Fletcher, Daniel

Dr

  • United Kingdom

  • 23 Citations
  • 2 h-Index
20162019
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  • 29 Similar Profiles
Pharmaceutical Preparations Chemical Compounds
Lysosphingolipid Receptors Chemical Compounds
Ubiquitin-Protein Ligases Chemical Compounds
Hydroxyproline Chemical Compounds
Antimalarials Chemical Compounds
Drug Discovery Medicine & Life Sciences
Metabolites Chemical Compounds
Drug Users Medicine & Life Sciences

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Research Output 2016 2019

  • 23 Citations
  • 2 h-Index
  • 7 Article
26 Downloads (Pure)

Characterising Covalent Warhead Reactivity

Martin, J., Mackenzie, C., Fletcher, D. & Gilbert, I., 15 May 2019, In : Bioorganic & Medicinal Chemistry. 27, 10, p. 2066-2076 9 p.

Research output: Contribution to journalArticle

Open Access
File
Toxicity
Pharmaceutical Preparations
Aptitude
Pharmacokinetics
Threonine
29 Downloads (Pure)
Open Access
File
Lysosphingolipid Receptors
Drug Discovery
Modulators
Skin
Pharmaceutical Preparations

Substituted aminoacetamides as novel leads for malaria

Norcross, N., Wilson, C., Baragana, B., Hallyburton, I., Osuna-Cabello, M., Norval, S., Riley, J., Fletcher, D., Sinden, R., Delves, M. J., Ruecker, A., Duffy, S., Meister, S., Antonova-Koch, Y., Crespo, B., de Cózar, C., Sanz, L., Gamo, F-J., Avery, V. M., Frearson, J. A. & 8 othersGray, D., Fairlamb, A., Winzeler, E. A., Waterson, D., Campbell, S. F., Willis, P., Read, K. & Gilbert, I., 12 Jun 2019, In : ChemMedChem. 16 p.

Research output: Contribution to journalArticle

Open Access
File
Antimalarials
Germ Cells
Malaria
Pharmacokinetics
Plasmodium falciparum
9 Citations (Scopus)
35 Downloads (Pure)

3-Fluoro-4-hydroxyprolines: Synthesis, conformational analysis and stereoselective recognition by the VHL E3 ubiquitin ligase for targeted protein degradation

Testa, A., Lucas, X., Castro, G., Chan, K. H., Wright, J., Runcie, A., Gadd, M., Harrison, W. T. A., Ko, E. J., Fletcher, D. & Ciulli, A., 25 Jul 2018, In : Journal of the American Chemical Society. 140, 29, p. 9299-9313 15 p.

Research output: Contribution to journalArticle

Open Access
File
Hydroxyproline
Ubiquitin-Protein Ligases
Proteolysis
Proteins
Degradation
2 Citations (Scopus)
52 Downloads (Pure)
Open Access
File
Metabolites
Drug Users
Metabolism
Opioid Analgesics
Urine