Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 10 Similar Profiles
Chitinases Chemical Compounds
Enzymes Medicine & Life Sciences
Acetylglucosamine Medicine & Life Sciences
Proteins Medicine & Life Sciences
Aspergillus fumigatus Medicine & Life Sciences
Chitin Medicine & Life Sciences
Substrates Chemical Compounds
Catalytic Domain Medicine & Life Sciences

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Research Output 2001 2018

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity

Pao, K-C., Wood, N. T., Knebel, A., Rafie, K., Stanley, M., Mabbitt, P. D., Sundaramoorthy, R., Hofmann, K., van Aalten, D. M. F. & Virdee, S. 11 Apr 2018 In : Nature. 556, p. 381-385 5 p.

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
Esterification
Ubiquitin
Genes
Ubiquitination

Effects of hypo O-GlcNAcylation on Drosophila development

Mariappa, D. N., Ferenbach, A. & van Aalten, D. M. F. 11 May 2018 In : Journal of Biological Chemistry. 293, 19, p. 7209-7221 13 p.

Research output: Contribution to journalArticle

Open Access
File
Clustered Regularly Interspaced Short Palindromic Repeats
Drosophila
Genes
Phenotype
Mediator Complex

Inhibitors against Fungal Cell Wall Remodeling Enzymes

Delso, I., Valero-Gonzalez, J., Gomollón-Bel, F., Castro-López, J., Fang, W., Navratilova, I., van Aalten, D. M. F., Tejero, T., Merino, P. & Hurtado-Guerrero, R. 22 Jan 2018 In : ChemMedChem. 13, 2, p. 128-132 5 p.

Research output: Contribution to journalArticle

Triazoles
Aspergillus fumigatus
Glucans
X Ray Crystallography
Enzyme Inhibitors

O-GlcNAcase Fragment Discovery with Fluorescence Polarimetry

Borodkin, V. S., Rafie, K., Selvan, N., Aristotelous, T., Navratilova, I., Ferenbach, A. T. & Van Aalten, D. M. F. 18 May 2018 In : ACS Chemical Biology. 13, 5, p. 1353-1360 8 p.

Research output: Contribution to journalArticle

Polarimeters
Fluorescence
Assays
Hexosaminidase B
Cardiovascular Diseases

The O-GlcNAc Transferase Intellectual Disability Mutation L254F Distorts the TPR Helix

Gundogdu, M., Llabres, S., Gorelik, A., Ferenbach, A., Zachariae, U. & Van Aalten, D. 21 Jun 2018 In : Cell Chemical Biology. 25, p. 1-6 1 p.

Research output: Contribution to journalArticle

Open Access
File
Intellectual Disability
Mutation
Acetylglucosamine
Post Translational Protein Processing
Brain

Press / Media

'Bacterial raincoat' found to protect bacteria from the environment

Daan Van Aalten & Nicola Stanley-Wall

30/07/131/08/13

3 items of media coverage

Press/Media: Research

Breakthrough in understanding role of enzyme in disease

Daan Van Aalten

29/10/12

1 item of media coverage

Press/Media: Research

Thesis

Biochemical characterisation of the Parkinson's disease-associated kinase PINK1: Insights from the insect world

Author: Woodroof, H. I., 2014

Supervisor: Muqit, M. (Supervisor), Van Aalten, D. (Supervisor) & Alessi, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Function and inhibition of the mitochondrial O-GlcNAc transferase isoform

Author: Trapannone, R., 2015

Supervisor: Van Aalten, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Molecular characterisation of O-GlcNAc transferase

Author: Zheng, X., 2013

Supervisor: Van Aalten, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Reductionist animal models to probe protein O-GlcNAcylation

Author: Selvan, N., 2015

Supervisor: Van Aalten, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Structural and biochemical characterisation of enzymes involved in mannan biosynthesis

Author: Striebeck, A., 2013

Supervisor: Van Aalten, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File