Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- QH301 Biology
- Biochemistry
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High-Throughput-Analysis to Identify and Characterize PPM1H Protein Phosphatase Activity Enhancers
1/02/22 → 31/07/23
Project: Research
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MRC Climate Crisis Network (Lead: University Of Dundee other instns: Mitocondrial Unit, Human Genetics Unit)
1/01/22 → 31/12/23
Project: Research
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Identifying PD Biomarkers In Peripheral Blood Immune Cells Using Mass Spectrometry And Single Cell RNA Sequencing
14/09/21 → 13/09/23
Project: Research
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Differential LRRK2 Dependent Rab Phosphorylation Signatures in Peripheral Blood and Urine in Idiopathic and Monogenetic PD
1/06/21 → 31/05/22
Project: Research
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Sequence and structural variations determining the recruitment of WNK kinases to the KLHL3 E3 ligase
Chen, Z., Zhang, J., Murillo-de-Ozores, A. R., Castañeda-Bueno, M., D'Amico, F., Heilig, R., Manning, C., Sorrell, F. J., D'Angiolella, V., Fischer, R., Mulder, M., Gamba, G., Alessi, D. R. & Bullock, A. N., 4 Mar 2022, In: Biochemical Journal. 479, 5, p. 661-675 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Downloads (Pure) -
A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research
Rihn, S. J., Merits, A., Bakshi, S., Turnbull, M. L., Wickenhagen, A., Alexander, A. J. T., Baillie, C., Brennan, B., Brown, F., Brunker, K., Bryden, S. R., Burness, K. A., Carmichael, S., Cole, S. J., Cowton, V. M., Davies, P., Davis, C., De Lorenzo, G., Donald, C. L., Dorward, M. & 62 others, , 25 Feb 2021, In: PLoS Biology. 19, 2, 22 p., e3001091.Research output: Contribution to journal › Article › peer-review
Open AccessFile37 Citations (Scopus)119 Downloads (Pure) -
Characterization of LRP10 Expression in Lewy Body Disorders and AND IPSC-Derived Brain Cells
Grochowska, M., Carreras Mascaro, A., Boumeester, V., Natale, D., Breedveld, G., Geut, H., van Cappellen, W., Boon, A., Kievit, A., Sammler, E., Parchi, P., Cortelli, P., Alessi, D., van de Berg, W., Bonifati, V. & Mandemakers, W., 2021, In: Movement Disorders. 36, Supplement 1, p. S3334 1 p., 781.Research output: Contribution to journal › Meeting abstract › peer-review
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Correlating LRRK2 activation status in peripheral blood to urine BMPs in monogenic and idiopathic Parkinson’s disease
Gomes, S., Garrido, A., Tonelli, F., Tolosa, E., Marti, M., Anderson, D., Pratuseviciute, N., Hsieh, F., Bruecke, T., Koenig, T., Hotzy, C., Ruiz-Martínez, J., Bergareche-Yarza, A., Mondragón Rezola, E., Vinagre Aragón, A., Croitoru, I., Gorostidi Pagola, A., Markinez, L. P., Valldeoriola, F., Merchant, K. M. & 4 others, , 2021, In: Movement Disorders. 36, Supplement 1, p. S333-S334 2 p., 780.Research output: Contribution to journal › Meeting abstract › peer-review
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Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms
Malik, A. U., Karapetsas, A., Nirujogi, R. S., Mathea, S., Chatterjee, D., Pal, P., Lis, P., Taylor, M., Purlyte, E., Gourlay, R., Dorward, M., Weidlich, S., Toth, R., Polinski, N. K., Knapp, S., Tonelli, F. & Alessi, D., 10 Feb 2021, In: Biochemical Journal. 478, 3, p. 553-578 26 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)84 Downloads (Pure)
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Understanding the LRRK2 kinase and its role in Parkinson's Disease
Dario Alessi (Speaker)
14 Dec 2021Activity: Talk or presentation types › Invited talk
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International Union of Biochemistry and Molecular Biology (External organisation)
Dario Alessi (Chair)
2021 → …Activity: Membership types › Membership of group
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Royal Society (External organisation)
Dario Alessi (Chair)
2019 → …Activity: Membership types › Membership of board
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UK Dementia Research Institute (External organisation)
Dario Alessi (Chair)
2019 → …Activity: Membership types › Membership of board
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Vincere (External organisation)
Dario Alessi (Chair)
2019 → …Activity: Membership types › Membership of board