Alessi, Dario

Professor

https://orcid.org/0000-0002-2140-9185

United Kingdom

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Keywords

QH301 Biology
Biochemistry

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3 Not started
8 Active
43 Finished

Mouse Cell Line Characterisation (other inst: Rutgers University)
Alessi, D.
4/01/21 → 3/01/23
Project: Research
MRC PPU Covid Research
Alessi, D. & Davies, P.
Medical Research Council
18/10/20 → 17/07/21
Project: Research
ASAP - Mapping the LRRK2 Signalling Pathway and its Interplay with other Parkinson's Disease Components
Alessi, D. & Muqit, M.
1/10/20 → 30/09/23
Project: Research
Characterization of pT73 Rab10 Protein from XProChem and Supply of pRab8A and pRab10 Protein to Abcam for Assay Development
Alessi, D. & Davies, P.
1/01/20 → 14/08/21
Project: Research
Genome-wide and chemical screens to uncover novel upstream regulators of the LRRK2 signaling network
Alessi, D.
1/08/19 → 14/01/23
Project: Research

200 Article
4 Review article
3 Comment/debate
2 Meeting abstract
More

A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research
Rihn, S. J., Merits, A., Bakshi, S., Turnbull, M. L., Wickenhagen, A., Alexander, A. J. T., Baillie, C., Brennan, B., Brown, F., Brunker, K., Bryden, S. R., Burness, K. A., Carmichael, S., Cole, S. J., Cowton, V. M., Davies, P., Davis, C., De Lorenzo, G., Donald, C. L., Dorward, M. & 62 others, Dunlop, J. I., Elliott, M., Fares, M., da Silva Filipe, A., Freitas, J. R., Furnon, W., Gestuveo, R. J., Geyer, A., Giesel, D., Goldfarb, D. M., Goodman, N., Gunson, R., Hastie, C. J., Herder, V., Hughes, J., Johnson, C., Johnson, N., Kohl, A., Kerr, K., Leech, H., Lello, L. S., Li, K., Lieber, G., Liu, X., Lingala, R., Loney, C., Mair, D., McElwee, M. J., McFarlane, S., Nichols, J., Nomikou, K., Orr, A., Orton, R. J., Palmarini, M., Parr, Y. A., Pinto, R. M., Raggett, S., Reid, E., Robertson, D. L., Royle, J., Cameron-Ruiz, N., Shepherd, J. G., Smollett, K., Stewart, D. G., Stewart, M., Sugrue, E., Szemiel, A. M., Taggart, A., Thomson, E. C., Tong, L., Torrie, L. S., Toth, R., Varjak, M., Wang, S., Wilkinson, S. G., Wyatt, P. G., Zusinaite, E., Alessi, D. R., Patel, A. H., Zaid, A., Wilson, S. J. & Mahalingam, S., 25 Feb 2021, In: PLoS Biology. 19, 2, 22 p., e3001091.
Research output: Contribution to journal › Article › peer-review

Open Access
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5 Citations (Scopus)

16 Downloads (Pure)
Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms
Malik, A. U., Karapetsas, A., Nirujogi, R. S., Mathea, S., Chatterjee, D., Pal, P., Lis, P., Taylor, M., Purlyte, E., Gourlay, R., Dorward, M., Weidlich, S., Toth, R., Polinski, N. K., Knapp, S., Tonelli, F. & Alessi, D., 10 Feb 2021, In: Biochemical Journal. 478, 3, p. 553-578 26 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
16 Downloads (Pure)
Development of a multiplexed targeted mass spectrometry assay for LRRK2-phosphorylated Rabs and Ser910/Ser935 biomarker sites
Nirujogi, R. S., Tonelli, F., Taylor, M., Lis, P., Zimprich, A., Sammler, E. & Alessi, D. R., 22 Jan 2021, In: Biochemical Journal. 478, 2, p. 299-326 28 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
1 Citation (Scopus)

21 Downloads (Pure)
LRP10 interacts with SORL1 in the intracellular vesicle trafficking pathway in non-neuronal brain cells and localises to Lewy bodies in Parkinson's disease and dementia with Lewy bodies
Grochowska, M. M., Carreras Mascaro, A., Boumeester, V., Natale, D., Breedveld, G. J., Geut, H., van Cappellen, W. A., Boon, A. J. W., Kievit, A. J. A., Sammler, E., Parchi, P., Cortelli, P., Alessi, D. R., van de Berg, W. D. J., Bonifati, V. & Mandemakers, W., 28 Apr 2021, (E-pub ahead of print) In: Acta Neuropathologica. 21 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
4 Downloads (Pure)
R1441G but not G201S mutation enhances LRRK2 mediated Rab10 phosphorylation in human peripheral blood neutrophils
Sammler, E., Fan, Y., Nirujogi, R., Garrido, A., Ruiz-Martínez, J., Bergareche-Yarza, A., Mondragón Rezola, E., Vinagre Aragón, A., Croitoru, I., Gorostidi Pagola, A., Markinez, L. P., Alcalay, R., Hickman, R. A., Duering, J., Gomes, S., Pratuseviciute, N., Padmanabhan, S., Valldeoriola, F., Pérez Sisqués, L., Malagelada, C. & 5 others, Ximelis, T., Molina Porcel, L., José Martí, M., Tolosa, E. & Alessi, D., 14 Jun 2021, (E-pub ahead of print) In: Acta Neuropathologica. 20 p.
Research output: Contribution to journal › Article › peer-review

Open Access