Lead / Corresponding author), Lettre, G. (Lead / Corresponding author) & EPIC-InterAct Consortium, 9 Feb 2017, In: Nature. 542, 7640, p. 186-190 5 p.

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  • Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium

    Farzan, N., Vijverberg, S. J. H., Andiappan, A. K., Arianto, L., Berce, V., Blanca-López, N., Bisgaard, H., Bønnelykke, K., Burchard, E. G., Campo, P., Canino, G., Carleton, B., Celedón, J. C., Chew, F. T., Chiang, W. C., Cloutier, M. M., Daley, D., Den Dekker, H. T., Dijk, N. F. & Duijts, L. & 26 others, Flores, C., Forno, E., Hawcutt, D. B., Hernandez-Pacheco, N., de Jongste, J. C., Kabesch, M., Koppelman, G. H., Manolopoulos, V. G., Melén, E., Mukhopadhyay, S., Nilsson, S., Palmer, C. N., Pino-Yanes, M., Pirmohamed, M., Potočnki, U., Raaijmakers, J. A. M., Repnik, K., Schieck, M., Sio, Y. Y., Smyth, R. L., Szalai, C., Tantisira, K. G., Turner, S., van der Schee, M. P., Verhamme, K. M. & Maitland-van der Zee, A. H. (Lead / Corresponding author), 1 Jul 2017, In: Pharmacogenomics. 18, 10

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    25 Citations (Scopus)

  • Replication confirms the association of loci in FOXE1, PDE8B, CAPZB and PDE10A with thyroid traits: a Genetics of Diabetes Audit and Research Tayside study

    Soto-Pedre, E., Siddiqui, M. K., Doney, A. S., Palmer, C. N. A., Pearson, E. R. & Leese, G. P., 1 Oct 2017, In: Pharmacogenetics and Genomics. 27, 10, p. 356-362 7 p.

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  • Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

    Jason, F. (Lead / Corresponding author), Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E. & Tajes, J. F. & 281 others, Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B.-J., Kim, Y., Kim, Y. J., Kwon, M.-S., Lee, J., Lee, S., Lin, K.-H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B.-G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S.-H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C.-Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C.-C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S.-T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., de Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A.-C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J.-Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Scott, L. J., Morris, A. P., Kang, H. M., Altshuler, D., Burtt, N. P., Florez, J. C., Boehnke, M. & McCarthy, M. I., 19 Dec 2017, In: Scientific Data. 4, p. 1-20 20 p., 170179.

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  • Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

    Webb, T. R., Erdmann, J., Stirrups, K. E., Stitziel, N. O., Masca, N. G. D., Jansen, H., Kanoni, S., Nelson, C. P., Ferrario, P. G., König, I. R., Eicher, J. D., Johnson, A. D., Hamby, S. E., Betsholtz, C., Ruusalepp, A., Franzén, O., Schadt, E. E., Björkegren, J. L. M., Weeke, P. E. & Auer, P. L. & 33 others, Schick, U. M., Lu, Y., Zhang, H., Dube, M.-P., Goel, A., Farrall, M., Peloso, G. M., Won, H.-H., Do, R., van Iperen, E., Kruppa, J., Mahajan, A., Scott, R. A., Willenborg, C., Braund, P. S., van Capelleveen, J. C., Doney, A. S. F., Donnelly, L. A., Asselta, R., Merlini, P. A., Duga, S., Marziliano, N., Denny, J. C., Shaffer, C., El-Mokhtari, N. E., Franke, A., Heilmann, S., Hengstenberg, C., Morris, A. D., Palmer, C. N. A., Wellcome Trust Case Control Consortium, MORGAM Investigators, Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators, Samani, N. J. (Lead / Corresponding author) & Deloukas, P. (Lead / Corresponding author), 21 Feb 2017, In: Journal of the American College of Cardiology. 69, 7, p. 823-836 14 p.

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  • Utility of Population-Level DNA Sequence Data in the Diagnosis of Hereditary Endocrine Disease

    Newey, P. J. (Lead / Corresponding author), Berg, J. N., Zhou, K., Palmer, C. N. A. & Thakker, R. V., 1 Dec 2017, In: Journal of the Endocrine Society. 1, 12, p. 1507-1526 20 p.

