Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- QH301 Biology
- Biochemistry
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Collaborations and top research areas from the last five years
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Mutational screen of GBA1, PARKIN and LRRK2
Alessi, D. (Investigator), Muqit, M. (Investigator) & Sammler, E. (Investigator)
1/08/24 → 31/07/26
Project: Research
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Spatial Proteomics to Study Brain Health and Neurodegeneration
Alessi, D. (Investigator)
1/04/24 → 31/08/27
Project: Research
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Interrogating Tankyrase-mediated Control of Neuronal Degeneration in Frontotemporal Dementia (Dementia Research Leader Fellowship) (Outline) & Full
Alessi, D. (Investigator), Ashford, M. (Investigator), Davies, P. (Investigator), McGurk, L. (Investigator) & Storey, K. (Investigator)
2/10/23 → 1/10/28
Project: Research
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Louis-Jeantet Prize 2023 - Personal Award
Alessi, D. (Investigator)
1/06/23 → 31/05/28
Project: Research
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Shared Proteomics Platform For The MRC PPU And The UK Dementia Research Institute (UK DRI)
Alessi, D. (Investigator)
1/04/23 → 31/03/28
Project: Research
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Clinical and functional evidence for the pathogenicity of the LRRK2 p.Arg1067Gln variant
Lim, S. Y., Toh, T. S., Hor, J. W., Lim, J. L., Lit, L. C., Ahmad-Annuar, A., Tay, Y. W., Foo, J. N., Ng, E. Y., Muthusamy, K. A., Mohamed Ibrahim, N., Ibrahim, K. A., Tan, L. C. S., Zulkefli, J., Khairul Anuar, A. N., Black, K., Lis, P., Xie, F., Cen, Z. & Lim, K. S. & 7 others, , Dec 2025, In: NPJ Parkinson's disease. 11, 1, 9 p., 34.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)6 Downloads (Pure) -
Dundee Research Interest Group Open Doors Day Event Report 2025
Patrick, S., Hardie, G., Hawdon, B., Goodburn, J., Coxe, M., Milne, J., Rigg, D., Sammler, E. (Editor), Howden, A. (Editor), Alessi, D. (Contributing member), Lacey-Solymar, G. (Contributing member) & Nash, L., 28 Feb 2025, Dundee: University of Dundee. 11 p.Research output: Book/Report › Book
Open AccessFile87 Downloads (Pure) -
Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain
Bagnoli, E., Lin, Y.-E., Burel, S., Jaimon, E., Antico, O., Themistokleous, C., Nikoloff, J. M., Squires, S., Morella, I., Watzlawik, J. O., Fiesel, F. C., Springer, W., Tonelli, F., Lis, P., Brooks, S. P., Dunnett, S. B., Brambilla, R., Alessi, D. R., Pfeffer, S. R. & Muqit, M. M. K. (Lead / Corresponding author), 4 Feb 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 5, 12 p., e2412029122.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)30 Downloads (Pure) -
NRBP1 and TSC22D proteins impact distal convoluted tubule physiology through modulation of the WNK pathway
Amnekar, R. & Alessi, D., 3 Jan 2025, BioRxiv, 32 p.Research output: Working paper/Preprint › Preprint
Open Access -
Tagless LysoIP for immunoaffinity enrichment of native lysosomes from clinical samples
Saarela, D., Lis, P., Gomes, S., Nirujogi, R., Dong, W., Rawat, E. S., Glendinning, S., Zeneviciute, K., Bagnoli, E., Fasimoye, R., Lin, C., Nyame, K., Boros, F. A., Zunke, F., Lamoliatte, F., Elshani, S., Jaconelli, M., Jans, J. J. M., Huisman, M. A. & Posern, C. & 6 others, , 17 Feb 2025, In: Journal of Clinical Investigation. 135, 4, 15 p., e183592.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)7 Downloads (Pure)
Datasets
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Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain
Khan, S. (Creator), Sobu, Y. (Creator), Pfeffer, S. (Creator), Dhekne, H. (Creator), Tonelli, F. (Creator), Berndsen, K. (Creator) & Alessi, D. (Creator), Dryad, 1 Nov 2021
DOI: 10.5061/dryad.76hdr7sxx, https://datadryad.org/stash/dataset/doi:10.5061/dryad.76hdr7sxx
Dataset
Prizes
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Jeantet-Collen Prize for Translational Medicine
Alessi, D. (Recipient), 26 Apr 2023
Prize: Prize (including medals and awards)
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Michael J. Fox Foundation - The Robert A. Pritzker Prize for Leadership in Parkinson's Research
Alessi, D. (Recipient), 3 Nov 2023
Prize: Prize (including medals and awards)
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Dundee Research Interest Group Open Doors Day 2025
Alessi, D. (Participant), Sammler, E. (Organiser), Howden, A. (Organiser), Muqit, M. (Participant), Ganley, I. (Participant), Gilbertson, T. (Participant), Farnaby, W. (Participant), Hardie, G. (Participant), Hawdon, B. (Organiser), Goodburn, J. (Organiser), Coxe, M. (Participant), Milne, J. (Participant), Rigg, D. (Participant), Vangheluwe, P. (Participant), Kerr, J. (Participant), Stewart, T. (Participant), Lacey-Solymar, G. (Participant), Patrick, S. (Participant), Nash, L. (Participant), Langlands, A. (Participant), Hirons, Z. (Organiser), Grayson, L. (Contributor), Bishnu, A. (Participant), Wilhelm, L. (Participant), Appleton, P. (Participant), Filipe Soares, R. (Participant), Robertson, J. (Participant), Ibba, R. (Participant), Hallatt, A. (Participant) & Wieske, L. (Participant)
28 Feb 2025Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Invited talk
Alessi, D. (Speaker)
18 Jun 2024 → 21 Jun 2024Activity: Talk or presentation types › Invited talk
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Press release - Dundee team leading groundbreaking cancer and Parkinson’s research given five-year funding boost to continue life-saving work
Alessi, D. (Member)
5 Sept 2024Activity: Other activity types › Public engagement and outreach - media article or participation
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Investigator Meeting
Alessi, D. (Speaker)
2 Mar 2024 → 8 Mar 2024Activity: Talk or presentation types › Oral presentation
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MJFF grant kick-off meeting
Alessi, D. (Member)
3 May 2024 → 4 May 2024Activity: Other activity types › Other
Press/Media
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LRRK2 Investigative Therapeutic Exchange (LITE) project
21/10/24
1 Media contribution
Press/Media: Other
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STV news article about Parkinson's research, public engagement and clinical trials in Dundee
6/02/24
1 Media contribution
Press/Media: Research
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Parkinson's disease hope: 'This is a very exciting time'
15/09/23
1 Media contribution
Press/Media: Research