Research Output per year
Personal profile
Keywords
- QH301 Biology
- Biochemistry
Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 15 Similar Profiles
Phosphotransferases
Medicine & Life Sciences
Phosphorylation
Chemical Compounds
Protein Kinases
Medicine & Life Sciences
Chemical activation
Chemical Compounds
Proto-Oncogene Proteins c-akt
Medicine & Life Sciences
3-Phosphoinositide-Dependent Protein Kinases
Medicine & Life Sciences
Leucine
Medicine & Life Sciences
Parkinson Disease
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 1992 2018
Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson’s disease kinase
Lis, P., Burel, S., Steger, M., Mann, M., Brown, F., Diez, F., Tonelli, F., Holton, J. L., Winglok Ho, P., Ho, S-L., Chou, M-Y., Polinski, N. K., Martinez, T. N., Davies, P. & Alessi, D. R., 2 Jan 2018, In : Biochemical Journal. 475, 1, p. 1-22Research output: Contribution to journal › Article
Open Access
File
Phospho-Specific Antibodies
Parkinson Disease
Phosphorylation
Phosphotransferases
Monoclonal Antibodies
Disruption of the with no lysine kinase^STE20-proline alanine-rich kinase pathway reduces thehypertension induced by angiotensin II
Graciela Cervantes-Perez, L., Castaneda-Bueno, M., Jimenez, J. V., Vazquez, N., Rojas-Vega, L., Alessi, D., Bobadilla, N. A. & Gamba, G., 1 Feb 2018, In : Journal of Hypertension. 36, 2, p. 361-367 7 p.Research output: Contribution to journal › Article
Open Access
File
Member 3 Solute Carrier Family 12
Proline
Angiotensin II
Alanine
Lysine
Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils
Fan, Y., Howden, A. J. M., Sarhan, A. R., Lis, P., Ito, G., Martinez, T. N., Brockmann, K., Gasser, T., Alessi, D. R. & Sammler, E., 2 Jan 2018, In : Biochemical Journal. 475, 1, p. 23-44 22 p.Research output: Contribution to journal › Article
Open Access
File
Phosphorylation
Parkinson Disease
Neutrophils
Phosphotransferases
Assays
LRRK2 is a negative regulator of phagosome maturation in macrophages
Härtlova, A., Herbst, S., Peltier, J., Rodgers, A., Bilkei-Gorzo, O., Fearns, A., Dill, B. D., Lee, H., Flynn, R., Cowley, S. A., Davies, P., Lewis, P. A., Ganley, I. G., Martinez, J., Alessi, D. R., Reith, A. D., Trost, M. & Gutierrez, M. G., 22 May 2018, In : The EMBO Journal. 2018, p. 1-17 17 p., e98694Research output: Contribution to journal › Article
Open Access
File
Phagosomes
Macrophages
Leucine
Phosphotransferases
Mycobacterium tuberculosis
LRRK2 kinase in Parkinson's disease
Alessi, D. R. & Sammler, E., 6 Apr 2018, In : Science. 360, 6384, p. 36-37 2 p.Research output: Contribution to journal › Comment/debate
Open Access
File
Leucine
Parkinson Disease
Phosphotransferases
Mutation
Clinical Trials, Phase I
Thesis
Biochemical characterisation of the Parkinson's disease-associated kinase PINK1: Insights from the insect world
Author: Woodroof, H. I., 2014Supervisor: Muqit, M. (Supervisor), Van Aalten, D. (Supervisor) & Alessi, D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
Exploring the contribution of SGK isoforms to signalling and mediating resistance to Akt inhibitors in breast cancer cells
Author: Sommer, E., 2013Supervisor: Alessi, D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
Investigation of regulation and downstream signaling pathway of Parkinson’s disease associated kinase, PINK1
Author: Kondapalli, C., 2013Supervisor: Alessi, D. (Supervisor) & Muqit, M. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
Investigation of the physiological function of TTBK2 (tau tubulin kinase 2), a protein kinase mutated in spinocerebellar ataxia type 11 (SCA11)
Author: Esoof, N., 2014Supervisor: Alessi, D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
Phosphorylation, ubiquitylation and characterisation of specific inhibitors of AMPK-related kinase NUAK1/ARK5
Author: Banerjee, S., 2013Supervisor: Alessi, D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File