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  • Variants in pharmacokinetic transporters and glycemic response to metformin: A metgen meta-analysis

    Dujic, T., Zhou, K., Yee, S. W., van Leeuwen, N., de Keyser, C. E., Javorský, M., Goswami, S., Zaharenko, L., Christiansen, M. M. H., Out, M., Tavendale, R., Kubo, M., Hedderson, M. M., van der Heijden, A. A., Klimčáková, L., Pirags, V., Kooy, A., Brøsen, K., Klovins, J. & Semiz, S. & 6 others, Tkáč, I., Stricker, B. H., Palmer, C. N. A., 't Hart, L. M., Giacomini, K. M. & Pearson, E. R. (Lead / Corresponding author), Jun 2017, In: Clinical Pharmacology & Therapeutics. 101, 6, p. 763-772 10 p.

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  • 2016

    A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough

    Mosley, J. D., Shaffer, C. M., Van Driest, S. L., Weeke, P. E., Wells, Q. S., Karnes, J. H., Velez Edwards, D. R., Wei, W.-Q., Teixeira, P. L., Bastarache, L., Crawford, D. C., Li, R., Manolio, T. A., Bottinger, E. P., McCarty, C. A., Linneman, J. G., Brilliant, M. H., Pacheco, J. A., Thompson, W. & Chisholm, R. L. & 27 others, Jarvik, G. P., Crosslin, D. R., Carrell, D. S., Baldwin, E., Ralston, J., Larson, E. B., Grafton, J., Scrol, A., Jouni, H., Kullo, I. J., Tromp, G., Borthwick, K. M., Kuivaniemi, H., Carey, D. J., Ritchie, M. D., Bradford, Y., Verma, S. S., Chute, C. G., Veluchamy, A., Siddiqui, M., Palmer, C. N. A., Doney, A., MahmoudPour, S. H., Maitland-van der Zee, A. H., Morris, A. D., Denny, J. C. & Roden, D. M. (Lead / Corresponding author), Jun 2016, In: Pharmacogenomics Journal. 16, 3, p. 231-237 7 p.

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  • A Genome-Wide Association Study Provides New Evidence That CACNA1C Gene is Associated With Diabetic Cataract

    Chang, C., Zhang, K., Veluchamy, A., Hébert, H. L., Looker, H. C., Colhoun, H. M., Palmer, C. N. A. & Meng, W. (Lead / Corresponding author), 1 Apr 2016, In: Investigative Ophthalmology & Visual Science. 57, 4, p. 2246-50 5 p.

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  • A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies

    Bodea, C. A., Neale, B. M., Ripke, S., International IBD Genetics Consortium, Daly, M. J., Devlin, B. & Roeder, K. (Lead / Corresponding author), 5 May 2016, In: American Journal of Human Genetics. 98, 5, p. 857-868 12 p.

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    12 Citations (Scopus)

  • Analysis with the exome array identifies multiple new independent variants in lipid loci

    Kanoni, S., Masca, N. G. D., Stirrups, K. E., Varga, T. V., Warren, H. R., Scott, R. A., Southam, L., Zhang, W., Yaghootkar, H., Müller-Nurasyid, M., Couto Alves, A., Strawbridge, R. J., Lataniotis, L., Hashim, N. A., Besse, C., Boland, A., Braund, P. S., Connell, J. M., Dominiczak, A. & Farmaki, A.-E. & 31 others, Franks, S., Grallert, H., Jansson, J.-H., Karaleftheri, M., Keinänen-Kiukaanniemi, S., Matchan, A., Pasko, D., Peters, A., Poulter, N., Rayner, N. W., Renström, F., Rolandsson, O., Sabater-Lleal, M., Sennblad, B., Sever, P., Shields, D., Silveira, A., Stanton, A. V., Strauch, K., Tomaszewski, M., Tsafantakis, E., Waldenberger, M., Blakemore, A. I. F., Dedoussis, G., Escher, S. A., Kooner, J. S., McCarthy, M. I., Palmer, C. N. A., Wellcome Trust Case Control Consortium, Hamsten, A. & Caulfield, M. J., 27 Jul 2016, In: Human Molecular Genetics. 25, 18, p. 4094-4106 13 p.

