Projects per year
Personal profile
Keywords
- QH301 Biology
- Biochemistry
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Dive into the research topics where Dario Alessi is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
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ASAP - Mapping the LRRK2 Signalling Pathway and its Interplay with other Parkinson's Disease Components
1/10/20 → 30/09/23
Project: Research
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Research Output
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Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms
Malik, A. U., Karapetsas, A., Nirujogi, R. S., Mathea, S., Chatterjee, D., Pal, P., Lis, P., Taylor, M., Purlyte, E., Gourlay, R., Dorward, M., Weidlich, S., Toth, R., Polinski, N. K., Knapp, S., Tonelli, F. & Alessi, D., 18 Jan 2021, In: Biochemical Journal.Research output: Contribution to journal › Article › peer-review
Open Access -
Development of a multiplexed targeted mass spectrometry assay for LRRK2-phosphorylated Rabs and Ser910/Ser935 biomarker sites
Nirujogi, R. S., Tonelli, F., Taylor, M., Lis, P., Zimprich, A., Sammler, E. & Alessi, D. R., 22 Jan 2021, In: Biochemical Journal. 478, 2, p. 299-326 28 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Accurate MS-based Rab10 phosphorylation stoichiometry determination as readout for LRRK2 activity in Parkinson's disease
Karayel, O., Tonelli, F., Virreira Winter, S., Geyer, P. E., Fan, Y., Sammler, E. M., Alessi, D., Steger, M. & Mann, M., 1 Sep 2020, In: Molecular & Cellular Proteomics. 19, 9, p. 1546-1560 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Advances in elucidating the function of leucine-rich repeat protein kinase-2 in normal cells and Parkinson's disease
Taylor, M. & Alessi, D., Apr 2020, In: Current Opinion in Cell Biology. 63, p. 102-113 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)142 Downloads (Pure) -
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
Gordon, D. E., Hiatt, J., Bouhaddou, M., Rezelj, V. V., Ulferts, S., Braberg, H., Jureka, A. S., Obernier, K., Guo, J. Z., Batra, J., Kaake, R. M., Weckstein, A. R., Owens, T. W., Gupta, M., Pourmal, S., Titus, E. W., Cakir, M., Soucheray, M., McGregor, M., Cakir, Z. & 40 others, , 4 Dec 2020, In: Science (New York, N.Y.). 370, 6521, 28 p., eabe9403.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)16 Downloads (Pure)