Dario Alessi

Alessi, D. (Investigator), Davies, P. (Investigator), Ganley, I. (Investigator), Kulathu, Y. (Investigator), Liang, A. (Investigator), Rouse, J. (Investigator), Sapkota, G. (Investigator), Swamy, M. (Investigator), Swatek, K. (Investigator) & Virdee, S. (Investigator)

Project: Research

Exploiting state-of-the-art mass spectrometry to identify blood-based biomarkers for TDP-43 driven Motor Neuron Disease

Alessi, D. (Investigator) & Nirujogi, R. (Investigator)

Project: Research

Finished

World Class Labs Capital Equipment Funding Block Grant

Alessi, D. (Investigator) & Davies, P. (Investigator)

Medical Research Council

1/04/24 → 31/03/25

Project: Research

Linking the GI tract with PD

Alessi, D. (Investigator), Mowat, C. (Investigator) & Sammler, E. (Investigator)

1/10/23 → 30/09/24

Project: Research

Interrogating LRRK2 Signalling in Bio-Samples Derived From Patients with Parkinson's Disease Carrying the Asian LRRK2 G2385R and R1628P Variants for Biomarker Discovery (Joint with University of Malaya)

Alessi, D. (Investigator) & Sammler, E. (Investigator)

15/09/23 → 14/03/25

Project: Research

Validation Of LRRK2 Modifiers As Potential PD Therapeutic Targets - Joint with Universite de Lille and University of Padua

Alessi, D. (Investigator)

26/06/23 → 25/12/24

Project: Research

Capital Equipment Award. Shared Proteomics Platform For The MRC-PPU And The UK DRI

Alessi, D. (Investigator)

1/04/23 → 31/03/24

Project: Research

Development of LRRK2 Type II Inhibitors to Understand Utility of these Compounds for the Treatment of Parkinson's Disease

Alessi, D. (Investigator), Davies, P. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator) & Read, K. (Investigator)

1/03/23 → 29/02/24

Project: Research

MRC Capital Block Grant

Alessi, D. (Investigator) & Davies, P. (Investigator)

Medical Research Council

1/11/22 → 31/03/23

Project: Research

Ultra-High Definition Imaging - MRC Equipment Grant

Alessi, D. (Investigator), Banerjee, S. (Investigator), Cantley, J. (Investigator), Corner, G. (Investigator), Hayes, J. (Investigator), Hoskins, P. (Investigator), Kang, L. (Investigator), McNeilly, A. (Investigator), McSorley, H. (Investigator), Murdoch, C. (Investigator) & Rena, G. (Investigator)

Medical Research Council

1/11/22 → 31/03/23

Project: Research

LRRK2 Kinase Activity and Global Proteomic Markers in the Gut of PD and IBD Patients (Joint with Icahn School of Medicine Mount Sinai New York & Department Of Pathology & Immunology, Washington University School of Medicine)

Alessi, D. (Investigator) & Sammler, E. (Investigator)

1/07/22 → 31/08/24

Project: Research

High-Throughput-Analysis to Identify and Characterize PPM1H Protein Phosphatase Activity Enhancers

Alessi, D. (Investigator) & Davies, P. (Investigator)

1/02/22 → 1/02/24

Project: Research

MRC Climate Crisis Network (Lead: University Of Dundee other instns: Mitocondrial Unit, Human Genetics Unit)

Alessi, D. (Investigator) & Labib, K. (Investigator)

Medical Research Council

1/01/22 → 31/12/24

Project: Research

Cell Line Characterisation (other inst: Rutgers University)

Alessi, D. (Investigator)

1/11/21 → 31/10/23

Project: Research

Identifying PD Biomarkers In Peripheral Blood Immune Cells Using Mass Spectrometry And Single Cell RNA Sequencing

Alessi, D. (Investigator)

14/09/21 → 1/09/24

Project: Research

Differential LRRK2 Dependent Rab Phosphorylation Signatures in Peripheral Blood and Urine in Idiopathic and Monogenetic PD

Alessi, D. (Investigator) & Sammler, E. (Investigator)

1/06/21 → 31/07/24

Project: Research

World Class Labs Capital Funding Offer 2021/22

Alessi, D. (Investigator) & Davies, P. (Investigator)

Medical Research Council

1/04/21 → 31/03/22

Project: Research

World Class Labs Capital Award 21/22

Alessi, D. (Investigator) & Davies, P. (Investigator)

Medical Research Council

1/04/21 → 31/03/22

Project: Research

Stratification Of MRC Funded Scientific Technologies And Reagents For Rapid And Simple Dissemination To The Wider Scientific Community

Alessi, D. (Investigator) & Davies, P. (Investigator)

Medical Research Council

1/01/21 → 31/03/21

Project: Research

MRC PPU Covid Research

Alessi, D. (Investigator) & Davies, P. (Investigator)

Medical Research Council

18/10/20 → 17/07/21

Project: Research

World Class Labs

Alessi, D. (Investigator) & Davies, P. (Investigator)

Medical Research Council

1/10/20 → 31/03/21

Project: Research

ASAP - Mapping the LRRK2 Signalling Pathway and its Interplay with other Parkinson's Disease Components

Alessi, D. (Investigator) & Muqit, M. (Investigator)

Aligning Science Across Parkinson's (ASAP), Michael J. Fox Foundation for Parkinson's Research

1/10/20 → 1/10/24

Project: Research

Funding for new Mass Spec Platform

Alessi, D. (Investigator) & Davies, P. (Investigator)

1/04/20 → 31/03/21

Project: Research

Characterization of pT73 Rab10 Protein from XProChem and Supply of pRab8A and pRab10 Protein to Abcam for Assay Development

Alessi, D. (Investigator) & Davies, P. (Investigator)

1/01/20 → 14/08/21

Project: Research

PPM1H Activators for Treatment of Parkinson's Disease

Alessi, D. (Investigator) & Gray, D. (Investigator)

1/09/19 → 30/03/21

Project: Research

Genome-wide and chemical screens to uncover novel upstream regulators of the LRRK2 signaling network

Alessi, D. (Investigator)

1/08/19 → 30/09/21

Project: Research

MRC Capital Prioritisation Bid 2019-20

Alessi, D. (Investigator) & Davies, P. (Investigator)

Medical Research Council

1/04/19 → 31/03/20

Project: Research

Correlating LRRK2 Activation Status to Phospho-Lipids in Parkinson's Disease

Alessi, D. (Investigator) & Sammler, E. (Investigator)

1/11/18 → 31/12/20

Project: Research

LRRK2 and IBD

Alessi, D. (Investigator)

1/11/18 → 31/10/19

Project: Research

Regulation of the Parkinson's kinase LRRK2

Alessi, D. (Investigator)

Parkinson's UK

3/09/18 → 2/09/21

Project: Research

Investigation of the LRRK2 G2385R Mutation (joint with Chinese National Human Genome Center Beijing (SinoGenoMax), Xuanwu Hospital of Capital Medical University)

Alessi, D. (Investigator) & Davies, P. (Investigator)

1/08/18 → 31/12/20

Project: Research

MRC QQR

Alessi, D. (Investigator), Davies, P. (Investigator), Ganley, I. (Investigator), Kulathu, Y. (Investigator), Labib, K. (Investigator), Liang, A. (Investigator), Rouse, J. (Investigator), Rousseau, A. (Investigator), Sapkota, G. (Investigator), Virdee, S. (Investigator) & Walden, H. (Investigator)