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  • Childhood asthma exacerbations and the Arg16 β2-receptor polymorphism: A meta-analysis stratified by treatment

    Turner, S. (Lead / Corresponding author), Francis, B., Vijverberg, S., Pino-Yanes, M., Maitland-van der Zee, A. H., Basu, K., Bignell, L., Mukhopadhyay, S., Tavendale, R., Palmer, C., Hawcutt, D., Pirmohamed, M., Burchard, E. G. & Lipworth, B., Jul 2016, In: Journal of Allergy and Clinical Immunology. 138, 1, p. 107-113 7 p.

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  • Childhood obesity in relation to poor asthma control and exacerbation: a meta-analysis

    Ahmadizar, F., Vijverberg, S. J. H., Arets, H. G. M., de Boer, A., Lang, J. E., Kattan, M., Palmer, C. N. A., Mukhopadhyay, S., Turner, S. & Maitland-van der Zee, A. H. (Lead / Corresponding author), 30 Sept 2016, In: European Respiratory Journal. 48, 4, p. 1063-1073 11 p.

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    87 Citations (Scopus)

  • Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease

    Stitziel, N. O. (Lead / Corresponding author), Stirrups, K. E., Masca, N. G. D., Erdmann, J., Ferrario, P. G., König, I. R., Weeke, P. E., Webb, T. R., Auer, P. L., Schick, U. M., Lu, Y., Zhang, H., Dube, M. P., Goel, A., Farrall, M., Peloso, G. M., Won, H. H., Do, R., Van Iperen, E. & Kanoni, S. & 109 others, Kruppa, J., Mahajan, A., Scott, R. A., Willenborg, C., Braund, P. S., Van Capelleveen, J. C., Doney, A. S. F., Donnelly, L. A., Asselta, R., Merlini, P. A., Duga, S., Marziliano, N., Denny, J. C., Shaffer, C. M., El-Mokhtari, N. E., Franke, A., Gottesman, O., Heilmann, S., Hengstenberg, C., Hoffmann, P., Holmen, O. L., Hveem, K., Jansson, J. H., Jöckel, K. H., Kessler, T., Kriebel, J., Laugwitz, K. L., Marouli, E., Martinelli, N., McCarthy, M. I., van Zuydam, N. R., Meisinger, C., Esko, T., Mihailov, E., Escher, S. A., Alver, M., Moebus, S., Morris, A. D., Müller-Nurasyid, M., Nikpay, M., Olivieri, O., Perreault, L. P. L., AlQarawi, A., Robertson, N. R., Akinsanya, K. O., Reilly, D. F., Vogt, T. F., Yin, W., Asselbergs, F. W., Kooperberg, C., Jackson, R. D., Stahl, E., Strauch, K., Varga, T. V., Waldenberger, M., Zeng, L., Kraja, A. T., Liu, C., Ehret, G. B., Newton-Cheh, C., Chasman, D. I., Chowdhury, R., Ferrario, M., Ford, I., Jukema, J. W., Kee, F., Kuulasmaa, K., Nordestgaard, B. G., Perola, M., Saleheen, D., Sattar, N., Surendran, P., Tregouet, D., Young, R., Howson, J. M. M., Butterworth, A. S., Danesh, J., Ardissino, D., Bottinger, E. P., Erbel, R., Franks, P. W., Girelli, D., Hall, A. S., Hovingh, G. K., Kastrati, A., Lieb, W., Meitinger, T., Kraus, W. E., Shah, S. H., McPherson, R., Orho-Melander, M., Melander, O., Metspalu, A., Palmer, C. N. A., Peters, A., Rader, D. J., Reilly, M. P., Loos, R. J. F., Reiner, A. P., Roden, D. M., Tardif, J. C., Thompson, J. R., Wareham, N. J., Watkins, H., Willer, C. J., Kathiresan, S. (Lead / Corresponding author), Deloukas, P. (Lead / Corresponding author), Samani, N. J. (Lead / Corresponding author) & Schunkert, H. (Lead / Corresponding author), 24 Mar 2016, In: New England Journal of Medicine. 374, 12, p. 1134-1144 11 p.

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  • Common Creatine Kinase gene mutation results in falsely reassuring CK levels in muscle disorders

    Wallace, B., Siddiqui, M., Palmer, C. N. A. & George, J. (Lead / Corresponding author), 1 Jun 2016, In: QJM : an International Journal of Medicine. 109, 6, p. 413-414 3 p.

