Projects per year
- 1 - 50 out of 76 results
Search results
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Active
Mutational screen of GBA1, PARKIN and LRRK2
Alessi, D. (Investigator), Muqit, M. (Investigator) & Sammler, E. (Investigator)
1/08/24 → 31/07/26
Project: Research
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Interrogating Tankyrase-mediated Control of Neuronal Degeneration in Frontotemporal Dementia (Dementia Research Leader Fellowship) (Outline) & Full
Alessi, D. (Investigator), Ashford, M. (Investigator), Davies, P. (Investigator), McGurk, L. (Investigator) & Storey, K. (Investigator)
2/10/23 → 1/10/28
Project: Research
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Louis-Jeantet Prize 2023 - Personal Award
Alessi, D. (Investigator)
1/06/23 → 31/05/28
Project: Research
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Shared Proteomics Platform For The MRC PPU And The UK Dementia Research Institute (UK DRI)
Alessi, D. (Investigator)
1/04/23 → 31/03/28
Project: Research
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Implementation and Validation of Quantitative Lysosome-specific GCase Assays in Cell Lines and Human Peripheral Blood for use in Clinical Samples
Alessi, D. (Investigator) & Sammler, E. (Investigator)
1/03/23 → 31/08/25
Project: Research
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Not started
The Influenza Virus Toolkit: A Reagent Sharing Resource for Influenza Research (Joint with Universities of Glasgow and Oxford)
Alessi, D. (Investigator) & Davies, P. (Investigator)
Project: Research
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Single cell proteomics-Cellenone
Alessi, D. (Investigator) & Nirujogi, R. (Investigator)
Project: Research
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MRC QQR 2024-29
Alessi, D. (Investigator), Davies, P. (Investigator), Ganley, I. (Investigator), Kulathu, Y. (Investigator), Liang, A. (Investigator), Rouse, J. (Investigator), Sapkota, G. (Investigator), Swamy, M. (Investigator), Swatek, K. (Investigator) & Virdee, S. (Investigator)
Project: Research
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Exploiting state-of-the-art mass spectrometry to identify blood-based biomarkers for TDP-43 driven Motor Neuron Disease
Alessi, D. (Investigator) & Nirujogi, R. (Investigator)
Project: Research
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Finished
World Class Labs Capital Equipment Funding Block Grant
Alessi, D. (Investigator) & Davies, P. (Investigator)
1/04/24 → 31/03/25
Project: Research
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Linking the GI tract with PD
Alessi, D. (Investigator), Mowat, C. (Investigator) & Sammler, E. (Investigator)
1/10/23 → 30/09/24
Project: Research
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Interrogating LRRK2 Signalling in Bio-Samples Derived From Patients with Parkinson's Disease Carrying the Asian LRRK2 G2385R and R1628P Variants for Biomarker Discovery (Joint with University of Malaya)
Alessi, D. (Investigator) & Sammler, E. (Investigator)
15/09/23 → 14/03/25
Project: Research
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Validation Of LRRK2 Modifiers As Potential PD Therapeutic Targets - Joint with Universite de Lille and University of Padua
Alessi, D. (Investigator)
26/06/23 → 25/12/24
Project: Research
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Capital Equipment Award. Shared Proteomics Platform For The MRC-PPU And The UK DRI
Alessi, D. (Investigator)
1/04/23 → 31/03/24
Project: Research
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Development of LRRK2 Type II Inhibitors to Understand Utility of these Compounds for the Treatment of Parkinson's Disease
Alessi, D. (Investigator), Davies, P. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator) & Read, K. (Investigator)
1/03/23 → 29/02/24
Project: Research
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MRC Capital Block Grant
Alessi, D. (Investigator) & Davies, P. (Investigator)
1/11/22 → 31/03/23
Project: Research
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Ultra-High Definition Imaging - MRC Equipment Grant
Alessi, D. (Investigator), Banerjee, S. (Investigator), Cantley, J. (Investigator), Corner, G. (Investigator), Hayes, J. (Investigator), Hoskins, P. (Investigator), Kang, L. (Investigator), McNeilly, A. (Investigator), McSorley, H. (Investigator), Murdoch, C. (Investigator) & Rena, G. (Investigator)
1/11/22 → 31/03/23
Project: Research
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LRRK2 Kinase Activity and Global Proteomic Markers in the Gut of PD and IBD Patients (Joint with Icahn School of Medicine Mount Sinai New York & Department Of Pathology & Immunology, Washington University School of Medicine)
Alessi, D. (Investigator) & Sammler, E. (Investigator)
1/07/22 → 31/08/24
Project: Research
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High-Throughput-Analysis to Identify and Characterize PPM1H Protein Phosphatase Activity Enhancers
Alessi, D. (Investigator) & Davies, P. (Investigator)
1/02/22 → 1/02/24
Project: Research
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MRC Climate Crisis Network (Lead: University Of Dundee other instns: Mitocondrial Unit, Human Genetics Unit)
Alessi, D. (Investigator) & Labib, K. (Investigator)
1/01/22 → 31/12/24
Project: Research
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Cell Line Characterisation (other inst: Rutgers University)
Alessi, D. (Investigator)
1/11/21 → 31/10/23
Project: Research
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Identifying PD Biomarkers In Peripheral Blood Immune Cells Using Mass Spectrometry And Single Cell RNA Sequencing
Alessi, D. (Investigator)
14/09/21 → 1/09/24
