Baptista-Hon, Daniel

Dr

  • 126 Citations
  • 6 h-Index
20122019
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Research Output 2012 2019

  • 126 Citations
  • 6 h-Index
  • 13 Article
2019

Amino acid substitutions in the human homomeric β3 GABAA receptor that enable activation by GABA

Gottschald Chiodi, C., Baptista-Hon, D., Hunter, W. & Hales, T., 15 Feb 2019, In : Journal of Biological Chemistry. 294, 7, p. 2375-2385 11 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Amino Acid Substitution
gamma-Aminobutyric Acid
Substitution reactions
Chemical activation
2018
2 Citations (Scopus)
78 Downloads (Pure)

Menthol reduces phototoxicity pain in a mouse model of photodynamic therapy

Wright, L., Baptista-Hon, D., Bull, F., Dalgaty, F., Gallacher, M., Ibbotson, S. H. & Hales, T. G., 1 Feb 2018, In : Pain. 159, 2, p. 284-297 14 p.

Research output: Contribution to journalArticle

Open Access
File
Menthol
Phototoxic Dermatitis
Photochemotherapy
Action Potentials
Pain
25 Downloads (Pure)
Open Access
File
Lidocaine
Local Anesthetics
Neoplasms
HEK293 Cells
Patch-Clamp Techniques
2017
4 Citations (Scopus)
76 Downloads (Pure)

Loop G in the GABAA receptor α1 subunit influences gating efficacy

Baptista-Hon, D. T., Gulbinaite, S. & Hales, T. G., 1 Mar 2017, In : Journal of Physiology. 595, 5, p. 1725-1741 16 p.

Research output: Contribution to journalArticle

Open Access
File
Propofol
GABA-A Receptors
gamma-Aminobutyric Acid
GABA Receptors
Bicuculline
4 Citations (Scopus)
94 Downloads (Pure)
Open Access
File
Ventral Tegmental Area
mu Opioid Receptor
Morphine
Inhibitory Postsynaptic Potentials
Neurons
2 Citations (Scopus)
66 Downloads (Pure)

Src Kinase Inhibition Attenuates Morphine Tolerance without Affecting Reinforcement or Psychomotor Stimulation

Bull, F. A., Baptista-Hon, D. T., Sneddon, C., Wright, L., Walwyn, W. & Hales, T. G., 1 Nov 2017, In : ANESTHESIOLOGY. 127, 5, p. 878-889 12 p.

Research output: Contribution to journalArticle

Open Access
File
src-Family Kinases
Morphine
Pleasure
Opioid Analgesics
Analgesics
2016
3 Citations (Scopus)
72 Downloads (Pure)

A role for loop G in the β1 strand in GABAA receptor activation

Baptista-Hon, D. T., Krah, A., Zachariae, U. & Hales, T. G., 1 Oct 2016, In : Journal of Physiology. 594, 19, p. 5555-5571 17 p.

Research output: Contribution to journalArticle

Open Access
File
GABA-A Receptors
gamma-Aminobutyric Acid
Propofol
GABA Agonists
GABA Receptors
2015
7 Citations (Scopus)

Agonist- and antagonist-induced up-regulation of surface 5-HT3A receptors

Morton, R. A., Baptista-Hon, D. T., Hales, T. G. & Lovinger, D. M., Aug 2015, In : British Journal of Pharmacology. 172, 16, p. 4066-4077 12 p.

Research output: Contribution to journalArticle

Receptors, Serotonin, 5-HT3
Up-Regulation
Bungarotoxins
Serotonin
Antidepressive Agents
31 Citations (Scopus)
83 Downloads (Pure)

Voltage-gated Na+ channel activity increases colon cancertranscriptional activity and invasion via persistent MAPK signaling

House, C. D., Wang, B. D., Ceniccola, K., Williams, R., Simaan, M., Olender, J., Patel, V., Baptista-Hon, D. T., Annunziata, C. M., Gutkind, J. S., Hales, T. G. & Lee, N. H., 22 Jun 2015, In : Scientific Reports. 5, 16 p., 11541.

Research output: Contribution to journalArticle

Open Access
File
Colon
Colonic Neoplasms
Genes
Gene Knockdown Techniques
Gene Expression
2014
27 Citations (Scopus)

Potent inhibition by ropivacaine of metastatic colon cancer SW620 cell invasion and NaV1.5 channel function

Baptista-Hon, D. T., Robertson, F. M., Robertson, G. B., Owen, S. J., Rogers, G. W., Lydon, E. L., Lee, N. H. & Hales, T. G., Jul 2014, In : British Journal of Anaesthesia. 113 , Suppl. 1, p. i39-i48 10 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Neoplasms
Nociceptors
Perioperative Period
Conduction Anesthesia
2013
19 Citations (Scopus)
Cysteine Loop Ligand-Gated Ion Channel Receptors
Neurotransmitter Receptor
Structural integrity
2012
10 Citations (Scopus)

Influences on blockade by t-butylbicyclo-phosphoro-thionate of GABA(A) receptor spontaneous gating, agonist activation and desensitization

Othman, N. A., Gallacher, M., Deeb, T. Z., Baptista-Hon, D. T., Perry, D. C. & Hales, T. G., 2012, In : Journal of Physiology. 590, 1, p. 163-178 16 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

The 5-HT3B subunit affects high-potency inhibition of 5-HT3 receptors by morphine

Baptista-Hon, D. T., Deeb, T. Z., Othman, N. A., Sharp, D. & Hales, T. G., 2012, In : British Journal of Pharmacology. 165, 3, p. 693-704 12 p.

Research output: Contribution to journalArticle