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  • CYP2C8 and SLCO1B1 variants and therapeutic response to thiazolidinediones in patients with type 2 diabetes.

    Dawed, A. Y., Donnelly, L., Tavendale, R., Carr, F., Leese, G., Palmer, C. N. A., Pearson, E. & Zhou, K. (Lead / Corresponding author), Nov 2016, In: Diabetes Care. 39, 11, p. 1902-1908 7 p.

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  • Effect of Serotonin Transporter 5HTTLPR Polymorphism on Gastrointestinal Intolerance to Metformin: A GoDARTS Study

    Dujic, T., Zhou, K., Tavendale, R., Palmer, C. & Pearson, E. (Lead / Corresponding author), 1 Nov 2016, In: Diabetes Care. 39, 11, p. 1896-1901 6 p.

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  • Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12

    Jackson, V. E. (Lead / Corresponding author), Ntalla, I., Sayers, I., Morris, R., Whincup, P., Casas, J.-P., Amuzu, A., Choi, M., Dale, C., Kumari, M., Engmann, J., Kalsheker, N., Chappell, S., Guetta-Baranes, T., McKeever, T. M., Palmer, C. N. A., Tavendale, R., Holloway, J. W., Sayer, A. A. & Dennison, E. M. & 20 others, Cooper, C., Bafadhel, M., Barker, B., Brightling, C., Bolton, C. E., John, M. E., Parker, S. G., Moffat, M. F., Wardlaw, A. J., Connolly, M. J., Porteous, D. J., Smith, B. H., Padmanabhan, S., Hocking, L., Stirrups, K. E., Deloukas, P., Strachan, D. P., Hall, I. P., Tobin, M. D. & Wain, L. V., Jun 2016, In: Thorax. 71, 6, p. 501-509 9 p.

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  • Factors associated with quality of life in children with asthma living in Scotland

    Taminskiene, V., Mukhopadhyay, S., Palmer, C., Mehta, A., Ayres, J., Valiulis, A. & Turner, S. W. (Lead / Corresponding author), May 2016, In: Pediatric Pulmonology. 51, 5, p. 484-490 7 p.

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    9 Citations (Scopus)

  • Genetic evidence for a link between favorable adiposity and lower risk of type 2 diabetes, hypertension and heart disease

    Yaghootkar, H., Lotta, L. A., Tyrrell, J., Smit, R. A. J., Jones, S. E., Donnelly, L., Beaumont, R., Campbell, A., Tuke, M. A., Hayward, C., Ruth, K. S., Padmanabhan, S., Jukema, J. W., Palmer, C. C., Hattersley, A., Freathy, R. M., Langenberg, C., Wareham, N. J., Wood, A. R. & Murray, A. & 5 others, Weedon, M. N., Sattar, N., Pearson, E., Scott, R. A. & Frayling, T. M. (Lead / Corresponding author), Aug 2016, In: Diabetes. 65, 8, p. 2448-2460 13 p.

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  • How can we optimise inhaled beta2 agonist dose as 'reliever' medicine for wheezy pre-school children? Study protocol for a randomised controlled trial

    Mukhopadhyay, S. (Lead / Corresponding author), Seddon, P., Earl, G., Wileman, E., Symes, L., Olden, C., Alberti, C., Bremner, S., Lansley, A., Palmer, C. N. A. & Beydon, N., 11 Nov 2016, In: Trials. 17, p. 1-9 9 p., 541.

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  • Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

