Watts, Colin

Professor

19942018
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Fingerprint Dive into the research topics where Colin Watts is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Dendritic Cells Medicine & Life Sciences
Toll-Like Receptors Medicine & Life Sciences
Cystatins Medicine & Life Sciences
Antigen Presentation Medicine & Life Sciences
asparaginylendopeptidase Medicine & Life Sciences
Antigens Medicine & Life Sciences
cathepsin S Medicine & Life Sciences
Endopeptidases Medicine & Life Sciences

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Projects 2013 2018

Research Output 1994 2018

3 Citations (Scopus)
78 Downloads (Pure)

Asparaginyl endopeptidase (Legumain) supports human Th1 induction via cathepsin L-mediated intracellular C3 activation

Freeley, S., Cardone, J., Günther, S. C., West, E. E., Reinheckel, T., Watts, C., Kemper, C. & Kolev, M. V., 24 Oct 2018, In : Frontiers in Immunology. 9, p. 1-7 7 p., 2449.

Research output: Contribution to journalArticle

Open Access
File
asparaginylendopeptidase
Cathepsin L
T-Lymphocytes
Thymosin
Complement Receptors
3 Citations (Scopus)
71 Downloads (Pure)

Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis

Martinez-Fabregas, J., Prescott, A., van Kasteren, S., Leslie Pedrioli, D., McLean, W., Moles, A., Reinheckel, T., Poli, V. & Watts, C., 17 Dec 2018, In : Nature Communications. 9, 1, p. 1-16 16 p., 5343.

Research output: Contribution to journalArticle

Open Access
File
homeostasis
protease
Oxidative stress
Endopeptidases
Oxidative Stress
13 Citations (Scopus)
22 Downloads (Pure)

PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells

Stathopoulou, C., Gangaplara, A., Mallett, G., Flomerfelt, F. A., Liniany, L. P., Knight, D., Samsel, L. A., Berlinguer-Palmini, R., Yim, J. J., Felizardo, T. C., Eckhaus, M. A., Edgington-Mitchell, L., Martinez-Fabregas, J., Zhu, J., Fowler, D. H., van Kasteren, S. I., Laurence, A., Bogyo, M., Watts, C., Shevach, E. M. & 1 others, Amarnath, S., 21 Aug 2018, In : Immunity. 49, 2, p. 247-263.e7 25 p.

Research output: Contribution to journalArticle

Open Access
File
asparaginylendopeptidase
Death Domain Receptors
Regulatory T-Lymphocytes
Transcription Factors
Down-Regulation
19 Citations (Scopus)
110 Downloads (Pure)

Cystatin F Ensures Eosinophil Survival by Regulating Granule Biogenesis

Matthews, S. P., McMillan, S. J., Colbert, J. D., Lawrence, R. A. & Watts, C., 19 Apr 2016, In : Immunity. 44, 4, p. 795-806 12 p.

Research output: Contribution to journalArticle

Open Access
File
Cystatins
Eosinophils
Brugia malayi
Pathology
Nematode Infections
9 Citations (Scopus)
78 Downloads (Pure)

Structural and functional basis for p38-MK2 activated Rsk signalling in Toll-Like receptor-stimulated dendritic cells

Zaru, R., Edgar, A. J., Hanauer, A. & Watts, C., Jan 2015, In : Molecular and Cellular Biology. 35, 1, p. 132-140 9 p.

Research output: Contribution to journalArticle

Open Access
File
Toll-Like Receptors
Dendritic Cells
Phosphotransferases
Interferon Type I
p38 Mitogen-Activated Protein Kinases