Alessi, Dario

Professor

    • United Kingdom

    1992 …2020

    Research output per year

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    Personal profile

    Keywords

    • QH301 Biology
    • Biochemistry

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    Projects

    Research Output

    Accurate MS-based Rab10 phosphorylation stoichiometry determination as readout for LRRK2 activity in Parkinson's disease

    Karayel, O., Tonelli, F., Virreira Winter, S., Geyer, P. E., Fan, Y., Sammler, E. M., Alessi, D., Steger, M. & Mann, M., 29 Jun 2020, In : Molecular & Cellular Proteomics.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 4 Downloads (Pure)
    Open Access
    File
  • 1 Citation (Scopus)
    53 Downloads (Pure)

    Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson’s Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation

    Fan, Y., Tonelli, F., Padmanabhan, S., Baptista, M., Riley, L., Smith, D., Marras, C., Howden, A., Alessi, D. & Sammler, E., 22 Mar 2020, In : JoVE: Journal of Visualized Experiments. 157, e58956.

    Research output: Contribution to journalArticle

  • Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2

    Waschbüsch, D., Purlyte, E., Pal, P., McGrath, E., Alessi, D. R. & Khan, A. R., 7 Apr 2020, In : Structure. 28, 4, p. 406-417.e6 19 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 1 Citation (Scopus)
    36 Downloads (Pure)

    Crystal structure of the WD40 domain dimer of LRRK2

    Zhang, P., Fan, Y., Ru, H., Wang, L., Magupalli, V. G., Taylor, S. S., Alessi, D. R. & Wu, H., 29 Jan 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 5, p. 1579-1584 6 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 6 Citations (Scopus)
    133 Downloads (Pure)