    Postmus, I., Warren, H. R., Trompet, S., Arsenault, B. J., Avery, C. L., Bis, J. C., Chasman, D. I., de Keyser, C. E., Deshmukh, H. A., Evans, D. S., Feng, Q., Li, X., Smit, R. A. J., Smith, A. V., Sun, F., Taylor, K. D., Arnold, A. M., Barnes, M. R., Barratt, B. J. & Betteridge, J. & 68 others, Boekholdt, S. M., Boerwinkle, E., Buckley, B. M., Chen, Y.-D. I., de Craen, A. J. M., Cummings, S. R., Denny, J. C., Dubé, M. P., Durrington, P. N., Eiriksdottir, G., Ford, I., Guo, X., Harris, T. B., Heckbert, S. R., Hofman, A., Hovingh, G. K., Kastelein, J. J. P., Launer, L. J., Liu, C.-T., Liu, Y., Lumley, T., McKeigue, P. M., Munroe, P. B., Neil, A., Nickerson, D. A., Nyberg, F., O'Brien, E., O'Donnell, C. J., Post, W., Poulter, N., Vasan, R. S., Rice, K., Rich, S. S., Rivadeneira, F., Sattar, N., Sever, P., Shaw-Hawkins, S., Shields, D. C., Slagboom, P. E., Smith, N. L., Smith, J. D., Sotoodehnia, N., Stanton, A., Stott, D. J., Stricker, B. H., Stürmer, T., Uitterlinden, A. G., Wei, W.-Q., Westendorp, R. G. J., Whitsel, E. A., Wiggins, K. L., Wilke, R. A., Ballantyne, C. M., Colhoun, H. M., Cupples, L. A., Franco, O. H., Gudnason, V., Hitman, G., Palmer, C. N. A., Psaty, B. M., Ridker, P. M., Stafford, J. M., Stein, C. M., Tardif, J.-C., Caulfield, M. J., Jukema, J. W., Rotter, J. I. & Krauss, R. M. (Lead / Corresponding author), Dec 2016, In: Journal of Medical Genetics. 53, 12, p. 835-845 11 p.

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  • Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children

    Rautanen, A., Pirinen, M., Mills, T. C., Rockett, K. A., Strange, A., Ndungu, A. W., Naranbhai, V., Gilchrist, J. J., Bellenguez, C., Freeman, C., Band, G., Bumpstead, S. J., Edkins, S., Giannoulatou, E., Gray, E., Dronov, S., Hunt, S. E., Langford, C., Pearson, R. D. & Su, Z. & 31 others, Vukcevic, D., Macharia, A. W., Uyoga, S., Ndila, C., Mturi, N., Njuguna, P., Mohammed, S., Berkley, J. A., Mwangi, I., Mwarumba, S., Kitsao, B. S., Lowe, B. S., Morpeth, S. C., Khandwalla, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Sawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Deloukas, P. & Kenyan Bacteraemia Study Group, 2 Jun 2016, In: American Journal of Human Genetics. 98, 6, p. 1092-1100 9 p.

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  • The common p.R114W HNF4A mutation causes a distinct clinical subtype of monogenic diabetes

    Laver, T. W., Colclough, K., Shepherd, M., Patel, K., Houghton, J. A. L., Dusatkova, P., Pruhova, S., Morris, A. D., Palmer, C. N., McCarthy, M. I., Ellard, S., Hattersley, A. T. & Weedon, M. N. (Lead / Corresponding author), Oct 2016, In: Diabetes. 65, 10, p. 3212-3217 6 p.

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  • The genetic architecture of type 2 diabetes

    Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & Highland, H. M. & 281 others, Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B.-J., Kim, Y., Kim, Y. J., Kwon, M.-S., Lee, J., Lee, S., Lin, K.-H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B.-G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S.-H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C.-Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C.-C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., van der Schouw, Y. T., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S.-T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., Hrabé de Angelis, M., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A.-C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J.-Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Burtt, N. P., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Florez, J. C., Scott, L. J., Morris, A. P., Kang, H. M., Boehnke, M. (Lead / Corresponding author), Altshuler, D. & McCarthy, M. I. (Lead / Corresponding author), 4 Aug 2016, In: Nature. 536, p. 41-47 29 p., 18642.

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  • The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis

    Robinson, P. C., Leo, P. J., Pointon, J. J., Harris, J., Cremin, K., Bradbury, L. A., Wellcome Trust Case Control Consortium, Australasian Osteoporosis Genetics Consortium AOGC, Stebbings, S., Harrison, A. A., Evans, D. M., Duncan, E. L., Wordsworth, B. P. & Brown, M. A. (Lead / Corresponding author), Jan 2016, In: Genes and Immunity. 17, 1, p. 46-51 6 p.

