Alessi, Dario

Professor

https://orcid.org/0000-0002-2140-9185

United Kingdom

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Personal profile

Keywords

QH301 Biology
Biochemistry

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2 Not started
11 Active
39 Finished

MRC PPU Covid Research
Alessi, D. & Davies, P.
Medical Research Council
18/10/20 → 17/07/21
Project: Research
ASAP - Mapping the LRRK2 Signalling Pathway and its Interplay with other Parkinson's Disease Components
Alessi, D. & Muqit, M.
1/10/20 → 30/09/23
Project: Research
World Class Labs
Alessi, D. & Davies, P.
Medical Research Council
1/10/20 → 31/03/21
Project: Research
Funding for new Mass Spec Platform
Alessi, D. & Davies, P.
1/04/20 → 31/03/21
Project: Research
Linking the GI tract with PD
Alessi, D., Mowat, C. & Sammler, E.
1/03/20 → 28/02/21
Project: Research

194 Article
4 Review article
3 Comment/debate
2 Meeting abstract
More

Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms
Malik, A. U., Karapetsas, A., Nirujogi, R. S., Mathea, S., Chatterjee, D., Pal, P., Lis, P., Taylor, M., Purlyte, E., Gourlay, R., Dorward, M., Weidlich, S., Toth, R., Polinski, N. K., Knapp, S., Tonelli, F. & Alessi, D., 18 Jan 2021, In: Biochemical Journal.
Research output: Contribution to journal › Article › peer-review

Open Access
Development of a multiplexed targeted mass spectrometry assay for LRRK2-phosphorylated Rabs and Ser910/Ser935 biomarker sites
Nirujogi, R. S., Tonelli, F., Taylor, M., Lis, P., Zimprich, A., Sammler, E. & Alessi, D. R., 22 Jan 2021, In: Biochemical Journal. 478, 2, p. 299-326 28 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
1 Downloads (Pure)
Accurate MS-based Rab10 phosphorylation stoichiometry determination as readout for LRRK2 activity in Parkinson's disease
Karayel, O., Tonelli, F., Virreira Winter, S., Geyer, P. E., Fan, Y., Sammler, E. M., Alessi, D., Steger, M. & Mann, M., 1 Sep 2020, In: Molecular & Cellular Proteomics. 19, 9, p. 1546-1560 15 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
50 Downloads (Pure)
Advances in elucidating the function of leucine-rich repeat protein kinase-2 in normal cells and Parkinson's disease
Taylor, M. & Alessi, D., Apr 2020, In: Current Opinion in Cell Biology. 63, p. 102-113 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
12 Citations (Scopus)

142 Downloads (Pure)
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
Gordon, D. E., Hiatt, J., Bouhaddou, M., Rezelj, V. V., Ulferts, S., Braberg, H., Jureka, A. S., Obernier, K., Guo, J. Z., Batra, J., Kaake, R. M., Weckstein, A. R., Owens, T. W., Gupta, M., Pourmal, S., Titus, E. W., Cakir, M., Soucheray, M., McGregor, M., Cakir, Z. & 40 others, Jang, G., O'Meara, M. J., Tummino, T. A., Zhang, Z., Foussard, H., Rojc, A., Zhou, Y., Kuchenov, D., Hüttenhain, R., Xu, J., Eckhardt, M., Swaney, D. L., Fabius, J. M., Ummadi, M., Tutuncuoglu, B., Rathore, U., Modak, M., Haas, P., Haas, K. M., Williams, D. M., Hastie, C. J., Elliott, M., Brown, F., Burness, K. A., Reid, E., Baillie, C., Raggett, S., Toth, R., Alessi, D. R., Davies, P., García-Sastre, A., Rassen, J. A., Grosse, R., Rosenberg, O. S., Verba, K. A., Basler, C. F., Vignuzzi, M., Peden, A. A., Beltrao, P. & Krogan, N. J., 4 Dec 2020, In: Science (New York, N.Y.). 370, 6521, 28 p., eabe9403.
Research output: Contribution to journal › Article › peer-review

Open Access
File
11 Citations (Scopus)

16 Downloads (Pure)