Alessi, Dario

Professor

    • United Kingdom

    1992 …2023

    Research output per year

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    Personal profile

    Keywords

    • QH301 Biology
    • Biochemistry

    Fingerprint Dive into the research topics where Dario Alessi is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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    Projects

    Research Output

    Open Access
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  • 23 Downloads (Pure)

    Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson’s Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation

    Fan, Y., Tonelli, F., Padmanabhan, S., Baptista, M., Riley, L., Smith, D., Marras, C., Howden, A., Alessi, D. & Sammler, E., 22 Mar 2020, In : JoVE: Journal of Visualized Experiments. 157, e58956.

    Research output: Contribution to journalArticle

  • Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2

    Waschbüsch, D., Purlyte, E., Pal, P., McGrath, E., Alessi, D. R. & Khan, A. R., 3 Feb 2020, In : Structure. 28, p. 1-12 12 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 24 Downloads (Pure)

    Crystal structure of the WD40 domain dimer of LRRK2

    Zhang, P., Fan, Y., Ru, H., Wang, L., Magupalli, V. G., Taylor, S. S., Alessi, D. R. & Wu, H., 29 Jan 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 5, p. 1579-1584 6 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 5 Citations (Scopus)
    119 Downloads (Pure)

    Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader

    Tovell, H., Testa, A., Zhou, H., Shpiro, N., Crafter, C., Ciulli, A. & Alessi, D., 20 Sep 2019, In : ACS Chemical Biology. 14, 9, p. 2024-2034 11 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 4 Citations (Scopus)
    74 Downloads (Pure)

    Thesis

    Advancing understanding of endogenous PINK1-Parkin signalling linked to Parkinson’s disease

    Author: Balk, K. R., 2019

    Supervisor: Muqit, M. (Supervisor) & Alessi, D. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    Biochemical characterisation of the Parkinson's disease-associated kinase PINK1: Insights from the insect world

    Author: Woodroof, H. I., 2014

    Supervisor: Muqit, M. (Supervisor), Van Aalten, D. (Supervisor) & Alessi, D. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File

    Exploring the contribution of SGK isoforms to signalling and mediating resistance to Akt inhibitors in breast cancer cells

    Author: Sommer, E., 2013

    Supervisor: Alessi, D. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File

    Investigating the role of PINK1-dependent Rab signalling in Parkinson's disease

    Author: Mulholland, K. E., 2019

    Supervisor: Muqit, M. (Supervisor) & Alessi, D. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    Investigation of regulation and downstream signaling pathway of Parkinson’s disease associated kinase, PINK1

    Author: Kondapalli, C., 2013

    Supervisor: Alessi, D. (Supervisor) & Muqit, M. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

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