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    34 Citations (Scopus)

  • The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

    CHARGE-EchoGen Consortium, CHARGE-HF Consortium, Wellcome Trust Case Control Consortium, Ehret, G. B., Ferreira, T., Chasman, D. I., Jackson, A. U., Schmidt, E. M., Johnson, T., Thorleifsson, G., Luan, J., Donnelly, L. A., Kanoni, S., Petersen, A.-K., Pihur, V., Strawbridge, R. J., Shungin, D., Hughes, M. F., Meirelles, O. & Kaakinen, M. & 35 others, Bouatia-Naji, N., Kristiansson, K., Shah, S., Kleber, M. E., Guo, X., Lyytikäinen, L.-P., Fava, C., Eriksson, N., Nolte, I. M., Magnusson, P. K., Salfati, E. L., Rallidis, L. S., Theusch, E., Smith, A. J. P., Folkersen, L., Witkowska, K., Pers, T. H., Joehanes, R., Kim, S. K., Lataniotis, L., Jansen, R., Johnson, A. D., Warren, H., Kim, Y. J., Zhao, W., Wu, Y., Tayo, B. O., Bochud, M., Absher, D., Connell, J. M., Doney, A. S. F., Morris, A. D., Palmer, C. N. A., Newton-Cheh, C. (Lead / Corresponding author) & Munroe, P. B. (Lead / Corresponding author), Oct 2016, In: Nature Genetics. 48, p. 1171-1184 16 p.

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    325 Citations (Scopus)

  • Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

    METASTROKE Consortium, EchoGen Consortium, GIANT Consortium, EPIC-InterAct Consortium, LifeLines Cohort Study, Wellcome Trust Case Control Consortium, Understanding Society Scientific Group, EPIC-CVD Consortium, CHD Exome+ Consortium, T2D-Genes Consortium, GoT2D Genes Consortium, ExomeBP Consortium, The CHD Exome+ Consortium, Generation Scotland, CHARGE-Heart Failure Consortium, Surendran, P., Drenos, F., Young, R., Warren, H. & Cook, J. P. & 47 others, Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A., Harakalova, M., Mihailov, E., Liu, C., Kraja, A. T., Nielsen, S. F., Rasheed, A., Samuel, M., Zhao, W., Bonnycastle, L. L., Jackson, A. U., Narisu, N., Swift, A. J., Southam, L., Marten, J., Huyghe, J. R., Stančáková, A., Fava, C., Ohlsson, T., Matchan, A., Stirrups, K. E., Bork-Jensen, J., Gjesing, A. P., Kontto, J., Perola, M., Shaw-Hawkins, S., Donnelly, L. A., Burgess, S., Connell, J. M., Doney, A. S. F., Morris, A. D., Palmer, C. N. A., Howson, J. M. M. (Lead / Corresponding author) & Munroe, P. B. (Lead / Corresponding author), Oct 2016, In: Nature Genetics. 48, 10, p. 1151-1161 14 p.

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    234 Citations (Scopus)
  • 2015

    A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

    Nikpay, M., Goel, A., Won, H.-H., Hall, L. M., Willenborg, C., Kanoni, S., Saleheen, D., Kyriakou, T., Nelson, C. P., Hopewell, J. C., Webb, T. R., Zeng, L., Dehghan, A., Elver, M., Armasu, S. M., Auro, K., Bjonnes, A., Chasman, D. I., Chen, S. & Ford, I. & 35 others, Franceschini, N., Gieger, C., Grace, C., Gustafsson, S., Huang, J., Hwang, S.-J., Kim, Y. K., Kleber, M. E., Lau, K. W., Lu, X., Lu, Y., Lyytikäinen, L.-P., Mihailov, E., Morrison, A. C., Pervjakova, N., Qu, L., Rose, L. M., Salfati, E., Saxena, R., Scholz, M., Smith, A. V., Tikkanen, E., Uitterlinden, A., Yang, X., Zhang, W., Zhao, W., de Andrade, M., de Vries, P. S., van Zuydam, N. R., Palmer, C. N., for the CARDIoGRAMplusC4D Consortium, Watkins, H. (Lead / Corresponding author), Kathiresan, S. (Lead / Corresponding author), McPherson, R. (Lead / Corresponding author) & Farrall, M. (Lead / Corresponding author), Oct 2015, In: Nature Genetics. 47, 10, p. 1121-1130 10 p.

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