Project: Research
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Differential LRRK2 Dependent Rab Phosphorylation Signatures in Peripheral Blood and Urine in Idiopathic and Monogenetic PD
Alessi, D. (Investigator) & Sammler, E. (Investigator)
1/06/21 → 31/07/24
Project: Research
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World Class Labs Capital Funding Offer 2021/22
Alessi, D. (Investigator) & Davies, P. (Investigator)
1/04/21 → 31/03/22
Project: Research
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World Class Labs Capital Award 21/22
Alessi, D. (Investigator) & Davies, P. (Investigator)
1/04/21 → 31/03/22
Project: Research
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Stratification Of MRC Funded Scientific Technologies And Reagents For Rapid And Simple Dissemination To The Wider Scientific Community
Alessi, D. (Investigator) & Davies, P. (Investigator)
1/01/21 → 31/03/21
Project: Research
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MRC PPU Covid Research
Alessi, D. (Investigator) & Davies, P. (Investigator)
18/10/20 → 17/07/21
Project: Research
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World Class Labs
Alessi, D. (Investigator) & Davies, P. (Investigator)
1/10/20 → 31/03/21
Project: Research
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ASAP - Mapping the LRRK2 Signalling Pathway and its Interplay with other Parkinson's Disease Components
Alessi, D. (Investigator) & Muqit, M. (Investigator)
Aligning Science Across Parkinson's (ASAP), Michael J. Fox Foundation for Parkinson's Research
1/10/20 → 1/10/24
Project: Research
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Funding for new Mass Spec Platform
Alessi, D. (Investigator) & Davies, P. (Investigator)
1/04/20 → 31/03/21
Project: Research
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Characterization of pT73 Rab10 Protein from XProChem and Supply of pRab8A and pRab10 Protein to Abcam for Assay Development
Alessi, D. (Investigator) & Davies, P. (Investigator)
1/01/20 → 14/08/21
Project: Research
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PPM1H Activators for Treatment of Parkinson's Disease
Alessi, D. (Investigator) & Gray, D. (Investigator)
1/09/19 → 30/03/21
Project: Research
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Genome-wide and chemical screens to uncover novel upstream regulators of the LRRK2 signaling network
Alessi, D. (Investigator)
1/08/19 → 30/09/21
Project: Research
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MRC Capital Prioritisation Bid 2019-20
Alessi, D. (Investigator) & Davies, P. (Investigator)
1/04/19 → 31/03/20
Project: Research
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Correlating LRRK2 Activation Status to Phospho-Lipids in Parkinson's Disease
Alessi, D. (Investigator) & Sammler, E. (Investigator)
1/11/18 → 31/12/20
Project: Research
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Regulation of the Parkinson's kinase LRRK2
Alessi, D. (Investigator)
3/09/18 → 2/09/21
Project: Research
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Investigation of the LRRK2 G2385R Mutation (joint with Chinese National Human Genome Center Beijing (SinoGenoMax), Xuanwu Hospital of Capital Medical University)
Alessi, D. (Investigator) & Davies, P. (Investigator)
1/08/18 → 31/12/20
Project: Research
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MRC QQR
Alessi, D. (Investigator), Davies, P. (Investigator), Ganley, I. (Investigator), Kulathu, Y. (Investigator), Labib, K. (Investigator), Liang, A. (Investigator), Rouse, J. (Investigator), Rousseau, A. (Investigator), Sapkota, G. (Investigator), Virdee, S. (Investigator) & Walden, H. (Investigator)
1/04/18 → 1/04/24
Project: Research
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MRC Capital Prioritisation
Alessi, D. (Investigator) & Davies, P. (Investigator)
1/04/18 → 31/03/19
Project: Research
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Validation of Abcam Rabbit anti-pS1292 LRRK Antibody
Alessi, D. (Investigator) & Davies, P. (Investigator)
27/09/17 → 26/09/18
Project: Research
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LRRK2 Inhibition to Systemic Bacterial Infection (Joint with Ottowa Hospital Research Institute)
Alessi, D. (Investigator)
1/07/17 → 30/06/19
Project: Research
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Chemical Knockdown of LRRK2 by Small Molecule Protacs (Joint with Dana-Farber Cancer Institute)
Alessi, D. (Investigator) & Davies, P. (Investigator)
2/11/16 → 13/08/18
Project: Research
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Towards a Unifying Theory of Parkinson's Disease - Investigation of the Biochemical and Genetic Role of Rab GTPases (joint with German Centre for Neurodegenerative Diseases)
Alessi, D. (Investigator) & Muqit, M. (Investigator)
17/10/16 → 16/10/18
Project: Research
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Rab Detection Initiative (Joint with Stanford School of Medicine, Max Plank Institute, Neuroscience Research Australia and Parkinsons Institute California)
Alessi, D. (Investigator) & Davies, P. (Investigator)
1/08/16 → 31/07/21
Project: Research
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Validation of Custom Rabbit Monoclonal Antibodies Directed to Rab8 a/b (Total Rab 8b, pT72 Rab 8a) and to Rab10 (total and pT73) made at Abcam
Alessi, D. (Investigator) & Davies, P. (Investigator)
1/08/16 → 31/01/18
Project: Research
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Understanding Regulation of Rabs by LRRK2 and Implications to Parkinson's Disease (joint with Max Planck Institute of Biochemistry and Stanford School of Medicine)
Alessi, D. (Investigator)
1/08/15 → 31/07/18
Project: Research